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Regenerative Biomaterials 2021年第2期8卷 149-162页

作者： Shuo Sun Zixue Jiao Yu wang Zhenxu Wu haowei wang Qingming Ji Yi Liu Zongliang wang Peibiao Zhang Department of Spine Surgery The First Hospital of Jilin University1 Xinmin StreetChangchun 130021China Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of Sciences5625 Renmin StreetChangchun 130022China

Porous microcarriers have aroused increasing attention recently by facilitating oxygen and nutrient transfer,supporting cell attachment and growth with sufficient cell seeding *** this study,porous polyetheretherketone(PEEK)microcarriers coated with mineralized extracellular matrix(mECM),known for their chemical,mechanical and biological superiority,were developed for orthopedic *** PEEK microcarriers were derived from smooth microcarriers using a simple wet-chemistry strategy involving the reduction of carbonyl *** treatment simultaneously modified surface topology and chemical ***,the microstructure,protein absorption,cytotoxicity and bioactivity of the obtained porous microcarriers were *** deposition of mECM through repeated recellularization and decellularization on the surface of porous MCs further promoted cell proliferation and osteogenic ***,the mECM coated porous microcarriers exhibited excellent bone regeneration in a rat calvarial defect repair model in vivo,suggesting huge potential applications in bone tissue engineering.

关键词： polyetheretherketone porous microcarriers mineralized extracellular matrix cell expansion bone regeneration

非编码RNA在甲基苯丙胺诱导成瘾及神经毒性作用的研究进展

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中国比较医学杂志 2024年第2期34卷 114-121页

作者：张树威程浩王浩伟苗霖李怡官莉娜曾晓锋国家卫健委毒品依赖和戒治重点实验室昆明医科大学法医学院昆明650500

甲基苯丙胺(methamphetamine,METH)具有高度成瘾性和神经毒性,可导致滥用者的认知和记忆功能障碍。METH的危害不仅在于其本身的毒性,更在于吸毒者身心的高度依赖性,常造成精神障碍并引发暴力行为,给社会带来极大的安全隐患。非编码RNA(n... 详细信息

甲基苯丙胺(methamphetamine,METH)具有高度成瘾性和神经毒性,可导致滥用者的认知和记忆功能障碍。METH的危害不仅在于其本身的毒性,更在于吸毒者身心的高度依赖性,常造成精神障碍并引发暴力行为,给社会带来极大的安全隐患。非编码RNA(non⁃coding RNA,ncRNA)不编码蛋白质,是在转录后水平调控基因表达的重要因子。研究表明,ncRNA在甲基苯丙胺诱导的成瘾及神经毒性中发挥了重要的调控作用,但其具体机制尚不清楚。本文就目前ncRNA调控METH诱导成瘾及神经毒性的研究进展进行综述,以期为ncRNA作为METH滥用者的法医学鉴定指标和潜在的药物干预靶点提供参考。

关键词：甲基苯丙胺非编码RNA 成瘾神经毒性

Measurement of dynamic membrane mechanosensation using optical tweezers

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Journal of Molecular Cell Biology 2021年第6期13卷 455-457页

作者： Xuanling Li Xing Liu Xiaoyu Song Yinmei Li Ming Li haowei wang Department of Optics and Optical Engineering University of Science and Technology of China and Hefei National Laboratory for Physical Sciences at the MicroscaleHefeiChina MOE Key Laboratory for Membraneless Organelles&Cellular Dynamics Anhui Key Laboratory for Cellular Dynamics and Chemical BiologyHefeiChina Department of Laboratory Diagnostics the First Affiliated HospitalUniversity of Science and Technology of ChinaHefeiChina

Many cellular processes are orchestrated by dynamic changes in the plasma membrane to form membrane projections and endocytic compartments in response to extracellular cue *** previous studies show that post-translational modifications of ACAP4 regulate membrane dynamics and curvature in response to epidermal growth factor and chemokine(C−C motif)ligand 18 stimulation(Zhao et al.,2013;Song et al.,2018).

关键词： dynamic curvature translational

Effects of in-situ TiB_(2)particles on machinability and surface integrity in milling of TiB_(2)/2024 and TiB_(2)/7075 Al composites

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Chinese Journal of Aeronautics 2021年第6期34卷 110-124页

作者： Jie CHEN Weiwei YU Zhenyu ZUO Yugang LI Dong CHEN Qinglong AN Jiwei GENG Ming CHEN haowei wang State Key Laboratory of Mechanical System and Vibration School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Anhui Aluminium Matrix Composites Engineering Research Centre 21 Weilong RoadHuaibei 235047China State Key Laboratory of Metal Marix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China

In-situ ceramics particle reinforced aluminum matrix composites are favored in the aerospace industry due to excellent ***,the hard ceramic particles as the reinforcement phase bring challenges to *** study the effect of in-situ TiB_(2)particles on machinability and surface integrity of TiB_(2)/2024 composite and TiB_(2)/7075 composite,milling experiments were performed,and compared with conventional 2024 and 7075 aluminum ***-situ TiB_(2)particles clustered at the grain boundaries and dispersed inside the matrix alloy grains hinder the dislocation movement of the matrix ***,the milling force and temperature of the composites are higher than those of the aluminum alloys due to the increase of the strength and the decrease of the *** the milling of composites,abrasive wear is the main wear form of carbide tools,due to the scratching of hard nano-TiB_(2)*** composites containing in-situ TiB_(2)particles have machining defects such as smearing,micro-scratches,micro-pits and tail on the machined ***,in-situ TiB_(2)particles impede the plastic deformation of the composites,which greatly reduces cutting edge marks on the machined ***,under the same milling parameters,the surface roughness of TiB_(2)/2024 composite and TiB_(2)/7075 composite is much less than that of2024 and 7075 aluminum alloy *** the milling conditions of this experiment,the machined subsurface has no metamorphic layer,and the microhardness of the machined surface is almost the same as that of the ***,compared with 2024 and 7075 aluminum alloy,machined surfaces of TiB_(2)/2024 composite and TiB_(2)/7075 composite both show tensile residual stress or low magnitude of compressive residual stress.

关键词： Aluminum matrix composites Machinability Milling Surface integrity TiB_(2)particle

基于蒙特卡罗方法的核事故碎块辐射场模拟计算

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火箭军工程大学学报

火箭军工程大学学报 2024年第2期38卷 32-38页

作者：王浩伟蔡幸福郭晓辉霍勇刚火箭军工程大学

针对核事故产生的材料碎块可能会沾染放射性物质的问题，为弥补之前研究中未涉及的碎块辐射场分布水平的不足，分析了其分布的影响因素，基于蒙特卡罗法，利用SuperMC程序分别研究了核事故碎块姿态、碎块被土壤掩埋的深度、碎块材料分... 详细信息

针对核事故产生的材料碎块可能会沾染放射性物质的问题，为弥补之前研究中未涉及的碎块辐射场分布水平的不足，分析了其分布的影响因素，基于蒙特卡罗法，利用SuperMC程序分别研究了核事故碎块姿态、碎块被土壤掩埋的深度、碎块材料分层截面形状对辐射场分布的影响。结果表明：碎块姿态主要影响辐射场的分布形状；碎块掩埋深度会对辐射剂量率造成较大影响，碎块在被土壤完全掩埋后，其地面剂量率峰值比完全裸露时低2个数量级；分层截面形状的影响较小。

关键词：辐射场蒙特卡罗法核事故应急模拟计算

High-resolution, full-color quantum dot light-emitting diode display fabricated via photolithography approach

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Nano Research 2020年第9期13卷 2485-2491页

作者： Wenhai Mei Zhenqi Zhang Aidi Zhang Dong Li Xiaoyuan Zhang haowei wang Zhuo Chen Yanzhao Li Xinguo Li Xiaoguang Xu BOE Technology Group Co. Ltd.Beijing 100176China School of Software&Microelectronics Department Peking UniversityBeijing 102600China

Displays play an extremely important role in modern information society,which creates a never-ending demand for the new and better products and *** latest requirements for novel display technologies focus on high resolution and high color *** emerging technologies that include organic light-emitting diode(OL ED),micro light-emiting diode(micro-LED),quantum dot light-emitting diode(QLED),laser display,holographic display and others,QLED is promising owing to its intrinsic high color gamut and the possibility to achieve high resolution with photolithography ***,previously demonstrated photolthography techniques suffer from reduced device performance and color Impurities in subpixels from the *** this study,we demonstrated a sacrificial layer assisted patterming(SLAP)approach,which can be applied in conjunction with photolithography to fabricate high-resolution,full-colo quantum dot(QD)*** this approach,the negative photoresist(PR)and sacrificial layer(SL)were uilized to determine the pixels for QD deposition,while at the same time the SL helps protect the QD layer and keep it intact(named PR-SL approach).To prove this method's viability for QLED display manufacture,a 500-ppi,full-color passive matrix(PM)-QLED prototype was fabricated via this *** show that there were no color impurities in the subpixels,and the PM-QL ED has a high color gamut of 114%National Television Standards Committee(NTSC).To the best of our knowledge,this is the first ull-olor QLED prototype with such a high *** anticipate that this innovative patteming technique will open a new horizon for future display technologies and may lead to a disruptive and innovative change in display industry.

关键词： quantum dots sacrificial layer assisted patterning quantum dot light-emitting diodes photolithography high-resolution

INTERACTION　OF　PARTICLES　WITH　A　SOLIDIFIED　INTERFACE　DURING　SOLIDIFICATION　OF　METAL　MATRIX　COMPOSITE　REINFORCED　WITH　PARTICLES

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Acta Metallurgica Sinica(English Letters) 1996年第1期9卷 71-78页

作者： CHU Shuangjie wang haowei WU Renjie LIN Xiaotang(Institute of Composite Materials,Shanghai Jiaotong University,Shanghai 200030,China Shanghai Jiaotong Univ Shanghai China

The interaction of particles with a solid-liquid interface during solidification of metal matrix composites has been investigated theoretically in this *** to the presence of particles in the melt,the shape of the solidification front and solute concentration field in front of solidification interface have been disturbed The thermodynamic method was employed,and a mathematical expression of the shape of the solidification interface and solute concentration field were ***,a theory is developed for evaluation of critical velocities of particles pushed by the solidification interface.A numerical simulation is done in which the critical velocity is evaluated as a function of particle size,thermal conductivity,diffusion coefficient,temperature gradient at the solidification front,the solid-liquid interfacial energy and the melt *** critical velocity is shown to be closely linked to the shape of the solidification interface and solute concentration field, and hence all the parameters also affect the shape of the solidification interface and solute concentration field of the front.

关键词： metal matrix composite solid-liquid interface interaction solidification

Reader Management and Coordination Component based on Rfid

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International Journal of Technology Management 2013年第2期 97-99页

作者： wang haowei Yang Shuhui College of Information and Communication Engineering Beijing Information Science and Technology University Beijingl00101

RFID has the advantages of waterproof, antimagnetic, heat resistance, long service life, great reading distance, encrypting data on label, greater capacity of storing data and free modification on stored information compared with bar code. Applying it brings revolutionary change to the retail and logistics industry. Selecting technology to manage RFID and selecting strategy to coordinate RFID is very important to promote the application of RFID. The paper implements RFtD management system, ALE engine and data processing components, and expounds the technique and details implementing the system.

关键词： RFID middleware reader management reader coordination

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晶格结构可打印性研究现状

铸造技术 2024年第9期45卷 822-837页

作者：邓锦涛吴一高振洋任芃源孙华刘兴天王浩伟王洪泽上海交通大学材料科学与工程学院金属基复合材料国家重点实验室上海200240 上海交通大学安徽(淮北)陶铝新材料研究院安徽淮北235000 上海卫星工程研究所上海201109

晶格结构因其复杂多变的结构呈现出多种优异的电、磁、声学、热学和机械性能,在航空航天、汽车、建筑和生物医学行业显示出较大的市场前景,而晶格结构的制造难度大是制约其快速发展的一大难题,增材制造技术为晶格结构制造带来了便利。... 详细信息

晶格结构因其复杂多变的结构呈现出多种优异的电、磁、声学、热学和机械性能,在航空航天、汽车、建筑和生物医学行业显示出较大的市场前景,而晶格结构的制造难度大是制约其快速发展的一大难题,增材制造技术为晶格结构制造带来了便利。本文主要总结分析了晶格结构的设计、打印原材料和打印过程中参数对结构可打印性的影响,分析得出晶格结构的可打印性受晶格类型、相对密度、支柱倾斜度、粉末类型和打印参数的影响,最后提出了提升晶格可打印性的未来发展方向。

关键词：晶格结构增材制造粉末特性无支撑

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基于不同优化策略的国六汽车起重机排放特性研究

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南方农机 2024年第2期55卷 154-158页

作者：高洁贾佳奇杨锦天董庆奇董浩王浩伟罗天娇中机科(北京)车辆检测工程研究院有限公司北京102100 国家工程机械质量检验检测中心北京102100 中机寰宇(山东)车辆认证检测有限公司山东德州253000

为了有效控制重型柴油车排放水平,改善大气质量。选取一辆N3类国六重型汽车起重机,采集PEMS路谱,按照PEMS工况曲线在底盘测功机上开展不同优化策略下的排放测试。结果表明:国六重型汽车起重机现有的后处理技术路线可以有效控制NOx、CO、... 详细信息

为了有效控制重型柴油车排放水平,改善大气质量。选取一辆N3类国六重型汽车起重机,采集PEMS路谱,按照PEMS工况曲线在底盘测功机上开展不同优化策略下的排放测试。结果表明:国六重型汽车起重机现有的后处理技术路线可以有效控制NOx、CO、CO_(2)和PN排放,但相对于正常状态下的车辆,采用不同的优化策略使得排放有所上升,尤其是NOx和PN,上升效果更为明显,平均提高了60%~90%。NOx比排放随速度的增加而降低,具体表现为市区>市郊>高速,比排放最高的区域出现在市区工况。车辆经过累碳(4 h和8 h)后的碳载量对NOx排放并无明显影响。此外,NOx瞬时排放和排气流量、行驶速度呈现正相关。优化扭矩响应和尿素喷射策略导致CO排放量急剧增加,排气温度和排气流量也会对DOC装置氧化CO产生不良影响。虽然高速工况下发动机负荷增加、缸内缺氧使得燃烧不充分,CO瞬时排放增加,但是此时发动机功率较高,导致CO比排放处于较低水平。CO_(2)比排放总体较为稳定,个体间差异不大。PN排放与车辆行驶速度、发动机负荷存在很大关系。优化喷嘴喷射和尿素喷射策略导致PN排放成倍增加。从整体来看,汽车起重机污染物排放结果均远低于国六排放标准限值,表明下阶段排放标准污染物排放限值仍有较大下降空间。

关键词：汽车起重机 PEMS工况优化策略排放特性