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An improved siphon drainage method for slope stabilization

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Journal of Mountain Science 2019年第3期16卷 701-713页

作者： SUN Hong-yue wang dong-fei SHANG Yue-quan CAI Yue-liang WEI Zhen-lei Ocean College Zhejiang University College of Civil Engineering and Architecture Zhejiang University

The siphon drainage is an effective measure for the slope groundwater control. However,for the traditional siphon drainage, limitations such as siphon lift restriction and poor reliability in longterm service prevent it from being widely used. In this study, an improved siphon drainage method with inclined borehole penetrating the deep part of the slope is proposed to overcome the limitations suffered by the traditional method. Through experimental research, theoretical analysis and engineering practice,the reliability and capability of the proposed method are investigated. The results demonstrate that with the inclined pipe the height difference between the control point of the groundwater level and the orifice can be controlled to be less than the height of the water column corresponding to the local atmospheric pressure. As a result, deep drainage can be *** addition, by controlling the diameter of siphon drainage pipe not larger than 4 mm, a plug flow can be formed in the siphon pipe, which can prevent air accumulation in the siphon process and a continuous and effective siphon drainage is achieved. Through a practical project running smoothly since September 2013, it is found that the proposed method can effectively drain the groundwater deep in the slope and the maximum drawdown of groundwater level in boreholes can reach 8.5 m with an average drainage flow of 5.5 m3/d. The practical results also illustrate that 4 mm siphon pipe can be used to realize deep slope drainage and restart siphon automatically.

关键词： Landslide Drainage Siphon Inclined borehole 4mm diameter siphon pipe

Root structure of slope protection plants in a high-grade highway

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Journal of Forestry Research 2011年第2期22卷 311-313页

作者： wang Jing-hong LI Xing-tao LIU Xiao-dong wang fei LIU Yu College of Landscape Architecture Northeast Forestry University Harbin150040 Heilongjiang China.

Root length and root length density of Lespedeza bicolor,Amorpha fruticosa,and Sea buckthorn were investigated in a country highway-TongSan highway（Tongjiang to Sanya） in Heilongjiang Province,*** root lengths were divided into five root orders according to Pregizter sequence classification *** show that sea buckthorn roots are dominated by coarse roots in the horizontal growth,while *** has a large proportion of fine roots in vertical conical growth and *** is in depth *** length density of *** in all the root sequences is higher than that of sea buckthorn and *** the basis of the root structure,it is inferred that *** roots mainly absorb the surface soil moisture for its normal growth;in contrast,*** has good uptake ability to deep soil *** root structure of sea buckthorn implies that it has a strong drought resistance.

关键词： seasonal frost area slope protection plant root structure

Heme oxygenase-1 regulates the major route involved in formation of immune hepatic fibrosis in rats

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Chinese Medical Journal 2010年第22期123卷 3304-3308页

作者： DUAN Zhi-jun YANG dong wang fei SUN Ying-jie SUN Xiao-yu ZHENG Miao-lei Department of Gastroenterology First Affiliated Hospital of Dalian Medical University Dalian Liaoning 116011 China

Background Heme oxygenase （HO） plays roles in some liver diseases, but what it does in immune liver fibrosis is rarely reported. We investigated the regulation mechanisms of HO-1 in rat immune liver fibrosis to find routes for intervention. Methods Male Sprague-Dawley rats were randomly divided into control group （N, n=-12）, fibrosis group （F, n=20）, cobalt protoporphyrin （CoPP） inducing group （Co, n=20） and zinc protoporphyrin （ZnPP） inhibiting group （Zn, n=20）. In groups F, Co and Zn, immune liver fibrosis was established with human serum albumin. At the attacked stage, CoPP （5 mg/kg） and ZnPP （5 mg/kg） were intraperitoneally injected in groups Co and Zn, respectively. After establishment of rat models, the numbers of rats reduced to 11, 15, 17 and 12 in groups N, F, Co and Zn respectively, because of death during the process. HO-1 in liver was detected by Western blotting and immunohistochemistry. The indexes of fibrosis were assessed by radioimmunoassay. Concentrations of serum transforming growth factor-β1 （TGF-β1）, and tissue inhibitor of metalloproteinses （TIMP-1） were detected using enzyme-linked immunosorbent assay. Hepatic stellate cell （HSC） and proliferation degree of fibrosis were assessed by pathological examination. Data analysis was performed by SPSS 10.0 software. Results The expression of HO-1 in group F was significantly higher than that in group N, but lower than that in group Co （P 〈0.05）; while that in group Zn was lower than in group F （P 〈0.05）, but still higher than that in group N （P 〈0.01）. Compared with group N, liver functional and liver fibrosis indicators were increased in group F （P 〈0.01）, while comparing to group F, they were decreased in group Co （P 〈0.05） and increased in group Zn （P 〈0.05）. CoPP reduced the extent of hepatocellular injury and hepatic fibrosis in comparison with group F （P 〈0.01）, being the opposite effect of ZnPP （P 〈0.01）. HSC was observed using indirect method and the result showed that the number of HSC in gro

关键词： heme oxygenase-1 immune fibrosis rats

2010-2014年杭州市萧山区疟疾流行特征分析

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中国血吸虫病防治杂志 2015年第6期27卷 653-654页

作者：林君英王冬飞浙江省杭州市萧山区疾病预防控制中心杭州311203

目的分析2010-2014年启动消除疟疾行动以来萧山区疟疾流行特征,评价消除疟疾工作效果,为制定适合本区实际的疟疾防治措施提供依据。方法利用中国疾病预防控制中心疾病监测信息报告管理系统以及疟疾疫情个案调查表,收集2010-2014年萧山... 详细信息

目的分析2010-2014年启动消除疟疾行动以来萧山区疟疾流行特征,评价消除疟疾工作效果,为制定适合本区实际的疟疾防治措施提供依据。方法利用中国疾病预防控制中心疾病监测信息报告管理系统以及疟疾疫情个案调查表,收集2010-2014年萧山区疟疾疫情数据资料,用Excel 2003进行统计分析。结果 2010-2014年萧山区共监测报告疟疾病例25例,年报告发病率在（0.09~0.38）/10万之间。监测报告病例均为实验室确诊病例,其中间日疟占48.00%（12例）,恶性疟占52.00%（13例）,无死亡病例发生。患者以青壮年为主,主要为境外务工或经商人员;国内省外输入性病例8例,境外输入性病例17例,分别占32.00%和68.00%,无本地感染病例报告。结论萧山区疟疾发病率继续保持在较低水平,感染来源已从省外感染和境外感染结合为主转向境外感染。今后需加强境外输入性疟疾疫情的监测和处置。

关键词：疟疾流行特征监测萧山区

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基于生态循环的村镇住区能源规划利用

山东农业大学学报（自然科学版） 2013年第1期44卷 96-101页

作者：王东飞徐学东山东农业大学水利土木工程学院山东泰安271018

目前村镇住区采用的能源基本上是不可再生的化石能源,而我国村镇地区的可再生能源储备非常丰富,在村镇住区规划中考虑可再生能源尤其是生物质能源的利用,最大限度地替代不可再生能源,对实现我国十二五能源战略目标非常重要。本文针对村... 详细信息

目前村镇住区采用的能源基本上是不可再生的化石能源,而我国村镇地区的可再生能源储备非常丰富,在村镇住区规划中考虑可再生能源尤其是生物质能源的利用,最大限度地替代不可再生能源,对实现我国十二五能源战略目标非常重要。本文针对村镇住区能源规划利用中存在的问题,探讨了基于生态循环理论的村镇住区能源规划设计方法,并以山东省沂水县马家林村为例,说明了该方法的具体应用,以期对快速城市化地区村镇能源的利用起到示范作用。

关键词：村镇住区能源循环系统能源规划利用节能

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弹性层状半平面的位移不连续基本解

上海交通大学学报 2009年第10期43卷 1676-1680页

作者：王飞董越鹏黄醒春上海交通大学土木工程系上海200240

为了得到弹性层状半平面的位移不连续基本解,从平面应变条件下的弹性力学基本方程出发,利用Airy应力函数并采用Fourier积分变换求解方程,得到了各层之间的传递矩阵和弹性半无限空间的刚度矩阵表达式.在求得传递矩阵和刚度矩阵的基础上,... 详细信息

为了得到弹性层状半平面的位移不连续基本解,从平面应变条件下的弹性力学基本方程出发,利用Airy应力函数并采用Fourier积分变换求解方程,得到了各层之间的传递矩阵和弹性半无限空间的刚度矩阵表达式.在求得传递矩阵和刚度矩阵的基础上,结合边界条件及各层间的连续性条件求解,再进行Fourier反变换,得到弹性含任意多层的半平面中直线段上作用均匀分布法向或切向不连续位移的基本解.通过与己有的弹性半平面位移不连续基本解进行对照,验证了推导的正确性,并给出了一个数值算例.结果表明:传递矩阵-刚度矩阵法解决层状问题简单有效;积分变换方法是求基本解问题的一种理想的方法.

关键词：弹性层状半平面位移不连续法基本解 Fourier变换

Prognostic model for esophagogastric variceal rebleeding after endoscopic treatment in liver cirrhosis: A Chinese multicenter study

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World Journal of Gastroenterology 2025年第2期31卷 85-101页

作者： Jun-Yi Zhan Jie Chen Jin-Zhong Yu fei-Peng Xu fei-fei Xing De-Xin wang Ming-Yan Yang Feng Xing Jian wang Yong-Ping Mu Cell Biology Laboratory Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Institute of Liver Diseases Shanghai Academy of Chinese MedicineShanghai 201203China Clinical Key Laboratory of Traditional Chinese Medicine of Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Key Laboratory of Liver and Kidney Disease of the Ministry of Education Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Gastroenterology and Hepatology Zhongshan Hospital Affiliated to Fudan UniversityShanghai 200032China Shanghai Institute of Liver Disease Fudan UniversityShanghai 200032China Evidence-Based Medicine Center Fudan UniversityShanghai 200032China Department of Gastrointestinal Endoscopy Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Hepatology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China

BACKGROUND Rebleeding after recovery from esophagogastric variceal bleeding(EGVB)is a severe complication that is associated with high rates of both incidence and *** its clinical importance,recognized prognostic models that can effectively predict esophagogastric variceal rebleeding in patients with liver cirrhosis are *** To construct and externally validate a reliable prognostic model for predicting the occurrence of esophagogastric variceal *** This study included 477 EGVB patients across 2 cohorts:The derivation cohort(n=322)and the validation cohort(n=155).The primary outcome was rebleeding events within 1 *** least absolute shrinkage and selection operator was applied for predictor selection,and multivariate Cox regression analysis was used to construct the prognostic *** validation was performed with bootstrap *** assessed the discrimination,calibration and accuracy of the model,and performed patient risk *** Six predictors,including albumin and aspartate aminotransferase concentrations,white blood cell count,and the presence of ascites,portal vein thrombosis,and bleeding signs,were selected for the rebleeding event prediction following endoscopic treatment(REPET)*** predicting rebleeding within 1 year,the REPET model ex-hibited a concordance index of 0.775 and a Brier score of 0.143 in the derivation cohort,alongside 0.862 and 0.127 in the validation ***,the REPET model revealed a significant difference in rebleeding rates(P<0.01)between low-risk patients and intermediate-to high-risk patients in both *** We constructed and validated a new prognostic model for variceal rebleeding with excellent predictive per-formance,which will improve the clinical management of rebleeding in EGVB patients.

关键词： Esophagogastric variceal bleeding Variceal rebleeding Liver cirrhosis Prognostic model Risk stratification Secondary prophylaxis

杭州市萧山区1988年至2009年甲状腺癌发病分析

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中华内分泌代谢杂志 2010年第10期26卷 843-846页

作者：王冬飞李毅本杭州市萧山区疾病预防控制中心慢性病防制科 311201

目的了解杭州市萧山区1988年至2009年甲状腺癌的发病情况及变化趋势.方法利用萧山区1988年至2009年甲状腺癌发病数据及历年人口资料,计算分年及分年龄段粗发病率、应用线性趋势检验作时间趋势分析.结果近20年来,萧山区甲状腺癌发病... 详细信息

目的了解杭州市萧山区1988年至2009年甲状腺癌的发病情况及变化趋势.方法利用萧山区1988年至2009年甲状腺癌发病数据及历年人口资料,计算分年及分年龄段粗发病率、应用线性趋势检验作时间趋势分析.结果近20年来,萧山区甲状腺癌发病率呈显著上升趋势,女性尤其明显;2009年女性甲状腺癌发病率达23.81/10万,占女性恶性肿瘤发病的7.66%,居女性恶性肿瘤发病第3位.甲状腺癌发病年龄男性和女性有较大区别,女性45～59岁为发病高峰,发病占恶性肿瘤总发病人数的40.26%,男性则随着年龄增长发病率逐步增加.结论萧山区甲状腺癌尤其是女性甲状腺癌发病近年来明显上升,其预防与控制应该成为萧山肿瘤控制计划制定和实施的重点之一.

关键词：甲状腺肿瘤发病率

Interaction of major facilitator superfamily domain containing 2A with the blood-brain barrier

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Neural Regeneration Research 2025年第8期20卷 2133-2152页

作者： Yilun Ma Taiwei dong fei Luan Juanjuan Yang Feng Miao Peifeng Wei College of Pharmacy and First Clinical Medical College Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina National Drug Clinical Trial Agency The Second Affiliated Hospital of Shaanxi University of Chinese Medicine/Xixian New District Central HospitalXi′anShaanxi ProvinceChina

The functional and structural integrity of the blood-brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms underlying the formation and function of the blood-brain barrier remain poorly *** major facilitator superfamily domain containing 2A has been identified as a key regulator of blood-brain barrier *** plays a critical role in promoting and maintaining the formation and functional stability of the blood-brain barrier,in addition to the transport of lipids,such as docosahexaenoic acid,across the blood-brain ***,an increasing number of studies have suggested that major facilitator superfamily domain containing 2A is involved in the molecular mechanisms of blood-brain barrier dysfunction in a variety of neurological diseases;however,little is known regarding the mechanisms by which major facilitator superfamily domain containing 2A affects the blood-brain *** paper provides a comprehensive and systematic review of the close relationship between major facilitator superfamily domain containing 2A proteins and the blood-brain barrier,including their basic structures and functions,cross-linking between major facilitator superfamily domain containing 2A and the blood-brain barrier,and the in-depth studies on lipid transport and the regulation of blood-brain barrier *** comprehensive systematic review contributes to an in-depth understanding of the important role of major facilitator superfamily domain containing 2A proteins in maintaining the structure and function of the blood-brain barrier and the research progress to *** will not only help to elucidate the pathogenesis of neurological diseases,improve the accuracy of laboratory diagnosis,and optimize clinical treatment strategies,but it may also play an important role in prognostic *** addition,the effects of major facilitator superfamily domain containing 2A on blood-brain barrier lea

关键词： blood-brain barrier(BBB) caveolin-1 central nervous system docosahexaenoic acid endothelial cells lysophosphatidylcholine major facilitator superfamily domain containing 2A(MFSD2A) transcytosis