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Regulating ion transport behaviors toward dendrite-free potassium metal batteries:recent advances and perspectives

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Rare Metals 2024年第4期43卷 1435-1460页

作者： Lu-Kang Zhao Xuan-Wen Gao Tian-Zhen Ren da wang da-Wei wang Zhao-Meng Liu Hong Chen Wen-Bin Luo School of Metallurgy Northeastern UniversityShenyang110819China School of Chemical Engineering The University of New South WalesSydneyNSW2052Australia

With abundant potassium resources and high capacity,potassium metal batteries(PMBs)present a compelling option for the next generation of energy storage ***,PMBs suffer from an unstable anode interface caused by uncontrolled dendrite growth,which results in unsatisfactory cyclability and safety *** investigations suggest that significant progress has been made in enhancing the interfacial stability of *** various effective strategies for stabilizing interfaces can ultimately be attributed to the regulation of the sluggish ion transfer kinetics and irregular deposition,i.e.,the arrangement of ion transport behaviors at the *** modulation of ions transport rate and ions deposition directions makes it possible to obtain a dendrite-free and smooth deposition ***,the influencing factors and action mechanism of K^(+)interface transport behaviors are discussed to understand the nature of material design for constructing stable anode interfaces,including regulating the solvation and desolvation structures,accelerating K^(+)transport kinetics and controlling K^(+)deposition *** addition,the deficiencies and prospects of the research on electrolyte,separators and designed electrode involved in the manufacturing and testing and ion transport process of PMBs are *** review is expected to provide some possible directions for constructing dendrite-free interfaces in advanced PMBs-related research and offer significant insights for prospective experimental research and commercial applications.

关键词： Ion transport rate Ion transport direction Interface Potassium metal batteries Dendrites growth

Efficacy of ginseng-based Renshenguben oral solution for cancer-related fatigue among patients with advanced-stage hepatocellular carcinoma:A prospective multicenter cohort study

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 249-256页

作者： Ming-da wang Chen Yuan Ke-Chun wang Nan-Ya wang Ying-Jian Liang Hong Zhu Xiang-Min Tong Tian Yang Department of Hepatobiliary and Pancreatic Surgery General Surgery CenterFirst Hospital of Jilin UniversityChangchun 130021China Department of Hepatobiliary Surgery Eastern Hepatobiliary Surgery HospitalSecond Military Medical University(Naval Medical University)Shanghai 200438China Department of Clinical Laboratory Laboratory Medicine CenterZhejiang Provincial People’s HospitalHangzhou Medical CollegeHangzhou 310000China Department of Hepatobiliary Surgery First Affiliated Hospital of Harbin Medical UniversityHarbin 150007China Department of Medical Oncology First Affiliated Hospital of Soochow UniversitySuzhou 215006China fDepartment of Central Laboratory Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhou 310006China

Background:Cancer-related fatigue(CRF)is a common and debilitating symptom experienced by patients with advanced-stage cancer,especially those undergoing antitumor *** study aimed to evaluate the efficacy and safety of Renshenguben(RSGB)oral solution,a ginseng-based traditional Chinese medicine,in alleviating CRF in patients with advanced hepatocellular carcinoma(HCC)receiving antitumor ***:In this prospective,open-label,controlled,multicenter study,patients with advanced HCC at BCLC stage C and a brief fatigue inventory(BFI)score of≥4 were *** were assigned to the RSGB group(RSGB,10 mL twice daily)or the control group(with supportive care).Primary and secondary endpoints were the change in multidimensional fatigue inventory(MFI)score,and BFI and functional assessment of cancer therapy-hepatobiliary(FACT-Hep)scores at weeks 4 and 8 after *** events(AEs)and toxicities were ***:A total of 409 participants were enrolled,with 206 assigned to the RSGB *** week 4,there was a trend towards improvement,but the differences were not statistically *** week 8,the RSGB group exhibited a significantly lower MFI score(P<0.05)compared to the control group,indicating improved fatigue ***,the RSGB group showed significantly greater decrease in BFI and FACT-Hep scores at week 8(P<0.05).Subgroup analyses among patients receiving various antitumor treatments showed similar *** linear regression analyses revealed that the RSGB group experienced a significantly substantial decrease in MFI,BFI,and FACT-Hep scores at week *** serious drug-related AEs or toxicities were ***:RSGB oral solution effectively reduced CRF in patients with advanced HCC undergoing antitumor therapy over an eight-week period,with no discernible *** findings support the potential of RSGB oral solution as an adjunctive treatment for managing CRF in this patient population.

关键词： Cancer-related fatigue Hepatocellular carcinoma Renshenguben oral solution Efficacy Safety Ginseng

Combining systemic inflammatory response index and albumin fibrinogen ratio to predict early serious complications and prognosis after resectable gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 732-749页

作者： Jing-Yao Ren da wang Li-Hui Zhu Shuo Liu Miao Yu Hui Cai School of Clinical Medicine Ningxia Medical UniversityYinchuan 750000Ningxia Hui Autonomous RegionChina General Surgery Clinical Medical Center Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina Medical College of Jiangsu University Jiangsu UniversityZhenjiang 212013Jiangsu ProvinceChina The First Clinical Medical School Lanzhou UniversityLanzhou 730000Gansu ProvinceChina

BACKGROUND Gastric cancer has a high incidence and fatality rate,and surgery is the preferred course of ***,patient survival rates are still low,and the incidence of major postoperative complications cannot be *** systemic inflammatory response,nutritional level,and coagulation status are key factors affecting the postoperative recovery and prognosis of gastric cancer *** systemic inflammatory response index(SIRI)and the albumin fibrinogen ratio(AFR)are two valuable comprehensive indicators of the severity and prognosis of systemic inflammation in various medical *** To assess the clinical importance and prognostic significance of the SIRI scores and the AFR on early postoperative outcomes in patients undergoing radical gastric cancer *** We conducted a retrospective analysis of the clinicopathological characteristics and relevant laboratory indices of 568 gastric cancer patients from January 2018 to December *** calculated and compared two indicators of inflammation and then examined the diagnostic ability of combined SIRI and AFR values for serious early postoperative *** scored the patients and categorized them into three groups based on their SIRI and AFR *** analysis was used to compare the three groups of patients the prognostic value of various preoperative SIRI-AFR scores for 5-year overall survival(OS)and disease-free survival(DFS).RESULTS SIRI-AFR scores were an independent risk factor for prognosis[OS:P=0.004;hazards ratio(HR)=3.134;DFS:P<0.001;HR=3.543]and had the highest diagnostic power(area under the curve:0.779;95%confidence interval:0.737-0.820)for early serious complications in patients with gastric *** tumor-node-metastasis stage(P=0.001),perioperative transfusion(P=0.044),positive carcinoembryonic antigen(P=0.014)findings,and major postoperative complications(P=0.011)were factors associated with *** Preoperative SIRI and AFR values were s

关键词： Inflammation Albumin fibrinogen ratio Gastric cancer Complications Prognosis

Clinical characteristics of sudden hearing loss during pregnancy

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世界耳鼻咽喉头颈外科杂志英文版 2024年第3期10卷 165-172页

作者： Wu Xiao-Nan wang Hong-Yang Zhang Xiao-Long Chen Guo-Hui Guan Jing Gao Yun wang da-Yong wang Qiu-Ju Senior Department of Otolaryngology-Head & Neck Surgery The Sixth Medical Center of PLA General Hospital Chinese PLA Medical School Beijing China National Clinical Research Center for Otolaryngologic Diseases Beijing China

Objective: The objective of this study was to explore the clinical characteristics and management of sudden hearing loss (HL) during pregnancy, thus better guiding the clinical ***: The clinical and follow-up data of 17 patients (17 ears) with sudden HL during pregnancy were analyzed retrospectively (the observe group). Twelve nonpregnant female patients (12 ears) with sudden HL of similar clinical characteristics were selected as the control group. The prognosis of the two groups was compared. All the patients were followed up after delivery, and two of them were readmitted to the hospital 1–2 months after ***: The observe group had better improvement in hearing and a higher response rate compared to the control group. The pure tone hearing and speech recognition rate of patients could still be improved after the readmitted treatment, and the hearing could partially recover spontaneously during follow-up. The laboratory indicators that affect the inflammatory response and coagulation pathway were significantly different between the two ***: The hearing condition of sudden HL during pregnancy is severe, and the prognosis of these patients is better than nonpregnant patients of similar clinical characteristics. Postpartum treatment is still effective, and some patients showed self-healing with time during follow-up. The inflammatory response and coagulation function may affect the hearing of patients through a metabolic pathway.

关键词： management pregnancy prognosis sudden hearing loss

Micro-power negative pressure wound technique reduces risk of incision infection following loop ileostomy closure

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 186-195页

作者： Deng-Yong Xu Bing-Jun Bai Lina Shan Hui-Yan Wei Deng-Feng Lin Ya wang da wang Department of Colorectal Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina Department of Wound&Ostomy Care Clinic Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina Department of Hospital Infection Control Zhejiang Cancer HospitalHangzhou 310005Zhejiang ProvinceChina

BACKGROUND Prophylactic loop ileostomy is an effective way to reduce the clinical severity of anastomotic leakage following radical resection of rectal *** surgical site infection(SSI)is a common complication after ileostomy *** To evaluate the efficacy and safety of the micro-power negative pressure wound technique(MPNPWT)in preventing incisional *** This was a prospective,randomized controlled clinical trial conducted at a single center.A total of 101 consecutive patients who underwent ileostomy closure after rectal cancer surgery with a prophylactic ileostomy were enrolled from January 2019 to December *** were randomly allocated into an MPNPWT group and a control *** MPNPWT group underwent intermittent suturing of the surgical incision with 2-0 Prolene and was covered with a micro-power negative pressure *** surgical outcomes were compared between the MPNPWT(n=50)and control(n=51)*** factors for incisional SSI were identified using logistic *** There were no differences in baseline characteristics between the MPNPWT(n=50)and control groups(n=51).The incisional SSI rate was significantly higher in the control group than in the MPNPWT group(15.7%vs 2.0%,P=0.031).However,MPNPWT did not affect other surgical outcomes,including intra-abdominal complications,operative time,and blood *** hospital stay length and hospitalization costs did not differ significantly between the two groups(P=0.069 and 0.843,respectively).None of the patients experienced adverse effects of MPNPWT,including skin allergy,dermatitis,and *** also helped heal the infected *** study indicated that MPNPWT was an independent protective factor[odds ratio(OR)=0.005,P=0.025)]and diabetes was a risk factor(OR=26.575,P=0.029)for incisional *** MPNPWT is an effective and safe way to prevent incisional SSI after loop ileostomy closure.

关键词： Micro-power negative pressure technique Ileostomy closure Incisional surgical site infection Infection prevention Postoperative incision

Geochemical Anomalies Identified by Multifractal Modeling: Implications for Mineral Exploration in the Ziyoutun Cu-Au District, Jilin Province, China

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Acta Geologica Sinica(English Edition) 2024年第4期98卷 1111-1124页

作者： MA Huchao wang da BAI Feng LIU Meng GONG Anzhou HU Haiyan State Key Laboratory of Geological Processes and Mineral Resources School of Earth Sciences and ResourcesChina University of GeosciencesBeijing 100083China School of Gemmology China University of GeosciencesBeijing 100083China Guizhou Nengda Electric Power Design Co. Ltd.Guiyang 550002China Chongqing Chuandongnan Survey&Design Institute Co. Ltd.Chongqing 400038China

The Ziyoutun Cu-Au district is located in the Jizhong–Yanbian Metallogenic Belt and possesses excellent prospects. However, the thick regolith and complex tectonic settings present challenges in terms of detecting and decomposition of weak geochemical anomalies. To address this challenge, we initially conducted a comprehensive analysis of 1:10,000-scale soil geochemical data. This analysis included multivariate statistical techniques, such as correlation analysis, R-mode cluster analysis, Q–Q plots and factor analysis. Subsequently, we decomposed the geochemical anomalies, identifying weak anomalies using spectrum-area modeling and local singularity analysis. The results indicate that the assemblage of Au-Cu-Bi-As-Sb represents the mineralization at Ziyoutun. In comparison to conventional methods, spectrumarea modeling and local singularity analysis outperform in terms of identification of anomalies. Ultimately, we considered four specific target areas(AP01, AP02, AP03 and AP04) for future exploration, based on geochemical anomalies and favorable geological factors. Within AP01 and AP02, the geochemical anomalies suggest potential mineralization at depth, whereas in AP03 and AP04 the surface anomalies require additional geological investigation. Consequently, we recommend conducting drilling, following more extensive surface fieldwork, at the first two targets and verifying surface anomalies in the last two targets. We anticipate these findings will significantly enhance future exploration in Ziyoutun.

关键词： geochemical anomalies multivariate statistical analysis spectrum-area model local singularity analysis mineral prospecting Jilin Province

作业车间调度的拓扑排序及其在邻域解动态构造中的应用

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系统工程理论与实践 2024年第5期44卷 1680-1698页

作者：黄学文王达王强大连理工大学经济管理学院大连116024

在求解作业车间调度问题(job-shop scheduling problem, JSP)的局部搜索算法中,构造移动执行后的邻域解严重影响了局部搜索算法的计算效率.为此,基于拓扑排序和工序最大弧数的相关理论,提出了调度解拓扑排序的划分方法,实现了邻域解拓... 详细信息

在求解作业车间调度问题(job-shop scheduling problem, JSP)的局部搜索算法中,构造移动执行后的邻域解严重影响了局部搜索算法的计算效率.为此,基于拓扑排序和工序最大弧数的相关理论,提出了调度解拓扑排序的划分方法,实现了邻域解拓扑排序的构造;并在邻域解的拓扑排序中,准确地识别了邻域解中头和尾时间发生改变的工序集合,从而实现了邻域解的快速、动态构造.实验结果表明:相比于目前的邻域解构造方法,所提出的邻域解的动态构造方法,在计算速度上有着明显优势,且能够显著地节省计算时间.

关键词：动态构造邻域解拓扑排序作业车间调度邻域结构

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美元体系的边际调整及其对全球经济的冲击

马克思主义与现实 2024年第3期 165-173页

作者：王达吉林大学经济学院吉林大学美国研究所

近年来,美元体系的供给、流通、回流以及治理机制出现了紊乱甚至失能的现象。美国量化宽松货币政策失度加剧了“新特里芬两难”,应对乌克兰危机的失策削弱了“石油美元”体系,联邦政府债务失控侵蚀了美元体系的基石,金融监管失察加剧了... 详细信息

近年来,美元体系的供给、流通、回流以及治理机制出现了紊乱甚至失能的现象。美国量化宽松货币政策失度加剧了“新特里芬两难”,应对乌克兰危机的失策削弱了“石油美元”体系,联邦政府债务失控侵蚀了美元体系的基石,金融监管失察加剧了国际金融动荡,大国竞争战略失常则加速了去美元化进程。美元体系的边际调整具有必然性和长期性,美元体系有可能向失序、失能、失效的路径演进,全球经济则可能陷入金融风险、转型风险与政治风险相互交织的困境。广大发展中国家在短期内难以摆脱美国货币政策溢出效应的负面影响,其金融安全和可持续发展都面临前所未有的挑战。美元体系的边际调整是美国霸权式微的体现,其根源在于美国固守霸权思维、推卸国际责任、追求狭隘的安全和地缘政治利益以及缺乏大国应有的格局与气度。

关键词：美元体系边际调整 “新特里芬两难” 全球经济去美元化

Systemic inflammatory response index is a predictor of prognosis in gastric cancer patients: Retrospective cohort and meta-analysis

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 382-395页

作者： Jing-Yao Ren Meng Xu Xiang-Dong Niu Shi-Xun Ma Ya-Jun Jiao da wang Miao Yu Hui Cai School of Clinical Medicine Ningxia Medical UniversityYinchuan 750000Ningxia Hui autonomous regionChina Gansu Provincial Hospital Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina General Surgery Clinical Medical Center Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina Medical College of Jiangsu University Jiangsu UniversityZhenjiang 212013Jiangsu ProvinceChina Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

BACKGROUND The systemic inflammatory response index(SIRI)has been demonstrated to make a significant difference in assessing the prognosis of patients with different solid ***,research is needed to ascertain the accuracy and reliability of applying the SIRI to patients who undergo robotic radical gastric cancer *** To validate the applicability of the SIRI in assessing the survival of gastric cancer patients and evaluate the clinical contribution of preoperative SIRI levels to predicting long-term tumor outcomes in patients,who received robotic radical gastric cancer *** Initially,an exhaustive retrieval was performed in the PubMed,the Cochrane Library,EMBASE,Web of Science,and Scopus databases to identify relevant ***,a meta-analysis was executed on 6 cohort studies iden-tifying the value of the SIRI in assessing the survival of gastric cancer ***,the clinical data of 161 patients undergoing robotic radical gastric cancer surgery were retrospectively analyzed to evaluate their clinicopathological characteristics and relevant laboratory *** association between preoperative SIRI levels and 5-year overall survival(OS)and disease-free survival(DFS)was *** The findings demonstrated an extensive connection between SIRI values and the outcome of patients with gastric *** SIRI levels were identified as an independent hazard feature for both OS and DFS among those who received robotic surgery for gastric *** levels in gastric cancer patients were observed to be associated with the presence of comorbidities,T-stage,carcinoembryonic antigen levels,the development of early serious postoperative complications,and the rate of lymph node *** SIRI values are correlated with adverse in the gastric cancer population and have the potential to be utilized in predicting long-term oncological survival in patients who undergo robotic radical gastric canc

关键词： Systemic inflammatory response index Prognosis Gastric cancer Complications Meta-analysis