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Stepped-up development of accelerator mass spectrometry method for the detection of ^(60)Fe with the HI-13 tandem accelerator

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Nuclear Science and Techniques 2024年第4期35卷 136-143页

作者： Yang zhang Sheng-Quan Yan Ming he Qing-zhang Zhao Wen-Hui zhang Chao-Xin Kan Jian-Ming Zhou Kang-ning Li xiao-Fei wang Jian-cheng Liu Zhao-hua peng Zhuo Liang Ai-Ling Li Jian zheng Qi-Wen Fan yun-Ju Li You-Bao wang Zhi-Hong Li Yang-Ping Shen ding Nan Wei Nan Yu-Qiang zhang Jia-Ying-hao Li Jun-Wen Tian Jiang-Lin Hou Chang-Xin Guo Zhi-cheng zhang Ming-hao Zhu Yu-Wen Chen Yu-Chen Jiang Tao Tian jin-long ma Yi-Hui Liu jing-Yu Dong Run-long Liu Mei-yue-Nan ma Yong-Shou Chen Wei-Ping Liu Bing Guo China Institute of Atomic Energy P.O.Box 275(10)Beijing 102413China College of Science Southern University of Science and TechnologyShenzhen 518055China School of Physics Xi’an Jiaotong UniversityXi’an 710049China

The Moon provides a unique environment for investigating nearby astrophysical events such as *** samples retain valuable information from these events,via detectable long-lived“fingerprint”radionuclides such as^(60)*** this work,we stepped up the development of an accelerator mass spectrometry(AMS)method for detecting^(60)Fe using the HI-13tandem accelerator at the China Institute of Atomic Energy(CIAE).Since interferences could not be sufficiently removed solely with the existing magnetic systems of the tandem accelerator and the following Q3D magnetic spectrograph,a Wien filter with a maximum voltage of±60 kV and a maximum magnetic field of 0.3 T was installed after the accelerator magnetic systems to lower the detection background for the low abundance nuclide^(60)Fe.A 1μm thick Si_(3)N_(4) foil was installed in front of the Q3D as an energy *** particle detection,a multi-anode gas ionization chamber was mounted at the center of the focal plane of the ***,an^(60)Fe sample with an abundance of 1.125×10^(-10)was used to test the new AMS *** results indicate that^(60)Fe can be clearly distinguished from the isobar^(60)*** sensitivity was assessed to be better than 4.3×10^(-14)based on blank sample measurements lasting 5.8 h,and the sensitivity could,in principle,be expected to be approximately 2.5×10^(-15)when the data were accumulated for 100 h,which is feasible for future lunar sample measurements because the main contaminants were sufficiently separated.

关键词： Accelerator mass spectrometry Wien filter Isobar separation Supernovae Chang'e-5 lunar samples

Efficacy and safety of sirolimus early conversion protocol in liver transplant patients with hepatocellular carcinoma:A single-arm, multicenter, prospective study

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hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 106-112页

作者： Ren-Yi Su Sun-Bin Ling Qiao-Nan Shan Xu-Yong Wei Rui wang Chang-Ku Jia Li Zhuang Tian Shen Li-Min ding Zhi-Dan Xu Lai-Bang Luo Li-Bo Sun Guang-Ming Li Tai-Shi Fang Nan Jiang Kun zhang Zhao-Jie Su Zhi-Hai peng Ren Lang Tao Jiang Qiang he Lin-Sen Ye Yang Yang Yu-Ting he Wen-Zhi Guo Liu-Gen Lan Xu-Yong Sun Dong Chen Zhi-Shui Chen Da-Wei Zhou Shao-Jun Ye Qi-Fa Ye Min Tian Jian-hua Shi Bo wang Jiang Liu Qian Lu Wei Rao jin-Zhen Cai Tao Lv Jia-Yin Yang Pu-Sen wang Lin Zhong jing-Sheng ma Qi-Gen Li Sheng-Dong Wu Chang-Jiang Lu Cai-De Lu Dong-hua zhang Xuan wang Zi-Qiang Li Mu-Jian Teng Jun-Jie Li Wen-Tao Jiang Jian-hua Li Quan-Bao zhang ning-Qi Zhu zheng-Xin wang Kang he Qiang Xia Shao-hua Song Zhi-Ren Fu Wei Qiu Guo-yue Lv Rui-peng Song Ji-Zhou wang zheng wang Jian Zhou Gang Chen Ying-peng Zhao Li Li Ze-Min Hu Qi-Jie Luo Zhong-Zhou Si Bin Xie xiao-Shun he Zhi-Yong Guo Shu-Sen zheng xiao Xu Department of hepatobiliary and Pancreatic Surgery The Center for Integrated Oncology and Precision MedicineAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 310003China Department of hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhou 310022China Department of hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Transplantation Jiangxi Provincial People’s Hospital Affiliated to Nanchang UniversityNanchang 330006China Liver Transplantation Center Beijing You’an HospitalCapital Medical UniversityBeijing 100069China Department of hepatic Surgery National Clinical Research Center for Infectious DiseaseShenzhen Third People’s HospitalThe Second Affiliated Hospital of Southern University of Science and TechnologyShenzhen 518112China Department of General Surgery Xiang’an Hospital of Xiamen UniversityXiamen 361000China Deartment of hepatobiliary and Pancreaticosplenic Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Department of hepatic Surgery and Liver Transplantation Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630China Department of hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Liver Transplantation The Second Affiliated Hospital of Guangxi Medical UniversityNanning 530000China Institute of Organ Transplantation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Institute of hepatobiliary Diseases of Wuhan University Transplant Center of Wuhan UniversityHubei Key Laboratory of Medical Technology on TransplantationZhongnan Hospital of Wuhan UniversityWuhan 430071China Department of hepatobiliary Surgery The First Affiliated Hos

mammalian target of rapamycin(m TOR) inhibitor as an attractive drug target with promising antitumor effects has been widely investigated. High quality clinical trial has been conducted in liver transplant(LT) recipients in Western countries. However, the pertinent studies in Eastern world are paucity. Therefore, we designed a clinical trial to test whether sirolimus can improve recurrence-free survival(RFS) in hepatocellular carcinoma(HCC) patients beyond the Milan criteria after LT. This is an open-labeled, single-arm, prospective, multicenter, and real-world study aiming to evaluate the clinical outcomes of early switch to sirolimus-based regimens in HCC patients after LT. Patients with a histologically proven HCC and beyond the Milan criteria will be enrolled. The initial immunosuppressant regimens are center-specifc for the frst 4-6 weeks. The following regimens integrated sirolimus into the regimens as a combination therapy with reduced calcineurin inhibitors based on the condition of patients and centers. The study is planned for 4 years in total with a 2-year enrollment period and a 2-year follow-up. We predict that sirolimus conversion regimen will provide survival benefts for patients particular in the key indicator RFS as well as better quality of life. If the trial is conducted successfully, we will have a continued monitoring over a longer follow-up time to estimate indicator of overall survival. We hope that the outcome will provide better evidence for clinical decision-making and revising treatment guidelines based on Chinese population data.

关键词： Sirolimus Immunosuppressive agents hepatocellular carcinoma Liver transplantation Conversion

Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano max Buesken mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera hao Cai xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna jinfan Chang yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen zhang Chen Jie cheng Yaping cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering marco Diaz xuefeng ding Yayun ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini martin Dvorak Timo Enqvist heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-cheng feng Qichun feng Richard Ford Andrey Formozov Amélie Fournier haonan Gan feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin marco Grassi Christian Grewing maxim Gromov Vasily Gromov Minghao Gu xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone maria Gul Cong Guo jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yan Yerevan Physics Institute YerevanArmenia UniversitéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina chongqing University ChongqingChina Dongguan University of Technology DongguanChina jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Department of Physics National T

The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main *** of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator *** this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approximately 60,000 signal and 30,000 background events are *** large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith ***,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment.

关键词： neutrino oscillation solar neutrino JUNO

Sub-percent precision measurement of neutrino oscillation parameters with JUNO

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Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde marcondes de André Didier Auguste Weidong Bai Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga hao Cai xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Chi Chan jinfan Chang yun Chang Guoming Chen Pingping Chen Po-An Chen Shaomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie cheng Yaping cheng Yu Chin cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering marco Diaz xuefeng ding Yayun ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng Dong Evgeny Doroshkevich marcos Dracos Frédéric Druillole Ran Du Shuxian Du Stefano Dusini martin Dvorak Timo Enqvist heike Enzmann Andrea Fabbri Donghua Fan Lei Fan Jian Fang Wenxing Fang marco Fargetta Dmitry Fedoseev zhengyong Fei Li-cheng feng Qichun feng Richard Ford Amélie Fournier haonan Gan feng Gao Alberto Garfagnini Arsenii Gavrikov marco Giammarchi Nunzio Giudice maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Alexandre Göttel marco Grassi Vasily Gromov Minghao Gu xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao he Wei he Tobias heinz Patrick hellmuth yuekun heng Rafael herrera yuenKeung Ho Yerevan Physics Institute YerevanArmenia UniversiéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina chongqing University ChongqingChina Dongguan University of Technology DongguanChina jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observatory under construction in the south of *** publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the *** sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite *** is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data *** the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering *** new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO

“中国心血管病人生活质量评定问卷”常模的测定(英文)

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心血管康复医学杂志 2010年第6期19卷 569-574页

作者：刘江生马琛明涂良珍王瑛郑伯仁王福军洪华山郭兰殷兆芳李鹏虹郑茵翁向群张勇杨胜利李莉林明魁丁家崇郭克峰刘青山任爱华唐海沁巢毅郑直翁志远刘建李筱雯林金先戴若竹 Publishing House Chinese Journal of Cardiovascular Rehabilitative MedicineFuzhou Department of Cardiology Anzhen Hospital of Beijing Department of Cadres People's Hospital of Xinjiang Uygur Autonomous Region Department of Cardiology Central Hospital of Changchun City Department of Cardiology Second Hospital of Fuzhou City Department of Cardiology The People's Hospital of Xianxi Autonomous Region of Hunan Department of Cadres Affiliated Union Hospital of Fujian Medical University Region of Cardiac Rehabilitation Guangdong Province Institute of Cardiovascular Diseases Department of Cardiology Ninth People's Hospital of Shanghai City Geriatric Hospital of Fujian Province Center of Rehabilitation People's Hospital of Hainan Province VIP Department Fuzhou General HospitalNanjing Military Command of PLA Department of Cardiology Geriatric Hospital of Hainan Province Department of Cardiology General Hospital of Armed Police Forces Cardiac Center Chuiyangliu Hospital of Beijing People's Hospital of Nanping City of Fujian Department of Cardiology Mawangdui Hospital of Hunan Province Department of Rehabilitation Tangdu Hospital of Xian Department of Cardiology Affiliated Hospital of Xianan College of Hunan Rehabilitative Center of Cardiovascular Diseases Zhejiang Hospital Department of Cardiology First Affiliated Hospital of Anhui Medical University Second Hospital of Nanping City of Fujian Department of Cardiology People's Hospital of Fujian Province Department of Cardiology Central Hospital of Jiamusi city of Heilongjiang First Affiliated Hospital of Kunming Medical College of yunan Province Institute of Sports Medicine Third Hospital of Beijing University Boai Hospital of longyan city Fujian Province Department of Cardiology First Hospital of Quanzhou cityFujian Province

目的：就高血压、冠心病、充血性心力衰竭（CHF）患者测定＂中国心血管病人生活质量评定问卷＂（CQQC）的常模,并分析其影响因素。方法：采用整群随机抽样的方法,对地跨中国各大区的19个城市28所医院的7937名对象的生活质量进行调查,建... 详细信息

目的：就高血压、冠心病、充血性心力衰竭（CHF）患者测定＂中国心血管病人生活质量评定问卷＂（CQQC）的常模,并分析其影响因素。方法：采用整群随机抽样的方法,对地跨中国各大区的19个城市28所医院的7937名对象的生活质量进行调查,建立全国常模,并比较性别、年龄、运动、心理状态、教育、家庭以及医疗条件所致的差异。结果：1、正常人平均得分（国家常模）为（95.74±23.21）分;2、高血压患者平均得分为（73.75±23.62）,高血压3级患者生活质量（69.06±21.78）明显低于其他患者（P〈0.01）;3、冠心病患者的平均得分为（64.67±20.59）,其中不稳定型心绞痛患者的生活质量（55.37±18.62）最差（P〈0.01）;4、CHF患者的平均得分为（40.36±17.24）,显著低于高血压和冠心病患者（P〈0.01）;5、影响因素：（1）性别、年龄：所有人的总体得分为（71.41±27.8）分,男性得分非常显著高于女性（P=0.000）;正常人随着年龄增加,得分逐渐减少（P〈0.05）,除≥70岁组,其他各年龄组男性得分显著高于女性得分（P〈0.05）;（2）运动：参加运动者的得分（72.64±21.87）非常显著高于未参加运动者（66.91±23.13）,P=0.000;（3）心理：心理健康者的得分（70.13±25.66）非常显著高于心理有障碍者（68.91±20.44）,P=0.001;（4）其他：受教育程度越高,得分越高;家庭成员为1个人的得分明显低于2人组和3人及以上组的得分;自费患者的得分低于医保或公费患者的得分（P〈0.05~〈0.001）。结论：本研究样本量大,数据可靠;中国心血管病人生活质量评定问卷能反映年龄、性别、运动、心理、家庭、受教育程度、医疗条件和疾病对生活质量的影响,条目简短明了,可操作性好,值得推广。

关键词：心血管疾病康复生活质量

“中国心血管病人生活质量评定问卷”常模的测定

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心血管康复医学杂志 2009年第4期18卷 305-309页

作者：刘江生马琛明涂良珍王瑛郑伯仁王福军洪华山郭兰殷兆芳李鹏虹郑茵翁向群张勇杨胜利李莉林明魁丁家崇郭克峰刘青山任爱华唐海沁巢毅郑直翁志远刘建李筱雯心血管康复医学杂志社福建福州350003 北京安贞医院心内科新疆维吾尔自治区人民医院干部科长春市中心医院心内科福州市第二医院心内科湖南湘西土家族苗族自治州人民医院心内科福建医科大学附属协和医院干部病房广东省心血管病研究所心脏康复区上海市第九人民医院心内科福建省老年医院海南省人民医院医疗康复中心南京军区福州总医院侨宾科海南省老年病医院心内科武警总医院心内科北京市垂杨柳医院心脏中心福建省南平市人民医院湖南省马王堆医院心内科西安唐都医院康复科湘南学院附属医院心内科浙江医院心血管病康复中心安徽医科大学第一附属医院心内科福建省南平市第二医院福建省人民医院心内科黑龙江省佳木斯市中心医院心内科昆明医学院第一附属医院北京大学第三医院运动医学研究所

目的:就高血压、冠心病、充血性心力衰竭(CHF)测定"中国心血管病人生活质量评定问卷"(CQQC)的常模,并分析其影响因素。方法:采用整群随机抽样的方法,对地跨全国各大区的20个城市28所医院的7937名对象的生活质量进行调查,建立全国常模,... 详细信息

目的:就高血压、冠心病、充血性心力衰竭(CHF)测定"中国心血管病人生活质量评定问卷"(CQQC)的常模,并分析其影响因素。方法:采用整群随机抽样的方法,对地跨全国各大区的20个城市28所医院的7937名对象的生活质量进行调查,建立全国常模,并比较性别、年龄、运动、心理状态、教育、家庭以及医疗条件所致的差异。结果:(1)正常人平均得分(常模)为(95.74±23.21)分;(2)高血压患者平均得分为(73.75±23.62),高血压III期患者生活质量(69.06±21.78)明显低于其他患者(P<0.01);(3)冠心病患者的平均得分为(64.67±20.59),其中不稳定型心绞痛患者的生活质量(55.37±18.62)最差(P<0.01);(4)CHF患者的的平均得分为(40.36±17.24),显著低于高血压和和冠心病患者(P<0.01);(5)影响因素:①性别、年龄:所有人的总体得分为(71.41±27.8)分,男性得分非常显著高于女性(P=0.000);正常人随着年龄增加,得分逐渐减少(P<0.05),除≥70岁组,其他各年龄组男性得分显著高于女性得分(P<0.05);②运动:参加运动者的得分(72.64±21.87)非常显著高于未参加运动者(66.91±23.13),P=0.000;③心理:心理健康者的得分(70.13±25.66)非常显著高于心理有障碍者(68.91±20.44),P=0.001;④其他:受教育程度越高,得分越高;家庭成员为1个人的得分明显低于2人组和3人及以上组的得分;自费患者的得分低于医保或公费患者的得分(P<0.05～<0.001)。结论:本研究样本量大,数据可靠;中国心血管病人生活质量评定问卷能反映年龄、性别、运动、心理、家庭、受教育程度、医疗条件和疾病对生活质量的影响,条目简短明了,可操作性好,值得推广。

关键词：心血管疾病康复生活质量

新冠肺炎疫情期间医疗机构不同区域工作岗位个人防护专家共识

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中国感染控制杂志 2020年第3期19卷 199-213页

作者：李春辉黄勋蔡虻陈萍陈文森陈修文邓子德董宏亮付强高武强高晓东龚瑞娥巩玉秀侯铁英胡国庆胡必杰李洁李卫光林玲刘丁刘聚源刘卫平刘运喜陆群马红秋茅一萍孟秀娟逄崇杰乔甫任南单淑娟孙树梅汤灵玲童德军王辉王力红王庆红文建国吴红曼吴红梅吴静吴秀颖鲜于舒铭向天新熊薇徐艳阎颖杨怀杨亚红姚希袁晓宁岳丽青曾翠曾烂漫张浩军张静萍张乐张卫红张永栋周鹏程宗志勇左双燕李六亿吴安华无中南大学湘雅医院全国医院感染监控管理培训基地国家老年疾病临床医学研究中心(湘雅) 湖南长沙410008 北京医院北京100730 成都市公共卫生临床医疗中心四川成都610000 江苏省人民医院南京医科大学第一附属医院江苏南京210029 江西省儿童医院江西南昌330006 中山大学附属第三医院广东广州510630 西安市第九医院陕西西安710054 国家医院感染管理专业质控中心北京100191 复旦大学附属中山医院上海200032 国家卫生健康委离退局北京100044 广东省人民医院广东广州510080 浙江省疾病预防控制中心浙江杭州310051 山东省立医院山东济南250021 黑龙江疾病预防控制中心黑龙江哈尔滨150000 陆军特色医学中心重庆400042 内蒙古自治区人民医院内蒙古呼和浩特010010 解放军总医院北京100039 浙江大学医学院附属第二医院浙江杭州310009 安徽医科大学第一附属医院安徽合肥230022 徐州医科大学附属医院江苏徐州221006 天津医科大学总医院天津300052 四川大学华西医院四川成都610041 南方医科大学南方医院广东广州510515 浙江树人大学树兰(杭州)医院浙江杭州310000 中南大学湘雅二医院湖南长沙410011 北京大学人民医院北京100044 首都医科大学宣武医院北京100053 新乡医学院第一附属医院河南新乡453100 温州市人民医院浙江温州325000 海南省人民医院海南海口570311 南昌大学第一附属医院江西南昌330006 华中科技大学同济医学院附属同济医院湖北武汉430030 贵州省人民医院贵州贵阳550002 郑州人民医院河南郑州450003 甘肃省人民医院甘肃兰州730000 北京大学第一医院北京100034 北京大学第三医院北京100191 中国医科大学附属第一医院辽宁沈阳110001 青海大学附属医院青海西宁810001 中华预防医学会医院感染控制分会中国医院协会医院感染管理专业委员会中国感染控制杂志编辑委员会

为更好地防控新型冠状病毒(2019-nCoV)医院感染,保障医疗机构医务人员及其他工作人员的安全,合理使用个人防护用品,中华预防医学会医院感染控制分会、中国医院协会医院感染管理专业委员会、中国感染控制杂志编辑委员会组织国内专家(包... 详细信息

为更好地防控新型冠状病毒(2019-nCoV)医院感染,保障医疗机构医务人员及其他工作人员的安全,合理使用个人防护用品,中华预防医学会医院感染控制分会、中国医院协会医院感染管理专业委员会、中国感染控制杂志编辑委员会组织国内专家(包括赴武汉抗疫一线的部分专家)共同制定本共识。本共识主要适用于同时收治新冠肺炎患者和普通患者的医疗机构;指导疫情期间医疗机构一线医务人员合理有效利用防护用品,同时也覆盖了几乎所有非一线医务人员及其他工作人员的防护用品使用。本共识通过评估医疗机构工作人员新冠肺炎暴露的风险,根据暴露风险来确定不同区域不同岗位工作人员的个人防护标准。本共识主要内容还包括:个人防护用品介绍及适用范围,三级防护穿脱流程,个人防护用品异常的防范与应急处理,新型冠状病毒肺炎职业暴露处置流程。同时,本共识特别强调,要合理进行新冠疫情期间医疗机构区域划分,以及重点分诊岗位安排有经验的感染科或呼吸科医生参与分诊,这些是风险评估的前提要求;在选择个人防护用品时,既要防止防护不足,又要避免滥用与过度使用,以保障工作人员安全为前提,预防新冠肺炎医院感染。

关键词：新型冠状病毒新型冠状病毒肺炎 2019-nCoV COVID-19 个人防护用品区域岗位分级防护共识

JUNO sensitivity on proton decay p→νK^(+)searches

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Chinese Physics C 2023年第11期47卷 7-22页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram 安丰鹏安琪 Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde marcondes de André Didier Auguste Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga 蔡浩蔡啸蔡严克蔡志岩 Riccardo Callegari Antonio Cammi Agustin Campeny 曹传亚曹国富曹俊 Rossella Caruso Cédric Cerna 常劲帆 yun Chang 陈平平 Po-An Chen 陈少敏陈旭荣 Yi-Wen Chen 陈义学陈羽陈长程捷程雅苹 Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille 邓智邓子艳 Wilfried Depnering marco Diaz xuefeng ding 丁雅韵 Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko 董建蒙 Evgeny Doroshkevich marcos Dracos Frédéric Druillole 杜然杜书先 Stefano Dusini martin Dvorak Timo Enqvist heike Enzmann Andrea Fabbri Ulrike Fahrendholz 范东华樊磊方建方文兴 marco Fargetta Dmitry Fedoseev Li-cheng feng 冯启春 Richard Ford Amélie Fournier 甘浩男 feng Gao Alberto Garfagnini Arsenii Gavrikov marco Giammarchi Agnese Giaz Nunzio Giudice maxim Gonchar 龚光华宫辉 Yuri Gornushkin Alexandre Göttel marco Grassi Christian Grewing Vasily Gromov 顾旻皓谷肖飞古宇关梦云 Nunzio Guardone maria Gul 郭聪郭竞渊郭万磊郭新恒郭宇航 Paul Hackspacher Caren Hagner 韩然 Yang Han Muhammad Sohaib Hassan 何苗何伟 Tobias heinz Patrick hellmuth 衡月昆 Rafael herrera 贺远强侯少静 Yee Hsiung Bei-Zhen Hu 胡航胡健润胡俊胡守扬胡涛胡宇翔胡焯钧黄春豪黄桂鸿黄翰雄黄文昊黄鑫黄性涛黄永波惠加琪霍雷霍文驹 Cédric Huss Safeer Hussain Ara Ioannisian Roberto Isocrate Beatrice Jelmini Kuo-Lun Jen Ignacio Jeria 季筱璐吉星曌贾慧慧贾俊基蹇司玉蒋荻蒋炜江晓山金如意荆小平 Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Ka Pontificia Universidad Católica de Chile SantiagoChile IPHC Universitéde StrasbourgCNRS/IN2P3F-67037 StrasbourgFrance Pakistan Institute of Nuclear Science and Technology IslamabadPakistan INFN Catania and Dipartimento di Fisica e Astronomia dell Universitàdi Catania CataniaItaly East China University of Science and Technology ShanghaiChina University of Science and Technology of China HefeiChina Joint Institute for Nuclear Research DubnaRussia INFN Sezione di Milano and Dipartimento di Fisica dell Universitàdi Milano MilanoItaly Department of Physics Faculty of ScienceChulalongkorn UniversityBangkokThailand IJCLab UniversitéParis-SaclayCNRS/IN2P391405 OrsayFrance Department of Physics and Earth Science University of Ferrara and INFN Sezione di FerraraFerraraItaly INFN Milano Bicocca and University of Milano Bicocca MilanoItaly INFN Sezione di Padova PadovaItaly III.Physikalisches Institut B RWTH Aachen UniversityAachenGermany Eberhard Karls Universität Tübingen Physikalisches InstitutTübingenGermany Institute of High Energy Physics BeijingChina SUBATECH Universitéde NantesIMT AtlantiqueCNRS-IN2P3NantesFrance Univ.Bordeaux CNRSLP2IUMR 5797F-33170 GradignanFrance Department of Physics National Taiwan UniversityTaipei Dipartimento di Fisica e Astronomia dell’Universitàdi Padova and INFN Sezione di Padova PadovaItaly University of Roma Tre and INFN Sezione Roma Tre RomaItaly Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance Wuhan University WuhanChina INFN Milano Bicocca and Politecnico of Milano MilanoItaly National United University Miao-Li Dongguan University of Technology DongguanChina Tsinghua University BeijingChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Institute of Physics National Yang Ming Chiao Tung UniversityHsinchu North China Electric Power University BeijingChina Sun Yat-Sen University GuangzhouChina Beijing Institute of Spacecraft Environment Engineering BeijingChina Universidade Estadual de Londrina LondrinaBrazil INFN Sez

The Jiangmen Underground Neutrino Observatory(JUNO)is a large liquid scintillator detector designed to explore many topics in fundamental *** this study,the potential of searching for proton decay in the p→νK^(+)mode with JUNO is *** kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for ***,the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed *** on these advantages,the detection efficiency for the proton decay via p→νK^(+)is 36.9%±4.9%with a background level of 0.2±0.05(syst)±0.2(stat)events after 10 years of data *** estimated sensitivity based on 200 kton-years of exposure is 9.6×1033 years,which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies.

关键词： proton decay grand unified theories JUNO liquid scintillator detector