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Impacts of Soil Moisture on the Numerical Simulation of a Post-Landfall Storm

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Journal of Meteorological Research 2019年第2期33卷 206-218页

作者： Feimin ZHANG Zhaoxia PU chenghai wang College of Atmospheric Sciences Lanzhou University Department of Atmospheric Sciences University of Utah

Surface heat and moisture fluxes are important to the evolution of a tropical storm after its landfall. Soil moisture is one of the essential components that influence surface heating and moisture fluxes. In this study, the impact of soil moisture on a pre-landfall numerical simulation of Tropical Storm Bill(2015), which had a much longer lifespan over land, is investigated by using the research version of the NCEP Hurricane Weather Research and Forecasting(HWRF) model. It is found that increased soil moisture with SLAB scheme before storm's landfall tends to produce a weaker storm after landfall and has negative impacts on storm track simulation. Further diagnoses with different land surface schemes and sensitivity experiments indicate that the increase in soil moisture inside the storm corresponds to a strengthened vertical mixing within the storm boundary layer, which is conducive to the decay of storm and has negative impacts on storm evolution. In addition, surface diabatic heating effects over the storm environment are also found to be an important positive contribution to the storm evolution over land, but their impacts are not so substantial as boundary layer vertical mixing inside the storm. The overall results highlight the importance and uncertainty of soil moisture in numerical model simulations of landfalling hurricanes and their further evolution over land.

关键词： soil moisture tropical storm tropical cyclone landfall la nd surface numerical simulation

Oscillation propagation features of the atmosphere around the Qinghai-Xizang Plateau during the spring season of typical strong and weak monsoon years

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Science China Earth Sciences 2011年第2期54卷 305-314页

作者： wang chenghai CUI Yang JIN ShuangLong Key Laboratory for Semi-Arid Climate Change of the Ministry of Education College of Atmospheric Sciences Lanzhou University Lanzhou 730000 China National Climate Center China Meteorological Administration Beijing 100081 China

The interaction between the low-frequency atmospheric oscillation(Madden-Julian Oscillation,MJO) and the diabatic heating over the Qinghai-Xizang Plateau(QXP) from March to June is *** results show that there are respectively two and one wave trains around the QXP during the onset of the South China Sea monsoon in strong and weak monsoon *** locations and strength of the wave train propagation differ between the strong and weak monsoon *** diabatic heating of the QXP prevents the low-frequency oscillation,the wave train of interaction between the diabatic heating and the zonal wind MJO propagates along the west and east of the QXP in the strong monsoon *** distribution of the wave train interaction between the diabatic heating and the zonal wind MJO traverses the QXP and coincides with the location of the southern and northern upper-level jet streams,showing that they are remarkably *** interesting and notable phenomenon is that the interaction between diabatic heating and the zonal wind MJO over the QXP suddenly disappears during the monsoon onset in weak monsoon years.

关键词： Madden-Julian oscillation South China Sea monsoon diabatic heating Qinghai-Xizang Plateau

hsa_circ_0013058促进食管鳞状细胞癌侵袭和迁移的机制研究

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实用临床医药杂志 2024年第7期28卷 29-35页

作者：谈艳陶菲儿王成海扬州大学医学院病理学教研室江苏扬州225009 江苏省扬州洪泉医院放疗中心江苏扬州225200 江苏省中西医结合老年病防治重点实验室江苏扬州225001

目的探讨食管鳞状细胞癌(ESCC)中hsa_circ_0013058的作用及其促进ESCC细胞侵袭和迁移的机制。方法收集75例患者的ESCC组织及癌旁正常组织。采用实时荧光定量聚合酶链反应(qRT-PCR)和RNA原位杂交技术(RISH)检测hsa_circ_0013058表达情况... 详细信息

目的探讨食管鳞状细胞癌(ESCC)中hsa_circ_0013058的作用及其促进ESCC细胞侵袭和迁移的机制。方法收集75例患者的ESCC组织及癌旁正常组织。采用实时荧光定量聚合酶链反应(qRT-PCR)和RNA原位杂交技术(RISH)检测hsa_circ_0013058表达情况,并分析其与ESCC患者临床病理资料的关系。采用划痕实验和Transwell实验检测ESCC细胞侵袭和迁移能力。采用生物信息学方法预测hsa_circ_0013058的靶基因。采用Rescue实验检测hsa_circ_0013058对下游基因的调控及对ESCC细胞侵袭、迁移的影响。结果qRT-PCR结果显示,ESCC组织中hsa_circ_0013058表达量高于癌旁正常组织,差异有统计学意义(t=5.078,P<0.05)。ESCC细胞株KYSE70中hsa_circ_0013058表达量高于人正常食管上皮细胞Het-1A,差异有统计学意义(P<0.05)。在RNA水平上,hsa_circ_0013058与miR-548p呈负相关(r=-0.2542,P<0.05)。ESCC组织中,hsa_circ_0013058 RNA阳性表达率为72.00%,高于癌旁正常组织的17.33%,差异有统计学意义(χ2=6.862,P<0.05)。hsa_circ_0013058阳性表达与肿瘤浸润深度、分化程度和淋巴结转移均密切相关(P<0.05)。划痕实验结果表明,过表达hsa_circ_0013058增强KYSE70细胞的迁移能力(P<0.05);敲低hsa_circ_0013058表达减弱KYSE70细胞的迁移能力(P<0.05)。过表达hsa_circ_0013058后,ESCC细胞侵袭和迁移细胞数目增加,敲低hsa_circ_0013058表达后,侵袭和迁移细胞数目下降(P<0.05)。qRT-PCR实验证实,hsa_circ_0013058可调控微小RNA-548p(miR-548p)表达。双荧光素酶报告基因实验表明,miR-548p与LPAR3为特异性结合,LPAR3是miR-548p的直接靶基因。Rescue实验结果表明,hsa_circ_0013058通过miR-548p/LPAR3信号轴调控ESCC细胞的侵袭、转移。结论ESCC中,hsa_circ_0013058抑制miR-548p表达,进而激活LPAR3信号通路,促进ESCC细胞的侵袭、迁移。

关键词：食管鳞状细胞癌 hsa_circ_0013058 微小RNA-548p LPAR3基因侵袭迁移

Evaluation of the WRF-Lake Model over Two Major Freshwater Lakes in China

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Journal of Meteorological Research 2019年第2期33卷 219-235页

作者： Yuanyuan MA Yi YANG Chongjian QIU chenghai wang Key Laboratory for Semi-Arid Climate Change of the Ministry of Education College of Atmospheric SciencesLanzhou University Key Laboratory of Land Surface Process and Climate Change in Cold and Arid Regions Northwest Institute of Eco-Environment and Resources Chinese Academy of Sciences

This paper evaluates the performance of the Weather Research and Forecasting(WRF) model coupled with a lake scheme over the Lake Poyang and Lake Dongting regions. We choose several cases with different weather characteristics, including winter with/without precipitation and summer with/without precipitation, and conduct a series of experiments(without the lake model, with the default lake model, and with a calibrated lake model that adjusts the water absorption, extinction coefficients, and surface roughness length) for each case. The results show that the performance of the lake model is significantly affected by the weather conditions. For the winter with precipitation cases, the performance of the default lake model is even worse than without the lake model, but the calibrated lake model can obviously reduce the biases of 2-m temperature and dew-point temperature. Although the performance of the default and new calibrated models is intricate for other cases, the new calibrated model has prominent advantages for 2-m dew-point temperature. Moreover, a long-term simulation of five months also shows that the new calibrated coupled lake model performs better than the default one. These imply that the new calibrated coupled lake model is more suitable to be used in studies of the effects of Lake Poyang and Lake Dongting on regional weather and climate.

关键词： atmosphere-lake coupled model Lake Poyang Lake Dongting calibration weather characteristics

Properties of Cloud and Precipitation over the Tibetan Plateau

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Advances in Atmospheric Sciences 2015年第11期32卷 1504-1516页

作者： wang chenghai SHI Hongxia HU Haolin wang Yi XI Baike Key Laboratory of Arid Climate Change and Disaster Reduction of Gansu Province College of Atmospheric SciencesLanzhou University Troop 93212 The People's Liberation Army Department of Atmospheric Sciences University of North Dakota4149 University Ave.

The characteristics of seasonal precipitation over the Tibetan Plateau （TP） were investigated using TRMM （Tropical Rain- fall Measuring Mission） precipitation data （3B43）. Sensitive regions of summer precipitation interannual variation anomalies were investigated using EOF （empirical orthogonal function） analysis. Furthermore, the profiles of cloud water content （CWC） and precipitable water in different regions and seasons were analyzed using TRMM-3A12 data observed by the TRMM Microwave Imager. Good agreement was found between hydrometeors and precipitation over the eastern and southeastern TP, where water vapor is adequate, while the water vapor amount is not significant over the western and northern TE Further analysis showed meridional and zonal anomalies of CWC centers in the ascending branch of the Hadley and Walker Circulation, especially over the south and east of the TE The interannual variation of hydrometeors over the past decade showed a decrease over the southeastern and northwestern TP, along with a corresponding increase over other regions.

关键词： cloud liquid water content cloud ice water content precipitable liquid water Tibetan Plateau

结直肠腺癌组织中tiRNA-1_33-Gly-GCC-1的表达及临床意义

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现代肿瘤医学 2024年第6期32卷 1075-1083页

作者：翟晨王会月严雪冰王成海扬州大学医学院病理教研室江苏扬州225009 丹阳市第三人民医院消化科江苏镇江212300 扬州大学附属医院肿瘤科江苏扬州225009

目的:研究结直肠腺癌(colorectal adenocarcinoma,CAC)组织中tiRNA-1_33-Gly-GCC-1的表达及对细胞增殖的影响。方法:通过tRF&tiRNA芯片分析5对CAC组织中tRFs&tiRNAs差异性表达谱并用qRT-PCR实验在82对CAC组织中对tiRNA-1_33-Gly-GCC-1的表达水平进行验证。采用RNA原位杂交技术(RISH)检测CAC组织中tiRNA-1_33-Gly-GCC-1的阳性表达,并分析与患者临床特征和患者预后的关系。CCK-8实验检测tiRNA-1_33-Gly-GCC-1对细胞增殖活性的影响。生物信息学预测并应用双荧光素酶报告实验验证tiRNA-1_33-Gly-GCC-1如何调控TP53I11。回复实验验证tiRNA-1_33-Gly-GCC-1/TP53I11信号轴对CAC细胞增殖的影响。裸鼠荷瘤实验验证tiRNA-1_33-Gly-GCC-1对移植瘤生长和增殖的影响。结果:tiRNA-1_33-Gly-GCC-1在结直肠腺癌组织中表达水平升高并呈阳性表达,阳性例数54/82(65.85%)明显高于邻近正常组织11/82(13.41%),两组间有统计学差异(χ^(2)=5.475,P=0.019<0.05)。tiRNA-1_33-Gly-GCC-1的阳性表达与CAC患者肿瘤直径(χ^(2)=11.699)、分化程度(χ^(2)=13.081)和患者生存预后(χ^(2)=15.621)密切相关(均P<0.05)。CCK-8实验结果显示tiRNA-1_33-Gly-GCC-1促进CAC细胞的增殖活性(P<0.05)。生物信息学预测TP53I11是tiRNA-1_33-Gly-GCC-1的下游靶基因,双荧光素酶报告基因实验提示tiRNA-1_33-Gly-GCC-1与TP53I113'UTR结合从而抑制其蛋白质合成。Rescue回复实验进一步验证了tiRNA-1_33-Gly-GCC-1抑制TP53I11 mRNA和蛋白的表达及对大肠癌细胞增殖的促进作用。裸鼠皮下移植瘤实验也提示tiRNA-1_33-Gly-GCC-1促进了生长和增殖。结论:tiRNA-1_33-Gly-GCC-1在结直肠腺癌组织中表达水平上调,可能是一个新的促癌基因;机制上tiRNA-1_33-Gly-GCC-1能抑制TP53I11的表达而促进CAC细胞的增殖生长。本研究为今后结直肠腺癌诊治和预后判断提供新的理论基础。

关键词：结直肠腺癌 tiRNA-1_33-Gly-GCC-1 TP53I11 细胞增殖

Evidence for a recent warming and wetting in the source area of the Yellow River （SAYR） and its hydrological impacts

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Journal of Geographical Sciences 2015年第6期25卷 643-668页

作者： TIAN Hui LAN Yongchao WEN Jun JIN Huijun wang chenghai wang Xin KANG Yue Key Laboratory of Land Surface Process and Climate Change in Cold and Arid Regions CAS Lanzhou 730000 China College of Atmospheric Sciences Lanzhou University Lanzhou 730000 China

Climate change investigation at a watershed-scale plays a significant role in re- vealing the historical evolution and future trend of the runoff variation in watershed. This study examines the multisource hydrological and meteorological variables over the source area of the Yellow River （SAYR） from 1961 to 2,012 and the future climate scenarios in the region during 2006-2100 based on the CMIP5 projection data. It recognizes the significant charac-teristics of the recent climate change in the SAYR and predicts the change trend of future flow in the region. It is found that （1） The climate in the SAYR has experienced a significant warm-wet change since the early 2000s, which is very different from the antecedent warm-dry trend since the late 1980s; （2） The warm-wet trend in the northwestern SAYR （the headwater area of the Yellow River （HAYR）, is more obvious than that in the whole SAYR; （3） With pre- cipitation increase, the runoff in the region also experienced an increasing process since 2006. The runoff variations in the region are sensitive to the changes of precipitation, PET and maximum air temperature, but not very sensitive to changes in mean and minimum air temperatures; （4） Based on the CMIP5 projection data, the warm-wet climate trend in SAYR are likely to continue until 2049 if considering three different （i.e. RCP2.6, RCP4.5 and RCP8.5） greenhouse gas emission scenarios, and the precipitation in SAYR will not be less than the current level before 2100; however, it is estimated that the recent flow increase in the SAYR is likely to be the decadal change and it will at most continue until the 2020s; （5） The inter-annual variations of the East Asian winter monsoon are found to be closely related to the variations of annual precipitation in the region. Meanwhile, the increased precipitation as well as the increase of potential evapotranspiration （PET） being far less than that of precipitation in the recent period are the main climate causes for the flow incr

关键词： source area of the Yellow River (SAYR) climate warming and wetting decadal scale hydrological impacts

过去40 a来祁连山地区植被变化特征及其与气候的关系

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干旱气象 2024年第3期42卷 385-394页

作者：杨斐冯祥张飞民王澄海甘肃省气候资源开发及防灾减灾重点实验室兰州大学大气科学学院甘肃兰州730000 甘肃省生态环境科学设计研究院甘肃兰州730000

在全球变暖背景下,祁连山植被生长状态发生了明显变化,研究祁连山植被与气候的关系对西北地区生态建设具有重要意义。基于1982—2022年GIMMS NDVI数据及ERA5气温和降水数据,分析祁连山地区NDVI的变化趋势及其与气候因子的相关性。结果表... 详细信息

在全球变暖背景下,祁连山植被生长状态发生了明显变化,研究祁连山植被与气候的关系对西北地区生态建设具有重要意义。基于1982—2022年GIMMS NDVI数据及ERA5气温和降水数据,分析祁连山地区NDVI的变化趋势及其与气候因子的相关性。结果表明,祁连山地区NDVI高值区主要集中在东段(0.6~0.8),并自东向西逐渐减小。过去40 a,祁连山地区NDVI整体呈增加趋势,主要由于生长季NDVI的显著增加,而在非生长季,祁连山中、东部部分地区NDVI呈减小趋势。祁连山地区NDVI的变化与气温、降水整体呈正相关关系,但生长季NDVI与降水在祁连山东部部分地区呈负相关,非生长季NDVI与气温在祁连山西部部分地区呈负相关。祁连山夏季NDVI与对应时段气温和降水之间存在显著耦合模态,气温和降水的增加整体上对NDVI增加有益,但祁连山东部地区生长季NDVI增加主要由气温升高所致。

关键词：植被 NDVI 气候变化耦合模态祁连山

Recent Progress in Studies of the Variabilities and Mechanisms of the East Asian Monsoon in a Changing Climate

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Advances in Atmospheric Sciences 2019年第9期36卷 887-901页

作者： Wen CHEN Lin wang Juan FENG Zhiping WEN Tiaojiao MA Xiuqun YANG chenghai wang Center for Monsoon System Research Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China Department of Atmospheric and Oceanic Sciences Fudan UniversityShanghai 200438China School of Atmospheric Sciences Nanjing UniversityNanjing 210023China College of Atmospheric Sciences Lanzhou UniversityLanzhou 730000China

Located in a monsoon domain,East Asia suffers devastating natural hazards induced by anomalous monsoon *** Asian monsoon(EAM)research has traditionally been a high priority for the Chinese climate community and is particularly challenging in a changing climate where the global mean temperature has been *** advances in studies of the variabilities and mechanisms of the EAM are reviewed in this paper,focusing on the interannual to interdecadal time *** new results have been achieved in understanding the behaviors of the EAM,such as the evolution of the East Asian summer monsoon(EASM),including both its onset and withdrawal over the South China Sea,the changes in the northern boundary activity of the EASM,or the transitional climate zone in East Asia,and the cycle of the EASM and the East Asian winter monsoon and their *** addition,understanding of the mechanism of the EAM variability has improved in several aspects,including the impacts of different types of ENSO on the EAM,the impacts from the Indian Ocean and Atlantic Ocean,and the roles of mid-to high-latitude ***,some scientific issues regarding our understanding of the EAM are proposed for future investigation.

关键词： East Asian summer monsoon East Asian winter monsoon changing climate monsoon onset and withdrawal transitional climate zone different types of ENSO