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Resilience and response:Unveiling the impacts of extreme droughts on forests through integrated dendrochronological and remote sensing analyses

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Forest Ecosystems 2024年第4期11卷 491-501页

作者： Han Shi Xi Peng Yong-Jiao Zhou ai-ying wang Xue-Kai Sun Na Li Quan-Sheng Bao Gude Buri Guang-You Hao CAS Key Laboratory of Forest Ecology and Silviculture Institute of Applied EcologyChinese Academy of SciencesShenyang110016China Daqinggou Ecological Research Station Institute of Applied EcologyChinese Academy of SciencesShenyang110016China University of Chinese Academy of Sciences Beijing100049China School of Life Science and Engineering Shenyang UniversityShenyang110044China Wudantala Forestry Forestry and Grassland Administration of Horqin Northeast CountyTongliao028100China

Extreme droughts are anticipated to have detrimental impacts on forest ecosystems,especially in water-limited regions,due to the influence of climate ***,considerable uncertainty remains regarding the patterns in species-specific responses to extreme ***,we conducted a study integrating dendrochronology and remote sensing methods to investigate the mosaic-distributed maple-oak(native)natural forests and poplar plantations(introduced)in the Horqin Sandy Land,Northeast *** assessed the impacts of extreme droughts on tree performances by measuring interannual variations in radial growth and vegetation *** results showed that precipitation and self-calibrated palmer drought severity index(scPDSI)are the major factors influencing tree-ring width index(RWI)and normalized difference vegetation index(NDVI).The severe droughts between 2000 and 2004 resulted in reduced RWI in the three studied tree species as well as led to NDVI reductions in both the maple-oak natural forests and the poplar *** RWI reached the nadir during the2000-2004 severe droughts and remained at low levels two years after the severe drought,creating a legacy *** contrast to the lack of significant correlation between RWI and scPDSI,NDVI exhibited a significant positive correlation with scPDSI indicating the greater sensitivity of canopy performance to droughts than radial ***,interspecific differences in RWI and NDVI responses were observed,with the fast-growing poplar species experiencing a more significant RWI decrease and more negative NDVI anomaly during severe droughts than native species,highlighting the species-specific trade-offs between drought resilience and growth *** study emphasizes the importance of combining tree-level radial growth with landscape-scale canopy remote sensing to understand forest resilience and *** study improves our understanding of forest responses to extreme drought and highlights species di

关键词： Introduced tree species Native tree species NDVI Severe drought Tree-ring width

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Decellularised extracellular matrix-based injectable hydrogels for tissue engineering applications

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Biomaterials Translational 2024年第2期5卷 114-128页

作者： Wan-ying Guo Wei-Huang wang Pei-Yao Xu Ranjith Kumar Kankala ai-Zheng Chen Institute of Biomaterials and Tissue Engineering Huaqiao UniversityXiamenFujian ProvinceChina Fujian Provincial Key Laboratory of Biochemical Technology(Huaqiao University) XiamenFujian ProvinceChina

Decellularised extracellular matrix(dECM)is a biomaterial derived from natural tissues that has attracted considerable attention from tissue engineering researchers due to its exceptional biocompatibility and malleability *** advantageous properties often facilitate natural cell infiltration and tissue reconstruction for regenerative *** to their excellent fluidity,the injectable hydrogels can be administered in a liquid state and subsequently formed into a gel state in vivo,stabilising the target area and serving in a variety of ways,such as support,repair,and drug release ***,dECM-based injectable hydrogels have broad prospects for application in complex organ structures and various tissue injury *** review focuses on exploring research advances in dECM-based injectable hydrogels,primarily focusing on the applications and prospects of dECM hydrogels in tissue ***,the recent developments of the dECM-based injectable hydrogels are explained,summarising the different preparation methods with the evaluation of injectable hydrogel ***,some specific examples of the applicability of dECM-based injectable hydrogels are ***,we summarise the article with interesting prospects and challenges of dECM-based injectable hydrogels,providing insights into the development of these composites in tissue engineering and regenerative medicine.

关键词： decellularisation methods decellularised extracellular matrix injectable hydrogels tissue engineering

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Epigenetic silencing schlafen-11 sensitizes esophageal cancer to ATM inhibitor

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2060-2073页

作者： Jing Zhou Mei-ying Zhang ai-ai Gao Cheng Zhu Tao He James G Herman Ming-Zhou Guo School of Medicine NanKai UniversityTianjin 300071China Department of Gastroenterology and Hepatology The First Medical CenterChinese PLA General HospitalBeijing 100853China Departments of Pathology Characteristic Medical Center of The Chinese People’s Armed Police ForceTianjin 300162China The Hillman Cancer Center University of Pittsburgh Cancer InstitutePittsburghPA 15213United States National Key Laboratory of Kidney Diseases Chinese PLA General HospitalBeijing 100853China

BACKGROUND Targeting DNA damage response(DDR)pathway is a cutting-edge *** has been reported that Schlafen-11(SLFN11)contributes to increase chemosensitivity by participating in ***,the detailed mechanism is *** To investigate the role of SLFN11 in DDR and the application of synthetic lethal in esophageal cancer with SLFN11 *** To reach the purpose,eight esophageal squamous carcinoma cell lines,142 esophageal dysplasia(ED)and 1007 primary esophageal squamous cell carcinoma(ESCC)samples and various techniques were utilized,including methylationspecific polymerase chain reaction,CRISPR/Cas9 technique,Western blot,colony formation assay,and xenograft mouse *** Methylation of SLFN11 was exhibited in 9.15%of(13/142)ED and 25.62%of primary(258/1007)ESCC cases,and its expression was regulated by promoter region ***11 methylation was significantly associated with tumor differentiation and tumor size(both P<0.05).However,no significant associations were observed between promoter region methylation and age,gender,smoking,alcohol consumption,TNM stage,or lymph node *** DNA damaged model induced by low dose cisplatin,SLFN11 was found to activate non-homologous end-joining and ATR/CHK1 signaling pathways,while inhibiting the ATM/CHK2 signaling *** silencing of SLFN11 was found to sensitize the ESCC cells to ATM inhibitor(AZD0156),both in vitro and in *** SLFN11 is frequently methylated in human *** of SLFN11 is sensitive marker of ATM inhibitor in ESCC.

关键词： Schlafen-11 Esophageal squamous cell carcinoma DNA methylation Synthetic lethality AZD0156

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变迁之神:白帝天王信仰流变与湘西社会

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中南民族大学学报（人文社会科学版） 2007年第5期27卷 71-74页

作者：王爱英武警广州指挥学院训练部广东广州510440

白帝天王信仰在湘西特定的社会历史文化背景下形成,同时又以无处不在的"灵力"影响着湘西大地。致力于湘西开发的历代统治者也对之表现了极大的关注,特别是"乾嘉苗民起义"以来,其"显灵助战"的记载屡屡见诸史籍并得以跻身国家祀典,国家和... 详细信息

白帝天王信仰在湘西特定的社会历史文化背景下形成,同时又以无处不在的"灵力"影响着湘西大地。致力于湘西开发的历代统治者也对之表现了极大的关注,特别是"乾嘉苗民起义"以来,其"显灵助战"的记载屡屡见诸史籍并得以跻身国家祀典,国家和地方社会在文化资源上的共享和互动进一步加强。

关键词：湘西白帝天王信仰流变社会变迁

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Artificial Intelligence and Network Pharmacology Reveal the Medication Rules of Professor wang Yu-ying in the Treatment of Climacteric Syndrome

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World Journal of Traditional Chinese Medicine 2024年第2期10卷 180-190页

作者： Meng-Yuan Hu Tian-Xing Yi Qi-Rui Liu Xin-Yu Zhang ai-Ping Chen Yu-ying wang Yi Lu School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijingChina

Objective: The objective of this study was to explore the medication rules and academic ideas of Professor wang Yu-ying in the treatment of climacteric syndrome(CLS) and to predict new prescriptions. Materials and Methods: The characteristics of frequency, clustering, four properties, and five flavors were analyzed, and new prescriptions were predicted through an artificial intelligence(ai)-based method. The potential pathways of new prescriptions were explored through network pharmacology-based analysis. Results: The top 16 medicinals used by Professor wang Yu-ying in the treatment of CLS included Danggui, Longgu, Muli, Fuling, Chuanxiong, Gancao, Xiangfu, and Tusizi. The ai method was applied to predict the basic prescription for treating CLS: Danggui 15 g, Duanlonggu 30 g, Duanmuli 30 g, Fuling 28 g, Chuanxiong 10 g, Gancao 6 g, Xiangfu 12 g, Tusizi 14 g, etc., Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses showed that the pathogenesis of CLS might be related to the estrogen pathway, involving typical steroid responses. Conclusions: This study summarized Professor wang's medication experience in the treatment of CLS based on the data mining of clinical diagnoses and treatment cases. The ai method was used to predict the new prescription of CLS treatment, which was found to be reasonable by network pharmacology studies on its multi-target and multi-pathway mechanisms.

关键词： Artificial intelligence climacteric syndrome medication rules network pharmacology Professor wang Yu-ying

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Research on Risk Identification and Industrial Governance of Digital Education Products Based on Data Annotation Technology

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China Communications 2024年第3期21卷 273-282页

作者： Tong Lili Zeng Jia Di ying wang Nan Faculty of Education Beijing Normal University Beijing 100875China China Unicom Beijing 102211China

The social transformation brought aboutby digital technology is deeply impacting various *** education products, with core technologiessuch as 5G, ai, IoT (Internet of Things),etc., are continuously penetrating areas such as teaching,management, and evaluation. Apps, miniprograms,and emerging large-scale models are providingexcellent knowledge performance and flexiblecross-media output. However, they also exposerisks such as content discrimination and algorithmcommercialization. This paper conducts anevidence-based analysis of digital education productrisks from four dimensions: “digital resourcesinformationdissemination-algorithm design-cognitiveassessment”. It breaks through corresponding identificationtechnologies and, relying on the diverse characteristicsof governance systems, explores governancestrategies for digital education products from the threedomains of “regulators-developers-users”.

关键词： digital education products industry governance risk identification

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不同厚度四面体非晶碳薄膜的高通量制备及表征

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无机材料学报 2018年第11期33卷 1173-1178页

作者：魏菁李汉超柯培玲汪爱英中国科学院宁波材料技术与工程研究所中国科学院海洋新材料与应用技术重点实验室浙江省海洋材料与防护技术重点实验室宁波315201 中国科学院大学北京100049 上海科技大学物质科学与技术学院上海201210

材料基因组工程能大幅度提高材料研发速度,降低材料研发成本,近年来受到广泛关注。本研究采用高通量制备工艺,结合碳等离子体束流和基片位置的调控,利用自主设计研制的45°双弯曲磁过滤阴极真空电弧设备,沉积了厚度为4.7～183 nm的系列... 详细信息

材料基因组工程能大幅度提高材料研发速度,降低材料研发成本,近年来受到广泛关注。本研究采用高通量制备工艺,结合碳等离子体束流和基片位置的调控,利用自主设计研制的45°双弯曲磁过滤阴极真空电弧设备,沉积了厚度为4.7～183 nm的系列四面体非晶碳(ta-C)薄膜,使用椭偏仪、原子力显微镜、拉曼光谱仪和X射线光电子能谱仪(XPS)表征了厚度对ta-C薄膜表面粗糙度、微结构和原子键态的影响。结果表明:通过碳等离子体束流和基片位置的调控,实现了不同厚度ta-C薄膜的高通量制备。尽管膜厚不同,所制备的ta-C薄膜均具有几乎不变的光滑表面(R_a=(0.38±0.02) nm)和色散值(Disp(G)),说明不同厚度ta-C薄膜的sp^3含量、sp^2团簇尺寸保持相对稳定。XPS结果进一步证实ta-C薄膜的sp3相对含量均维持在(55±5)%。此外,不同厚度ta-C薄膜的光学带隙E_(opt)均保持在(1.02±0.08)eV。相关结果为设计制备结构和光学性能可控的不同厚度ta-C薄膜提供了一种新思路。

关键词：四面体非晶碳膜高通量厚度微结构光学带隙

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新疆天然光照度变化趋势分析

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干旱区研究 2014年第2期31卷 261-266页

作者：何荥全利王爱英重庆大学建筑城规学院山地城镇建设与新技术教育部重点实验室重庆400045 重庆建筑工程职业学院建筑经济系重庆400039 天津大学建筑学院天津300072

基于新疆8个城市连续50 a(1961—2010年)的太阳辐射及气象数据,结合中国辐射光当量模型,获取各城市天然光年总照度值。应用Mann-Kendall检验方法,分析各城市天然光年总照度变化趋势及年际变化趋势。结果表明:年总照度变化幅度最大的城... 详细信息

基于新疆8个城市连续50 a(1961—2010年)的太阳辐射及气象数据,结合中国辐射光当量模型,获取各城市天然光年总照度值。应用Mann-Kendall检验方法,分析各城市天然光年总照度变化趋势及年际变化趋势。结果表明:年总照度变化幅度最大的城市为喀什,其年总照度降低2.4×108lx·(10a)-1;年总照度变化幅度最小的城市为若羌,其年总照度降低1.1×108lx·(10a)-1。城市年总照度年际变化趋势为喀什逐年递减;阿勒泰、乌鲁木齐、伊宁、哈密、吐鲁番及和田为先波动后下降,且下降趋势显著,若羌为先波动后下降,但下降趋势不显著。

关键词：关键词太阳辐射辐射光当量天然光照度 Mann—Kendall法新疆

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绿色照明产品评价方法

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重庆建筑大学学报 2000年第3期22卷 7-11页

作者：陈仲林王爱英重庆建筑大学建筑城规学院重庆400045

从绿色设计出发 ,根据生命周期评价方法和层次分析法。

关键词：绿色照明层次分析法评价方法

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一氧化氮供体化合物的合成方法研究进展

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有机化学 2017年第4期37卷 777-797页

作者：王兵李娜刘腾王英爱王晓静孙捷济南大学山东省医学科学院医学与生命科学学院济南250200 山东省医学科学院药物研究所国家卫生部生物技术药物重点实验室山东省罕少见病重点实验室济南250062

一氧化氮(NO)作为生物信使或效应分子在体内发挥重要的生理作用,因其具有多种多样的生物活性在临床应用方面得到广泛关注.体内NO生成不足常与多种疾病的形成密切相关,NO供体化合物可以通过在体内释放NO治疗和预防多种疾病.随着NO供体化... 详细信息

一氧化氮(NO)作为生物信使或效应分子在体内发挥重要的生理作用,因其具有多种多样的生物活性在临床应用方面得到广泛关注.体内NO生成不足常与多种疾病的形成密切相关,NO供体化合物可以通过在体内释放NO治疗和预防多种疾病.随着NO供体化合物的广泛应用,其合成方法引起了国内外研究人员的高度重视.结合国内外学者对这方面的研究,对近10年NO供体化合物的合成方法研究进展进行综述.

关键词：一氧化氮供体合成方法药理活性

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