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嵌入式电容层析成像系统的成像加速方法研究

西安交通大学学报 2024年第3期58卷 183-192页

作者：陆程程胡红利唐凯豪单宇杰黄敬轩董海健西安交通大学电力设备电气绝缘国家重点实验室西安710049 四川大学电气工程学院成都610065 西安西电电力电容器有限责任公司西安710082

为了提高嵌入式系统设计中电容层析成像(ECT)的图像重构速度,研究了一种针对进阶精简指令集机器加上现场可编程门阵列(ARM+FPGA)硬件架构的图像重构算法加速技术。针对广泛应用且鲁棒的Landweber迭代算法(ILA),首先分析算法结构,然后基... 详细信息

为了提高嵌入式系统设计中电容层析成像(ECT)的图像重构速度,研究了一种针对进阶精简指令集机器加上现场可编程门阵列(ARM+FPGA)硬件架构的图像重构算法加速技术。针对广泛应用且鲁棒的Landweber迭代算法(ILA),首先分析算法结构,然后基于FPGA的流水线特点,改进ILA涉及的循环结构,从而达到加速的效果。同时,针对ARM+FPGA架构的特点,讨论了ARM核与FPGA核各自的任务分配方式,进一步优化了算法速度。为了验证算法的有效性,分别在使用MATLAB编程和使用提出的加速方法搭建的ZYNQ平台进行了图像重构实验,从图像重构耗时、图像相对误差和图像相关系数3个指标论证提出方法的有效性。实验结果显示,使用搭建的ZYNQ平台进行Landweber算法成像时,每个图像的运行时间比使用MATLAB编程的运行时间减少了30%~40%。该研究在保持重构精度的同时有效提升了迭代算法的速度,对于ECT系统的硬件加速具有一定适用性。

关键词：电容层析成像图像重构算法硬件加速嵌入式系统

pH响应型磁性纳米复合材料的合成及其载药性能

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应用化学 2024年第6期41卷 861-869页

作者：王灵晓高杉韦皖豫李宁波乔洁董川太原工业学院化学化工系太原030008 山西医科大学基础医学院太原030001 山西大学环境科学研究所太原030006

采用改进的Stöber法制备了介孔硅包覆的磁性纳米材料,然后通过枝接的方法对材料表面进行了氨基化处理(NH_(2)-MMNPs)。利用安全无毒的氧化普鲁兰作为门控材料,通过纳米材料表面的氨基与氧化普鲁兰的醛基之间形成的对酸敏感的亚胺键构建... 详细信息

采用改进的Stöber法制备了介孔硅包覆的磁性纳米材料,然后通过枝接的方法对材料表面进行了氨基化处理(NH_(2)-MMNPs)。利用安全无毒的氧化普鲁兰作为门控材料,通过纳米材料表面的氨基与氧化普鲁兰的醛基之间形成的对酸敏感的亚胺键构建门控开关,并将负载的盐酸阿霉素封装,形成了智能给药系统(oMMNPs/DOX)。通过透射电子显微镜(SEM)、傅里叶变换红外光谱仪(FT-IR)、比表面积测试仪、X射线衍射仪(XRD)和振动样品磁强仪等技术手段对复合材料的结构、性能和形貌进行了表征。结果显示,复合材料具有良好的形貌、单分散性以及超顺磁性。载药和释药实验表明,NH_(2)-MMNPs对阿霉素的载药率为51.65%;oMMNPs/DOX在药物释放过程中表现出pH响应性和药物缓释性。细胞毒性和荧光成像实验结果显示,复合材料具有良好的生物兼容性,能够成功地载药并被细胞摄取。

关键词：氧化普鲁兰磁性纳米粒子介孔硅 pH响应阿霉素

Intensive peatland wildfires during the Aptian-Albian oceanic anoxic event 1b:Evidence from borehole SK-2 in the Songliao Basin,NE China

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Journal of Palaeogeography 2022年第3期11卷 448-467页

作者： Zhi-Hui Zhang Da-Wei Lü Tian-Tian wang dong-Zhao An Hai-Yan Liu dong-dong wang Cheng-shan wang shandong Provincial Key Laboratory of Depositional Mineralization and Sedimentary Minerals College of Earth Sciences and EngineeringShandong University of Science and TechnologyQingdao 266590Shandong ProvinceChina Institute of Earth Sciences China University of GeosciencesBeijing 100083China School of Earth Sciences and Resources China University of GeosciencesBeijing 100083China Chinese Academy of Geological Sciences Beijing 100037China

The Cretaceous has been considered a“high-fire”world accompanied by widespread by-products of combustion in the rock *** mid-Cretaceous oceanic anoxic event 1b(OAE1b)is marked by one of the major perturbations in the global carbon cycle characterized by deposition of organic-rich sediments in both marine and terrestrial ***,our understanding is still limited on changes in wildfire activity during OAE1b ***,we carried out a comprehensive analysis,including organic carbon isotope(δ^(13)C_(org)),total organic carbon(TOC),coal petrology,trace elements,and pyrolytic polycyclic aromatic hydrocarbons(pyroPAHs),of coal seams of the middle Aptian to early Albian Shahezi Formation from borehole SK-2 in Songliao Basin,Northeast *** negativeδ^(13)C_(org) excursions in the Shahezi Formation can be corresponded with the 113/Jacob and Kilian sub-events of ***,the intensive peatland wildfires have been identified during the sub-event periods of OAE1b based on the co-occurrence of high abundance of charcoal and pyroPAHs at that *** addition,Sr/Ba,Sr/Cu and Sr/Rb ratios demonstrate that enhanced peatland wildfires were controlled by dryer climate conditions owing to episodic northward migration of arid zones in East Asia related with rising global temperature during the sub-events of *** climate-driven extensive wildfire activity in the mid-latitude terrestrial ecosystems can be a contributing factor for OAE1b through the increased flux of nutrients fuelling primary producers in the lake and marine environments and leading to more speculative anoxia to allow the deposition of organic-rich *** results provide essential understanding of the importance of wildfires in driving mechanism of oceanic anoxic events(OAEs)in Earth's history.

关键词： Lower Cretaceous OAEs Peatland Wildfire Coals

超高效液相色谱-串联质谱法测定膏霜乳类化妆品中法定标准以外的48种糖皮质激素

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分析测试学报 2024年第7期43卷 978-986页

作者：沈丹丹宫珊珊李悦忱薛恒跃于本涛姜博海王冬张蓉毛希琴大连市药品检验检测院辽宁大连116021 大连理工大学化工学院辽宁大连116024

我国现行法定标准检验方法包括GB/T 24800.2-2009、GB/T 40145-2021和《化妆品安全技术规范》(2015年版),共涵盖58种糖皮质激素。该文以超高效液相色谱-串联质谱法测定膏霜乳类化妆品中法定标准以外的48种糖皮质激素。样品经提取、净化... 详细信息

我国现行法定标准检验方法包括GB/T 24800.2-2009、GB/T 40145-2021和《化妆品安全技术规范》(2015年版),共涵盖58种糖皮质激素。该文以超高效液相色谱-串联质谱法测定膏霜乳类化妆品中法定标准以外的48种糖皮质激素。样品经提取、净化后,通过Waters ACQUITY UPLC BEH C_(18)(3.0 mm×150 mm,1.7μm)色谱柱分离,以0.2%乙酸水溶液-0.2%乙酸甲醇溶液为流动相梯度洗脱。在电喷雾正离子模式下,以动态多反应监测(MRM)方式测定,外标法定量。48种糖皮质激素在2.5~60μg/L范围内具有良好的线性关系,相关系数均大于0.995,方法检出限(S/N≥3)和定量下限(S/N≥10)分别为0.03μg/g和0.1μg/g。所有目标物在膏霜乳基质中的基质效应不明显。在1倍、2倍和8倍定量下限加标水平下,平均回收率为80.9%~110%,相对标准偏差(RSD,n=6)为0.70%~9.3%。采用该方法在1份样品中检出6β-羟基曲安奈德,含量为0.3μg/g,并以多反应监测-信息依赖采集-增强子离子扫描模式(MRM-IDA-EPI)进行确证。该方法前处理操作简便可行、测定结果准确可靠,可填补化妆品中糖皮质激素的监管空白。

关键词：超高效液相色谱-串联质谱糖皮质激素化妆品非法添加

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Architecture,Key Technologies and Applications of Load Dispatching in China Power Grid

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Journal of Modern Power Systems and Clean Energy 2022年第2期10卷 316-327页

作者： Yu dong Xin shan Yaqin Yan Xiwu Leng Yi wang State Grid Corporation of China Beijing 100031China NARI Group Corporation(State Grid Electric Power Research Institute) Nanjing 211000China

With the development of renewable energy and the changes in the characteristics of power grid,it is becoming increasingly difficult to balance power supply and demand in space and *** addition,the requirement for improved dispatching capability of power grid is ***,the potential of flexible load dispatching should be realized,which can promote the large-scale consumption of renewable energy and the construction of new power *** on the analysis of existing load dispatching studies and the differences in the characteristics of domestic and foreign load dispatchings,a technical architecture and several key technologies are proposed for load resources to participate in power grid dispatching under the new situation,i.e.,the autonomous collaborative control system of load *** system implements the multi-layer coordinated control of main,distribution and micro grids(load aggregators).Adjustable load resources are aggregated through an aggregator operation platform and connected with a dispatcher load regulator platform to realize real-time data interaction with dispatching agencies as well as the monitoring,con-trol,and marketing of *** supports the load resources to participate in network-wide dispatching optimization via continuous power *** key technologies such as the control mode,load modeling,dispatching strategy,and safety protection are also *** the closed-loop control of orderly charging piles and energy storage clusters in the North China Power Grid,the feasibility of the proposed architecture and key technologies is *** route has successively supported multiple adjustable load aggregators to partici-pate in the ancillary services market of North China Power Grid for ***,the technical challenges of load resources participating in power grid dispatching under the dual carbon goals are discussed and prospected.

关键词： Automatic power control(APC) load modeling load dispatching renewable energy accommodation situation awareness.

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旋毛虫粪口传播途径的研究

中国人兽共患病学报 2024年第6期40卷 544-547,563页

作者：尹雪宇张珊珊张莉李海龙董玲大理大学基础医学院大理671000 云南省滇西抗病原植物资源筛选研究重点实验室大理671000

目的了解旋毛虫粪口传播途径的可行性及粪便中旋毛虫幼虫的感染力。方法试验将6只Wistar大鼠分别一次性感染4000条旋毛虫幼虫,于0、4、8、12、16、24和48 h收集3只大鼠(A组)粪便,分别分成4份于室温下保存0、24、48和72 h,显微镜下计数... 详细信息

目的了解旋毛虫粪口传播途径的可行性及粪便中旋毛虫幼虫的感染力。方法试验将6只Wistar大鼠分别一次性感染4000条旋毛虫幼虫,于0、4、8、12、16、24和48 h收集3只大鼠(A组)粪便,分别分成4份于室温下保存0、24、48和72 h,显微镜下计数粪便中幼虫数量,将每份含有旋毛虫幼虫的粪便喂给5只昆明小鼠,42 d后处死小鼠,计数幼虫数并计算生殖力指数(RCI);另外3只大鼠(B组)在感染后1~23 d收集粪便,提取DNA,通过PCR扩增旋毛虫线粒体atp6基因。结果A组大鼠感染旋毛虫幼虫后4~16 h排出幼虫,8 h排虫量达高峰,24 h及以后粪便中无旋毛虫幼虫。大鼠感染4、8、12、16 h后粪便中旋毛虫幼虫总数分别为350、400、145、40条。感染后4 h收集的大鼠粪便室温保存0、24、48 h后RCI分别为112.5、20.5、2;8 h收集的大鼠粪便室温保存0 h、24 h后RCI为66.7、9;12 h采集的大鼠粪便室温保存0和24 h后RCI为13.3和5;16 h收集的大鼠粪便室温保存0 h后RCI为10。B组大鼠中2只连续18 d扩增出旋毛虫线粒体atp6基因,1只连续20 d扩增出旋毛虫线粒体atp6基因。结论一次性大量食入旋毛虫幼虫后,可排出具有感染力的旋毛虫幼虫,可通过粪口途径进行传播。PCR可以检测粪便中的旋毛虫线粒体atp6基因,但不能确定旋毛虫是否具有感染力。

关键词：旋毛虫粪口途径传播感染力 atp6

Sleep disturbances and psychomotor retardation in the prediction of cognitive impairments in patients with major depressive disorder

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World Journal of Psychiatry 2024年第10期14卷 1474-1483页

作者： Mi wang Wen-Tao Chen Hao-Ting wang Bang-shan Liu Yu-Meng Ju Qiang-Li dong Xiao-Wen Lu Jin-Rong Sun Liang Zhang Hua Guo Fu-Tao Zhao Wei-Hui Li Li Zhang Ze-Xuan Li Mei Liao Yan Zhang Jin Liu Ling-Jiang Li Department of Mental Health Center Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina National Clinical Research Center of Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina Department of Psychiatry National Clinical Research Center for Mental DisordersThe Second Xiangya Hospital of Central South UniversityChangsha 410011Hunan ProvinceChina Department of Psychiatry Zhumadian Psychiatric HospitalZhumadian 463000Henan ProvinceChina

BACKGROUND Symptoms of depression and comorbid anxiety are known risk factors for cognitive impairment in major depressive disorder(MDD).Understanding their relationships is crucial for developing targeted interventions to mitigate cognitive impairments in MDD *** expect that the severity of sleep disturbances and other depressive symptoms will be positively correlated with the degree of cognitive *** also hypothesize that anxiety symptoms,especially psychic anxiety,is a key factor in predicting cognitive performance in MDD patients and may indirectly contribute to cognitive impairment by affecting sleep disturbances and other potential *** To determine which dimension of the depressive and anxiety symptoms predicts cognitive impairment during a depressive *** A comprehensive neurocognitive test battery assessed executive function,attention,processing speed,and memory in 162 medication-free MDD patients and 142 matched healthy *** 24-item Hamilton Depression Rating Scale was used to assess depressive symptoms,and the 14-item Hamilton Anxiety Scale was used to assess anxiety *** regression analyses and mediation analyses were conducted to evaluate the impact of depressive and anxiety symptoms,as well as their interactions,on cognitive *** Among the depressive symptoms,sleep disturbances were associated with poorer executive function(P=0.004),lower processing speed(P=0.047),and memory impairments(P<0.001),and psychomotor retardation(PR)was associated with lower processing speed in patients with MDD(P=0.019).Notably,PR was found to mediate the impact of sleep disturbances on the processing *** anxiety symptoms,psychic anxiety,rather than somatic anxiety,was associated with cognitive impairments in all *** disturbances mediated the effect of psychic anxiety on executive function[β=-0.013,BC CI(-0.027,-0.001)]and memory[β=-0.149,BC CI(-0.237,-0.063)],while PR mediated its ef

关键词： Major depressive disorder Cognitive impairment Depressive symptoms Anxiety symptoms Sleep disturbance Psychomotor retardation

临江高承压水砂层超深地连墙泥浆参数试验研究

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科学技术与工程 2024年第15期24卷 6405-6414页

作者：金明张旭晖陕耀董雅丞南京地铁建设有限责任公司南京210017 同济大学交通运输工程学院上海201804

南京地铁4号线二期工程滨江站—龙江区间中段江心洲风井工程地表存在淤泥质黏土和较厚高承压水粉砂层,下部覆盖高强度砂砾岩层,地连墙施工时若泥浆参数选择不当则难以起到护壁效果进而发生塌孔或缩孔情况。提高泥浆重度是增大槽壁稳定... 详细信息

南京地铁4号线二期工程滨江站—龙江区间中段江心洲风井工程地表存在淤泥质黏土和较厚高承压水粉砂层,下部覆盖高强度砂砾岩层,地连墙施工时若泥浆参数选择不当则难以起到护壁效果进而发生塌孔或缩孔情况。提高泥浆重度是增大槽壁稳定性安全系数的最直接方式,但同时也会增加工程成本。为探明淤泥覆盖下高承压水砂层中地连墙成槽作业时最优的泥浆参数,分析并评价该地质条件下的成槽质量,采用泥浆护壁的抛物柱法三维模型对泥浆参数进行计算,并通过试成槽试验和超声波检测对计算结果进行验证,最终选择出合适的泥浆配比。研究结果证明泥浆黏度为60 s,泥浆比重为1.07 g/cm^(3)时可以保证成槽稳定性系数为1.5,结果可为类似工程提供参考。

关键词：地下连续墙成槽试验三维破坏模型泥浆参数超声波检测

功能MRI探索2型糖尿病神经血管耦联改变机制进展

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中国医学影像技术 2024年第1期40卷 125-129页

作者：杨东许珊汪旭洋都丽娜林琳沈晶伍建林大连大学附属中山医院放射科辽宁大连116000

2型糖尿病(T2DM)认知功能损伤与神经血管耦联(NVC)改变存在密切关系,但目前对于具体机制尚不完全清楚。利用功能MRI(fMRI)技术可联合解析T2DM患者NVC改变,为揭示T2DM所致认知功能障碍的机制提供了新思路。本文就fMRI探索T2DM所致NVC改... 详细信息

2型糖尿病(T2DM)认知功能损伤与神经血管耦联(NVC)改变存在密切关系,但目前对于具体机制尚不完全清楚。利用功能MRI(fMRI)技术可联合解析T2DM患者NVC改变,为揭示T2DM所致认知功能障碍的机制提供了新思路。本文就fMRI探索T2DM所致NVC改变进展进行综述。

关键词：糖尿病,2型神经血管耦联脑血管循环磁共振成像

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