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考虑风险容忍度的双渠道绿色供应链运营决策及协调研究

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控制与决策 2024年第6期39卷 2106-2112页

作者：张涑贤王梓豪王文隆西安建筑科技大学管理学院西安710055 西北农林科技大学经济管理学院陕西杨凌712100

针对双渠道绿色供应链,在考虑各方不同风险容忍度的基础上,构建以制造商为主导的供应链博弈模型,利用均值方差法分析集中式决策和批发价格契约下参与方的运营决策和期望利润,并设计协调契约.研究发现:在批发价格契约下,产品绿色度与制... 详细信息

针对双渠道绿色供应链,在考虑各方不同风险容忍度的基础上,构建以制造商为主导的供应链博弈模型,利用均值方差法分析集中式决策和批发价格契约下参与方的运营决策和期望利润,并设计协调契约.研究发现:在批发价格契约下,产品绿色度与制造商风险容忍度正相关,与零售商风险容忍度无关;最优零售价格均与双方风险容忍度正相关,且线上价格基准系数与直销价格负相关,与零售价格正相关;当绿色产品对消费者需求影响较大时,零售商的期望利润与制造商风险容忍度正相关.带有转移支付的反向收益共享与成本分担组合契约可实现双渠道绿色供应链的协调.

关键词：双渠道绿色供应链风险容忍度定价产品绿色度协调契约运营决策

优化公共空间:提升铸牢中华民族共同体意识的社会凝聚力

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民族教育研究 2024年第3期35卷 28-35页

作者：王延隆浙江中医药大学马克思主义学院浙江杭州311402 南京大学雨花台红色文化研究院博士后工作站江苏南京210012

公共空间是社会凝聚力维系和强化的标志性场域,不仅是物理空间、社会空间、情感空间叠加交汇的基本单元,亦是强化个体及群体空间邻近度、消弭区隔鸿沟的重要纽带。铸牢中华民族共同体意识是各族群众在特定的公共空间中、共同的交往实践... 详细信息

公共空间是社会凝聚力维系和强化的标志性场域,不仅是物理空间、社会空间、情感空间叠加交汇的基本单元,亦是强化个体及群体空间邻近度、消弭区隔鸿沟的重要纽带。铸牢中华民族共同体意识是各族群众在特定的公共空间中、共同的交往实践中逐步形成和强化的。公共空间以共同的公共场所、互嵌的社会关系、特有的场所精神为铸牢中华民族共同体意识提供了强有力的空间支撑。以公共空间为视角,基于物理、社会、情感三重维度构建表征中华民族凝聚力的空间符码和分析框架,以高校大学生公共空间为个案,廓清邻里空间区隔、社会资本培育、集体记忆强化的空间运作机制,提出优化生活实践的物理空间,营造平等发展的社会空间,拓宽“五个认同”的情感空间的实践路向,构建集地缘、利益和价值三位一体的空间共同体,为公共空间提升铸牢中华民族共同体意识的社会凝聚力提供有益参考和借鉴。

关键词：公共空间铸牢中华民族共同体意识社会凝聚力高校大学生

科学社会主义视阈中党的理论创新的原理性成果

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毛泽东邓小平理论研究 2024年第6期 1-8,107页

作者：王公龙中共上海市委党校马克思主义学院上海市马克思主义研究会

党的十八大以来,我们党围绕坚持和发展科学社会主义,在社会主义本质、社会主义的根本目的、社会主义的根本立场、社会主义发展理念、社会主义国家治理、社会主义的生态理念、社会主义执政党建设、社会主义全球愿景、社会主义现代化道路... 详细信息

党的十八大以来,我们党围绕坚持和发展科学社会主义,在社会主义本质、社会主义的根本目的、社会主义的根本立场、社会主义发展理念、社会主义国家治理、社会主义的生态理念、社会主义执政党建设、社会主义全球愿景、社会主义现代化道路等方面,创造性地提出一系列原理性理论成果。这些原理性理论成果的提出不仅极大激活了科学社会主义的时代生命力,为习近平新时代中国特色社会主义思想夯实了理论基础,也有力推动了科学社会主义在当代中国的发展,成功构建起当代中国科学社会主义理论形态。

关键词：理论创新原理性理论成果科学社会主义习近平新时代中国特色社会主义思想

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律师庭外言论的规制逻辑与模式转型

内蒙古社会科学 2024年第5期45卷 133-142页

作者：王迎龙中国政法大学法学院北京100088

律师庭外言论是律师法庭辩护的必要延伸,对于促进司法公正的实现具有重要意义。同时,自媒体时代律师庭外言论的特点也决定了规制律师庭外言论的必要性。问题的关键在于如何有效规范律师庭外言论、确立庭外言论的衡量标准。我国对于律师... 详细信息

律师庭外言论是律师法庭辩护的必要延伸,对于促进司法公正的实现具有重要意义。同时,自媒体时代律师庭外言论的特点也决定了规制律师庭外言论的必要性。问题的关键在于如何有效规范律师庭外言论、确立庭外言论的衡量标准。我国对于律师庭外言论的规制属于司法秩序模式,以司法秩序的维护为价值导向,应当由行政管控转向审理公正的规制逻辑,实现审理公正的模式转型。具体而言,在衡量律师庭外言论正当与否方面,应确立实质危险与道德性相结合,即主客观相统一的评判标准,实质危险是指律师庭外言论可能或已经对司法公正造成实质损害,这是非正当庭外言论的形式特征;道德性与非道德性相对,律师基于法律职业伦理为当事人谋取合法利益,在相对意义上即具有了道德性。此外,法律还应明确规定“禁止区”与“安全区”,为律师庭外言论的发表提供清晰明确的规范指引。

关键词：自媒体律师庭外言论道德性实质危险法律职业伦理

政府主导型与市场主导型发展模式经济绩效比较--基于江浙两省经济发展的长时段考察

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南通大学学报（社会科学版） 2024年第2期40卷 41-54页

作者：王文龙绍兴文理学院商学院

市场主导型发展模式应是中国经济发展的长期战略选择。根据可比性标准分别选择江苏省与浙江省作为政府主导型与市场主导型经济发展模式的样本,通过对江浙两省经济发展效益、经济竞争力和分配公平性三个指标的长时段综合考察,得到浙江省... 详细信息

市场主导型发展模式应是中国经济发展的长期战略选择。根据可比性标准分别选择江苏省与浙江省作为政府主导型与市场主导型经济发展模式的样本,通过对江浙两省经济发展效益、经济竞争力和分配公平性三个指标的长时段综合考察,得到浙江省市场主导型发展模式经济绩效更优的结论。浙江省市场主导型发展模式绩效更优的主要原因在于坚持市场在资源配置中的决定性作用,大力发展民营经济,积极培育产业集群,持续推进省直管县体制改革壮大县域经济,不断提高政府宏观调控能力。各地政府应借鉴浙江经验积极地进行制度创新,改善民营经济发展环境,提高产业竞争力,发展县域经济,转变政府职能。只有继续坚持市场化改革,不断把改革开放推向深入,才能重振中国经济,有效化解社会矛盾,实现可持续发展。

关键词：发展模式政府主导型市场主导型经济绩效

AICAR-based exercise mimetic alleviates aging-induced memory impairment through activating AMPK and improving mitochondrial quality control

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Food Science and Human Wellness 2024年

作者： Bo Liao Yuan-Yuan Qin Shan-Yao Pan Gui-Ping wang Zhi Jiang Bin Li Yao wang Yu-long wang Ming-Chao Zhou Yong Zhang Gang Liu Zheng-Hong Qin Xue-Feng Xi Li Luo Department of Pharmacology and Laboratory of Aging and Nervous Diseases (SZS0703) Jiangsu Key Laboratory of Translational Research and Therapy for NeuroPsycho-Diseases， Soochow University School of Pharmaceutical Science College of Physical Education， Henan University School of Physical Education and Sports Science， Soochow University Department of Pharmacy， Suzhou Hospital of Traditional Chinese Medicine Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine Laboratory Animal Center， Medical College of Soochow University Center Lab of Ninth People's Hospital of Suzhou Department of Rehabilitation Medicine， Nan‘ao People's Hospital of Dapeng New District Rehabilitation Department， The First Affiliated Hospital of Shenzhen University， Shenzhen Second People's Hospital Tianjin Key Lab of Exercise Physiology and Sports Medicine， Tianjin University of Sport Department of Rehabilitation Medicine， Nanfang Hospital， Southern Medical University

Growing evidence suggests that exercise can provide neuroprotection by improving mitochondrial quality control (MQC) on the aged brain. Adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) signaling responsiveness declines with aging. However， whether AMPK plays a role in the exercise-mediated improvement of memory and MQC in the aged hippocampus remains to be established. AICAR (5-Aminoimidazole 4-carboxamide ribonucleoside)， a pharmacological agonist of AMPK， has been proposed to be an exercise mimetic recently. However， it has not been clarified whether AICAR could mimic the effects of exercise on the aged hippocampus through improvement of MQC. In this study， AICAR (AMPK agonist) and Compound C (AMPK inhibitor) were used to investigate if AMPK plays a key role in exercise-induced improvement of MQC and if AICAR could act as an exercise mimetic through improvement of MQC in aged hippocampus. Both exercise and AICAR improved the memory of aged mice and increased AMPK phosphorylation in the aged hippocampus. Exercise， but not AICAR， improved mitochondrial respiratory function in the aged hippocampus and increased the Microtubule associated protein 1 light chain 3 (LC3) II/LC3 I ratio and the protein expression of LC3 II and Autophagy Related Protein 7 (ATG7) in the lysate of whole hippocampal tissue. Both exercise and AICAR increased the ratio of LC3 II/LC3 I and the protein expression of LC3 II in the mitochondrial fractions of the hippocampus. Regarding mitochondrial dynamics， neither exercise training nor AICAR changed the protein level of Mitofusin2 (Mfn2). Exercise， but not AICAR， increased the protein level of Dynamin-related protein 1 (Drp1). Furthermore， both exercise training and AICAR increased the protein level of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α)， a modulator of mitochondrial biogenesis. Compound C abolished the exercise-induced effects on memory in aged mice (Fig. 1)， AMPK phosphorylation， autophagy， mitop

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New application of intestinal obstruction catheter in enterocutaneous fistula:A case report

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World Journal of Clinical Cases 2024年第20期12卷 4384-4390页

作者： Xiao-Tong wang long wang An-Lin Liu Jing-Le Huang Lei Li Zhi-Xing Lu Wei Mai Departments of Gastrointestinal Hernia and Enterofistula SurgeryPeople's Hospital of Guangxi Zhuang Autonomous Region&Institute of Minimally Invasive Technology and ApplicationsNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Enterocutaneous fistula(ECF)is an abnormal connection between the gastrointestinal tract and the *** can lead to massive body fluid loss,hypercatabolism,and ***,nutritional support plays a crucial role in managing ECFs and promoting the healing of *** nutritional support,enteral nutrition(EN)is the preferred method when gastrointestinal function is ***,various EN approaches have been applied for different anatomical positions of the ***,the effectiveness of administering EN support for treating lower ECFs still needs further exploration and *** SUMMARY We present the case of a 46-year-old male who underwent gastrointestinal stromal tumour *** days after the surgery,the patient presented with fever,fatigue,severe upper abdominal pain,and septic ***,lower ECFs were diagnosed through laboratory and imaging *** addition to symptomatic treatment for homeostasis,total parenteral nutrition support was administered in the first 72 h due to dysfunction of the *** that,we gradually provided EN support through the intestinal obstruction catheter in consideration of the specific anatomic position of the fistula instead of using the nasal jejunal ***,the patient could receive optimal EN support via the catheter,and no complications were found during the *** Nutritional support is a crucial element in ECF management,and intestinal obstruction catheters could be used for early EN administration.

关键词： Enterocutaneous fistula Intestinal obstruction catheter Nutritional support Enteral nutrition pathway Case report

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运行7年污水源脱盐中水厂的提量提标改造

中国给水排水 2024年第16期40卷 126-130页

作者：王金龙青岛锦龙弘业环保有限公司山东青岛266555

某脱盐中水厂以双膜工艺为核心,采用短流程布置方式,设计产水规模2×10^(4) m^(3)/d,以污水处理厂一级A达标出水为原水,产水电导率<200μS/cm,已运行近7年,基本满负荷运行。由于园区用户用水量增加,该厂需扩容25%,在提量的同时进行提标... 详细信息

某脱盐中水厂以双膜工艺为核心,采用短流程布置方式,设计产水规模2×10^(4) m^(3)/d,以污水处理厂一级A达标出水为原水,产水电导率<200μS/cm,已运行近7年,基本满负荷运行。由于园区用户用水量增加,该厂需扩容25%,在提量的同时进行提标改造,而改造面临占地受限、脱盐要求和供水保障率要求高、膜老化、原水电导率高等问题。通过将已使用近7年的双膜更换、超滤建设双层增加2组、拆除原3组二级RO增加2组一级RO、引入优质原水水源等综合方式,实现原位提量25%,并实现产水电导率<150μS/cm。其中,反渗透采用国产膜实现了对进口膜的部分替代。建议多组系统生产过程中尝试包括国产膜在内多种新产品,在实践中检验技术经济指标,为后续换膜积累数据,实现用户效益最大化。在设计方面,对于污水源双膜工艺,短流程具备可行性,但应关注设计温度、产率系数、原水水质取值准确性,反渗透设计应有一定余量。

关键词：中水脱盐超滤反渗透扩容膜更换

Proteomic profiling of cerebrospinal fluid in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease

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World Journal of Pediatrics 2024年第3期20卷 259-271页

作者： Yi-long wang Meng-Ying Zhu Zhe-Feng Yuan Xiao-Yan Ren Xiao-Tong Guo Yi Hua Lu Xu Cong-Ying Zhao Li-Hua Jiang Xin Zhang Guo-Xia Sheng Pei-Fang Jiang Zheng-Yan Zhao Feng Gao Department of Neurology Children's HospitalZhejiang University School of MedicineHangzhou 310052China Children's Hospital Zhejiang University School of MedicineHangzhou 310052China Children's Hospital National Clinical Research Center for Child HealthZhejiang University School of MedicineHangzhou 310052China

Background Myelin oligodendrocyte glycoprotein(MOG)antibody-associated disease(MOGAD)is an autoimmune demy-elinating disorder of the central nervous *** Extracted proteins from 34 cerebrospinal fluid(CSF)samples[patients with MOGAD(MOG group,n=12);healthy controls(HC group,n=12);patients with MOG seronegative and metagenomics next-generation sequencing-negative inflammatory neurological diseases(IND group,n=10)]were processed and subjected to label-free quantitative *** partial least squares-discriminant analysis(PLS-DA)and orthogonal PLS-DA(O-PLS-DA)models were also performed based on proteomics *** analysis of differentially expressed proteins(DEPs)was performed using Gene Ontology,InterPro,and Kyoto Encyclopedia Genes and *** enzyme-linked immunosorbent assay was used to determine the complement levels in serum from patients with *** Four hundred and twenty-nine DEPs(149 upregulated and 280 downregulated proteins)were identified in the MOG group compared to the HC group according to the P value and fold change(FC).Using the O-PLS-DA model,872 differentially abundant proteins were identified with variable importance projection(VIP)scores>*** proteins(gamma-glutamyl hydrolase,cathepsin F,interalpha-trypsin inhibitor heavy chain 5,latent transforming growth factor beta-binding protein 4 and leukocyte-associated immunoglobulin-like receptor 1)overlapping between the top 30 DEPs with top-ranked P value and FC and top 30 proteins in PLS-DA VIP lists were *** analysis revealed that the dysregulated proteins in the MOG group were primarily involved in complement and coagulation cascades,cell adhesion,axon guidance,and glycosphingolipid biosynthesis compared to the HC *** The proteomic alterations in CSF samples from children with MOGAD identified in the current study might provide opportunities for developing novel biomarker candidates.

关键词： Acute disseminated encephalomyelitis Cerebrospinal fluid Complement cascades Myelin oligodendrocyte glycoprotein-associated disease Proteomics