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Using Healthcare Big Data Analytics to Improve Women’s Health:Benefits,Challenges,and Perspectives

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China CDC weekly 2024年第10期6卷 173-174页

作者： Heling Bao hui Liu Linhong wang Institute of Medical Information Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina National Center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Women’s Health Care Branch Chinese Preventive Medicine AssociationBeijingCh

Women’s health is of paramount importance for the attainment of the Sustainable Development Goals(SDGs)and Healthy China 2030,encompassing reproductive health and physical and mental *** multifaceted concept of healt... 详细信息

关键词： Sustainable maternal Analytics

Monothetic and conductive network and mechanical stress releasing layer on micron-silicon anode enabling high-energy solid-state battery

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Rare Metals 2024年第3期43卷 1017-1029页

作者： Xiang Han Min Xu Lan-hui Gu Chao-Fei Lan Min-Feng Chen jun-Jie Lu Bi-Fu Sheng Peng wang Song-Yan Chen Ji-Zhang Chen College of Materials Science and Engineering Co-Innovation Center of Efficient Processing and Utilization of Forestry ResourcesNanjing Forestry UniversityNanjing210037China Department of Physics Xiamen UniversityXiamen361005China Western Digital Corporation MilpitasCA95035USA

Silicon has ultrahigh capacity,dendrite-free alloy lithiation mechanism and low cost and has been regarded as a promising anode candidate for solid-state *** to the low infiltration of solid-state electrolyte(SSE),not the unstable solid-electrolyte interphase(SEI),but the huge stress during lithiation-and delithiation-induced particle fracture and conductivity lost tend to be the main *** this study,starting with micron-Si,a novel monothetic carbon conductive framework and a MgO coating layer are designed,which serve as electron pathway across the whole electrode and stress releasing layer,*** addition,the in situ reaction between Si and SSE helps to form a LiF-rich and mechanically stable SEI *** a result,the mechanical stability and charge transfer kinetics of the uniquely designed Si anode are significantly ***,high initial Coulombic efficiency,high capacity and durable cycling stability can be achieved by applying the Si@MgO@C anode in *** example,high specific capacity of 3224.6 mAh·g^(-1)and long cycling durability of 200 cycles are *** work provides a new concept for designing alloy-type anode that combines surface coating on particle and electrode structure design.

关键词： Lithium-ion battery(LIB) Solid-state electrolyte(SSE) Silicon anode Stress relief Coating

Mechanisms and active substances of targeting lipid peroxidation in ferroptosis regulation

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Food Science and Human Wellness 2024年第5期13卷 2502-2518页

作者： hui Chen Lingli Chen Wenjun wang Jiangxi Key Laboratory of Natural Products and Functional Food College of Food Science and EngineeringJiangxi Agricultural UniversityNanchang 330045China

Ferroptosis is a novel form of cell death driven by iron-dependent lipid peroxidation and it is implicated in various diseases,such as liver disease,acute kidney injury,cardiovascular disease,neurodegenerative disease and ***-based reactive oxygen species(ROS),particularly lipid hydroperoxides in the cellular membrane can lead to membrane disruption and cell death mediated by *** are three necessary stages involving in the process of lipid peroxidation regulation in ferroptosis,including the synthesis of membrane phospholipids,initiation of lipid peroxidation and clearance of lipid *** this review,we summarized the molecular modulation mechanisms of lipid peroxidation in ferroptosis from the above three stages,as well as various ferroptosis modulators targeting lipid peroxidation,including commonly used products,natural bioactive compounds and ***,these findings suggest the vital role of lipid peroxidation in ferroptosis,and targeting lipid peroxidation in ferroptosis is potential to treat ferroptosis-associated diseases.

关键词： Ferroptosis Lipid peroxidation Mechanisms Natural bioactive compounds Selenocompounds

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A distinction of gliomas at cellular and tissue level by surface-enhanced Raman scattering spectroscopy

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Chinese Chemical Letters 2024年第5期35卷 423-427页

作者： Chengde wang Liping Huang Shanshan wang Lihao Wu Yi wang jun Dong Department of Neurosurgery The Second Affiliated Hospital of Soochow UniversitySuzhou 215004China Department of Neurosurgery The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000China School of Ophthalmology and Optometry Eye HospitalSchool of Biomedical EngineeringWenzhou Medical UniversityWenzhou 325001China Department of Chemistry School of Science and Research Center for Industries of the FutureWestlake UniversityHangzhou 310030China

Glioblastoma multiforme(GBM)is the most common malignant primary brain tumor in *** precise identification and distinction of GBM heterogeneity from surrounding brain parenchyma at the cellular level and even at the tissue level are important for GBM *** this study,GBM cells are distinguished from normal astrocytes and non-central nervous system(CNS)tumor cells by surface-enhanced Raman scattering(SERS)based on gold nanoshell(SiO_(2)@Au)particles and support vector machine(SVM)*** addition,the gold nanoisland(AuNI)SERS substrates are further developed and explored for accurate detection of GBM at the tissue *** distinction between glioma and trauma tissues,identification of different tumor grades,and IDH mutation are realized with the assistance of orthogonal partial least squares discriminant analysis(OPLS-DA)in a rapid,non-invasive,and convenient *** results show that the developed SERS-based analytical method has the potential for practical application for the detection of GBM at the single-cell and tissue levels and even for real-time intraoperative diagnosis.

关键词： Glioblastoma multiforme(GBM) Surface-enhanced Raman scattering(SERS) Nanoparticle Nanoisland Machine learning

Corrosion behavior and protection mechanism of carbon steel coated with ethylene chlorotrifluoroethylene(ECTFE)

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第6期25卷 502-515页

作者： Peihu SHEN jun WEN Biqin DONG Hedong LI Minjia wang School of Civil Engineering and Architecture Zhejiang Sci-Tech UniversityHangzhou310018China College of Civil and Transportation Engineering Shenzhen UniversityShenzhen518061China Zhejiang Research Institute of Chemical Industry Co. Ltd.Hangzhou310023China

Ethylene chlorotrifluoroethylene(ECTFE)coating was applied to the surface of carbon steel through electrostatic spraying and low-temperature heat *** morphology and structure of the coating were analyzed using various characterization *** electrochemical data of the coated steel soaked in 3.5%(mass fraction)NaCl solution for 90 d at different periods were also *** findings indicate that the outer surface of the coating remains structurally stable before and after soaking.F can diffuse into the steel substrate,facilitating the bonding between the coating and the steel substrate,but the free F also induces a weakening effect on the crystalline *** to the thickness of the coating edge and the susceptibility to infiltration of the corrosive medium,under-film micro-zone corrosion occurs at a slow *** soaking for 90 d,the impedance modulus measures approximately 10^(4)Ω·cm^(2),and the open circuit potential(OCP)is−0.61 *** self-corrosion current density is 1.13×10^(−6)A/cm^(2),resulting in a calculated coating protection rate of 99.29%.In summary,despite edge corrosion occurring,the ECTFE coating provides excellent corrosion protection.

关键词： Coating Fluorine resin Edge corrosion Corrosive behavior Electrochemical performance

东北夏季气温变异的区域差异及其与大气环流和海表温度的关系

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地球物理学报 2006年第3期49卷 662-671页

作者：孙建奇王会军中国科学院大气物理研究所大气科学和地球流体力学数值模拟国家重点实验室(LASG)

利用1951～2000年中国东北地区23个台站资料,对东北夏季气温的时空分布进行了研究,发现其变化除具有整体的一致性外,东北南部和北部的夏季气温在年际和年代际时间尺度都表现出很大不同,其中北部区域的夏季气温在1987～1988年间发生了一... 详细信息

利用1951～2000年中国东北地区23个台站资料,对东北夏季气温的时空分布进行了研究,发现其变化除具有整体的一致性外,东北南部和北部的夏季气温在年际和年代际时间尺度都表现出很大不同,其中北部区域的夏季气温在1987～1988年间发生了一次显著的气候突变.另外,剔除夏季气温全区一致变化的年份后,南北两区夏季气温与大气环流和海表温度的关系表明：突变前,影响北部和南部冷/热夏季的大气环流形势存在显著的不同,关键海域亦有很大差异：影响南部的为中纬度西太平洋和印度洋部分海域,影响北部的主要为ENSO事件;突变后,两区的夏季气温及相应大气环流和关键海区都趋于一致.在整个分析时段内,北部夏季气温与东亚夏季风存在显著负相关,而南部的关系则不明显.

关键词：东北夏季气温大气环流 ENSO 东亚夏季风

Hadley环流的年际和年代际变化特征及其与热带海温的关系

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地球物理学报 2006年第5期49卷 1271-1278页

作者：周波涛王会军中国科学院大气物理研究所竺可桢-南森国际研究中心

利用NCEP/NCAR再分析风场资料和NOAA海表温度(SST)资料,分析了冬、夏季Hadley环流的变化特征及其与热带海温在年际、年代际尺度上的关系.结果表明,冬季北半球Hadley环流强度具有明显的年际和年代际变化,同时还呈现出明显的增强趋势.伴随... 详细信息

利用NCEP/NCAR再分析风场资料和NOAA海表温度(SST)资料,分析了冬、夏季Hadley环流的变化特征及其与热带海温在年际、年代际尺度上的关系.结果表明,冬季北半球Hadley环流强度具有明显的年际和年代际变化,同时还呈现出明显的增强趋势.伴随着Hadley环流的加强,环流中心位置南移,高度上升;夏季南半球Hadley环流变化主要表现为强、弱、强的年代际振动,没有明显的线性趋势.研究还显示冬季Hadley环流与Nino3区SST正相关,这种相关性具有年代际变化特征.年际尺度上,冬季北半球Hadley环流与Nino3区SST正相关;夏季南半球Hadley环流与Nino3区SST负相关,即当赤道中东太平洋SST异常偏暖(冷)时,冬、夏季Hadley环流变强(弱).

关键词： Hadley环流年际变化年代际变化热带海温

Transient state analysis of a rub-impact rotor system during maneuvering flight

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Chinese Journal of Aeronautics 2024年第7期37卷 236-251页

作者： jun wang Yunfei LIU Zhaoye QIN Liang MA Fulei CHU Beijing Key Laboratory of Health Monitoring and Self-Recovery for High-End Machinery Equipment Beijing University of Chemical TechnologyBeijing 100029China State Key Laboratory of Tribology Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China College of Aeronautical Engineering Civil Aviation University of ChinaTianjin 300300China

Maneuvering flight substantially affects the dynamic behavior of rotors;particularly,such flight may cause rubbing between a rotor and stator,which is one of the most serious damages in aircraft *** this paper,a nonlinear dynamic model for describing the dynamic characteristics of a rub-impact rotor system during maneuvering flight is established based on the Lagrange ***,numerical simulations employing the Newmark method are performed,delving into the detailed discussion of the influence of parameters such as rotational speed and maneuvering flight on the transient and steady-state responses of the rotor *** effect mechanism of maneuver load and its coupling with rub impact is *** results show that the impact response induced by maneuvering flight is more obvious in the subcritical state than in the supercritical *** additional stiffness and damping are also induced;in particular,the additional damping has a coupling ***,the rub impact imposes an additional constraint on the rotor system,thereby weakening the influence of the maneuver load and becoming the major factor that determines the dynamic behavior of the rotor system at high speeds.

关键词： Maneuvering flight Rub impact Rotor system Dynamic response Impact response

A robust viscoelastic surfactant tolerating 20% HCl up to 150℃ for oil well stimulation

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Petroleum Science 2024年第3期21卷 1865-1874页

作者： Ji wang Ning Qi Hong-Yao Yin Yu-jun Feng Polymer Research Institute State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065SichuanPR.China Tianfu Yongxing Laboratory New Theory and Technology of CO_(2) Capture Research CenterChengdu610065SichuanPR China School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongPR China

Viscoelastic surfactants(VES)are often used as viscous diverters in acidizing stimulation to prolong the acid consumption time and maximize zonal coverage of the acid for improving well ***,the ceiling temperature of commercial VES cannot exceed 120℃in practical use because of the poor thermal stability and fragile molecular structure,hindering their implementation in hightemperature oil reservoirs,i.e.,≥150℃.Here we synthesized a novel C22-tailed diamine,N-erucaminopropyl-N,N-dimethylamine(EDPA),and examined comparatively its rheological behavior,assemblies morphology and molecular stability in 20 wt%HCl with a commercial VES,erucyl dimethyl amidopropyl betaine(EDAB).The feasibility of EDPA for acidizing stimulation was assessed by acid etching of carbonate rock with its HCl solution at 150℃.Rheological results showed that the 2.5 wt%EDPA—20 wt%HCl solution maintains stable viscosity of 90 m Pa s at 150℃for 60 min,while that of 2.0 wt%EDAB HCl solution is just 1 m Pa s under identical conditions.1H NMR spectra and cryo-TEM observations revealed that the chemical structure and self-assembled architectures of EDPA remained intact in such context,but the EDAB suffered from degradation due to the hydrolysis of the amide group,accounting for the poor heat-resistance and *** reaction rate of 2.5 wt%EDPA HCl solution with carbonate rock was one order of magnitude lower than that of 20 wt%HCl solution at 150℃,underpinning the potential of EDPA to be used in the high-temperature reservoirs *** work improved the thermal tolerance of VES in highly concentrated HCl solution,paving a feasible way for the acidization of high-temperature reservoir environments(~150℃).

关键词： Viscoelastic surfactants Thermal stability Self-diverting acid Wormlike micelles Acidizing stimulation