检索结果-南通市图书馆

A highly linear stretchable MXene-based biocompatible hydrogel-elastomer hybrid with tissue-level softness

Science china Materials 2024年第10期67卷 3368-3378页

作者： Shu wan Haizhou Huang Zisheng he Yizhou Ye Shen Li Shi Su Jiaxin Shen Longxiang Han Peng wan Xu Ran Li Chen Xuefeng he Litao Sun hengchang Bi Key Laboratory of Optoelectronic Technology and Systems Ministry of EducationKey Disciplines Laboratory of Novel Micro-Nano Devices and System TechnologySchool of Optoelectronics EngineeringChongqing UniversityChongqing 400044China College of Photonic and Electronic Engineering Fujian Normal UniversityFuzhou 350117China School of Aeronautical Engineering Nanjing Vocational University of Industry TechnologyNanjing 210023China SEU-FEI Nano-Pico Center Key Laboratory of MEMS of Ministry of EducationCollaborative Innovation Center for Micro/Nano FabricationDevice and SystemSoutheast UniversityNanjing 210096China The Shanghai Key Laboratory of Multidimensional Information Processing School of Communication and Electronic EngineeringEast China Normal UniversityShanghai 200241China

Maintaining low modulus while endowing the wide-range linear stretchability to wearable or implantable devices is crucial for these devices to reduce the mechanical mismatch between the devices and human skin/tissue ***,improving linear stretchability often results in an increased modulus of stretchable electronic materials,which hinders their conformability in long-term quantifiable monitoring of ***,we develop a hybrid structure involving interlocking low-modulus porous elastomers(Ecoflex-0030)and MXene-based hydrogels with crosslinking networks of polyvinyl alcohol,sodium alginate,and *** hydrogel–elastomer structure exhibits superior performance compared with previous reports,with a wide linear stretchability strain range from 0 to 1000%and maintaining a low modulus of 6.4 ***,the hydrogel–elastomer hybrids can be utilized as highly sensitive strain sensors with remarkable characteristics,including high sensitivity(gauge factor~3.52),a linear correlation between the resistance and strain(0–200%),rapid response(0.18 s)and recovery times(0.21 s),and excellent electrical reproducibility(1000 loading–unloading cycles).Those electrical and mechanical properties allow the sensor to act as a suitable quantifiable equipment in organ monitoring,human activities detecting,and human–machine interactions.

关键词： linear stretchability low modulus MXene hydrogel-elastomer hybrid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Five-blade scratcher for treating severe rhinophyma:A retrospective study

引用

World Journal of Clinical Cases 2024年第20期12卷 4180-4190页

作者： Yu-Ping Zheng Xu-Feng he Yan-Feng Zhang Lan-Xin Geng Hui-Min Zhang Hua wan Xiang he Department of Dermatology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Galactophore Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China

BACKGROUND Rhinophyma,a late-stage subtype of rosacea,is characterized by excessive sebaceous glands and connective tissue *** may experience respiratory disturbances and psychological distress that significantly affect their quality of life when excessive nasal hyperplasia obstructs the external nasal *** is the treatment of choice for ***,excessive bleeding,scarring,pigmentation,and high recurrence rates frequently characterize current surgical *** To evaluate the clinical effectiveness and recurrence rates after treating severe rhinophyma with the five-blade *** This study retrospectively analyzed the clinical records of 28 patients with severe rhinophyma *** Global Flushing Severity Score(GFSS),Clinician Erythema Assessment(CEA),Rhinophyma Severity Index(RHISI),Glasgow Benefit Inventory(GBI),and satisfaction scores were used to assess the recovery of patients at 6 months and 5 years,with the recurrence rate calculated at 5 years *** addition,the levels of pro-inflammatory factors(TNF-α,IL-1β,and IL-6)in the serum of patients before and after surgery were detected by *** The GFSS,CEA,and RHISI scores at 6 months and 5 years postoperatively were significantly lower than those preoperatively(P1 for both periods).Five-blade scratcher treatment greatly benefits patients as demonstrated by the GBI and patient satisfaction.A small number of patients(7/28,25%)reported recurrence after surgical treatment for rhinophyma in our department that was not more serious than before *** expression of pro-inflammatory factors(TNF-α,IL-1β,and IL-6)in the patient's serum was significantly reduced after surgery of five-blade *** The five-blade scratcher treatment demonstrates notable advantages,including simplicity,safety,efficacy,and cost-effectiveness,coupled with reduced bleeding,minimized scarring,lower recurrence rates,reduced the level of pro-infla

关键词： Rhinophyma Five-blade scratcher Retrospective study Efficacy Recurrence rate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of CpG-ODN on gene expression in formation of foam cells

引用

Acta Pharmacologica Sinica 2005年第11期26卷 1359-1364页

作者： Kai LI, Bin wan, Zhen-lin HU, Ying he, Xiao-wen he, Lei JIANG, Shu-han SUN~2 Department of medical Genetics, College of Basic medical Sciences, the Second Military medical university, Shanghai 200433, china Department of medical Genetics College of Basic Medical Sciences the Second Military Medical University Shanghai China

Aim: To investigate the effects of CpG-oligodeoxynucleotide (CpG-ODN) on the formation of macrophage foam cells and related gene expression. Methods: A gene expression profile was examined by microarray techniques, and mRNA expression was detected by reverse transcriptase polymerase chain reaction (RT-PCR). The cholesterol and cholesteryl ester contents of cells were determined by high performance liquid chromatography. Results: CD36, LPL, and Fcγ2b, which were related to lipid metabolism and the formation of macrophage foam cells, were upregulated after CpG-ODN stimulation. The mRNA expression related to the formation of foam cells was confirmed by semiquantitative RT-PCR. Moreover, histochemical analysis confirmed that lipid deposits inside cells increased after CpG-ODN treatment. However, using flow cytometry, we found that CpG-ODN had no effect on the expression of membrane receptors. Conclusion: CpG-ODN up-regulated the expression of genes in macrophage foam cell formation.

关键词： CpG islands oligodeoxyribonucleotides foam cells macrophages LDL lipoprotein gene expression cholesterol CD 36 antigens lipoprotein lipase Fc gamma receptor Ⅱb

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

地区经济复杂度对对称关联性产业分化的影响

引用

地理学报 2024年第8期79卷 1994-2019页

作者：李伟伏怡铭王宛贺灿飞南京师范大学地理科学学院南京210023 江苏省地理信息资源开发与利用协同创新中心南京210023 可持续发展大数据国际研究中心北京100094 中国宏观经济研究院北京100038 北京大学城市与环境学院北京100871 北京大学-林肯研究院城市发展与土地政策研究中心北京100871

演化经济地理学提出了区域产业演化的关联法则,基于关联性的强弱将区域产业演化划分为关联性产业分化与非关联性产业创生,但当前研究忽视了关联性产业分化中的对称性与非对称性问题。在现有理论基础上,本文将关联性产业分化划分为对称... 详细信息

演化经济地理学提出了区域产业演化的关联法则,基于关联性的强弱将区域产业演化划分为关联性产业分化与非关联性产业创生,但当前研究忽视了关联性产业分化中的对称性与非对称性问题。在现有理论基础上,本文将关联性产业分化划分为对称关联性产业分化和非对称关联性产业分化(又分为正向非对称关联性产业分化和负向非对称关联性产业分化),基于1998—2012年中国工业企业数据库实证研究对称关联性产业分化与非对称关联性产业分化的数量特征、产业特征及其与地区经济复杂度的关系。结果表明:①中国区域产业演化以关联性产业分化为主,在关联性产业分化中又以正向非对称关联性产业分化为主、对称关联性产业分化次之。1998—2012年中国关联性新产业占新产业总数的60%~70%左右。正向非对称关联性新产业数量占关联性新产业总数的60%左右,对称关联性新产业占关联性新产业总数的35%左右。②高技术产业的关联性分化表现出更强的对称性,而低技术产业的关联性分化表现出更强的正向非对称性。③经济复杂度越高的地区往往具有更多的非关联性产业创生,其关联性产业分化表现出更强的对称性。经济复杂度较低的地区拥有更多的关联性产业分化,并且该关联性产业分化表现出更强的正向非对称性。本文进一步拓展了区域产业演化的关联法则,并可对区域产业新旧动能转换提供政策建议。

关键词：关联性对称关联性与非对称关联性经济复杂度区域产业演化演化经济地理学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Low Gilbert damping in Bi/In-doped YIG thin films with giant Faraday effect

引用

Chinese Physics B 2024年第10期33卷 419-426页

作者： Jin Zhan Yi wang Xianjie wang Hanxu Zhang Senyin Zhu Lingli Zhang Lingling Tao Yu Sui Wenqing he Caihua wan Xiufeng Han V.I.Belotelov Bo Song School of Physics Harbin Institute of TechnologyHarbin 150001China Beijing National Laboratory for Condensed Matter Physics and Institute of PhysicsChinese Academy of SciencesBeijing 100190China Russian Quantum Center Moscow 119991Russia National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Harbin Institute of TechnologyHarbin 150001China Zhengzhou Research Institute Harbin Institute of TechnologyZhengzhou 450046China Frontiers Science Center for Matter Behave in Space Environment Harbin Institute of TechnologyHarbin 150001China

Magnetic films with low Gilbert damping are crucial for magnonic devices,which provide a promising platform forrealizing ultralow-energy *** this study,low Gilbert damping and coercive field were observed in Bi/In-dopedyttrium iron garnet(BiIn:YIG)thin *** BiIn:YIG(444)films were deposited onto different substrates using pulsedlaser *** coercivity(1 Oe)with saturation magnetization of 125.09 emu/cc was achieved along the in-planedirection of BiIn:YIG *** values of Gilbert damping and inhomogeneous broadening of ferromagnetic resonance inBiIn:YIG films were obtained to be as low as 4.05×10^(-4)and 5.62 Oe,*** addition to low damping,the giantFaraday rotation angles(up to 2.9×10^(4)deg/cm)were also observed in the BiIn:YIG *** modifying the magneticstructure and coupling effect between Bi^(3+)and Fe^(3+)of Bi:YIG,doped In^(3+)plays a key role on variation of the *** low damping and giant Faraday effect made the BiIn:YIG film an appealing candidate for magnonic andmagneto-optical devices.

关键词： magnonic device Gilbert damping Faraday effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

GH4169合金超薄带材U形弯曲回弹行为研究

引用

机械工程学报 2024年第14期60卷 174-184页

作者：贺炜林孟宝万敏北京航空航天大学机械工程及自动化学院北京100191

以镍基高温合金GH4169超薄带材为研究对象,构建了考虑晶粒尺寸和晶界的本构关系,与通过单拉试验获得的应力应变曲线对比发现,该模型可以较好地预测不同厚度和晶粒尺寸的GH4169超薄带材的流动行为。为分析材料参数和工艺参数对带材U形弯... 详细信息

以镍基高温合金GH4169超薄带材为研究对象,构建了考虑晶粒尺寸和晶界的本构关系,与通过单拉试验获得的应力应变曲线对比发现,该模型可以较好地预测不同厚度和晶粒尺寸的GH4169超薄带材的流动行为。为分析材料参数和工艺参数对带材U形弯曲回弹的影响,开展了U形弯曲试验。结果表明,回弹角随晶粒尺寸、材料厚度和压边力的增大而减小,而冲压速度对回弹无显著影响。为对比晶粒尺寸、带材厚度、压边力和冲压速度对U形弯曲回弹影响程度的关系,设计了4因素3水平的正交试验,使用所建立的本构模型进行了U形弯曲回弹数值仿真。结果表明,带材厚度对回弹的影响程度最大,其次是压边力和晶粒尺寸,而冲压速度对回弹的影响最小。晶粒尺寸对三个回弹参数的影响均显著,而带材厚度对于回弹角θ2和回弹半径的影响较显著,但对回弹角θ_(1)无明显影响,压边力对于回弹角θ_(1)的影响最为明显,回弹半径ρ次之,对于回弹角θ2的影响最不明显。

关键词： GH4169超薄带材 U形弯曲回弹本构模型尺寸效应

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Andrographolide Attenuates Noise-Induced hearing Loss by Ameliorating Cochlear Inflammation

引用

World Journal of Traditional Chinese Medicine 2024年第2期10卷 204-212页

作者： Meng-Hua Li wan-Qi wang Li-Ting Zheng Meng Bing Chen Yang Chu Miao Qiao Zuo-Li Zhang Konduru Naveena Yong Pan Yun-Shi Zhang he Sun Xiao-Hui Ma Xi Shi Artificial Auditory Laboratory of Jiangsu Province Xuzhou Medical UniversityXuzhouChina Key Laboratory of Tropical Biological Resources of Ministry of Education School of Pharmaceutical SciencesHainan UniversityHaikouChina Department of ENT Beijing Friendship HospitalCapital Medical UniversityBeijingChina National Key Laboratory of Chinese Medicine Modernization Tasly AcademyTasly Pharmaceutical Group Co.Ltd.TianjinChina Endoscopy Center Ankang People's HospitalAnkangChina Department of Respiratory Medicine Xuzhou Infectious Diseases HospitalAffiliated Hospital of Xuzhou Medical UniversityXuzhouChina Department of ENT The People's Hospital of Rongchang DistrictChongqingChina

Objective:This study aimed to explore andrographolide's mechanism of action and its protective effect on noise-induced hearing loss(NIHL).Materials and Methods:A mice animal model for NIHL was established through exposure to broadband noise at 120 d B sound pressure level for 4 *** analysis and pharmacodynamic experiments were carried ***:Andrographolide enters the inner ear and effectively prevents hearing damage following noise exposure in the mice model for permanent hearing ***,treatment with andrographolide inhibited the excessive activation of inflammatory factors in the cochleae of noise-exposed ***:Andrographolide might be a promising candidate for auditory protective drug investigation.

关键词： Andrographolide anti-inflammatory auditory protection noise-induced hearing loss traditional Chinese medicine compound

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Extracellular vesicles from human urine-derived stem cells delay aging through the transfer of PLAU and TIMP1

引用

Acta Pharmaceutica Sinica B 2024年第3期14卷 1166-1186页

作者： Shanshan Rao Zehui he Zun wang Hao Yin Xiongke Hu Yijuan Tan Tengfei wan Hao Zhu Yi Luo Xin wang Hongming Li Zhenxing wang Xinyue Hu Chungu Hong Yiyi wang Mingjie Luo Wei Du Yuxuan Qian Siyuan Tang Hui Xie Chunyuan Chen Department of Orthopedics Movement System Injury and Repair Research CenterXiangya HospitalCentral South UniversityChangsha 410008China Hunan Key Laboratory of Angmedicine Changsha 410008China Xiangya School of Nursing Central South UniversityChangsha 410013China Department of Pediatric Orthopedics Hunan Children’s HospitalUniversity of South ChinaChangsha 410007China Department of Respiratory Medicine Xiangya HospitalCentral South UniversityChangsha 410008China School of Nursing Xinjiang Medical UniversityUrumqiXinjiang 830000China Department of Rehabilitation Xiangya HospitalCentral South UniversityChangsha 410008China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008China

Aging increases the risks of various diseases and the vulnerability to *** senescence is a hallmark of aging that contributes greatly to aging and aging-related *** study demonstrates that extracellular vesicles from human urine-derived stem cells(USC-EVs)efficiently inhibit cellular senescence in vitro and in *** intravenous injection of USC-EVs improves cognitive function,increases physical fitness and bone quality,and alleviates aging-related structural changes in different organs of senescence-accelerated mice and natural aging *** anti-aging effects of USC-EVs are not obviously affected by the USC donors’ages,genders,or health *** analysis reveals that USC-EVs are enriched with plasminogen activator urokinase(PLAU)and tissue inhibitor of metalloproteinases 1(TIMP1).These two proteins contribute importantly to the anti-senescent effects of USC-EVs associated with the inhibition of matrix metalloproteinases,cyclin-dependent kinase inhibitor 2A(P16INK4a),and cyclin-dependent kinase inhibitor 1A(P21cip1).These findings suggest a great potential of autologous USC-EVs as a promising anti-aging agent by transferring PLAU and TIMP1 proteins.

关键词： Extracellular vesicles Urine-derived stem cells Cellular senescence Anti-aging PLAU TIMP1 Senescence-accelerated mice Natural aging mice

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Metal-Organic Framework-Derived Metallic Carbon with Record High Radon Gas Capture Performance

引用

CCS Chemistry 2024年第7期6卷 1789-1797页

作者： Shicheng Gong Yi Tao Lixi Chen Qiuting Xu Junhao Lu Fuyin Ma Xia wang Guodong Li Jun wan Guoxun Ji Linfeng he Xiaohui Yu Duo Zhang Xuhui Sun Zhifang Chai Shuao wang State Key Laboratory of Radiation Medicine and Protection School for Radiological and Interdisciplinary Sciences(RAD-X)and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou 215123 Institute of Functional Nano&Soft Materials Laboratory(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials and DevicesJiangsu Key Laboratory of Advanced Negative Carbon TechnologiesSoochow UniversitySuzhou 215123 School of Environment and Material Engineering Yantai UniversityYantai 264005 Xi’an Research Institute of Hi-Technology Hong Qing TownXi’an 710025 Shanghai Institute of Measurement and Testing Technology Shanghai 201203 Engineering Institute of Advanced Manufacturing and Modern Equipment Technology Jiangsu UniversityZhenjiang 212013

Developing efficient adsorbents for radon(Rn)capture from the ambient environment is of paramount importance for public ***,it poses a great challenge due to the chemical inertness and extremely low molar concentration of Rn in ***,we report a zeolite imidazolate frameworkderived metallic carbon adsorbent(Zn@NPC)with record high Rn removal performance under ambient *** one-step pyrolysis,the prepared Zn@NPC possesses pores with a preference for Rn and atomically dispersed Zn sites,achieving a high Rn removal efficiency that doubles in adsorption coefficient(9.47 L·g^(−1))and triples in adsorption kinetic coefficient(20.25 mL·g^(−1)·min^(−1))over the benchmark Rn adsorbent coconut activated *** functional theory calculations elucidate the important role of the metal polarization effect,which cooperates with the pore size confinement effect to boost the overall Rn adsorption *** work launches a promising alternative for practical Rn capture.

关键词： radon removal metal-organic frameworks microporous carbon synergistic effect dynamic adsorption

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Single-center retrospective study of the diagnostic value of doubleballoon enteroscopy in Meckel’s diverticulum with bleeding

引用

World Journal of Gastrointestinal Surgery 2024年第4期16卷 1043-1054页

作者： Tian he Chao Yang Jing wang Ji-Sheng Zhong Ai-Hua Li Ya-Jing Yin Li-Ling Luo Chun-Mei Rao Nian-Fen Mao Qiang Guo Zan Zuo Wen Zhang Ping wan Yunnan Digestive Endoscopy Clinical medical Center Department of GastroenterologyThe First People’s Hospital of Yunnan ProvinceThe Affiliated Hospital of Kunming University of Science and TechnologyKunming 650032Yunnan ProvinceChina Department of Medicine Kunming University of Science and TechnologyKunming 650093Yunnan ProvinceChina School of Medicine Yunnan University of Traditional Chinese MedicineKunming 650011Yunnan ProvinceChina Department of Gastroenterology Qujing Hospital of Traditional Chinese MedicineQujing 655000Yunnan ProvinceChina Department of Gastroenterology Yunnan University of Traditional Chinese MedicineKunming 650011Yunnan ProvinceChina

BACKGROUND The study aimed to analyze the characteristic clinical manifestations of patients with intestinal disease Meckel’s diverticulum(MD)complicated by digestive tract ***,we aimed to evaluate the value of double-balloon enteroscopy(DBE)in MD diagnosis and the prognosis after laparoscopic diverticula *** To evaluate the value of DBE in the diagnosis and the prognosis after laparoscopic diverticula resection for MD with *** The study retrospectively analyzed relevant data from 84 MD patients treated between January 2015 and March 2022 and recorded their clinical manifestations,auxiliary examination,and follow-up after laparoscopic resection of ***(1)Among 84 MD patients complicated with hemorrhage,77 were male,and 7 were female with an average age of 31.31±10.75 *** incidence was higher in men than in women of different ages;(2)Among the 84 MD patients,65(78.40%)had defecated dark red stools,and 50(58.80%)had no accompanying symptoms during bleeding,indicating that most MD bleeding appeared a dark red stool without accompanying symptoms;(3)The shock index of 71 patients(85.20%)was1,suggesting that the blood loss of most MD patients was less than 20%–30%,and only a few patients had a blood loss of>30%;(4)The DBE-positive rate was 100%(54/54),99mTcpertechnetate-positive scanning rate was 78%(35/45)compared with capsule endoscopy(36%)and small intestine computed tomography(19%).These results suggest that DBE and 99mTc-pertechnetate scans had significant advantages in diagnosing MD and bleeding,especially DBE was a highly precise examination method in MD diagnosis;(5)A total of 54 MD patients with hemorrhage underwent DBE examination before *** endoscopy revealed many mucosal manifestations including normal appearance,inflammatory changes,ulcerative changes,diverticulum inversion,and nodular hyperplasia,with ulcerative changes being the most common(53.70%).This suggests that diverticular mucosal u

关键词： Meckel’s diverticulum with bleeding Double-balloon colonoscopy 99mTc-pertechnetate scanning Capsule endoscopy Ectopic gastric mucosa

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：