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Nano-Micro Letters 2025年第2期17卷 169-186页

作者： Bitgaram Kim Myeong‑Chang Sung Gwang‑Hee Lee Byoungjoon Hwang Sojung Seo Ji‑Hun Seo Dong‑wan Kim Department of Materials Science and Engineering Korea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea School of Civil Environmental and Architectural EngineeringKorea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea Materials Science and Chemical Engineering Center Institute for Advanced Engineering(IAE)Yongin 17180Republic of Korea

A critical challenge hindering the practical application of lithium–oxygen batteries(LOBs)is the inevitable problems associated with liquid electrolytes,such as evaporation and safety *** study addresses these problems by proposing a modified polyrotaxane(mPR)-based solid polymer electrolyte(SPE)design that simultaneously mitigates solvent-related problems and improves ***-SPE exhibits high ion conductivity(2.8×10^(−3)S cm^(−1)at 25℃)through aligned ion conduction pathways and provides electrode protection ability through hydrophobic chain *** this mPR-SPE into solid-state LOBs resulted in stable potentials over 300 *** situ Raman spectroscopy reveals the presence of an LiO_(2)intermediate alongside Li_(2)O_(2)during oxygen *** situ X-ray diffraction confirm the ability of the SPE to hinder the permeation of oxygen and moisture,as demonstrated by the air permeability *** present study suggests that maintaining a low residual solvent while achieving high ionic conductivity is crucial for restricting the sub-reactions of solid-state LOBs.

关键词： Solid polymer electrolyte Lithium-oxygen batteries Polyrotaxane ion conductivity Hydrophobic chain

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《针灸甲乙经》妇人杂病辨证论治规律的探析

中国当代医药 2023年第34期30卷 92-96页

作者：苗冲万健民赵中玮甘肃医学院中医药系甘肃平凉744000

《妇人杂病篇》作为《针灸甲乙经》中妇科病的一篇专论,含有丰富的妇科针灸临床理论。研究表明,该篇通过独特的内容安排,确立了以“无损不足,益有余”为核心的妇科病针灸治疗总则,通过以部列穴的方式,凸显了妇科病症的辨证论治规律。通... 详细信息

《妇人杂病篇》作为《针灸甲乙经》中妇科病的一篇专论,含有丰富的妇科针灸临床理论。研究表明,该篇通过独特的内容安排,确立了以“无损不足,益有余”为核心的妇科病针灸治疗总则,通过以部列穴的方式,凸显了妇科病症的辨证论治规律。通过梳理《针灸甲乙经·妇人杂病第十》的内容安排、选穴规律,发现皇甫谧对妇人杂病的治疗具有独特的辨证论治规律。辨病位多从冲、任、带、肾、肝、脾、胃经络及肝、脾、肾三脏论之;辨病因多从寒、热、湿、瘀论之;辨病性多从气滞、血瘀、寒凝、热壅论之;病势多从有余不足论之。治疗方面,多采用阴病治阳、上病下治、补虚泻实等治疗原则,并结合腧穴的近治作用、远治作用、特殊主治作用,进行选穴治疗。

关键词：针灸甲乙经妇人杂病辨证论治皇甫谧妇科病

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《外科正宗》阴阳辨证法在拔罐疗法中的应用

中国当代医药 2024年第28期31卷 118-122页

作者：万健民赵中玮苗冲甘肃医学院中医药系甘肃平凉744000

拔罐疗法作为中医特色疗法之一,目前临床尚缺辨证论治这一临床思维模式。鉴于拔罐后罐斑表现与外科疾病同样具有“外症”这一特点,同时可根据形色特征判定其病证属性,因此可将《外科正宗》中阴阳辨证学术思想引入拔罐疗法。根据罐斑的... 详细信息

拔罐疗法作为中医特色疗法之一,目前临床尚缺辨证论治这一临床思维模式。鉴于拔罐后罐斑表现与外科疾病同样具有“外症”这一特点,同时可根据形色特征判定其病证属性,因此可将《外科正宗》中阴阳辨证学术思想引入拔罐疗法。根据罐斑的颜色、形态特征,辨明疾病的寒、热、虚、实的性质,用于指导不同罐法的临床应用。罐斑的颜色有助于确定疾病的寒热属性,罐斑红紫、红黑多为热证,青白、青紫多为寒证;热证可用留罐法、刺络拔罐法清热解毒,寒证可用留罐法、闪罐法温阳散寒。罐斑的形态有助于确定疾病的虚实属性,罐斑肿势高突、消散较慢者气血充足、邪气较盛;罐斑肿势不显、消散较快者气血不足、邪气较轻。实证可用走罐泻法、刺络拔罐法祛除邪气,虚证可用走罐补法、闪罐法扶助正气。

关键词：《外科正宗》辨证论治阴阳辨证拔罐疗法

Ehd4 encodes a novel and oryza-genus-specific regulator of photoperiodic flowering in rice

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Ehd4 encodes a novel and oryza-genus-specific regulator of p...

Ketogenic diet and cancer:multidimensional exploration and research

第十四届全国植物基因组学大会

作者： He Gao Xiaoming Zheng Guilin Fei Jun Chen Mingna Jin Yulong Ren Weixun Wu Kunneng Zhou Peike Sheng Feng Zhou Ling Jiang Jie wang Xin Zhang Xiuping Guo Jiulin wang Zhijun Cheng Chuanyin Wu Haiyang wang jianmin wan National Key Laboratory for Crop Genetics and Germplasm Enhancement Jiangsu Plant Gene Engineering Research CenterNanjing Agricultural University National Key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop ScienceChinese Academy of Agricultural Sciences

Land plants have evolved increasingly complex regulatory modes of their flowering ***(Oryza sativa L.) is a short-day plant that flowers more rapidly in short-day but delays under long-day *** studies have shown that ... 详细信息

关键词： Oryza Genus rice flowering time Ehd4

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Science China Life Sciences 2025年

作者： Shiyun wan Xiaoxue Zhou Feng Xie Fangfang Zhou Long Zhang The First Affiliated Hospital the Institutes of Biology and Medical Sciences Suzhou Medical College Soochow University School of Medicine Hangzhou City University Life Sciences Institute and State Key Laboratory of Transvascular Implantation Devices of the Second Affiliated Hospital of Zhejiang University School of Medicine Zhejiang University The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors The First Affiliated Hospital Jiangxi Medical College Nanchang University Cancer Center Zhejiang University

The ketogenic diet(KD) has attracted attention in recent years for its potential anticancer effects. KD is a dietary structure of high fat,moderate protein, and extremely low carbohydrate content. Originally introduced as a treatment for epilepsy, KD has been widely applied in weight loss programs and the management of metabolic diseases. Previous studies have shown that KD can potentially inhibit the growth and spread of cancer by limiting energy supply to tumor cells, thereby inhibiting tumor angiogenesis, reducing oxidative stress in normal cells, and affecting cancer cell signaling and other processes. Moreover, KD has been shown to influence T-cell-mediated immune responses and inflammation by modulating the gut microbiota, enhance the efficacy of standard cancer treatments, and mitigate the complications of chemotherapy. However, controversies and uncertainties remain regarding the specific mechanisms and clinical effects of KD as an adjunctive therapy for cancer. Therefore, this review summarizes the existing research and explores the intricate relationships between KD and cancer treatment.

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花生种子休眠性的影响因素

核农学报 2015年第7期29卷 1392-1398页

作者：陈静江玲王春明胡晓辉翟虎渠万建民南京农业大学作物遗传与种质创新国家重点实验室/江苏省植物基因工程技术研究中心江苏南京210095 山东省花生研究所山东青岛266100 中国农业科学院北京100081 中国农业科学院作物科学研究所北京100081

为了鉴别花生品种种子休眠性差异,探讨花生种子休眠萌发机制,本研究以16个花生品种（系）为材料,进行种子休眠特性的研究。结果显示,16个品种（系）种子休眠性有差异,干种子发芽率变幅为0～100%;其中花育25号、花育28号和徐花13号干种... 详细信息

为了鉴别花生品种种子休眠性差异,探讨花生种子休眠萌发机制,本研究以16个花生品种（系）为材料,进行种子休眠特性的研究。结果显示,16个品种（系）种子休眠性有差异,干种子发芽率变幅为0～100%;其中花育25号、花育28号和徐花13号干种子发芽率为100%,强休眠品种花育52号鲜种子发芽率和干种子发芽率均为0。相同品种随成熟度增加,发芽率提高,种子休眠性下降;相同品种相同发育时期鲜种子休眠性强于干种子休眠性。内源激素分析表明,高水平内源ABA含量、低水平GA含量以及低GA/ABA比值对维持花生吸胀种子的休眠状态有积极作用。休眠态种子与乙烯利破除休眠种子相比较,乙烯利破除休眠种子的内源GA含量迅速上升,ABA含量略微下降,GA/ABA比值迅速上升。本研究为花生种子休眠及休眠解除过程中内源激素的作用提供了理论参考。

关键词：花生种子休眠性内源激素

Mutual regulation of microglia and astrocytes after Gas6 inhibits spinal cord injury

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Neural Regeneration Research 2025年第2期20卷 557-573页

作者： Jiewen Chen Xiaolin Zeng Le wang Wenwu Zhang Gang Li Xing Cheng Peiqiang Su Yong wan Xiang Li Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Guangdong Province Key Laboratory of Orthopedics and Traumatology GuangzhouGuangdong ProvinceChina

Invasive inflammation and excessive scar formation are the main reasons for the difficulty in repairing nervous tissue after spinal cord *** and astrocytes play key roles in the spinal cord injury micro-environment and share a close ***,the mechanisms involved remain *** this study,we found that after spinal cord injury,resting microglia(M0)were polarized into pro-inflammatory phenotypes(MG1 and MG3),while resting astrocytes were polarized into reactive and scar-forming *** expression of growth arrest-specific 6(Gas6)and its receptor Axl were significantly down-regulated in microglia and astrocytes after spinal cord *** vitro experiments showed that Gas6 had negative effects on the polarization of reactive astrocytes and pro-inflammatory microglia,and even inhibited the cross-regulation between *** further demonstrated that Gas6 can inhibit the polarization of reactive astrocytes by suppressing the activation of the Yes-associated protein signaling ***,in turn,inhibited the polarization of pro-inflammatory microglia by suppressing the activation of the nuclear factor-κB/p65 and Janus kinase/signal transducer and activator of transcription signaling *** vivo experiments showed that Gas6 inhibited the polarization of pro-inflammatory microglia and reactive astrocytes in the injured spinal cord,thereby promoting tissue repair and motor function ***,Gas6 may play a role in the treatment of spinal cord *** can inhibit the inflammatory pathway of microglia and polarization of astrocytes,attenuate the interaction between microglia and astrocytes in the inflammatory microenvironment,and thereby alleviate local inflammation and reduce scar formation in the spinal cord.

关键词： astrocytes Axl cell polarization Gas6 Hippo signal inflammatory micro-environment intercellular interaction microglia single-cell sequencing spinal cord injury

Preparation of Modified Composite Nanofiltration Membrane Synergistically Using Carboxylic Multi- walled Carbon Nanotube and β-cyclodextrin

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 232-239页

作者： LIU Peng MAO Junpeng FANG Yanfeng YU Yunwu CHEN Changxiu TANG Ning wan Ye GU Yaxin LIU Yunxue wanG Lihua School of Materials Science and Engineering Shenyang Jianzhu UniversityShenyang 110168China

A new modified blend ultrafiltration(UF)membrane with good hydrophilicity,high porosity and excellent anti-fouling performance was developed by using carboxylic multi-walled carbon nanotube(CMWCNT)as casting solution ***,a composite nanofiltration(NF)membrane with large water flux and good retention rate was fabricated by using the PVDF/CMWCNT blend UF membrane as the substrate,and polyvinyl alcohol(PVA),β-cyclodextrin(β-CD)and polyethylenimine(PEI)as the coating *** results show that with the appropriate addition of CMWCNT in the casting solution,the surface roughness,porosity and recovery rate of the PVDF/CMWCNT blend UF membrane is obviously *** water flux of blend UF membrane is significantly improved when the CMWCNT content increases from 0 wt%to 0.2 wt%.The water flux of blend UF membrane with 0.2 wt%CMWCNT is 162.7 L/(m^(2)·h),which is 44.3%higher than that of the pure PVDF ***β-CD content is 0.8 wt%,the retention rate of Congo red by PVDF/CMWCNT/β-CD composite NF membrane reaches 98.7%,which is 28.3%higher than that of single PVA/PEI modified *** research will provide a new idea and simple method for developing novel high-performance composite NF membranes.

关键词： CMWCNT cyclodextrin nanofiltration membrane

Assessment of future climate change impacts on water-heat-salt migration in unsaturated frozen soil using CoupModel

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Frontiers of Environmental Science & Engineering 2021年第1期15卷 145-161页

作者： Hanli wan jianmin Bian Han Zhang Yihan Li College of New Energy and Environment Jilin UniversityChangchun 130021China Key Laboratory of Groundwater Resources and Environment(Ministry of Education) Jilin UniversityChangchun 130021China

The transport mechanisms of water,heat,and salt in unsaturated frozen soil,as well as its response to future climate change are in urgent need of *** this study,western Jilin Province in north-eastern China was studied to produce a model of coupled water-heat-salt in unsaturated frozen soil using *** water,heat,and salt dynamics of unsaturated frozen soil under three representative concentration pathway(RCP)scenarios were simulated to analyze the effects of future climate change on unsaturated frozen *** results show that water,heat,and salt migration are tightly coupled,and the soil salt concentration in the surface layer(10 cm)exhibits explosive growth after freezing and *** future(2020–2099)meteorological factors in the study area were predicted using the Statistical Downscaling Model(SDSM).For RCP2.6,RCP4.5,and RCP8.5 scenarios,future temperatures during the freeze–thaw period increased by 2.68°C,3.18°C,and 4.28°C,respectively;precipitation increased by 30.28 mm,28.41 mm,and 32.17 mm,respectively;and evaporation increased by 93.57 mm,106.95 mm,and 130.57 mm,*** change will shorten the freeze–thaw period,advance the soil melting time from April to March,and enhance water and salt *** to the baseline period(1961–2005),future soil salt concentrations at 10 cm increased by 1547.54 mg/L,1762.86 mg/L,and 1713.66 mg/L under RCP2.6,RCP4.5,and RCP8.5,*** explosive salt accumulation is more *** measures should be taken to prevent the salinization of unsaturated frozen soils and address climate change.

关键词： Soil salinization Climate change Unsaturated frozen soil Water-heat-salt balance Soil environment change

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赋石水库设计功能调整方案探讨

小水电 2008年第4期 34-35页

作者：谷红卫万建民周小平安吉县水利局浙江安吉313300 安吉中盛水建有限公司浙江安吉313300

1工程概况赋石水库位于浙江省湖州市西苕溪支流西溪上游,是一座以防洪为主,结合灌溉、发电、养鱼等综合利用的大(2)型水库.控制流域面积331 km2,总库容2.18 亿m3,防洪面积25万亩,灌溉农田12.2万亩.电站装机5 400 kW,年发电量1 400万kW... 详细信息

1工程概况赋石水库位于浙江省湖州市西苕溪支流西溪上游,是一座以防洪为主,结合灌溉、发电、养鱼等综合利用的大(2)型水库.控制流域面积331 km2,总库容2.18 亿m3,防洪面积25万亩,灌溉农田12.2万亩.电站装机5 400 kW,年发电量1 400万kW·h.它和西溪另一支流南溪上的老石坎水库联合运用(2水库上游有鸭坑坞分洪渠相沟通)可控制西苕溪上游589 km2的20 a一遇全部洪水.

关键词：水库设计功能调整流域面积灌溉农田年发电量工程概况综合利用西苕溪