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Quantum public-key crypto via EPR pairs

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 58-63页

作者： Xiang-Qun Fu Hong-Wei li jian-Hong Shi Tan li wan-Su Bao Henan Key Laboratory of Quantum Information and Cryptography Information Engineering University Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of China

With the development of quantum computing technology, quantum public-key cryptography is gradually becoming an alternative to the existing classical public-key cryptography. This paper designs a quantum trapdoor one-way function via EPR pairs and quantum measurements. Based on this, a new quantum public-key cryptosystem is presented, which offers forward security,and can resist the chosen-plaintext attack and chosen-ciphertext attack. Compared with the existing quantum public-key cryptos,eavesdropping can be automatically detected in this new quantum public-key cryptosystem under a necessary condition, which is also detailed in the paper.

关键词： quantum public-key crypto trapdoor one-way function EPR pairs

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： lin-Yan Huang yi-De Zhang Jie Chen Hai-Di Fan wan wang Bin wang Ju-Yun Ma Peng-Peng li Hai-Wei Pu Xin-yian Guo jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

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World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： Xin Zhou Dan Ma yi-Xiang He Jing Jin Hong-lian wang Yun-Feng wang Fan Yang jian-Qin liu Jie Chen Zhi li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

Extraction of copper,zinc and cadmium from copper–cadmium-bearing slag by oxidative acid leaching process

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Rare Metals 2021年第10期40卷 2975-2984页

作者： Meng li ying Zhang xiao-Hui wang jian-Guang Yang Shan Qiao Shi-li Zheng yi Zhang School of Metallurgy Northeastern UniversityShenyang 110819China National Engineering Laboratory for Hydrometallurgical Cleaner Production Technology Key Laboratory of Green Process and EngineeringInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Metallurgy and Environment Central South UniversityChangsha 410083China

An intensified oxidative acid leaching of copper–cadmium-bearing slag featuring using high-efficient oxygen carrier, such as activated carbon, was investigated to achieve high leaching rate of valuable metals. The effects of leaching variables, including agitation rate, sulfuric acid concentration, temperature, slag particle size, activated carbon and cupric ion concentration, were examined. It is found that leaching rates of cadmium and zinc both exceed 99 % in a very short time, but for copper, leaching rate of 99 % is achieved under the optimized leaching parameters, which are agitation rate of 100 r·min^(-1), sulfuric acid concentration of 15 wt%, leaching temperature of 80 ℃, slag particle size of 48–75 lm, activated carbon concentration of 3 g·L^(-1),liquid-to-solid ratio of 4:1, oxygen flow rate of 0.16 L·min^(-1),and leaching time of 60 min. The macro-leaching kinetics of copper metal was analyzed, and it is concluded that the inner diffusion is the controlling step, with apparent activation energy of 18.6 kJ·mol^(-1). The leaching solution with pH value of 2–4 can be designed to selectively extract valuable metals without neutralization, and the leaching residue can be treated by prevailing Pb smelting process.

关键词： Copper–cadmium-bearing slag Catalytic oxidative acid leaching Activated carbon Kinetics

Synthesis of Novel Scolopendra-type Polydodecyloxybenzoyl[1,5]-diazocine as New Material for Optical Sensor

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Chinese Journal of Polymer Science 2018年第6期36卷 736-741页

作者： Ya-Nan liu jian-Zhong li xiao-Bo wan College of Chemistry and Pharmaceutical Sciences Qingdao Agricultural UniversityQingdao 266109China Qingdao institute of Bioprocess Technology Chinese Academy of ScienceQingdao 266101China

A new scolopendra-type polymer of polydodecyloxybenzoyl[1,5]-diazocine（PDBD） was designed and prepared using 2,5-bis（4-（dodecyloxy）-benzoyl）terephthaloyl azide with trifluoroacetic acid（TFA） via one-pot reaction in good yields. The structure of polymer was characterized using ~1 H-NMR, ^（13） C-NMR and MALDI-TOF spectra. The polymer PDBD exhibits good thermal stability as measured by TGA and DSC, and can be dissolved well in common organic solvents such as chloroform and tetrahydrofuran. In addition, UV-Vis spectral studies indicate that the polymer PDBD shows unique optical property changes（protonation/deprotonation） in the different trifluoroacetic acid environments. The new polymer is expected to be utilized as an optical functional material for fabricating optical sensors in environmental and biological fields.

关键词： Diazocine Scolopendra-type polymer Trifluoroacetic acid UV-Vis

CHARACTERIZATION OF IMPACT POLYPROPYLENE COPOLYMERS BY SOLVENT FRACTIONATION

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Chinese Journal of Polymer Science 2012年第1期30卷 122-129页

作者： xiao-ying Lu jian-jun yi Shang-tao Chen Feng-hua Zu Rong-bo li Petrochina-Petrochemical Research Institute Being 100195 China

The compositional heterogeneity of two impact polypropylene copolymers（IPCs） was studied by a combinatory investigation of temperature rising elution fractionation（TREF） and solvent *** chain structures and composition of fractions obtained from solvent fractionation were examined in *** TREF results shows that there are much more E-P segmented copolymer and more uniform distribution of ethylene sequence in IPC-1,which is responsible for its better comprehensive mechanical *** fractions from hexane and heptane are ethylene-propylene rubber phase and E-P block copolymers *** result of solvent fractionation method also shows that custom hexane or heptane extractions can not extract the E-P copolymer completely.

关键词： Fractionation Impact polypropylene copolymer Composition Chain structure

Pestaloamides A and B,two spiro-heterocyclic alkaloid epimers from the plant endophytic fungus Pestalotiopsis ***30

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Science China Chemistry 2020年第9期63卷 1208-1213页

作者： xiao-Zheng Su yi-ying Zhu jian-Wei Tang Kun Hu xiao-Nian li Han-Dong Sun Yan li Pema-Tenzin Puno State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesYunnan Key Laboratory of Natural Medicinal ChemistryKunming 650201China University of Chinese Academy of Sciences Beijing 100049China

Pestaloamides A and B(1 and 2),two novel alkaloids featuring an unprecedented spiro[imidazothiazoledione-alkylidenecyclopentenone]scaffold,were obtained from the cultures of an endophytic fungus Pestalotiopsis ***30 which inhabited the stems of Isodon *** planar structures and absolute configurations were fully determined by extensive spectroscopic analysis and X-ray *** addition,both compounds 1 and 2 showed the latent tumor immunotherapy activity through markedly promoting the cell surface engagement of NKG2 D ligands involving MICA/B and ULBP1 in HCT116 cells.

关键词： alkaloids endophytic fungus structure elucidation tumor immunotherapy

Fe_(3)O_(4)@Angelica sinensis polysaccharide nanoparticles as an ultralow-toxicity contrast agent for magnetic resonance imaging

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Rare Metals 2021年第9期40卷 2486-2493页

作者： Kai wang xiao-Guang Xu ying-li Ma Chun-Rui Sheng li-Na li li-ying Lu jian wang yi-Ning wang Yong jiang School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China School of Instrumentation Science and Optoelectronics Engineering Beihang UniversityBeijing 100191China School of Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China School of Chemistry and Biological Engineering University of Science and Technology BeijingBeijing 100083China Department of Radiology Peking Union Medical College Hospital Chinese Academy of Medical SciencesBeijing 100730China

Although iron oxide(Fe_(3)O_(4)) nanoparticles have broad application prospects as magnetic resonance imaging(MRI) contrast agent, their biocompatibility and biotoxicity still need to be improved. In this study, we prepared Fe_(3)O_(4)@Angelica sinensis polysaccharide nanoparticles(Fe_(3)O_(4)@ASP NPs) with a 9 nm Fe_(3)O_(4) core and ASP as the coating material. The Fe_(3)O_(4)@ASP NPs are superparamagnetic, can be taken up by liver and spleen macrophages in the circulatory system in vivo, and are a good-biocompatibility and low-toxicity transverse relaxation time(T_(2)) and T_(2)-star(T_(2)^(*)) magnetic resonance imaging(MRI) contrast agent for the liver. The cytotoxicity assessment using HeLa cells and the pathological tests in mice validate that Fe_(3)O_(4)@ASP NPs have low toxicity and good biocompatibility in vivo, which can be attributed to the ASP as a natural polysaccharide with good biocompatibility and its function of protecting the liver. Fe_(3)O_(4)@ASP NPs are a potential new MRI contrast agent with high signal intensity in vivo.

关键词： Superparamagnetic nanoparticles Fe_(3)O_(4) Angelica sinensis polysaccharide Magnetic resonance imaging Ultralow toxicity

Preparation and Visible-light Photocatalytic Activity of Mesoporous H_3PW_(12)O_(40)/TiO_2 Composite

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Chemical Research in Chinese Universities 2009年第6期25卷 781-785页

作者： KANG wan-li li Jin-huan HUANG jian-bin YU xiao-dan GUO yi-hang State Key Laboratory for Structural Chemistry of Unstable and Stable Species College of Chemistry and Molecular Engineering Peking University Beijing 100871 P. R. China Key Laboratory for Enhanced Oil Recovery Ministry of Education Daqing Petroleum Institute Daqing 163318 P. R. China School of Chemistry Northeast Normal University Changchun 130024 P. R. China

Wormhole-like mesostructured H3PW12O40/TiO2 composite catalyst was prepared by the combination of sol-gel chemistry and solvothermal treatment technique in the presence of a triblock copolymer surfactant. Results of Raman spectra, XRD, BJH pore distribution and TEM image indicate that the composite possess a three- dimensionally interconnected pore mesostructure with a high porosity and large pore size. Keggin units were homogeneously dispersed throughout the composite. This composite can catalyze the photodegradation of crystal violet （CV） under visible-light. The photocatalytic activity is much higher than that of pure TiO2 or H3PW12O40/TiO2 composite prepared in the absence of the surfactant.

关键词： Nanostructure Mesoporous material Photocatalysis