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血液病骨髓动态增强MRI特征的初步研究

中华肿瘤杂志 2007年第3期29卷 202-205页

作者：张蕾 catherine Mandel 杨振燕王培军 Alex G pitman 同济大学附属同济医院放射科上海200065 澳大利亚Peter Maecsllum癌症中心放射科

目的探讨血液病患者骨髓动态增强MRI（DcE-MRI）与骨髓细胞构成的关系。方法对25例恶性血液病患者进行DcE-MRI检查，测定骨髓灌注的最大强化率（PER）、最大强化斜率（Slopemax）、峰值时间（哪）和平均时间（MT）；30min后进行髂嵴穿... 详细信息

目的探讨血液病患者骨髓动态增强MRI（DcE-MRI）与骨髓细胞构成的关系。方法对25例恶性血液病患者进行DcE-MRI检查，测定骨髓灌注的最大强化率（PER）、最大强化斜率（Slopemax）、峰值时间（哪）和平均时间（MT）；30min后进行髂嵴穿刺活检，分析细胞构成。结果 25例血液病患者中，正常细胞数型骨髓20例，细胞数增多型骨髓3例，细胞数减少型骨髓2例。DcE-MRI骨髓时间．信号强度曲线（TIc）B型3例，c型7例，D型13例，E型2例。细胞数增多型骨髓PER、Slopemax均高于正常细胞数型骨髓和细胞数减少型骨髓；细胞数增多型骨髓，TTP短于正常细胞数型骨髓和细胞数减少型骨髓；细胞数减少型骨髓MT短于正常细胞数型骨髓和细胞数增多型骨髓。结论 DcE-MRI可以作为无创、有效监测血液病骨髓细胞构成变化的手段之一。

关键词：磁共振成像血液病骨髓细胞构成

Impact of Tree Stump Harvesting on Soil carbon and Nutrients and Second Rotation Tree Growth in Mid-wales, UK

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Open Journal of Forestry 2017年第1期7卷 58-78页

作者： Elena I. Vanguelova Rona pitman Sue Benham Mike Perks James I. L. Morison Forest Research Alice Holt Lodge Farnham UK

The drive to develop renewable energy is increasing the interest in energy forestry. woody biomass from forest residues has the potential to make a significant contribution to greenhouse gas emission reduction through fossil fuel substitution. However, there is a danger of operational practice running ahead of the understanding of the environmental impacts of such activities. consequently, there is an urgent requirement for scientifically underpinned guidance on the best management practices to ensure soil and water protection, including sustaining forestry’s key role in carbon capture. This study addresses the main issues associated with stump harvesting practices and their impacts on soil carbon and nutrient capital and effects on the second rotation tree growth. It reports results from a clearfell site in the UK where experimental stump harvesting was carried out in 2005 before replanting with Sitka spruce Picea sitchensis (Bon.)carr. Both stump harvested and conventional harvested areas (control) were studied in 2009 and 2010, five years after harvesting, on the two distinct soil types at the site: podzolised brown earth and peaty gley soils. Results show impacts of stump harvesting on soil carbon and nitrogen stocks, residual water, base cations (K+, ca2+ and Mg2+) concentrations and stocks and bulk density in both soil types. The organic peaty gley soil showed larger and deeper profile changes after stump harvesting compared with the podzolised brown mineral soil, where some of the negative changes in c, N and base cations in the top soil were compensated by increases at depth. Tree assessment showed positive effect of stump harvesting on K and ca uptake by young seedlings, but N and P nutrient status was reduced on the peaty gley soils. The overall results support the current UK forestry guidance for stump harvesting which identifies that soil type is the most important site factor determining the sustainability of the practice.

关键词： Forest Bioenergy Stump Harvesting Soil carbon Soil Nutrients Tree Growth UK

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金发

作者： (美)皮特曼(pitman Joanna)

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金发

A cLASS OF TESTS USING L STATISTIc FOR cONSTANT RELATIVE FAILURE RATE AGAINST MONOTONE RELATIVE FAILURE RATE

2004年

作者：（美）乔安娜·皮特曼（Joanna pitman）陈向阳徐艳译

本书从社会学、人类学、心理学、生物学等多角度，通过对古今金发女性特征的研究，通俗地阐释了对于人类种族问题的认识。

ISBN: (纸本)7806148590

本书从社会学、人类学、心理学、生物学等多角度，通过对古今金发女性特征的研究，通俗地阐释了对于人类种族问题的认识。

关键词：白色人种通俗读物

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Systems Science and Mathematical Sciences 1992年第1期5卷 19-26页

作者： K.w.chen University of North carolina charlotte NC 28223USA

In this paper we develop tests using L-statistic for constant relativefailure rate against monotone relative failure *** invariance,monotonepower and locally asymptotic power results are *** examples arepresented.

关键词： Relative failure rate L-statistic scale invariance monotone power asymptotic power pitman efficacy

Morphological and anatomical characteristics of forage peanut under shade

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Morphological and anatomical characteristics of forage peanu...

电压门控钙离子通道caV1.2促进小鼠胼胝体而非运动皮质中成年少突胶质祖细胞的存活

ⅩⅪ International Grassland congress and the Ⅷ International Rangeland congress

作者： Gobbi,K.F. Garcia,R. Garcez Neto,A.F. Ventrella,M.c. Pereira,O.G. Rocha,G.c. Federal University of Vicosa Minas GeraisBrazil

＜正＞Introduction Forage peanut（Arachis pintoi ***） is a stoloniferous legume of central *** of its shade tolerance,very high quality and high persistence under grazing,it has been suggested that forage peanut could be used in silvopastoral systems（Kretschmer ＆ pitman,2001）.This work was carried out to evaluate changes in leaf anatomy and morphological characteristics of forage peanut under shade and its acclimation to low light environment.

关键词： Arachis pintoi leaf tissues leaf stem ratio specific leaf area

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神经损伤与功能重建 2019年第12期14卷 F0003-F0003页

作者： pitman KA Ricci R Gasperini R Beasley S Pavez M charlesworth J Foa L Young KM 杜一星(编译) Menzies Institute for Medical Research University of TasmaniaHobartAustralia School of Medicine University of TasmaniaHobartAustralia 不详

在整个生命过程中,少突胶质祖细胞(OPc)增殖并分化为有髓的少突胶质细胞。OPc表达的细胞表面受体和通道,包括电压门控钙通道(VGcc),使它们能够感知并响应神经元活动。caV1.2是发育过程中OPc表达的主要L型VGcc,它能调控发育过程中OPc的... 详细信息

在整个生命过程中,少突胶质祖细胞(OPc)增殖并分化为有髓的少突胶质细胞。OPc表达的细胞表面受体和通道,包括电压门控钙通道(VGcc),使它们能够感知并响应神经元活动。caV1.2是发育过程中OPc表达的主要L型VGcc,它能调控发育过程中OPc的分化。然而,尚不清楚caV1.2是否对健康成年中枢神经系统(cNS)中的OPc行为有着相似的影响。为了研究caV1.2在成年期中的作用,我们通过对60 d的cacna1cfl/fl小鼠(对照组)和Pdgfrα-creER::cacna1cfl/fl小鼠(caV1.2敲除组)给予他莫昔芬,从而实现条件性敲除OPc中的caV1.2通道。全细胞膜片钳分析显示,caV1.2敲除使成年OPc中钙离子通过L型电压门控钙通道内流降低了约60%,这证实了它仍然是成年OPc表达的主要L型VGcc。成年OPc中条件性地敲除caV1.2,可显着提高OPc增殖能力,但不影响新产生的少突胶质细胞的数量,也不影响其形成的节间体的长度或数量。出乎意料的是,caV1.2敲除导致胼胝体中OPc的大量损失,以至于在他莫昔芬给药后7 d,caV1.2敲除小鼠的OPc密度仅为对照小鼠的约42%。OPc密度在caV1.2敲除后的2周内恢复,因为丢失的OPc被caV1.2敲除后残存的OPc所代替。OPc密度在运动皮质及脊髓中不受影响。因此我们得出结论,钙离子通过caV1.2进入细胞内对于胼胝体OPc的亚群而言是关键的生存信号,但这并非对于成熟cNS中所有OPc都是至关重要的。

关键词：电压门控钙离子通道1.2 L型钙离子通道alc亚基基因神经胶质抗原2 凋亡钙胼胝体运动皮质少突胶质细胞增殖生存电压门控钙通道