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环境与职业医学 2014年第11期31卷 875-875页

作者： Frauke Hennig Kateryna Fuks Susanne Moebus Gudrun weinmayr Michael Memmesheimer Hermann Jakobs Martina Brocker-Preuss Dagmar Führer-Sakel Stefan Mohlenkamp Raimund Erbel Karl-Heinz Jockel Barbara hoffmann

[背景]长期颗粒物空气污染（PM2.5和PM10）暴露和高交通负荷与全身性炎症标志物相关。流行病学调查主要集中于总PM,代表不同来源污染物的混合物。[目的]探讨来源特异的PM与高敏c-反应蛋白（hs-cRP,一种心血管疾病的独立预测因子）之间... 详细信息

[背景]长期颗粒物空气污染（PM2.5和PM10）暴露和高交通负荷与全身性炎症标志物相关。流行病学调查主要集中于总PM,代表不同来源污染物的混合物。[目的]探讨来源特异的PM与高敏c-反应蛋白（hs-cRP,一种心血管疾病的独立预测因子）之间的相关性。[方法]采用Heinz Nixdorf回忆研究（Heinz Nixdorf Recall study）中第一次（2000—2003年）和第二次（2006—2008年）的检测数据。Heinz Nixdorf回忆研究是一项在德国进行的、以人群为基础的前瞻性队列研究,初始参加者为4 814人（45~75岁）。利用化学传输模型估计参加者的住宅局部交通和行业特异性细颗粒物（PM2.5）长期暴露的状况。使用线性混合模型,以参与者作为随机截距,来估计特定来源的PM与hs-cRP水平的自然对数变换值之间的关联,并设置年龄、性别、教育程度、体质指数、低和高密度脂蛋白胆固醇、吸烟变量、体力活动、季节、湿度和城市等因素的对照（总共8 204名观察对象）。[结果]总PM2.5每增加1μg/m3与血清hs-cRP浓度增加4.53%相关（95%cI：2.76%~6.33%）。交通和行业特异性的PM2.5增加1μg/m3分别与血清hs-cRP升高17.89%（95%cI：7.66%~29.09%）和7.96%（95%cI：3.45%~12.67%）相关。PM10具有相似的关联性。[结论]与总PM相比,长期局部交通特异性PM（PM2.5,PM10）暴露与全身性炎症反应的相关性更强。全身性炎症反应与局部行业特异性PM的关联比与总PM的关联稍强,但二者无显著性差异。

关键词：空气污染全身性炎症反应特异性关联比线性混合模型交通负荷对数变换细颗粒物流行病学调查炎症标志物

新型轴向磁场电机Dynax在汽车动力系统中的控制和运行

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电力电子 2011年第6期9卷 41-43页

作者： A.Kleimaier B.hoffmann 齐丽英周明磊王琛琛 compact Dynamics GmbH Moosstrasse 9 D-82319 StarnbergGermany 北京交通大学

Dynax是一种由永磁体转子和带轴向绕组的爪极式定子组成的电机。其中含永磁体镀层的玻璃纤维转子属于首创,其并未使用护铁。该电机可以显著提高输出转矩并扩展电机的速度运行范围。它具有比较高的漏感和低短路电流,从而使其在宽速度范... 详细信息

Dynax是一种由永磁体转子和带轴向绕组的爪极式定子组成的电机。其中含永磁体镀层的玻璃纤维转子属于首创,其并未使用护铁。该电机可以显著提高输出转矩并扩展电机的速度运行范围。它具有比较高的漏感和低短路电流,从而使其在宽速度范围内的弱磁运行成为可能。由于其典型的极对数多的特点,逆变器和电机的控制需承受较高的基波频率。本文对其优点,特别是在交流起动机和电动汽车中的应用作了着重介绍,同时也介绍了在电机控制中的一些特殊要求。

关键词：磁场电机汽车动力系统基波频率

Room-temperature multiple ligands-tailored SnO_(2) quantum dots endow in situ dual-interface binding for upscaling efficient perovskite photovoltaics with high V_(Oc)

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Light(Science & Applications) 2021年第12期10卷 2467-2481页

作者： Zhiwei Ren Kuan Liu Hanlin Hu Xuyun Guo Yajun Gao Patrick w.K.Fong Qiong Liang Hua Tang Jiaming Huang Hengkai Zhang Minchao Qin Li cui Hrisheekesh Thachoth chandran Dong Shen Ming-Fai Lo Annie Ng charles Surya Minhua Shao chun-Sing Lee Xinhui Lu Frédéric Laquai Ye Zhu Gang Li Department of Electronic and Information Engineering Research Institute for Smart Energy(RISE)Guangdong-Hong Kong-Macao(GHM)Joint Laboratory for Photonic-Thermal-Electrical Energy Materials and DevicesThe Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Department of Electrical and computer Engineering Nazarbayev UniversityNur-SultanKazakhstan The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057China hoffmann Institute of Advanced Materials Shenzhen Polytechnic7098 Liuxian BoulevardShenzhen 518055China Department of Applied Physics The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Department of chemical and Biological Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina King Abdullah University of Science and Technology(KAUST) KAUST Solar Center(KSC)Physical Sciences and Engineering Division(PSE)Material Science and Engineering Program(MSE)Thuwal 23955-6900Kingdom of Saudi Arabia Department of Physics The Chinese University of Hong KongShatin 999077 Hong KongChina center of Super-Diamond and Advanced Films(cOSDAF) Department of ChemistryCity University of Hong KongHong KongChina

The benchmark tin oxide(SnO_(2))electron transporting layers(ETLs)have enabled remarkable progress in planar perovskite solar cell(PScs).However,the energy loss is still a challenge due to the lack of“hidden interface”*** report a novel ligand-tailored ultrafine SnO_(2) quantum dots(QDs)via a facile rapid room temperature ***,the ligand-tailored SnO_(2) QDs ETL with multi-functional terminal groups in situ refines the buried interfaces with both the perovskite and transparent electrode via enhanced interface binding and perovskite *** novel ETLs induce synergistic effects of physical and chemical interfacial modulation and preferred perovskite crystallization-directing,delivering reduced interface defects,suppressed non-radiative recombination and elongated charge carrier *** conversion efficiency(PcE)of 23.02%(0.04 cm^(2))and 21.6%(0.98 cm^(2),V_(Oc) loss:0.336 V)have been achieved for the blade-coated PScs(1.54 eV E_(g))with our new ETLs,representing a record for SnO_(2) based blade-coated ***,a substantially enhanced PcE(V_(Oc))from 20.4%(1.15 V)to 22.8%(1.24 V,90 mV higher V_(Oc),0.04 cm^(2) device)in the blade-coated 1.61 eV PScs system,via replacing the benchmark commercial colloidal SnO_(2) with our new ETLs.

关键词： perovskite interface quantum

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肌营养不良患者的梭内肌纤维功能保留

世界核心医学期刊文摘（神经病学分册） 2005年第10期1卷 45-46页

作者： Aimonetti J.-M. Ribot-ciscar E. Rossi-Durand c. 陈海 Laboratoire de Neurobiologie Humaine Universit' e de Provence- CNRS Centre de Saint- Charles 3 Place Victor Hugo 13331 Marseille France Dr.

In a previous study, we showed that patients with muscular dystrophies (MDs) perceive passive movements, experience sensations of illusory movement induced b y muscle tendon vibration, and have proprioceptive- regulated sways in response to vibratory stimulation applied to the neck and ankle muscle tendons. These fi ndings argue for preserved proprioceptive functions of muscle spindles. However, it is unclear whether the function of intrafusal muscle fibers is spared, i.e., whether they retain their ability to contract when submitted to a fusimotor dri ve. To answer this question, we analyzed the effects of reinforcement maneuvers (mental computation and the Jendrassik maneuver) that are known to increase musc le spindle sensitivity via fusimotor drive in healthy subjects. Nine patients wi th different MDs participated in the study. Reinforcement maneuvers increased bo th the mean amplitude of the Achilles tendon reflex (187 ± 52.9% of the mean control amplitude) and the sensitivity of muscle spindle afferents to imposed mo vements of the ankle. The same reinforcement maneuvers failed to alter the ampli tude of the hoffmann reflex in the triceps surae muscle. These results suggest t hat the intrafusal muscle fibers preserve their contractile abilities in slowly progressive MDs. The reasons for a differential impairment of intrafusal and ext rafusal muscle fibers and the clinical implications of the present results are d iscussed.

关键词：肌营养不良梭内肌纤维强化操作复合运动肌梭健康受试者动反应收缩能力小腿三头肌强迫运动

儿童早期空气污染与呼吸道感染:EScAPE项目中10个欧洲出生队列的分析

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环境与职业医学 2014年第3期31卷 202-202页

作者： Elaina A.MacIntyre Ulrike Gehring Anna Molter Elaine Fuertes claudia Klümper Ursula Kramer Ulrich Quass Barbara hoffmann Mireia Gascon Bert Brunekreef Gerard H.Koppelman Rob Beelen Gerard Hoek Matthias Birk Johan c.de Jongste H.A.Smit Josef cyrys Olena Gruzieva Michal Korek Anna Bergstrom Raymond M.Agius Frank de Vocht Angela Simpson Daniela Porta Francesco Forastiere chiara Badaloni Giulia cesaroni Ana Esplugues Ana Fernández-Somoano Aitana Lerxundi Jordi Sunyer Marta cirach Mark J.Nieuwenhuijsen Goran Pershagen Joachim Heinrich

[背景]将交通源空气污染作为幼儿期呼吸道感染的危险因素的研究很少。[目的]在10个欧洲出生队列——BAMSE（瑞典）、GASPⅡ（意大利）、GINIplus和LISAplus（德国）、MAAS（英国）、PIAMA（荷兰）和4个INMA队列（西班牙）——中研究空... 详细信息

[背景]将交通源空气污染作为幼儿期呼吸道感染的危险因素的研究很少。[目的]在10个欧洲出生队列——BAMSE（瑞典）、GASPⅡ（意大利）、GINIplus和LISAplus（德国）、MAAS（英国）、PIAMA（荷兰）和4个INMA队列（西班牙）——中研究空气污染与肺炎、哮喘及中耳炎之间的相关性，并使用meta分析得出综合效应估值。[方法]评价家长报告的医师诊断的儿童早期肺炎、中耳炎以及哮喘与全年平均污染物水平[二氧化氮（NO2）、氮氧化物（NOx）、≤2．5gm的颗粒物（PM2.5）、PM2.5吸光度、PM10、PM2.5-10（粗PM）]间的关联，污染物浓度的估计采用土地利用回归模型并根据孩子的出生住址分配。作为EScAPE项目的一部分，每个研究区域都采用相同的方案建立回归模型。用logistic回归来计算每个研究校正后的效应估值，用随机效应meta分析来计算合并的估计值。[结果]除了PM2.5外的所有污染物，肺炎的合并校正优势比（OR）均升高（例如，N02每增加10μg／m3，OR=1．30，95％cI：1．02～1．65；PM10每增加10μg／m3的OR=1．76，95％cI：1．00—3．09）。对于中耳炎和哮喘，除了NO2与中耳炎问的关联（每10μg／m3对应的OR=1．09，95％cI：1．02～1．16），所有分析的结果均无显著性。[结论]对EScAPE项目中10个欧洲出生队列进行的meta分析为空气污染和儿童早期肺炎之间的相关性找到一致性的证据，也为与中耳炎间的相关性找到了一些证据。

关键词：早期肺炎呼吸道感染出生队列空气污染欧洲儿童 meta分析 logistic

Decline in subarachnoid haemorrhage volumes associated with the first wave of the cOVID- 19 pandemic

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Stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N Nguyen Diogo c Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi chandril chugh charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke watanabe Dong Hun Shin Pedro Sc Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne weeks Elena A cora Rotem Sivan-hoffmann Roberto crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory walker Eiji Hagashi Steve M cordina Hong Gee Roh Ken wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y wu Simon John Alex Brehm Marios Psychogios william J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen winters Johnny wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA Radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt Radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance Stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of Radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the cOVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** we conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and cOVID-19 were identified by prospective aneurysm databases or by International classification of Diseases,10th Revision,*** 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%cI−24.3%to−20.7%,pclined with 1170-1035 procedures,respectively,representing an 11.5%(95%cI−13.5%to−9.8%,p=0.002)relative *** analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%cI−28.0%to−22.1%,pcrease in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%cI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this *** There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the cOVID-19 *** findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid

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4-二甲氨基吡啶(DMAP)的合成研究

西南民族大学学报（自然科学版） 2004年第4期30卷 425-428页

作者：廖戎万积秋袁晓静西南民族大学化学与环境保护工程学院成都610041 四川省化工研究设计院成都610000

综述了高效酰化催化剂4-二甲氨基吡啶(DMAP)的合成方法及应用前景.在比较现有合成条件的基础上,采用异烟酸为原料,经酰化、霍夫曼降解、重氮化、二甲胺化的路线来制取DMAP,并对反应条件、操作流程作了一系列的探索.

关键词：催化剂 4-二甲氨基吡啶(DMAP) 合成

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嗅鞘细胞移植治疗额颞叶痴呆1例

中国组织工程研究与临床康复 2007年第20期11卷 4038-4040页

作者：江昭黄红云陈琳郗海涛张峰刘彦铖刘瑞文姜超北京市虹天济神经科学研究院北京市西山医院暨北京康复中心神经外科北京市100041

目的:观察人胚胎嗅鞘细胞移植治疗额颞叶痴呆的有效性。方法:选择2006-04-04于北京市虹天济神经科学研究院和北京市西山医院暨北京康复中心神经外科就诊患者1例,男性,57岁,因“行为异常,性格及言语改变2年4个月”入院。患者知情同意并... 详细信息

目的:观察人胚胎嗅鞘细胞移植治疗额颞叶痴呆的有效性。方法:选择2006-04-04于北京市虹天济神经科学研究院和北京市西山医院暨北京康复中心神经外科就诊患者1例,男性,57岁,因“行为异常,性格及言语改变2年4个月”入院。患者知情同意并签署知情同意书。入院查体双侧hoffmann征可疑阳性,双侧Babinski征未引出。头颅MRI示双侧额颞叶脑沟、侧裂池增宽,脑实质萎缩明显,诊断为额颞叶痴呆。局麻下对患者进行人胚胎嗅鞘细胞移植术,于双侧额叶放射冠位置分别注射人胚胎嗅鞘细胞约100万个。移植前后使用日常生活活动量表评价患者神经功能。量表包括吃饭、穿衣、购物等20个日常行为活动项目。评分分4级:1级-可由自己完成,无困难;2级-完成有些困难;3级,需要帮助;4级-能力丧失,根本无法完成;如受试者从未做过的项目或无从了解的项目,则记为9,不计入总分。总分20分为正常;>20分为功能低下。结果:术后无任何并发症及不良反应。移植术后3周患者情感、认知方面有所改善。日常生活活动量表与术前比较,分数由43分下降至32分。术后6周电子邮件随访,神经功能继续改善。结论:人胚胎嗅鞘细胞移植后近期可部分改善额颞叶痴呆患者神经系统功能,提高生活质量,其恢复机制和长期效果有待进一步观察。

关键词：痴呆嗅鞘细胞移植