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water-induced physicochemical and pore changes in limestone for surrounding rock across pressure aquifers

Journal of Mountain Science 2024年第9期21卷 3186-3200页

作者： wU Daguo PENG Jianhe xia Zhenzhao School of Civil and Hydraulic Engineering Hefei University of TechnologyHefei 230009China Anhui and Huaihe River Institute of Hydraulic Research Hefei 230088China School of Civil and Hydraulic Engineering Huazhong University of Science and TechnologyWuhan 430074China

Osmotic water alters the physicochemical properties and internal structures of *** issue is particularly critical in tunnel construction across mountainous regions with aquifers,where pressurized groundwater can destabilize the limestone-based surrounding ***,systematic research into the physicochemical properties and pore structure changes in the limestone under pressurized water is ***,it is essential to develop an interpretable mathematical model to accurately depict how pressurized osmotic water weakens *** this research,a specialized device was designed to simulate the process of osmotic laminar flow within ***,four main tests were conducted:mass loss,acoustic emission(AE),mercury intrusion porosimetry(MIP),and fluorescence *** results gained from tests led to the development of a“Particle-pore throat-water film”*** model explains water-induced physicochemical and pore changes in limestone under osmotic pressure and reveals evolutionary mechanisms as pressure *** on experimental results and model,we found that osmotic pressure not only alters limestone composition but also affects pore throats larger than 0.1μ***,osmotic pressure expands pore throats,enhancing pore structure uniformity,interconnectivity,and *** effects are observed at a threshold of 7.5 MPa,where cohesive forces within the mineral lattice are surpassed,leading to the breakdown of erosion-resistant layer and a significant increase in hydrochemical erosion.

关键词： water rock reaction Geochemistry Osmotic pressure Pore scale study Limestone Pressure aquifer

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Formation Characteristics of CO_(2) Hydrates in the Presence of Porous Media and NaCl

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China Petroleum Processing & Petrochemical Technology 2024年第2期26卷 168-177页

作者： Han Jianchao Zhu Shuai Gui xia College of Chemical Engineering Nanjing Tech UniversityNanjing 211816China

Hydrate-based CO_(2) sequestration is an effective method for reducing the greenhouse effect,and the presence of porous media and NaCl can impact the formation characteristics of *** study uses the constant volume temperature search method to investigate the effects of quartz sand particle size(0.006‒0.03 mm),water saturation(30%–90%),and NaCl concentration(1%‒9%)on the phase equilibrium and kinetics of CO_(2) hydrates within a temperature range of 273‒285 K and pressure range of 1.0‒3.5 *** results indicate that a decrease in quartz sand particle size or an increase in NaCl concentration shifts the hydrate phase equilibrium curve towards lower temperatures and higher pressures,making hydrate generation conditions more *** different particle size systems,there are no significant changes in the rate of CO_(2) hydrate formation or conversion *** highest hydrate conversion rate of 71.1%is observed in a 0.015 mm particle size *** increasing water saturation,both the generation rate and conversion rate of CO_(2) hydrates show a trend of first increasing and then ***,low concentrations of NaCl(1%–3%)are found to enhance the formation and conversion rates of CO_(2) ***,as NaCl concentration increases,the rate of CO_(2) hydrate formation and conversion rate decrease.

关键词： CO_(2)hydrate porous medium NaCl formation characteristics

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Consequences of Rényi entropy on the thermal geometries and Hawking evaporation of topological dyonic dilaton black hole

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Communications in Theoretical Physics 2024年第2期76卷 102-110页

作者： Muhammad Yasir xia Tiecheng Muhammad Usman Shahid Chaudhary Department of Mathematics Shanghai University and Newtouch Center for Mathematics of Shanghai UniversityShanghai200444China Department of Natural Sciences and Humanities University of Engineering and Technology LahoreNew CampusPakistan

The thermodynamics of black holes(BHs)has had a profound impact on theoretical physics,providing insight into the nature of gravity,the quantum structure of spacetime and the fundamental laws governing the *** this study,we investigate thermal geometries and Hawking evaporation of the recently proposed topological dyonic dilaton BH in anti-de Sitter(Ad S)*** consider Rényi entropy and obtain the relations for pressure,heat capacity and Gibbs free energy and observe that the Rényi parameter and dilaton field play a vital role in the phase transition and stability of the ***,we use weinhold,Ruppeiner and Hendi Panahiyah Eslam Momennia models to evaluate the scalar curvature of the BH and find out that the divergence points of the scalar curvature coincides with the zero of specific ***,using Stefan–Boltzmann law,we determine that the BH without a dilaton field evaporates far more quickly compared to the dilaton BH in Ad S space.

关键词： topological dyonic dilaton black hole phase transition thermal geometry Hawking evaporation

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Potential of arbuscular mycorrhizal fungi for soil health:A review

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Pedosphere 2024年第2期34卷 279-288页

作者： Junling ZHANG Ruotong ZHAO xia LI Jiangzhou ZHANG College of Resources and Environmental Sciences National Academy of Agriculture Green DevelopmentKey Laboratory of Plant-Soil InteractionsMinistry of EducationChina Agricultural UniversityBeijing 100193China College of Agronomy and Life Science Shanxi Datong UniversityDatong 037009China College of Resources and Environment/International Magnesium Institute Fujian Agriculture and Forestry UniversityFuzhou 350002China

Soil health is an important component of“One Health”.Soils provide habitat to diverse and abundant *** microbial diversity and functions is essential for building healthy soils towards sustainable *** mycorrhizal fungi(AMF)form potentially symbiotic associations with approximately 80%of land plant species that are well recognized for carbon flux and nutrient *** addition to disentangling the signaling pathways and regulatory mechanisms between the two partners,recent advances in hyphosphere research highlight some emerging roles of AMF and associated microbes in the delivery of soil *** paper reviews the contribution of AMF to soil health in agroecosystems,with a major focus on recent progress in the contribution of hyphosphere microbiome to nutrient cycling,carbon sequestration,and soil *** hyphosphere microbiome and fungal stimulants open avenues for developing new fertilizer formulas to promote AMF *** practice,developing AMF-friendly management strategies will have long-term positive effects on sustainable agriculture aiming at simultaneously providing food security,increasing resource use efficiency,and maintaining environment integrity.

关键词： arbuscular mycorrhizal fungi-friendly management strategies carbon sequestration hyphosphere microbiome nutrient cycling soil aggregation soilfunctions

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Microbiome and intestinal pathophysiology in post-acute sequelae of COVID-19

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Genes & Diseases 2024年第3期11卷 220-231页

作者： Jilei Zhang Yongguo Zhang Yinglin xia Jun Sun Division of Gastroenterology and Hepatology Department of MedicineUniversity of Ilinois ChicagoIL60612USA Uic Cancer Center Department of Microbiology and ImmunologyUniversity of Ilinois ChicagoChicagoIL60612USA Jesse Brown VA Medical Center ChicagoIL60612USA

Long CoVID,also known for post-acute sequelae of CovID-19,describes the people who have the signs and symptoms that continue or develop after the acute coviD-19 *** CovID patients suffer from an inflammation or host responses towards the virus approx-imately 4 weeks after initial infection with the SARS CoV-2 virus and continue for an unchar-acterized *** infected with CovID-19 before could experience long-CcovID conditions,including the patients who were infected with SARS CoV-2 virus confirmed by tests and those who never knew they had an infection *** with long CoviD may experience health problems from different types and combinations of symptoms over time,such as fa-tigue,dyspnea,cognitive impairments,and gastrointestinal(Gl)symptoms(e.g.,nausea,vom-iting,diarrhea,decreased or loss of appetite,abdominal pain,and dysgeusia).The critical role of the microbiome in these Gl symptoms and long CovID were reported in clinical patients and experimental ***,we provide an overall view of the critical role of the Gl tract and microbiome in the development of long COVID,including the clinical Gl symptoms in patients,dysbiosis,viral-microbiome interactions,barrier function,and inflammatory bowel disease patients with long *** highlight the potential mechanisms and possible treatment based on Gl health and ***,we discuss challenges and future direction in the long CoVID clinic and research.

关键词： Gastrointestinal symptoms Gl tract Gut microbiome Inflammatorybowel diseases Intestinal barrier Long CoVID Metabolites Tight junctions

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Security-Enhanced Directional Modulation Based on Two-Dimensional M-wFRFT

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China Communications 2024年第5期21卷 229-248页

作者： Zhou Zhuang Luo Junshan wang Shilian xia Guojiang School of Electronic Science National University of Defense TechnologyChangsha 410073China Beijing Institute of Astronautical Systems Engineering Beijing 100076China

Directional modulation(DM)is one of the most promising secure communication ***,when the eavesdropper is co-located with the legitimate receiver,the conventional DM has the disadvantages of weak anti-scanning capability,anti-deciphering capability,and low secrecy *** response to these problems,we propose a twodimensional multi-term weighted fractional Fourier transform aided DM scheme,in which the legitimate receiver and the transmitter use different transform terms and transform orders to encrypt and decrypt the confidential *** order to further lower the probability of being deciphered by an eavesdropper,we use the subblock partition method to convert the one-dimensional modulated signal vector into a twodimensional signal matrix,increasing the confusion of the useful *** results demonstrate that the proposed DM scheme not only provides stronger anti-deciphering and anti-scanning capabilities but also improves the secrecy rate performance of the system.

关键词： bit error rate directional modulation phased array secrecy rate weighted fractional Fourier transform

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Improved STNModels and Heuristic Rules for Cooperative Scheduling in Automated Container Terminals

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1637-1661页

作者： Hongyan xia Jin Zhu Institute of Logistics Science and Engineering Shanghai Maritime UniversityShanghai201306China

Improving the cooperative scheduling efficiency of equipment is the key for automated container terminals to copewith the development trend of large-scale ships. In order to improve the solution efficiency of the existing spacetimenetwork (STN) model for the cooperative scheduling problem of yard cranes (YCs) and automated guidedvehicles (AGVs) and extend its application scenarios, two improved STN models are proposed. The flow balanceconstraints in the original model are decomposed, and the trajectory constraints of YCs and AGVs are added toacquire the model STN_A. The coupling constraint in STN_A is updated, and buffer constraints are added toSTN_A so that themodel STN_B is *** the size of the problem increases, the solution speed of CPLEX becomesthe bottleneck. So a heuristic method containing three groups of heuristic rules is designed to obtain a near-optimalsolution quickly. Experimental results showthat the computation time of STN_A is shortened by 49.47% on averageand the gap is reduced by 1.69% on average compared with the original model. The gap between the solution ofthe heuristic rules and the solution of CPLEX is less than 3.50%, and the solution time of the heuristic rules is onaverage 99.85% less than the solution time of CPLEX. Compared with STN_A, the computation time for solvingSTN_B increases by 58.93% on average.

关键词： Automated container terminal buffer cooperative scheduling heuristic rules space-time network

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Targeting RAF dimers in RAS mutant tumors:From biology to clinic

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Acta Pharmaceutica Sinica B 2024年第5期14卷 1895-1923页

作者： Huanhuan Yin Qiulin Tang Hongwei xia Feng Bi Division of Abdominal Cancer Department of Medical OncologyCancer Center and Laboratory of Molecular Targeted Therapy in OncologyWest China HospitalSichuan UniversityChengdu 610041China

RAS mutations occur in approximately 30%of tumors worldwide and have a poor prognosis due to limited *** targeting of KRAS G12C has achieved significant success in recent years,but there is still a lack of efficient therapeutic approaches for tumors with non-G12C KRAS mutations.A highly promising approach is to target the MAPK pathway downstream of RAS,with a particular focus on RAF ***-generation RAF inhibitors have been authorized to treat BRAF mutant tumors for over a ***,their use in RAS-mutated tumors is not recommended due to the paradoxical ERK activation mainly caused by RAF *** address the issue of RAF dimerization,type II RAF inhibitors have emerged as leading *** clinical studies have shown the initial effectiveness of these agents against RAS mutant ***,type II RAF inhibitors in combination with MEK or ERK inhibitors have demonstrated impressive efficacy in RAS mutant *** review aims to clarify the importance of RAF dimerization in cellular signaling and resistance to treatment in tumors with RAS mutations,as well as recent progress in therapeutic approaches to address the problem of RAF dimerization in RAS mutant tumors.

关键词： RAS mutations RAF dimerization RAF inhibitors Cancer therapy Drug resistance

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wetting-drying effect on the strength and microstructure of cementphosphogypsum stabilized soils

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第3期16卷 1049-1058页

作者： Lingling Zeng xia Bian Jiaxing weng Tao Zhang College of Civil Engineering Zhejiang University of TechnologyHanzhou310014China Key Laboratory of Ministry of Education for Geomechanics and Embankment Engineering Hohai UniversityNanjing210098China State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyXuzhou221116China Jiangsu water Source Company Ltd.of the Eastern Route of the South-to-North water Diversion Project Nanjing210000China Power China Zhongnan Engineering Corporation Limited Changsha410027China

Phosphogypsum has often been used as an effective and environmentally friendly binder for partial replacement of cement,improving the engineering properties of slurries with high water ***,the influence of phosphogypsum on the physicomechnical properties of stabilized soil subjected to wettingedrying cycles is not well understood to *** this study,the effect of phosphogypsum on the durability of stabilized soil was studied by conducting a series of laboratory experiments,illustrating the changes in mass loss,pH value and unconfined compressive strength(qu)with wettingdrying *** test results showed that the presence of phosphogypsum significantly restrained the mass loss in the early stage(lower than the 4th cycle),which in turn led to a higher qu of stabilized soil than that without *** the 4th cycle,a sudden increase in mass loss was observed for stabilized soil with phosphogypsum,resulting in a significant drop in qu to a value lower than those without phosphogypsum at the 6th *** addition,the qu of stabilized soils correlated well with the measured soil pH irrespective of phosphogypsum content for all wettingedrying *** to the microstructure observation via scanning electron microscope(SEM)and X-ray diffraction(XRD)tests,the mechanisms relating the sudden loss of qu for the stabilized soils with phosphogypsum after the 4th wetting-drying cycle are summarized as follows:(i)the disappearance of ettringite weakening the cementation bonding effect,(ii)the generation of a larger extent of microcrack,and(iii)a lower pH value,in comparison with the stabilized soil without phosphogypsum.

关键词： wetting-drying Phosphogypsum Microstructure Durability

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Resveratrol combats chronic diseases through enhancing mitochondrial quality

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Food Science and Human wellness 2024年第2期13卷 597-610页

作者： weichu Tao Hu Zhang xia Jiang Ning Chen Tianjiu Research and Development Center for Exercise Nutrition and Foods Hubei Key Laboratory of Exercise Training and MonitoringCollege of Sports MedicineWuhan Sports UniversityWuhan 430079China The University Hospital of wuhan Sports University Wuhan 430079China

Resveratrol(RSV),as a functional food component extracted from natural plants,has been widely studied and recognized in preventing and treating various diseases,with major mechanisms including executing anti-inflammation and anti-oxidation functions,and improving mitochondrial *** diseases as non-communicable diseases are mainly caused by multiple factors,such as physiological decline and dysfunction in the body,and have become a significant challenge on public health *** is worth noting that chronic diseases such as Alzheimer's disease(AD),Parkinson's disease(PD),muscle atrophy,cardiovascular disease,obesity,and cancer are accompanied by abnormal mitochondrial ***,targeted regulation of mitochondria may be a meaningful way to prevent and treat chronic *** evidence has confirmed that RSV is actively involved in regulating mitochondria,and it has become an essential consideration to prevent and treat chronic diseases through targeting mitochondria and improving corresponding *** this article,current studies on RSV to optimize mitochondrial quality for preventing and alleviating chronic disease are systematically summarized,which can provide a theoretical reference for the development of functional foods or drugs to combat chronic diseases.

关键词： Resveratrol Functional food Mitochondrial quality Chronic disease Anti-inflammation Anti-oxidation

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