检索结果-南通市图书馆

Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt

world Journal of Gastroenterology 2016年第25期22卷 5780-5789页

作者： Edward wolfgang lee andrew Kuei Sammy Saab Ronald w Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin p Mc williams Stephen T Kee Department of Radiology Division of Interventional Radiology Ronald Reagan Medical Center at UCLA David Geffen School of Medicine at UCLA Department of Medicine Division of Hepatology Pfleger Liver Institute University of California at Los Angeles Dumont-UCLA Transplant Center Pfleger Liver Institute Division of Liver and Pancreas Transplantation Department of Surgery David Geffen School of Medicine at University of California Los Angeles

AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt (TIpS) in 15 ***: Using the National Inpatient Sample which is a part of Health Cost and Utilization project, we identified a discharge-weighted national estimate of 83884 TIpS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and ***: Overall, 12.3% of patients died during hospitalization with downward trend in-hospital mortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients (OR = 1.809 vs Caucasian patients, p patients (OR = 1.347 vs non-transferred, p p patients in the Northeast region (OR = 1.449 vs west, p pital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death (OR = 1.249 per one increase in number of procedures). patients diagnosed with acute respiratory failure (OR = 8.246), acute kidney failure (OR = 4.359), hepatic encephalopathy (OR = 2.217) and esophageal variceal bleeding (OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites (OR = 0.136, p with the highest odds of in-hospital death were fluid and electrolyte disorders (OR = 2.823), coagulopathy (OR = 2.016), and lymphoma (OR = 1.842).CONCLUSION: The overall mortality of the TIpS procedure is stea

关键词： Transjugular intrahepatic portosystemic shunt Mortality Inpatient United States National Inpatient Sample database Health Cost and Utilization project

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

predicting intensity of white-tailed deer herbivory in the Central Appalachian Mountains

引用

Journal of Forestry Research 2018年第3期29卷 830-839页

作者： andrew B.Kniowski w.Mark Ford Department of Fish and wildlife Conservation Virginia Tech U.S. Geological Survey Virginia Cooperative Fish and Wildlife Research Unit Virginia Tech

In eastern North America, white-tailed deer(Odocoileus virginianus) can have profound influences on forest biodiversity and forest successional *** to high deer populations in the central Appalachians have resulted in lower forest *** effects in some areas persist even following deer population reductions or declines. This has prompted managers to consider deer population management goals in light of policies designed to support conservation of biodiversity and forest regeneration while continuing to support ample recreational hunting opportunities. However,despite known relationships between herbivory intensity and biodiversity impact, little information exists on the predictability of herbivory intensity across the varied and spatially diverse habitat conditions of the central Appalachians. we examined the predictability of browsing rates across central Appalachian landscapes at four environmental scales: vegetative community characteristics, physical environment, habitat configuration, and local human and deer population demographics. In an information-theoretic approach, we found that a model fitting the number of stems browsed relative to local vegetation characteristics received most(62%) of the overall support of all tested models assessing herbivory impact. Our data suggest that deer herbivory responded most predictably to differences in vegetation quantity and type. No other spatial factors or demographic factors consistently affected browsing intensity. Because herbivory, vegetation communities, and productivity vary spatially, we suggest that effective broad-scale herbivory impact assessment should include spatially-balanced vegetation monitoring that accounts for regional differences in deer forage *** monitoring is necessary to avoid biodiversity impacts and deleterious changes in vegetation community composition that are difficult to reverse and/or may not be detected using traditional deer-density based

关键词： Biodiversity Central Appalachian Mountains Herbivory Odocoileus virginianus predicting browsing intensity white-tailed deer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bacillary layer detachment presenting with posterior scleritis:case report

引用

Annals of Eye Science 2022年第3期7卷 67-71页

作者： Gregory w.Bligard andrew R.lee Lynn M.Hassman Department of Ophthalmology and Visual Sciences Washington University in St.Louis School of MedicineSt.LouisMOUSA

Background:Bacillary layer detachment(BALAD)is a phenomenon characterized by fluid accumulation at the myoid region of the inner photoreceptor segments identifiable on optical coherence tomography(OCT)*** finding has been recently described in patients with diverse primary diagnoses which share the common feature of serous exudation in the posterior ***,thus far there have been very few reports in the literature of BALAD in patients with posterior *** Description:A 16-year-old male presented with unilateral vision changes that acutely worsened overnight to significant unilateral vision *** was eventually diagnosed with idiopathic posterior scleritis with associated BALAD on *** to other reported cases of BALAD,he experienced anatomic restoration of the outer retina followed by good visual recovery after treatment with high dose steroid,ultimately with complete recovery of both retinal anatomy and vision within 4 ***:This case provides further evidence that posterior scleritis can be a cause of *** rapid presentation and excellent visual and anatomical outcome of this case is entirely consistent with known descriptions of BALAD in a variety of other conditions,further supporting the categorization of BALAD as an entity which retinal specialists should be able to recognize as distinct from other forms of intraretinal fluid,retinal detachment,and retinoschisis.

关键词： Case report bacillary layer detachment(BALAD) photoreceptor scleritis inner segment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessing the impact of arthropod natural enemies on crop pests at the field scale

引用

Insect Science 2015年第1期22卷 20-34页

作者： Sarina Macfadyen andrew p. Davies Myron p. Zalucki CSIRO Agriculture Flagship Clunies Ross St Acton ACT2601 Australia CSIRO Australian Cotton Research Institute (ACRI) NarrabriNSW 2390 Austrafia School of Biological Sciences University of Queensland St Lucia Brisbane QLD 4072 Australia

There are many reasons why it is important that we find ways to conserve, and better utilize natural enemies of invertebrate crop pests. Currently, measures of natural enemy impact are rarely incorporated into studies that purport to examine pest control. Most studies examine pest and natural enemy presence and/or abundance and then qualitatively infer impact. while this provides useful data to address a range of ecological questions, a measure of impact is critical for guiding pest management decision-making. Often some very simple techniques can be used to obtain an estimate of natural enemy impact. we present examples of field-based studies that have used cages, barriers to restrict natural enemy or prey movement, direct observation of natural enemy attack, and sentinel prey items to estimate mortality. The measure of natural enemy impact used in each study needs to be tailored to the needs of farmers and the specific pest problems they face. For example, the magnitude of mortality attributed to natural enemies may be less important than the timing and consistency of that mortality between seasons. Tailoring impact assessments will lead to research outcomes that do not simply provide general information about how to conserve natural enemies, but how to use these natural enemies as an integral part of decision-making.

关键词： mortality parasitism pest control predation semifield

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemokines,chemokine receptors and the gastrointestinal system

引用

world Journal of Gastroenterology 2013年第19期19卷 2847-2863页

作者： Hiroshi Miyazaki Kazuaki Takabe w andrew Yeudall Department of Biochemistry and Molecular Biology Virginia Commonwealth UniversityRichmondVA 23298United States philips Institute of Oral and Craniofacial Molecular Biology Virginia Commonwealth UniversityRichmondVA 23298United States Massey Cancer Center Virginia Commonwealth UniversityRichmondVA 23298United States Department of Biochemistry and Molecular Biology Virginia Commonwealth UniversityRichmondVA 23298United State Department of Surgery Virginia Commonwealth UniversityRichmondVA 23298United Statess

The biological properties of tumor cells are known to be regulated by a multitude of cytokines and growth factors,which include epidermal growth factor receptor agonists and members of the transforming growth factor β ***,the recent explosion of research in the field of chemokine function as mediators of tumor progression has led to the possibility that these small,immunomodulatory proteins also play key roles in carcinogenesis and may,therefore,be potential targets for novel therapeutic *** this review,we will summarize recently reported findings in chemokine biology with a focus on the gastrointestinal tract.

关键词： Chemokine Receptor Signal transduction Tumor progression Targeted therapeutics Digestive system Cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Regulation of antiviral innate immunity by deubiquitinase CYLD

引用

Cellular & Molecular Immunology 2011年第6期8卷 502-504页

作者： Minying Zhang andrew J lee Xuefeng wu Shao-Cong Sun Department of Immunology The University of Texas MD Anderson Cancer CenterHoustonTXUSA Department of Melanoma Medical Oncology The University of Texas MD Anderson Cancer CenterHoustonTXUSA Laboratory of Gene Regulation and Signal Transduction Department of PharmacologySchool of MedicineUniversity of California at San DiegoLa JollaCAUSA

An antiviral innate immune response involves induction of type I interferons(IFNs)and their subsequent autocrine and paracrine actions,but the underlying regulatory mechanisms are incompletely *** we report that CYLD,a deubiquitinase that specifically digests lysine 63-linked ubiquitin chains,is required for antiviral host *** of CYLD renders mice considerably more susceptible to infection by vesicular stomatitis virus(VSV).Consistently,CYLD-deficient dendritic cells are more sensitive to VSV *** functional defect was not due to lack of type I IFN production but rather because of attenuated IFN receptor *** the absence of CYLD,IFN-b is ineffective in the induction of antiviral genes and protection of cells from viral *** findings establish CYLD as a novel regulator of antiviral innate immunity and suggest a role for CYLD in regulating IFN receptor signaling.

关键词： antiviral innate immunity CYLD deubiquitinase interferon VSV

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular determinants for the layering and coarsening of biological condensates

Aggregate

引用

Aggregate 2022年第6期3卷 113-121页

作者： andrew p.Latham Bin Zhang Department of Chemistry Massachusetts Institute of TechnologyCambridgeMassachusettsUSA Department of Bioengineering and Therapeutic Sciences University of California at San FranciscoSan FranciscoCaliforniaUSA

Many membraneless organelles,or biological condensates,form through phase separation,and play key roles in signal sensing and transcriptional *** the functional importance of these condensates has inspired many studies to characterize their stability and spatial organization,the underlying principles that dictate these emergent properties are still being *** this review,we examine recent work on biological condensates,especially multicomponent *** focus on connecting molecular factors such as binding energy,valency,and stoichiometry with the interfacial tension,explaining the nontrivial interior organization in many *** further discuss mechanisms that arrest condensate coalescence by lowering the surface tension or introducing kinetic barriers to stabilize the multidroplet state.

关键词： biological condensate intrinsically disordered protein membraneless organelle phase separation surface tension

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluation of sampling strategies to estimate crown biomass

引用

Forest Ecosystems 2015年第1期2卷 20-30页

作者： Krishna p poudel Hailemariam Temesgen andrew N Gray Department of Forest Engineering Resources and Management College of Forestry Oregon State University USDA Forest Service PNW Research Station3200 SW Jefferson WayCorvallis OR 97331 USA

Background：Depending on tree and site characteristics crown biomass accounts for a significant portion of the total aboveground biomass in the *** biomass estimation is useful for different purposes including evaluating the economic feasibility of crown utilization for energy production or forest products,fuel load assessments and fire management strategies,and wildfire ***,crown biomass is difficult to predict because of the variability within and among species and *** the allometric equations used for predicting crown biomass should be based on data collected with precise and unbiased sampling *** this study,we evaluate the performance different sampling strategies to estimate crown biomass and to evaluate the effect of sample size in estimating crown ***：Using data collected from 20 destructively sampled trees,we evaluated 11 different sampling strategies using six evaluation statistics：bias,relative bias,root mean square error（RMSE）,relative RMSE,amount of biomass sampled,and relative biomass *** also evaluated the performance of the selected sampling strategies when different numbers of branches（3,6,9,and 12）are selected from each *** specific log linear model with branch diameter and branch length as covariates was used to obtain individual branch ***：Compared to all other methods stratified sampling with probability proportional to size estimation technique produced better results when three or six branches per tree were ***,the systematic sampling with ratio estimation technique was the best when at least nine branches per tree were *** the stratified sampling strategy,selecting unequal number of branches per stratum produced approximately similar results to simple random sampling,but it further decreased RMSE when information on branch diameter is used in the design and estimation ***：Use of auxiliary information in design or estimation phase reduc

关键词： Aboveground biomass Crown Sampling strategies pacific Northwest

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Flux Based Approximation to Simulate Coupled Hydromechanical problems for Mines with Heterogeneous Rock Types Using the Material point Method

引用

Computer Modeling in Engineering & Sciences 2022年第4期131卷 379-409页

作者： Gysbert Basson andrew p.Bassom Brian Salmon Institute of Mine Seismology and University of Tasmania Kingston7050Australia School of Natural Sciences-University of Tasmania Sandy BayHobart7001Australia School of Engineering-University of Tasmania Sandy BayHobart7001Australia

Advances in numerical simulation techniques play an important role in helpingmining engineers understand those parts of the rock mass that cannot be readily *** Material point Method(MpM)is an example of such a tool that is gaining popularity for studying geotechnical *** recent years,the original formulation of MpM has been extended to not only account for simulating the mechanical behaviour of rock under different loading conditions,but also to describe the coupled interaction of pore water and solid phases in *** methods assume that the permeability of mediums is homogeneous,and we show that these MpM techniques fail to accurately capture the correct behaviour of the fluid phase if the permeability of the material is *** this work,we propose a novel implementation of the coupled MpM to address this *** employ an approach commonly used in coupled Finite Volume Methods,known as the Two point Flux Approximation(TpFA).Our new method is benchmarked against two well-known analytical expressions(a one-dimensional geostatic consolidation and the so-called Mandel-Cryer effect).Its performance is compared to existing coupled MpM approaches for homogeneous *** order to gauge the possible effectiveness of our technique in the field,we apply ourmethod to a case study relating to a mine known to experience severe problems with pore water.

关键词： Fluid permeability Material point Method mining faults

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Recurrent hepatitis C after liver transplant

引用

world Journal of Gastroenterology 2014年第31期20卷 10668-10681页

作者： andrew S deLemos paul A Schmeltzer Mark w Russo Department of Medicine Center for Liver Diseases and Transplantation Carolinas Medical Center

End stage liver disease from hepatitis C is the most common indication for liver transplantation in many parts of the world accounting for up to 40% of liver transplants. Antiviral therapy either before or after liver transplantation is challenging due to side effects and lower efficacy in patients with cirrhosis and liver transplant recipients, as well as from drug interactions with immunosuppressants. Factors that may affect recurrent hepatitis C include donor age, immunosuppression, IL28 B genotype, cytomegalovirus infection, and metabolic syndrome. Older donor age has persistently been shown to have the greatest impact on recurrent hepatitis C. After liver transplantation, distinguishing recurrent hepatitis C from acute cellular rejection may be difficult, although the development of molecular markers may help in making the correct diagnosis. The advent of interferon free regimens with direct acting antiviral agents that include NS3/4A protease inhibitors, NS5 B polymerase inhibitors and NS5 A inhibitors holds great promise in improving outcomes for liver transplant candidates and recipients.

关键词： Hepatitis C Liver transplant Donor risk factors Immunosuppression protease inhibitors Fibrosing cholestatic hepatitis C Acute cellular rejection Cytomegalovirus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：