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Investigating the impact of dynamic structural changes of Au/rutile catalys.s.on the catalytic activity of CO oxidation

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Carbon Energy 2024年第4期6卷 222-232页

作者： Xiaochun Hu Qianwenhao Fan Mingwu Tan yuqing luo Xianyue wu Manoel y.Manuputty Jie ding Tej s.Choksi Markus Kraft Rong xu Zhiqiang sun wen liu school of Energy science and engineering Central South UniversityChangshaChina school of Chemistry Chemical Engineering and BiotechnologyNanyang Technological UniversitySingaporeSingapore Cambridge Centre for Advanced Research and Education SingaporeSingapore Institute of s.s.ainability for Chemicals Energy and EnvironmentJurong IslandSingapore College of Chemistry and Chemical engineering Central South UniversityChangshaChina department of Chemical engineering and Biotechnology University of CambridgeCambridgeUK

The surface properties of oxidic supports and their interaction with the supported metals play critical roles in governing the catalytic activities of oxide‐supported metal *** metals are supported on reducible oxides,dynamic surface reconstruction phenomena,including strong metal–support interaction(s.s.)and oxygen vacancy formation,complicate the determination of the structural–functional relationship at the active ***,we performed a s.s.ematic investigation of the dynamic behavior of Au nanocatalys.s.supported on flame‐synthesized TiO_(2),which takes predominantly a rutile phase,using CO oxidation above room temperature as a probe *** analys.s.conclusively elucidated a negative correlation between the catalytic activity of Au/TiO_(2) and the oxygen vacancy at the Au/TiO_(2) *** the reversible formation and retracting of s.s. overlayers have been ubiquitously observed on Au/TiO_(2) samples,the catalytic consequence of s.s. remains *** functional theory.s.gges.s.that the electron transfer from TiO_(2) to Au is correlated to the presence of the interfacial oxygen vacancies,retarding the catalytic activation of CO oxidation.

关键词： CO oxidation electronic metal-support interactions flame‐synthesis metal-support interactions oxygen vacancy strong metal-support interaction

sleep Promotion by 3-Hydroxy-4-Iminobutyric Acid in w.l.ut Diaphragma juglandis Fructus

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Research 2024年第2期6卷 613-627页

作者： Jian Ji yongli ye lina sheng Jiadi sun Qianqian Hong Chang liu Jun ding shuxiang Geng Deping xu yinzhi Zhang Xiulan sun state Key laboratory of Food science and Technology School of Food Science and TechnologyNational Engineering Research Center for Functional FoodSynergetic Innovation Center of Food Safety and Quality ControlJiangnan UniversityLihu Avenue 1800WuxiJiangsu 214100P.R.China College of Food science and Pharmacy Xinjang Agricultural UniversityNo.311 Nongda Dong RoadUrumqiXinjangUygur Autonomous Region 830052P.R.China department of Chemistry Wuhan UniversityWuhanHubei 430072P.R.China yunnan Academy of Forestry and Grassland KunmingYunnan 650201P.R.China

Insufficient sleep can produce a multitude of deleterious repercussions on various domains of human ***,the w.l.ut(Juglans mandshurica)confers numerous.s.lutary biological activities pertaining to ***,the sedative and hypnotic capacities of w.l.ut's functional constituents remain *** this investigation,we analyzed the sedative and hypnotic components of the w.l.ut Diaphragma juglandis fructus and innovatively discovered a compound,defined as 3-hydroxy-4-iminobutyric acid(HIBA),which disrupts motor activity and enhances.s.eep duration by regulating the neurotransmitters(GABA,DA,etc.)within the brain and serum of ***,a metabolomics approach of the serum,basal ganglia,hypothalamus,and hippocampus as w.l. as the gut microbiota was undertaken to unravel the underlying molecular mechanis.s.of sleep *** data reveal that HIBA can regulate the metabolism of basal ganglia(sphingolipids,acylcarnitines,etc.),possibly in relation to HIBA's influence on the gut microbiome(Muribaculum,Bacteroides,lactobacillus,etc.).Therefore,we introduce a novel natural product,HIBA,and explicate the modulation of sleep promotion in mice based on the microbiota-gut-brain *** study contributes fresh insights toward natural product-based sleep research.

关键词： metabolism promotion insight

sTCF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai l.P.An R.Aliberti Q.An X.Z.Bai y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.M.Cai H.Cai J.J.Cao Q.H.Cao X.Cao Z.Cao Q.Chang K.T.Chao D.y.Chen H.Chen H.X.Chen J.F.Chen K.Chen l.l.Chen P.Chen s.l.Chen s.M.Chen s.Chen s.P.Chen w.Chen X.Chen X.F.Chen X.R.Chen y.Chen y.Q.Chen H.y.Cheng J.Cheng s.Cheng T.G.Cheng J.P.Dai l.y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.ding l.y.Dong w.H.Dong V.Druzhinin D.s.Du y.J.Du Z.G.Du l.M.Duan D.Epifanov y.l.Fan s.s.Fang Z.J.Fang G.Fedotovich C.Q.Feng X.Feng y.T.Feng J.l.Fu J.Gao y.N.Gao P.s.Ge C.Q.Geng l.s.Geng A.Gilman l.Gong T.Gong B.Gou w.Gradl J.l.Gu A.Guevara l.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo y.P.Guo Z.H.Guo A.Guskov K.l.Han l.Han M.Han X.Q.Hao J.B.He s.Q.He X.G.He y.l.He Z.B.He Z.X.Heng B.l.Hou T.J.Hou y.R.Hou C.y.Hu H.M.Hu K.Hu R.J.Hu w.H.Hu X.H.Hu y.C.Hu J.Hua G.s.Huang J.s.Huang M.Huang Q.y.Huang w.Q.Huang X.T.Huang X.J.Huang y.B.Huang y.s.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia s.Jia Z.K.Jia H.B.Jiang J.Jiang s.Z.Jiang J.B.Jiao Z.Jiao H.J.Jing X.l.Kang X.s.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin y.lei E.levichev C.H.li C.li D.y.li F.li G.li G.li H.B.li H.li H.N.li H.J.li H.l.li J.M.li J.li l.li l.li l.y.li N.li P.R.li R.H.li s.li T.li w.J.li X.li X.H.li X.Q.li X.H.li y.li y.y.li Z.J.li H.liang J.H.liang y.T.liang G.R.liao l.Z.liao y.liao C.X.lin D.X.lin X.s.lin B.J.liu C.w.l.u D.liu F.liu G.M.liu H.B.liu J.liu J.J.liu J.B.liu K.liu K.y.liu K.liu l.liu Q.liu s.B.liu T.liu X.liu y.w.l.u y.liu y.l.liu Z.Q.liu Z.y.liu Z.w.l.u I.logashenko y.long C.G.lu J.X.lu N.lu Q.F.lü y.lu y.lu Z.lu P.lukin F.J.luo T.luo X.F.luo y.H.luo H.J.lyu X.R.lyu J.P.Ma P.Ma y.Ma y.M.Ma F.Maas.s.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev y.Nefedov s.l.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan y.Pan E.Passemar y.P.Pei H.P.Peng l.Peng X.y.Peng X.J.Peng K.Peters.s.Pivovarov E.Pyata B.B.Qi y.Q.Qi w.B.Qian y.Qian C.F.Qiao J.J.Qin J.J.Qin l.Q.Qin X.s.Qin T.l.Qiu J.Rademacker C.F.Redmer H.y.s.ng Anhui university Hefei 230039China Beihang university Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAs Key laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central china Normal university Wuhan 430079China Central south university Changsha 410083China china university of Geosciences Wuhan 430074China china university of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de lausanne(EPFl) LausanneSwitzerland Fudan university Shanghai 200433China Goethe university Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal university Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced study UCASHangzhou 310024China Hebei Normal university Shijiazhuang 050024China Hebei university Baoding 071002China Hefei university of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal university Xinxiang 453007China Henan university Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher school of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan university Huangshan 245000China Hubei university of Automotive Technology Shiyan 442002China Hunan Normal university Changsha 410081China Hunan university of science and Technology Xiangtan 411201China Hunan university Changsha 410082China Indiana university BloomingtonIndiana 47405USA Inner Mongolia university Hohhot 010021China Institute of Advanced science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin university Changch

The superτ-charm facility.s.CF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** sTCF w.l. produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as w.l. as.s.arching for exotic hadrons and physics beyond the standard *** sTCF project in china is under development with an extensive R&D *** document presents the physics opportunities at the sTCF,describes conceptual designs of the sTCF detector s.s.em,and discuss.s.future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity sTCF detector conceptual design

Mechanism analys.s.of foam penetration in EPB shield tunnelling with a focus on FER and soil particle size

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Underground space 2024年第4期17卷 170-187页

作者： He Huang Quan sun Tao xu wanhuan Zhou state Key laboratory of Internet of Things for smart City and department of Civil and Environmental engineering University of MacaoMacao 999078China department of Civil and Environmental engineering University of MacaoMacao 999078China school of Transportation Southeast UniversityNanjing 210000China

Parameters of foam penetration in earth pressure balance(EPB)shield tunnelling,such as permeability coefficients and penetration distances.s.gnificantly impact tunnel face ***,existing studies have faced inaccuracies in analysing these parameters due to imitations in experimental *** study address.s.this issue by employing enhanced methods for a more precise analys.s.of foam *** involving three distinct sand types(coarse,medium,and fine)and three foam expansion ratios(FER)(10,15,and 20)are conducted using a modified model test *** from a novel computer vision-based method,the model test outcomes unveil two distinct foam penetration paths:liquid migration(l_(w))and bubble migration(l_(f)).Three penetration phas.s.namely,injection,blockage&drainage,and breakage—are identified based on l_(w)and l_(f)*** initial"injection"phase conforms to Darcy.s.law and is amenable to mathematical *** foam with FER of 15 has the maximum viscosity and,hence the l_(f)and permeability in the penetration tes.s.with FER of 15 are the lowest in the same *** bubble size distribution of foam with different FER shows minor ***,the characteristics of foam penetration vary due to the distinct particle size distribution(PsD)of different *** penetration creates low-permeability layers in both medium and fine sands due to the larger bubble size of the foam compared to the estimated pore sizes of medium and fine *** the coarse sand results in a different situation due to its large pore *** distinctive characteristics of foam penetration in different sand strata are notably.s.aped by FER,PsD,and pore size *** insights.s.ed light on the complex interactions during foam penetration at the tunnel face,contributing valuable knowledge to EPB shield tunnelling practices.

关键词： EPB soil conditioning Foam penetration Permeability Tunnel face

High-efficiency Carbonation Modification Methods of Recycled Coarse Aggregates

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Journal of wuhan university of Technology(materials science) 2024年第2期39卷 386-398页

作者：张美香 yANG Xiaolin 丁亚红 sun Bo ZHANG Xianggang lÜXiuwen department of Civil engineering Henan Polytechnic UniversityJiaozuo 454150China College of Architectural engineering Xinyu UniversityXinyu 336500China

To solve the problem of only.s.rface carbonation and realize high-efficiency carbonation of recycled coarse aggregate,the method of carbonated recycled coarse aggregate with nano materials pre-soaking was first put *** carbonation effect of modified recycled coarse aggregate with three different carbonation methods was evaluated,and water absorption,apparent density and crush index of modified recycled coarse aggregate were *** with XRD,sEM,and MIP microscopic analys.s.the high-efficiency carbonation strengthening mechanism of modified recycled coarse aggregate was *** experimental results.s.ow that,compared with the non-carbonated recycled coarse aggregate,the physical and microscopic properties of carbonated recycled coarse aggregate are *** method of carbonation with nano-siO_(2) pre-soaking can realize the high-efficiency carbonation of recycled coarse aggregate,for modified recycled coarse aggregate with the method,water absorption is reduced by 23.03%,porosity is reduced by 44.06%,and the average pore diameter is 21.82 *** high-efficiency carbonation strengthening mechanism show that the pre-socked nano-siO_(2) is bound to the hydration product Ca(OH)_(2) of the old mortar with nano-scale C-s-H,which can improve the CO_(2) absorption rate,accelerate the carbonation reaction,generate more stable CaCO_(3) and nano-scale silica gel,and bond to the dense three-dimensional network structure to realize the bidirectional enhancement of nano-materials and pressurized *** is concluded that the method of carbonation with nano-siO_(2) pre-soaking is a novel high-efficiency carbonation modification of recycled coarse aggregate.

关键词： recycled coarse aggregate pressurized carbonation high-efficiency carbonation nano-siO2 strengthening mechanism

TRIM21-dependent ultrasmall chiral gold nanoparticles for preventing microglia senescence against Alzheimer's disease

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science china Chemistry 2024年第4期67卷 1360-1372页

作者： Meiru lu Changlong Hao liguang xu Feng yu Jiwei Jiang yanli wang Jun xu Hua Kuang Chuanlai xu Maozhong sun International Joint Research laboratory for Biointerface and Biodetection State Key Laboratory of Food Science and ResourcesSchool of Food Science and TechnologyJiangnan UniversityWuxi 214122China Institute of life sciences Jiangsu UniversityZhenjiang 212013China department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100050China National Clinical Research Center for Neurological Diseases Beijing 100070China

Tripartite motif 21(TRIM21)is an E3 ubiquitin ligase that shows great promise for protein degradation through ***,ultrasmall chiral gold nanoparticles(D-or l-NPs)modified by D-or l-glutathione ligands were *** conjugated with an NlR family pyrin domain-containing protein 3(NlRP3)antibody(D-NP-a NlRP3 or l-NP-a NlRP3),DNP-a NlRP3 showed effective delivery efficiency of the antibody into microglia and prevented Aβ-mediated microglia senescence,and p16^(ink4a),a marker of senescence,in the microglia was reduced by 90.3%±7.8% while l-NP-a NlRP3 decreased by 48.01%±3.1%.Mechanistic investigations revealed that the D-NP-a NlRP3((1.5±0.3)×10^(7)M^(-1))exhibited sixteen-fold larger binding affinity to transmembrane glycoprotein slC3A2 than l-type((9.5±2.7)×10^(5)M^(-1)),which led to a high efficiency of antibody delivery and TRIM21-dependent NlRP3 ***,the blood-brain barrier(BBB)-crossing ability of chiral NP-a NlRP3 as w.l. as NlRP3 degradation was demonstrated in *** APP/Ps1 Alzheimer's disease(AD)model mice experiments exhibited a reduction of 89.7%±6.8% for the NlRP3 protein and 84.2±7.5% for p16^(ink4a)following the intravenous administration of D-NP-a NlRP3 once a week for 60 ***,the levels of the AD markers Aβ and phosphorylatedTau in the brains were reduced by 86.2%±8.2% and 81.6%±9.1%;these were 2.1-fold and 1.9-fold higher than those treated with l-NP-a NlRP3,*** studies provide a method to rescue AD-like pathologies and prevent senescence.

关键词： chiral gold nanoparticles amyloid-β NlRP3 TRIM21 senescence Alzheimer's disease

Glucose metabolic reprogramming-related parameters for the prediction of 28-day neurological prognos.s.and all-cause mortality in patients after cardiac arrest:a prospective single-center observational study

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world Journal of Emergency Medicine 2024年第3期15卷 197-205页

作者： subi Abudurexiti shihai xu Zhangping sun yi Jiang Ping Gong department of Emergency Medicine Ruijin Hospital Affi liated to Shanghai Jiaotong University School of MedicineShanghai 200025China department of Emergency Medicine Shenzhen People's Hospital(the Second Clinical Medical CollegeJinan Universitythe First Affi liated HospitalSouthern University of Science and Technology)Shenzhen 518020China department of Emergency Medicine the First Affi liated Hospital of Dalian Medical UniversityDalian 116011China department of Emergency Medicine General Hospital of Tianjin Medical UniversityTianjin 300052China

BACKGROUND:we aimed to observe the dynamic changes in glucose metabolic reprogrammingrelated parameters and their ability to predict neurological prognos.s.and all-cause mortality in cardiac arrest patients after the restoration of spontaneous circulation(ROsC).METHODs:Adult cardiac arrest patients after ROsC who were admitted to the emergency or cardiac intensive care unit of the First Aflliated Hospital of Dalian Medical university from August 1,2017,to May 30,2021,were *** to 28-day.s.rvival,the patients were divided into a non-survival group(n=82) and a survival group(n=38).Healthy adult volunteers(n=40) of similar ages and sexes were selected as *** serum levels of glucose metabolic reprogrammingrelated parameters(lactate dehydrogenase [lDH],lactate and pyruvate),neuron-specific enolase(NsE) and interleukin 6(Il-6) were measured on days 1,3,and 7 after *** Acute Physiology and Chronic Health Evaluation II(APACHE II) score and sequential Organ Failure Ass.s.ment(sOFA) score were *** Cerebral Performance Category(CPC) score was recorded on day 28 after ***:Following ROsC,the serum lDH(607.0 U/l vs.286.5 U/l),lactate(5.0 mmol/l vs.2.0 mmol/l),pyruvate(178.0 μmol/l vs.70.9 μmol/l),and lactate/pyruvate ratio(34.1 vs.22.1) significantly increased and were higher in the non-survivors than in the survivors on admission(all Pserum lDH,pyruvate,Il-6,APACHE II score,and sOFA score on days 1,3 and 7 after ROsC were significantly associated with 28-day poor neurological prognos.s.and 28-day all-cause mortality(all Pserum lDH concentration on day 1 after ROsC had an area under the receiver operating characteristic curve(AUC) of 0.904 [95% confidence interval [95% CI]:0.851–0.957]) with 96.8% specificity for predicting 28-day neurological prognos.s.and an AUC of 0.950(95% CI:0.911–0.989) with 94.7% specificity for predicting 28-day all-cause mortality,which was the highest among the glucose metabo

关键词： Glucose metabolic reprogramming lactate dehydrogenase Cardiac arrest Prognosis

Effect of autologous bone marrow stem cells.s.affold transplantation on the ongoing pregnancy rate in intrauterine adhesion women:a randomized,controlled trial

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science china(life sciences) 2024年第1期67卷 113-121页

作者： Hui Zhu Taishun li Peizhen xu lijun ding Xianghong Zhu Bin wang Xiaoqiu Tang Juan li Pengfeng Zhu Huiyan wang Chenyan Dai Haixiang sun Jianwu Dai yali Hu department of Obstetrics and Gynecology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008China department of Biostatistics Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008China department of Gynecology Changzhou Maternal and Child Health Care HospitalChangzhou Medical CenterNanjing Medical UniversityChangzhou 213004China Clinical Center for stem Cell Research Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008China department of Hematology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008China Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100190China

Intrauterine adhesion is a major cause of female reproductive *** we and others uncontrolled pilot studies.s.owed that treatment with autologous bone marrow stem cells made a few patients with severe intrauterine adhesion obtain live birth,no large sample randomized controlled studies on this therapeutic strategy in such patients have been reported so *** verify if the therapy of autologous bone marrow stem cells.s.affold is.s.perior to traditional treatment in moderate to severe intrauterine adhesion patients in increasing their ongoing pregnancy rate,we conducted this randomized controlled clinical *** 195 participants with moderate to severe intrauterine adhesion were screened and 152 of them were randomly assigned in a 1:1 ratio to either group with autologous bone marrow stem cells.s.affold plus Foley balloon catheter or group with only Foley balloon catheter(control group)from February 2016 to January *** per-protocol analys.s.included 140 participants:72 in bone marrow stem cells.s.affold group and 68 in control *** ongoing pregnancy occurred in 45/72(62.5%)participants in the bone marrow stem cells.s.affold group which was.s.gnificantly higher than that in the control group(28/68,41.2%)(RR=1.52,95%CI 1.08–2.12,P=0.012).The situation was.s.milar in live birth rate(bone marrow stem cells.s.affold group 56.9%(41/72)*** group 38.2%(26/68),RR=1.49,95%CI 1.04–2.14,P=0.027).Compared with control group,participants in bone marrow stem cells.s.affold group showed more menstrual blood volume in the 3rd and 6th cycles and maximal endometrial thickness in the 6th cycle after hysteroscopic *** incidence of mild placenta accrete was increased in bone marrow stem cells.s.affold group and no severe adverse effects were *** conclusion,transplantation of bone marrow stem cells.s.affold into uterine cavities of the participants with moderate to severe intrauterine adhesion increased their ongoing pregnancy and

关键词： intrauterine adhesion Asherman’s.s.ndrome uterine infertility autologous bone marrow stem cells transplantation endometrial regeneration ongoing pregnancy rate

Tailored wrinkles for tunable sensing performance by.s.ereolithography

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Interdisciplinary materials 2024年第3期3卷 414-424页

作者： Ruiyi Jiang Jie Pu yuxuan wang Jipeng Chen Gangwen Fu xue Chen Jiayu yang Jianghua shen Xing sun Jun ding Xi xu Key laboratory of Flexible Electronics of Zhejiang Province Ningbo Institute of Northwestern Polytechnical UniversityNingboChina Frontiers science Center for Flexible Electronics Institute of Flexible ElectronicsNorthwestern Polytechnical UniversityXi'anChina Research&Development Institute of Northwestern Polytechnical University in ShenzhenNanshan DistrictShenzhenChina Affiliated Hospital of nanjing university of Chinese Medicine NanjingChina school of Aeronautics Northwestern Polytechnical UniversityXi'anChina Combustion Internal Flow and Thermal-Structure LaboratorySchool of AstronauticsNorthwestern Polytechnical UniversityXi'anChina department of materials science and engineering Faculty of EngineeringNational University of SingaporeSingapore

Conducting polymer hydrogel can address the challenges of stricken biocompatibility and ***,conventional conducting polymer hydrogels are often brittle and weak due to the intrinsic quality of the material,which exhibits *** property may cause a delay in sensor response time due to *** overcome these limitations,we have designed a wrinkle morphology three-dimensional(3D)substrate using digital light processing technology and then followed by in situ polymerization to form interpenetrating polymer network *** novel design results in a wrinkle morphology conducting polymer hydrogel elastomer with high precision and geometric freedom,as the size of the wrinkles can be controlled by adjusting the treating *** wrinkle morphology on the conducting polymer hydrogel effectively reduces its viscoelasticity,leading to samples with quick response time,low hysteres.s.stable cyclic performance,and remarkable res.s.ance ***,the 3D gradient structure augmented the sensor's.s.nsitivity under minimal stress while exhibiting cons.s.ent sensing *** properties indicate the potential of the conducting polymer hydrogel as a flexible sensor.

关键词： 3D printing conducting polymer hydrogel flexible sensor micro-wrinkle structure