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Journal of Materials Science & Technology 2022年第7期102卷 213-223页

作者： Z.w.wang J.f.Zhang G.M.Xie L.H.wu H.Zhang P.Xue D.R.Ni B.L.Xiao Z.Y.Ma Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang110819China

Ultrahigh-strength quenching and partitioning(Q&P) steels have attracted strong interests in the auto manufactory,while the comprehensive understanding in the microstructure and mechanical behavior of their welded joints is highly needed to enrich their *** the present work,it is designed to make an insight into these imperative *** strength Q&P 1180 steel joints to parent metal were successfully fabricated via friction stir welding(fSw) technique under different parameters. Apparent hardening and softening were observed in stir zone(SZ) and heat-affected zone(HAZ) respectively,whose microstructures strongly depended on the peak temperature and cooling rate during *** formation of fresh martensite was the main mechanism for the SZ hardening,while the decomposition of metastable phases played key roles in the microhardness drop of the HAZ.A heat source zone-isothermal phase transition layer model was proposed to clarify the impregnability of the joint strength under parameter *** dual-phase structure,nano-carbide particles,tempered initial martensite,and ultrafine-grained ferrite synergistically improved the strain hardening ability of the HAZ,which eventually resulted in the equal strength fSw joints.

关键词： Ultrahigh-strength Q&P steel friction stir welding Microstructure Mechanical property Strain hardening

Investigation of Chemical Properties by NMR During the Laboratory Aging of Asphalt

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武汉理工大学学报 2010年第17期32卷 43-46页

作者： MA L X wu S P HUANG J f School of Transportation Wuhan University of TechnologyWuhan 430063China Key Laboratory of Silicate Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China Communications Planning and Design Institute of Hubei Province Wuhan 430051China

In this work,the chemical properties of asphalt were evaluated during the laboratory aging. The rolling thin film oven (RTfO),termed as short-term aging,and pressurized aging vessel (PAV),termed as long-term aging. Tests were used to simulate the laboratory aging of this asphalt. The performance characteristics of asphalt depends the chemical composition of asphalt. NMR spectroscopy enables etailed information about the Carbon-and-hydrogen types of asphalt without separating it into different components. Carbon and proton NMR measurements of asphalt showed that isomerization was the main chemical reactions of hydrocarbon groups following aging. The Corbett fractionation procedure was used to separate fresh and aged asphalts into four generic fractions,namely; asphaltenes,aromatics,resins and saturates were applied to evaluate the chemical changes that occurred during the aging processes.

关键词： asphalt ageing chemical characteristics NMR

Nanotechnology for water Treatment: Is It the Best Solution Now?

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Journal of Earth Science 2023年第5期34卷 1616-1620页

作者： Moustafa Gamal Snousy Hassan Mohamed Helmy Jianhua wu M.f.Zawrah A.Abouelmagd Egyptian Petroleum Sector Petrotrade Co.1 Anwar Al Moftty St.-Abbas El Akkad St.-Nasr CityCairoEgypt Geology Department Faculty of ScienceMinia UniversityEl-Minia 61519Egypt School of water and Environment Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Key Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region of the Ministry of Education Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Key Laboratory of Eco-Hydrology and water Security in Arid and Semi-Arid Regions of the Ministry of water Resources Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Refractory Ceramics and Building Materials DepartmentCenter of Excellence for Advanced SciencesAdvanced Materials and Nano GroupNational Research CentreCairo 12622-DokkiEgypt Egyptian Petroleum Sector 85 Nasr Road1st DistrictNasr CityCairoEgypt

INTRODUCTION Preservation of the freshwater resources is a big challenge for a healthy civilized *** water consumption increased more than twice the population increase rate,drinking water pollution and freshwater shortage increased dramatically during the last decades(Kar et al.,2012;Mueller and Nowack,2010).Only 0.01%of freshwater resources are suitable for human needs(Rashid et al.,2019),even in the areas of abundant freshwater(Yeston et al.,2006).By 2050,over 5 billion of the world population will be under severe fresh water supply conditions due to climate change and urbanization exacerbate(Sealy,2019;Oves et al.,2015;Kar et al.,2012).Currently,one billion people drink unhygienic water,especially in developing countries which leads to severe waterborne diseases which might cause death(Aminiyan et al.,2018).Twelve million people die every year due to this problem(Zhao et al.,2019;Oves et al.,2015).

关键词： abundant freshwater pollution

A multipath resource updating approach for distributed controllers in software-defined network.

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Science China(Information Sciences) 2016年第9期59卷 227-236页

作者： Xiaochun wu Chunming wu Changting LIN Qiang wu Bin wANG Computer Science College Zhejiang University Institute of Network and Communication Engineering Zhejiang Gongshang University ZTE Central R&D ZTE Corporation

finding effective ways to collect the usage of network resources in all kinds of applications to ensure a distributed control plane has become a key requirement to improve the controller’s decision making *** paper explores an efficient way in combining dynamic Net View sharing of distributed controllers with the behavior of intra-service resource announcements and processing requirements that occur in distributed controllers, and proposes a rapid multipathing distribution mechanism. firstly, we establish a resource collecting model and prove that the prisoner’s dilemma problem exists in the distributed resource collecting process in the Software-defined Network(SDN). Secondly, we present a bypass path selection algorithm and a diffluence algorithm based on Q-learning to settle the above dilemma. At last, simulation results are given to prove that the proposed approach is competent to improve the resource collecting efficiency by the mechanism of self-adaptive path transmission ratio of our approach, which can ensure high utilization of the total network we set up.

关键词： multipath Pareto optimal Q-learning

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基于DSC控制的数字功率因数校正模块应用

电工技术学报 2006年第12期21卷 98-103,121页

作者：陈新 Charlie wu w.Hutchings 南京航空航天大学航空电源航空科技重点实验室南京210016 freescale Semiconductor Inc. arizona85284

数字控制技术和电力电子应用之间结合逐渐紧密,功率因数校正(PfC)是电力电子技术的一个重要应用,本文利用freescale公司新数字信号控制器(DSC)MC56f8323,完成了基于DSC的功率因数校正模块应用研究。本文提供了PfC变换器的完整数字控制... 详细信息

数字控制技术和电力电子应用之间结合逐渐紧密,功率因数校正(PfC)是电力电子技术的一个重要应用,本文利用freescale公司新数字信号控制器(DSC)MC56f8323,完成了基于DSC的功率因数校正模块应用研究。本文提供了PfC变换器的完整数字控制解决方案,包括改进的数字PfC算法设计、适用于数字控制特点的变换器模型分析和控制参数推导、基于DSC的PfC变换器的系统软件设计、以及PwM控制信号产生策略等,最后用一台500w实验样机验证了数字控制的优良系统性能。

关键词：功率因数校正数字信号控制器 PI控制数字控制

In vitro Study on Biodegradable AZ31 Magnesium Alloy fibers Reinforced PLGA Composite

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Journal of Materials Science & Technology 2013年第6期29卷 545-550页

作者： Y.H.wu N.Li Y.Cheng Y.f.Zheng Y.Han Center for Biomedical Materials and Tissue Engineering Academy for Advanced Interdisciplinary StudiesPeking University Department of Materials Science and Engineering College of EngineeringPeking University State Key Laboratory for Mechanical Behavior of Materials Xi'an Jiaotong University

AZ31 magnesium alloy fibers reinforced poly（lactic-co-glycolic acid）（PLGA） composites were prepared and their mechanical property, immersion corrosion behavior and biocompatibility were studied. The tensile test showed that with the addition of AZ31 fibers, the composites had a significant increment in tensile strength and elongation. for the direct cell attachment test, all the cells showed a healthy morphology and spread well on the experimental sample surfaces. The immersion results indicated that pH values of the immersion medium increased with increasing AZ31 fiber contents. All the in vitro experimental results indicated that this new kind of magnesium alloy fibers reinforced PLGA composites show a potential for future biomedical applications.

关键词： Biomaterials Corrosion Polymeric composites AZ31 magnesium fiber

Carbon nanodots:A metal-free,easy-to-synthesize,and benign emitter for light-emitting electrochemical cells

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Nano Research 2022年第6期15卷 5610-5618页

作者： Yongfeng Liu Shi Tang Xiuyu wu Nicolas Boulanger Eduardo Gracia-Espino Thomas wågberg Ludvig Edman Jia wang Department of Physics UmeåUniversitySE-90187 UmeåSweden LunaLEC AB Linnaeus väg 24SE-90187 UmeåSweden College of Physical Science and Technology Yangzhou UniversityYangzhou 225009China

Light-emitting electrochemical cells(LECs)can be fabricated with cost-efficient printing and coating methods,but a current drawback is that the LEC emitter is commonly either a rare-metal complex or an expensive-to-synthesize conjugated ***,we address this issue through the pioneering employment of metal-free and facile-to-synthesize carbon nanodots(CNDs)as the emitter in functional LEC ***-shaped(average diameter=4.4 nm)and hydrophilic CNDs,which exhibit narrow cyan photoluminescence(peak=485 nm,full width at half maximum=30 nm)with a high quantum yield of 77%in dilute ethanol solution,were synthesized with a catalyst-free,one-step solvothermal process using low-cost and benign phloroglucinol as the sole starting *** propensity of the planar CNDs to form emission-quenching aggregates in the solid state was inhibited by the inclusion of a compatible 2,7-bis(diphenylphosphoryl)-9,9’-spirobifluorene host compound,and we demonstrate that such pristine host-guest CND-LECs turn on to a peak luminance of 118 cd·m^(−2)within 5 s during constant current-density driving at 77 mA·cm^(−2).

关键词： carbon nanodot light-emitting electrochemical cell phloroglucinol sustainable synthesis solution-based fabrication

CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer

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Cancer Communications 2021年第2期41卷 121-139页

作者： Ailin Chen Shijun wen fang Liu Zijian Zhang Meiling Liu Yuanzhong wu Bin He Min Yan Tiebang Kang Eric w.f.Lam Zifeng wang Quentin Liu Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdong 510060P.R.China Institute of Cancer Stem Cell Dalian Medical UniversityDalianLiaoning 116044P.R.China Department of Surgery and Cancer Imperial College LondonW120NNLondonUK

Background:Overexpression of Aurora-A(AURKA)is a feature of breast cancer and associates with adverse *** selective Aurora-A inhibitor alisertib(MLN8237)has recently demonstrated promising antitumor responses as a single agent in various cancer types but its phase III clinical trial was reported as a failure since MLN8237 did not show an apparent effect in prolonging the survival of ***,identification of potential targets that could enhance the activity of MLN8237 would provide a rationale for drug combination to achieve better therapeutic ***:Here,we conducted a systematic synthetic lethality CRISPR/Cas9 screening of 507 kinases using MLN8237 in breast cancer cells and identified a number of targetable kinases that displayed synthetic lethality interactions with ***,we performed competitive growth assays,colony formation assays,cell viability assays,apoptosis assays,and xenograft murine model to evaluate the synergistic therapeutic effects of Haspin(GSG2)depletion or inhibition with *** mechanistic studies,immunofluorescence was used to detect the state of microtubules and the localization of Aurora-B and mitotic centromere-associated kinesin(MCAK).Results:Among the hits,we observed that Haspin depletion or inhibition marginally inhibited breast cancer cell growth but could substantially enhance the killing effects of *** studies showed that co-treatment with Aurora-A and Haspin inhibitors abolished the recruitment of Aurora-B and mitotic centromere-associated kinesin(MCAK)to centromeres which were associated with excessive microtubule depolymerization,kinetochore-microtubule(KT-MT)attachment failure,and severe mitotic *** further showed that the combination of MLN8237 and the Haspin inhibitor CHR-6494 synergistically reduced breast cancer cell viability and significantly inhibited both in vitro and in vivo tumor ***:These findings establish Haspin as a synthetic lethal targe

关键词： alisertib Aurora-A breast cancer CHR-6494 CRISPR/Cas9 screening haspin kinetochoremicrotubule mitotic centromere-associated kinesin synthetic lethal xenograft

Artificial intelligence in medical imaging of the liver

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world Journal of Gastroenterology 2019年第6期25卷 672-682页

作者： Li-Qiang Zhou Jia-Yu wang Song-Yuan Yu Ge-Ge wu Qi wei You-Bin Deng Xing-Long wu Xin-wu Cui Christoph f Dietrich Sino-German Tongji-Caritas Research Center of Ultrasound in Medicine Department of Medical Ultrasound Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Department of Ultrasound Tianyou Hospital Affiliated to Wuhan University of Technology School of Mathematics and Computer Science Wuhan Textitle University Medical Clinic 2 Caritas-Krankenhaus Bad Mergentheim Academic Teaching Hospital of the University of Würzburg

Artificial intelligence(AI), particularly deep learning algorithms, is gaining extensive attention for its excellent performance in image-recognition tasks. They can automatically make a quantitative assessment of complex medical image characteristics and achieve an increased accuracy for diagnosis with higher efficiency. AI is widely used and getting increasingly popular in the medical imaging of the liver, including radiology, ultrasound, and nuclear medicine. AI can assist physicians to make more accurate and reproductive imaging diagnosis and also reduce the physicians' workload. This article illustrates basic technical knowledge about AI, including traditional machine learning and deep learning algorithms, especially convolutional neural networks, and their clinical application in the medical imaging of liver diseases, such as detecting and evaluating focal liver lesions, facilitating treatment, and predicting liver treatment response. we conclude that machine-assisted medical services will be a promising solution for future liver medical care. Lastly, we discuss the challenges and future directions of clinical application of deep learning techniques.

关键词： Liver Imaging Ultrasound Artificial intelligence Machine learning Deep learning

CO oxidation over ceria supported Au_(22) nanoclusters: Shape effect of the support

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Chinese Chemical Letters 2018年第6期29卷 795-799页

作者： Zili wu David R.Mullins Lawrence f.Allard Qianfan Zhang Laisheng wang Chemical Science Division and Center for Nanophase Materials Sciences Oak Ridge National Laboratory Materials Science and Technology Division Oak Ridge National Laboratory Department of Chemistry Brown University

Gold（Au） nanoclusters have recently emerged as ideal models for understanding Au catalysis, because the nanosized Au particles have precise atomic numbers and uniform size. In this work, we studied for the first time the support shape effect on the catalysis of Au nanoclusters by using CO oxidation as a model reaction. Au22（L8）6（L = 1,8-bis（diphenylphosphino） octane） nanoclusters were supported on CeO2 rods or cubes, then pretreated at different temperatures（up to 673 K）, allowing the gradual removal of the organic phosphine ligands. CO oxidation test over these differently pretreated samples shows that CeO2 rods are much better supports than cubes for Au22 nanoclusters in enhancing the reaction rate. In situ IR spectroscopy coupled with CO adsorption indicates that the shape of CeO2 support can impact the nature and quantity of exposed Au sites, as well as the efficiency of organic ligand removal. Although CeO2 rods are helpful in exposing a greater percentage of total Au sites upon ligands removal, the percentage of active Au sites（denoted by Au d＋, 0 〈 d 〈 1） is lower than that on CeO2 cubes. The in situ extended X-ray absorption spectroscopy（EXAfS） and high-angle annular dark-field scanning transmission electron microscopy（HAADf-STEM） results show that the Au nanoclusters bound more strongly to the CeO2 rods than to the cubes where the Au nanoclusters show more sintering. Considering the typical redox mechanism for CO oxidation over supported Au nanoclusters and nanoparticles, it is concluded that the reactivity of the lattice oxygen of CeO2 is the determining factor for CO oxidation over Au22/CeO2. CeO2 rods offer more reactive lattice oxygen and abundant oxygen vacancies than the cubes and thus make the rods a superior support for Au nanoclusters in catalyzing low temperature CO oxidation.

关键词： Gold nanoclusters Ceria Ligands Support shape CO oxidation