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骨关节炎的膝关节软骨损伤:ACRIN-PA 4001多中心试验研究分析MRI生物标记物的可重复性

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国际医学放射学杂志 2011年第3期 279-279页

作者： T.J.Mosher R.Reddy S.boudhar b.N.Milestone w.b.morrison 赵芳 Department of Radiology Penn State University College of Medicine Penn State University Hospital 500 University DrHersheyPA 17033

目的多中心试验对骨关节炎(OA)病人及无症状对照者进行研究,前瞻性确定膝关节软骨形态学及构成(T1ρ纵向弛豫时间,T2)的MRI生物标记物的可重复性。材料与方法本研究符合HIPAA要求,经参与方伦理审查委员会

关键词：骨关节炎膝关节软骨可重复性 ACRIN-PA 4001 标记物 MRI

脊椎节段变异对腰椎MR成像中椎体编号的影响

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国际医学放射学杂志 2011年第3期 288-288页

作者： J.A.Carrino P.D.Campbell w.b.morrison M.E.Schweitzer A.E.Flanders 李宁 Russell H.Morgan Department of Radiology and Radiological Sciences Johns Hopkins University School of Medicine

目的确认髂腰韧带(ILL)的位置,评估腰骶段移行椎(TV)(LSTV)的MR成像的形态学特征,并确定移行情况是否与异常的椎体排序相关。材料与方法该回顾性研究符

关键词： MR 椎体腰椎

联合超声和MR用于棒球运动员外侧肘关节疼痛方面关节成像技术的潜在应用

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国际医学放射学杂志 2016年第4期 440-440页

作者： J.b.Roedl F.M.Gonzalez A.C.Zoga w.b.morrison M.T.Nevalainen M.G.Ciccotti 饶良俊 Department of Radiology Thomas Jefferson University Hospital Jefferson Medical College

摘要目的评估超声(传统超声、外翻应力超声)和MR关节成像联合应用于棒球球员外侧肘部疼痛的价值。材料与方法本研究经过伦理委员会同意,入组病人已签署知情同意书。本研究符合HIPAA。对外侧肘部疼痛的棒球球员们分别行超声和MRI检查,并... 详细信息

摘要目的评估超声(传统超声、外翻应力超声)和MR关节成像联合应用于棒球球员外侧肘部疼痛的价值。材料与方法本研究经过伦理委员会同意,入组病人已签署知情同意书。本研究符合HIPAA。对外侧肘部疼痛的棒球球员们分别行超声和MRI检查,并评估不同形态的影像征象,然后全

关键词：超声检查侧副韧带敏感度肘关节疼痛棒球运动员特异度 MR 关节运动器官

Intrumer:A Multi Module Distributed Explainable IDS/IPS for Securing Cloud Environment

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Computers, Materials & Continua 2025年第1期82卷 579-607页

作者： Nazreen banu A S.K.b.Sangeetha Department of Computer Science and Engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increasing use of cloud-based devices has reached the critical point of cybersecurity and unwanted network *** environments pose significant challenges in maintaining privacy and *** approaches,such as IDS,have been developed to tackle these ***,most conventional Intrusion Detection System(IDS)models struggle with unseen cyberattacks and complex high-dimensional *** fact,this paper introduces the idea of a novel distributed explainable and heterogeneous transformer-based intrusion detection system,named INTRUMER,which offers balanced accuracy,reliability,and security in cloud settings bymultiplemodulesworking together within *** traffic captured from cloud devices is first passed to the TC&TM module in which the Falcon Optimization Algorithm optimizes the feature selection process,and Naie bayes algorithm performs the classification of *** selected features are classified further and are forwarded to the Heterogeneous Attention Transformer(HAT)*** this module,the contextual interactions of the network traffic are taken into account to classify them as normal or malicious *** classified results are further analyzed by the Explainable Prevention Module(XPM)to ensure trustworthiness by providing interpretable *** the explanations fromthe classifier,emergency alarms are transmitted to nearby IDSmodules,servers,and underlying cloud devices for the enhancement of preventive *** experiments on benchmark IDS datasets CICIDS 2017,Honeypots,and NSL-KDD were conducted to demonstrate the efficiency of the INTRUMER model in detecting network trafficwith high accuracy for different *** outperforms state-of-the-art approaches,obtaining better performance metrics:98.7%accuracy,97.5%precision,96.3%recall,and 97.8%*** results validate the robustness and effectiveness of INTRUMER in securing diverse cloud environments against sophisticated cyber threats.

关键词： Cloud computing intrusion detection system transformers and explainable artificial intelligence(XAI)

Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

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Federated Learning’s Role in Next-Gen TV Ad Optimization

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Computers, Materials & Continua 2025年第1期82卷 675-712页

作者： Gabriela Dobrita Simona-Vasilica Oprea Adela bâra Department of Economic Informatics and Cybernetics Bucharest University of Economic StudiesBucharest010374Romania

In the rapidly evolving landscape of television advertising,optimizing ad schedules to maximize viewer engagement and revenue has become *** methods often operate in silos,limiting the potential insights gained from broader data analysis due to concerns over privacy and data *** article introduces a novel approach that leverages Federated Learning(FL)to enhance TV ad schedule optimization,combining the strengths of local optimization techniques with the power of global Machine Learning(ML)models to uncover actionable insights without compromising data *** combines linear programming for initial ads scheduling optimization with ML—specifically,a K-Nearest Neighbors(KNN)model—for predicting ad spot *** into account the diversity and the difficulty of the ad-scheduling problem,we propose a prescriptivepredictive approach in which first the position of the ads is optimized(using Google’s OR-Tools CP-SAT)and then the scheduled position of all ads will be the result of the optimization ***,this output becomes the target of a predictive task that predicts the position of new entries based on their characteristics ensuring the implementation of the scheduling at large scale(using KNN,Light Gradient boosting Machine and Random Forest).Furthermore,we explore the integration of FL to enhance predictive accuracy and strategic insight across different broadcasting networks while preserving data *** FL approach resulted in 8750 ads being precisely matched to their optimal category placements,showcasing an alignment with the intended diversity ***,there was a minimal deviation observed,with 1133 ads positioned within a one-category variance from their ideal placement in the original dataset.

关键词： Ad scheduling prescriptive-predictive approach federated learning KNN

Spatially biased dispersal of acorns by a scatter-hoarding corvid may accelerate passive restoration of oak habitat on California＇s largest island

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Current Zoology 2017年第4期63卷 363-367页

作者： Mario b. PESENDORFER T. Scott SILLETT Scott A. morrison School of biological Sciences University of Nebraska - Lincoln 348 Manter Hall Lincoln NE 68588-0118 USA Migratory bird Center Smithsonian Conservation Biology Institute National Zoological Park MRC 5503 Washington D.C. 20013-7012 USA Cornell Lab of Ornithology 159 Sapsucker Woods Rd Ithaca NY 14850 USA The Nature Conservancy 4th Floor 201 Mission Street San Francisco CA 94105 USA

Scatter hoarding by corvids （crows, jays, magpies, and nutcrackers） provides seed dispersal for many large-seeded plants, including oaks and pines. when hoarding seeds, corvids often choose nonrandom locations throughout the landscape, resulting in differential survival of seeds. In the context of habitat restoration, such disproportional storing of seeds in areas suitable for germin- ation and establishment can accelerate expansion and recovery of large-seeded tree populations and their associated ecosystems. Here, we investigate the spatial preferences of island scrub jays Aphelocoma insularis during scatter hoarding of acorns （Quercus spp.） on Santa Cruz Island. we use a large behavioral data set on the birds＇ behavior in combination with seedling surveys and spatial analysis to determine whether 1） island scrub jays disproportionally cache seeds in specific habitat types, and 2） whether the preferred habitat type is suitable for oak regeneration. Our results show that the jays nonrandomly cache acorns across the landscape; they use chaparral and coastal sage scrub disproportionally while avoiding open and grassy areas. The areas used most often for caching were also the areas with the highest oak seedling densities. we discuss the potential role of these findings for the recovery of Santa Cruz Island＇s oak habitat since the 1980s.

关键词： Aphelocoma insularis directional dispersal habitat restoration Quercus spp. scatter hoarding seed dispersal.

Disruption of Cortical Microtubules by Overexpression of Green Fluorescent Protein-Tagged a-Tubulin 6 Causes a Marked Reduction in Cell wall Synthesis

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Journal of Integrative Plant biology 2006年第1期48卷 85-98页

作者： David H. burk Ruiqin Zhong w. Herbert morrison III Zheng-Hua Ye Department of Plant biology University of Georgia Athens Georgia 30602 USA Richard b. Russell Agriculture Research Center U.S. Department of Agriculture Agricultural Research Service Athens Georgia 30604 USA

It has been known that the transverse orientation of cortical microtubules （MTs） along the elongation axis is essential for normal cell morphogenesis, but whether cortical MTs are essential for normal cell wall synthesis is still not clear. In the present study, we have investigated whether cortical MTs affect cell wall synthesis by direct alteration of the cortical MT organization in Arabidopsis thaliana. Disruption of the cortical MT organization by expression of an excess amount of green fluorescent protein-tagged a-tubulin 6 （GFP-TUA6） in transgenic Arabidopsis plants was found to cause a marked reduction in cell wall thickness and a de- crease in the cell wall sugars glucose and xylose. Concomitantly, the stem strength of the GFP-TUA6 overexpressors was markedly reduced compared with the wild type. In addition, expression of excess GFP- TUA6 results in an alteration in cell morphogenesis and a severe effect on plant growth and development. Together, these results suggest that the proper organization of cortical MTs is essential for the normal synthesis of plant cell walls.

关键词： Arabidopsis thaliana cell elongation cell wall synthesis cortical microtubules microtubule organization.