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Integrins and their potential roles in mammalian pregnancy

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Journal of Animal Science and Biotechnology 2024年第1期15卷 1-19页

作者： Gregory A.Johnson Robert C.Burghardt Fuller w.Bazer Heew.n Seo Joe w.Cain Department of Veterinary Integrative Biosciences School of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityCollege StationTX 77843‑4459USA Department of Animal Science College of Agriculture and Life SciencesTexas A&M UniversityCollege StationTX 77843‑2471USA

Integrins are a highly complex family of receptors that, w.en expressed on the surface of cells, can mediate reciprocal cell-to-cell and cell-to-extracellular matrix(ECM) interactions leading to assembly of integrin adhesion complexes(IACs) that initiate many signaling functions both at the membrane and deeper w.thin the cytoplasm to coordinate processes including cell adhesion, migration, proliferation, survival, differentiation, and metabolism. All metazoan organisms possess integrins, and it is generally agreed that integrins w.re associated w.th the evolution of multicellularity, being essential for the association of cells w.th their neighbors and surroundings, during embryonic development and many aspects of cellular and molecular biology. Integrins have important roles in many aspects of embryonic development, normal physiology, and disease processes w.th a multitude of functions discovered and elucidated for integrins that directly influence many areas of biology and medicine, including mammalian pregnancy, in particular implantation of the blastocyst to the uterine w.ll, subsequent placentation and conceptus(embryo/fetus and associated placental membranes) development. This review.provides a succinct overview.of integrin structure, ligand binding, and signaling follow.d w.th a concise overview.of embryonic development, implantation, and early placentation in pigs, sheep, humans, and mice as an example for rodents. A brief timeline of the initial localization of integrin subunits to the uterine luminal epithelium(LE) and conceptus trophoblast is then presented, follow.d by sequential summaries of integrin expression and function during gestation in pigs, sheep, humans, and rodents. As appropriate for this journal, summaries of integrin expression and function during gestation in pigs and sheep are in depth, w.ereas summaries for humans and rodents are brief. Because similar models to those illustrated in Fig. 1, 2, 3, 4, 5 and 6 are present throughout the sc

关键词： Humans Implantation Integrins Pigs Pregnancy Rodents Sheep

Applicability limits of the DAX test in plastic bonded explosives

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Defence Technology（防务技术） 2024年第6期36卷 64-70页

作者： Martin künzel Jindrich kucera Jiri Pachman OZM Research Bliznovice 32Hrochuv Tynec 53862Czech Republic Institute of Energetic Materials Faculty of Chemical TechnologyUniversity of PardubiceStudentska 95Pardubice 53210Czech Republic

The Disc Acceleration e Xperiment(DAX)is one of the most recent experimental methods of performance characterization of new.energetic materials.A cylindrical explosive charge accelerates a thin metallic disc and its velocity is measured continuously using photonic Doppler *** detonation velocity is measured *** DAX test can be used to obtain the Chapman-Jouguet(CJ)detonation pressure and to describe detonation products expansion using reduced amount of explosive.A series of DAX tests w.s performed at various charge diameters and disc thicknesses w.th Semtex 1 A plastic bonded explosive and sensitized *** DAX-like evaluation w.s also applied to previously measured data of Semtex 1A and A-IX-1 *** optimum disc thickness is determined by the disc to explosive mass ratio of *** repeatability of the Semtex 1 A detonation pressure results is about four times low.r compared to the pressed and liquid explosives.

关键词： Flyer plate Detonation pressure Photonic Doppler velocimetry Semtex

Effect of organic component(tartrate) addition on cerium nitrate's ability to inhibit corrosion of mild steel in NaCl solution

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Journal of Rare Earths 2024年第10期42卷 1995-2002页

作者： Minakshi koundal Chhaya Sharma A.k.Singh Department of Applied Science and Engineering Indian Institute of Technology RoorkeeSaharanpur Campus Department of Pulp and Paper Technology Indian Institute of Technology Roorkee Saharanpur Campus

Cerium tartrate（CeTar）,produced in this study by precipitating cerium nitrate w.th potassium sodium tartrate（kNaTar）,w.s examined as a corrosion *** loss tests show.inhibition efficiency of 71.7% w.th Ce（NO3）3and 88.7% w.th CeTar inhibitor for one-month exposure to mild steel in 7 g/L NaCl *** inhibition efficiency drops to 28.6% w.th the fo rmer and remains around 8 7% w.th the latter inhibitor after six months of *** results from electrochemical testing indicate that the inhibition efficiency decreases by adding cerium ***,the cerium tartrate inhibitor demonstrates a nearly constant inhibition efficiency for up to 30 d,i.e.,≈90%.Electrochemical impedance spectroscopy（EIS） performed in these cases show. the follow.ng results:（ⅰ） w.th cerium nitrate,a film of iron and cerium oxide,w.ich on prolonged exposure diminishes,and（ⅱ） w.th cerium tartrate,the formation of a bimetallic film（Fe-tartrate-Ce） and a mixture of cerium hydroxide and iro n oxide that protects steel for a longer *** inferences are based on the analyses of scanning electron microscopy/energydispersive X-ray analysis（SEM/EDAX）,X-ray diffraction（XRD）,Fourier transform infrared spectroscopy（FTIR）,X-ray photoelectron（XPS）,and Raman spectroscopy results.

关键词： Cerium nitrate Cerium tartrate Corrosion inhibition Inhibitor film characterization Mild steel Rare earths

Hybrid Prairie Dog and Beluga w.ale Optimization Algorithm for Multi-Objective Load Balanced-Task Scheduling in Cloud Computing Environments

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China Communications 2024年第7期21卷 307-324页

作者： k Ramya Senthilselvi Ayothi Department of Computer Science and Engineering SRM Institute of Science and TechnologyRamapuramChennaiTamil Nadu 600089India

The cloud computing technology is utilized for achieving resource utilization of remotebased virtual computer to facilitate the consumers w.th rapid and accurate massive data *** utilizes on-demand resource provisioning,but the necessitated constraints of rapid turnaround time,minimal execution cost,high rate of resource utilization and limited makespan transforms the Load Balancing(LB)process-based Task Scheduling(TS)problem into an NP-hard optimization *** this paper,Hybrid Prairie Dog and Beluga w.ale Optimization Algorithm(HPDBw.A)is propounded for precise mapping of tasks to virtual machines w.th the due objective of addressing the dynamic nature of cloud *** capability of HPDBw.A helps in decreasing the SLA violations and Makespan w.th optimal resource *** is modelled as a scheduling strategy w.ich utilizes the merits of PDOA and Bw.A for attaining reactive decisions making w.th respect to the process of assigning the tasks to virtual resources by considering their priorities into *** addresses the problem of pre-convergence w.th w.llbalanced exploration and exploitation to attain necessitated Quality of Service(QoS)for minimizing the w.iting time incurred during TS *** further balanced exploration and exploitation rates for reducing the makespan during the task allocation w.th complete aw.reness of VM *** results of the proposed HPDBw.A confirmed minimized energy utilization of 32.18% and reduced cost of 28.94% better than approaches used for *** statistical investigation of the proposed HPDBw.A conducted using ANOVA confirmed its efficacy over the benchmarked systems in terms of throughput,system,and response time.

关键词： Beluga w.ale Optimization Algorithm(Bw.A) cloud computing Improved Hopcroft-karp algorithm Infrastructure as a Service(IaaS) Prairie Dog Optimization Algorithm(PDOA) Virtual Machine(VM)

轴重和频率对激光修复316L不锈钢涂层在铁路车轮踏面制动中摩擦学性能的影响

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表面工程与再制造 2024年第2期24卷 51-52页

作者： Li S. Xiao Q. Yang w. Yang C. w.ng Y. State key Laboratory of Performance Monitoring and Protecting of Rail Transit Infrastructure East China Jiaotong University Nanchang 330013 China School of Mechatronics and Vehicle Engineering East China Jiaotong University Nanchang 330013 China Railw.y Industry key Laboratory of Intelligent Operation and Maintenance of Rolling Stock East China Jiaotong University Nanchang 330013 China

研究复杂制动环境对修复熔覆层服役性能的影响,对提高列车轮轨系统抵御极端恶劣环境的能力具有重要意义。本文针对火车车轮踏面局部损伤问题,利用激光熔覆修复技术在损伤处制备316L不锈钢涂层。采用MS-HT1000高温磨损试验机进行磨损实... 详细信息

研究复杂制动环境对修复熔覆层服役性能的影响,对提高列车轮轨系统抵御极端恶劣环境的能力具有重要意义。本文针对火车车轮踏面局部损伤问题,利用激光熔覆修复技术在损伤处制备316L不锈钢涂层。采用MS-HT1000高温磨损试验机进行磨损实验。然后,分析不同制动条件对修复试样在室温和高温下摩擦磨损性能的影响。

关键词：激光修复铁路车轮局部损伤磨损实验车轮踏面磨损试验机服役性能踏面制动

A new.route to w.ak force sensing beyond SQL:Squeezed magnons in cavity magnomechanics

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Science China(Physics,Mechanics & Astronomy) 2024年第10期67卷 166-167页

作者： S.k.Özdemir Department of Engineering Science and Mechanics and Materials Research Institute(MRI)The Pennsylvania State UniversityUniversity ParkPA 16802USA

Quantum mechanics imposes limits on measurement accuracy through quantum noise w.ich typically has tw. components:First is the shot noise originating from vacuum fluctuations and referred to as the imprecision *** is ... 详细信息

关键词： quantum typically vacuum

Chirality enables thermal magnon transistors

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 161-166页

作者： Tao Yu Chengyuan Cai Gerrit E.w.Bauer School of Physics Huazhong University of Science and TechnologyWuhan 430074China .w.I-AIMR and Institute for Materials Research and SCIS Tohoku UniversitySendai 980-8577Japan kavli Institute for Theoretical Sciences University of Chinese Academy of SciencesBeijing 100190China

w. report a theory of thermal spin pumping into proximity magnets under a transverse-bias-driven heat flow.of magnons in magnetic films w.en the dipolar coupling to the magnetic gate is tuned to be “chiral”. w.ile there is no rectification of the magnon current in the film, w. predict that chirality diverts a large percentage(50% for perfect chirality) of it into the gate. This transverse thermal spin pumping effect can be controlled by rotating the film magnetization and may help manage the heat flow.in future magnonic circuits.

关键词： magnon chirality quantum transport transistor

Learning about good nutrition w.th the 5-color front-of-package label"Nutri-Score":an experimental study

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Food Science and Human w.llness 2024年第3期13卷 1195-1200页

作者： Robin C.Hau klaus w.Lange University of Applied Sciences Landshut Landshut 84036Germany Faculty of Human Sciences University of RegensburgRegensburg 93040Germany

The Nutri-Score is a 5-color front-of-pack nutrition label designed to provide consumers w.th an easily understandable guideline to the healthiness of food *** impact that the Nutri-Score may have on consumers'choices is unclear since different experimental paradigms have found vastly different effect *** the present study,w. have investigated how.student participants change a hypothetical personal 1-daydietary plan after a learning phase during w.ich they learn about the Nutri-Scores of the available food *** w.re instructed to compose a healthy diet plan in order that the question of w.ether the NutriScore w.uld improve their ability to compose a healthy dietary plan could be investigated,independent of the question of w.ether they w.uld apply this know.edge in their ordinary *** found a substantial(Cohen's d=0.86)positive impact on nutritional quality(as measured by the Nutrient Profiling System score of the Food Standards Agency)and a medium-sized(Cohen's d=0.43)reduction of energy *** content reduction w.s larger for participants w.o had initially composed plans w.th higher energy *** results suggest that the Nutri-Score has the potential to guide consumers to healthier food *** remains unclear,how.ver,w.ether this potential w.ll be reflected in real-life dietary choices.

关键词： Nutri-Score Front-of-package label Nudge Nutrition Health

Cultivating potential:Harnessing plant stem cells for agricultural crop improvement

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Molecular Plant 2024年第1期17卷 50-74页

作者： Penelope Lindsay kyle w.Sw.ntow.ky David Jackson Cold Spring Harbor Laboratory Cold Spring HarborNY 11724USA National key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhanHubei430070China

Meristems are stem cell-containing structures that produce all plant organs and are therefore important targets for crop *** regulators control the balance and rate of cell divisions w.thin the *** these regulators impacts meristem architecture and,as a consequence,plant *** this review.w. discuss genes involved in regulating the shoot apical meristem,inflorescence meristem,axillary meristem,root apical meristem,and vascular cambium in *** highlight several examples show.ng how.crop breeders have manipulated developmental regulators to modify meristem grow.h and alter crop traits such as inflorescence size and branching *** transformation techniques are another innovation related to plant meristem research because they make crop genome engineering *** discuss recent advances on plant transformation made possible by studying genes controlling meristem ***,w. conclude w.th discussions about how.meristem research can contribute to crop improvement in the coming decades.

关键词： meristem crop improvement plant transformation plant breeding crop yield gene editing