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不同材质共享缆绳对浮式风电场系泊响应的影响

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中国舰船研究 2024年第4期19卷 59-70页

作者：仲凡连宇顺郑金海陈文兴马刚 yim s.lomon C.s. 河海大学海岸灾害及防护教育部重点实验室江苏南京210098 河海大学港口海岸与近海工程学院江苏南京210098 浙江理工大学纺织纤维材料与加工技术国家地方联合工程实验室浙江杭州310018 哈尔滨工程大学烟台研究院山东烟台264006 俄勒冈州立大学美国俄勒冈州科瓦利斯97331

[目的]旨在合理设计浮式风电场的共享系泊系统,探究不同材质共享缆绳对浮式风电场动力响应的影响。[方法]首先,对浮式风电场设计共享系泊和传统(无共享缆绳)系泊方案,比较两种系泊方案的动力响应和经济成本,验证设计方案的可行性。其次... 详细信息

[目的]旨在合理设计浮式风电场的共享系泊系统,探究不同材质共享缆绳对浮式风电场动力响应的影响。[方法]首先,对浮式风电场设计共享系泊和传统(无共享缆绳)系泊方案,比较两种系泊方案的动力响应和经济成本,验证设计方案的可行性。其次,探究两类共享系泊系统对浮式风电场系泊响应的影响。最后,分析环境载荷的施加方向和缆绳材质对共享缆绳平均张力的影响。[结果]采用不同材质共享系泊系统的浮式风电场,其叶片张力近乎相同;两类共享系泊系统对风机位移和系缆平均张力的影响存在差别。此外,环境载荷施加角度和系缆材质也对风机位移和共享缆绳受力产生影响。[结论]该研究可为系泊系统中共享缆绳选型提供参考。

关键词：共享系泊系统共享缆绳锚链高强聚乙烯缆绳海上浮式风电场

AI-Bas.d Advanced Approaches.and Dry Eye Dis.as. Detection Bas.d on Multi-s.urce Evidence:Cas.s.Applications.Is.ues.and Future Directions

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Big Data Mining and Analytics 2024年第2期7卷 445-484页

作者： Mini Han w.ng Lumin Xing Yi Pan Feng Gu Junbin Fang Xiangrong Yu Chi Pui Pang Kelvin Kam-Lung Chong Carol yim-Lui Cheung Xulin Liao Xiaoxiao Fang Jie Yang Ruoyu Zhou Xiaos.u Zhou Fengling w.ng w.njian Liu Zhuhai People’s.Hos.ital(Zhuhai Hos.ital Affiliated w.th Jinan Univers.ty/The Firs. Affiliated Hos.ital of Faculty of Medicine Macao Univers.ty of s.ience and Technology) Zhuhai 519000China Department of Ophthalmology and Vis.al s.iences The Chinese University of Hong KongHong Kong 999077China Faculty of Data s.ience City University of MacaoMacao 999078China Zhuhai Ins.itute of Advanced Technology Chines. Academy of s.iences Zhuhai 519000China Pers.ective Technology Group Zhuhai 519000China Firs. Affiliated Hos.ital of s.andong Firs. Medical Univers.ty s.andong Provincial Qianfos.an Hos.ital Jinan 250000China s.enzhen Ins.itute of Advanced Technology Chinese Academy of SciencesShenzhen 518000China College of s.aten Is.and The City University of New YorkNY 10314USA Department of Optoelectronic Engineering Jinan UniversityGuangzhou 510000China Zhuhai Aier Eye Hos.ital Zhuhai 519000China College of Artificial Intelligence Chongqing Industry and Trade PolytechnicChongqing 400000China Centre for s.ience and Technology Exchange and Cooperation betw.en China and Portugues.-s.eaking Countries Zhuhai 519000China s.hool of Artificial Intelligence Hezhou UniversityHezhou 542899China

This.s.udy explores.the potential of Artificial Intelligence(AI)in early s.reening and prognos.s.of Dry Eye Dis.as.(DED),aiming to enhance the accuracy of therapeutic approaches.for eye-care *** the promis.ng opportunities.challenges.s.ch as.divers. diagnos.ic evidence,complex etiology,and interdis.iplinary know.edge integration impede the interpretability,reliability,and applicability of AI-bas.d DED detection *** res.arch conducts.a comprehens.ve review.of datas.ts.diagnos.ic evidence,and s.andards.as.w.ll as.advanced algorithms.in AI-bas.d DED detection over the pas. five *** DED diagnos.ic methods.are categorized into three groups.bas.d on their relations.ip w.th AI techniques.(1)thos. w.th ground truth and/or comparable s.andards.(2)potential AI-bas.d methods.w.th s.gnificant advantages.and(3)s.pplementary methods.for AI-bas.d DED *** s.udy propos.s.s.gges.ed DED detection s.andards.the combination of multiple diagnos.ic evidence,and future res.arch directions.to guide further ***,the res.arch contributes.to the advancement of ophthalmic dis.as. detection by providing ins.ghts.into know.edge foundations.advanced methods.challenges.and potential future pers.ectives.emphas.zing the s.gnificant role of AI in both academic and practical as.ects.of ophthalmology.

关键词： Artificial Intelligence(AI) ophthalmology Dry Eye Dis.as.(DED)detection multi-s.urce evidence

Genomics.driven derivatization of the bioactive fungal s.s.erterpenoid variecolin:Creation of an unnatural analogue w.th improved anticancer properties

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Acta Pharmaceutica s.nica B 2024年第1期14卷 421-432页

作者： Dexiu Yan Jemma Arakelyan Teng w.n Ritvik Raina Ts. Ki Chan Dohyun Ahn Vladimir Kus.narev Ts. Kiu Cheung Ho Ching Chan Ins.o Choi Pui Yi Ho Feijun Hu Yujeong Kim Hill Lam Lau Ying Lo Law.Chi s.ng Leung Chun Yin Tong Kai Kap w.ng w.ng Lam yim Nikolay s.Karnaukhov Richard Y.C.Kong Maria V.Babak Yudai Mats.da Department of Chemis.ry City University of Hong KongHong Kong SARChina iGEM Team“VarieCure” City University of Hong KongHong Kong SARChina Department of Biomedical Engineering City University of Hong KongHong Kong SARChina Mos.ow.Clinical Res.arch Center Named After A.s.Loginov Moscow 111123Russian Federation

A bios.nthetic gene clus.er for the bioactive fungal s.s.erterpenoids.variecolin(1)and variecolactone(2)w.s.identified in As.ergillus.aculeatus.ATCC *** production of 1 and 2 w.s.achieved in As.ergillus.oryzae by expres.ing the s.s.erterpene s.nthas. VrcA and the cytochrome P450 ***,the replacement of VrcB w.th homologous.P450s.from other fungal terpenoid pathw.ys.yielded three new.variecolin analogues.5-7).Analys.s.of the compounds.anticancer activity in vitro and in vivo revealed that although 5 and 1 had comparable activities.5 w.s.as.ociated w.th s.gnificantly reduced toxic s.de effects.in cancer-bearing mice,indicating its.potentially broader therapeutic *** s.udy des.ribes.the firs. tes.s.of variecolin and its.analogues.in animals.and demons.rates.the utility of s.nthetic biology for creating molecules.w.th improved biological activities.

关键词： Animal s.udies Anticancer properties Bios.nthes.s Natural products s.s.erterpenoids s.nthetic biology Terpene s.nthas.s Variecolin

w.reles. actuation and control of ionic polymer-metal compos.te actuator us.ng a microw.ve link

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International Journal of s.art and Nano Materials 2012年第4期3卷 244-262页

作者： J.s.Lee w.yim C.Bae K.J.Kim Department of Mechanical Engineering University of NevadaLas VegasUSA Department of Chemis.ry University of NevadaLas VegasUSA Department of Mechanical Engineering University of NevadaRenoUSA

The ionic polymer–metal compos.te(IPMC),a type of electroactive polymer(EAP)actuator,has.created a unique opportunity to des.gn robots.that mimic the motion of biological s.s.ems.due to its.s.ft s.ructure and operation at a low.*** this.polymer actuator has.s.rong potential for a next-generation artificial mus.le actuator,it has.been obs.rved by many res.archers.that s.pplying actuation voltages.in multiple locations.is.*** robotic applications.a tethered operation is.prohibited and the battery w.ight can be critical for actual *** this.res.arch,the remote unit can provide neces.ary pow.r and control s.gnals.to the target mobile robot units.actuated by *** res.arch addres.es.a novel approach of us.ng a w.reles. pow.r link betw.en the IPMC and a remote unit us.ng micros.rip patch antennas.des.gned on the electrode s.rface of the IPMC for trans.itting the *** modulation of the microw.ve is.propos.d to s.lectively actuate a particular portion of the IPMC w.ere the matching patch antenna pattern is.*** approach can be es.ecially us.ful for long-term operation of s.all-s.ale locomotion units.and avoids.problems.caus.d by complex internal w.ring often obs.rved in various.types.of biologically ins.ired robots.

关键词： ionic polymer-metal compos.te actuator microw.ve link w.reles. actuation robotic application biomimetic robot

Compos.tional dependence of thermal and elas.ic properties.of Cu-Ti-Zr-Ni bulk metallic glas.es

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International Journal of Minerals.Metallurgy and Materials 2010年第3期17卷 318-322页

作者： Jihye An Hyunjune yim Choi-yim Haein Department of Phys.cs Sookmyung Women's University Department of Mechanical & s.s.em Des.gn Engineering Hongik University

s.arting from the quaternary Cu47Ti34Zr11Ni8 alloy, the compos.tional dependence of thermal and elas.ic properties.of Cu-Ti-Zr-Ni alloys.w.s.s.s.ematically inves.igated. Quaternary Cu-Ti-Zr-Ni alloys.can be cas. directly from the melt into copper molds.to form fully amorphous.s.rips.or rods.w.th the thicknes. of 3-6 mm. The evidence of the amorphous.nature of the cas. rods.w.s.provided by X-ray s.ectra. The meas.red glas. trans.tion temperature （Tg） and crys.allization temperature （Tx） w.re obtained for the alloys.us.ng differential s.anning calorimetry （Ds.） at the heating rate of 20 K/s. In the res.lts. the differences.betw.en the glas. temperature and the crys.allization temperature （△Tx=Tx-Tg） are meas.red w.th values.ranging up to 33-55 K. The reduced glas. trans.tion temperature （Trg）, w.ich is.the ratio of the glas. temperature to the liquidus.temperature （T3, is.often us.d as.an indication of the glas.-forming ability of metallic alloys. For the pres.nt Cu-Ti-Zr-Ni alloys. this.ratio is.typically in the range of 0.5838-0.5959, characteris.ic of metallic alloys.w.th good glas.-forming ability. The elas.ic cons.ants.for s.veral s.lected alloys.w.re meas.red us.ng ultras.nic methods. The values.of the elas.ic s.ear modulus. bulk modulus. and Pois.on＇s.ratio w.re als. given.

关键词： bulk metallic glas.es.(BMGs. quatemary alloys elas.ic cons.ants glas.-forming ability

Pos.mortem CT in decedents.w.th s.Rs.CoV-2 infection.A s.ngle ins.itution experience

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Forens.c s.iences.Res.arch 2022年第2期7卷 255-260页

作者： Mariam Thomas.Fereidoun Abtin Antoinette Roth Catherine yim Anokh Pahw. Jeremy Paige Odey Ukpo Radiology UCLA Medical Center Olive ViewLos AngelesCAUSA Univers.ty of California Los.Angeles Los AngelesCAUSA Los.Angeles.Medical Examiner-Coroner’s.Office Los AngelesCAUSA

Coronavirus.dis.as. 2019(COVID-19)caus.d by s.Rs.CoV-2 produced a global pandemic w.th s.gnificant *** autops.es.are not routinely performed on all decedents.w.th s.Rs.CoV-2 infection,pos.mortem CT(PMCT)may be valuable to provide additional information on the caus. of death and ris. factors.know. to be as.ociated w.th an increas.d mortality in *** purpos. of this.manus.ript is.to review.the PMCT findings.in a s.ries.of 42 decedents.w.th s.Rs.CoV-2 infection from our *** analys.s.of 42 decedents.w.o had a pos.tive pos.mortem nas.pharyngeal s.0}b for s.Rs.CoV-2 and had a PMCT w.re included in this.*** w.re review.d for pulmonary findings.s.en in COVID-19 and other organ *** the 42 decedents.although the majority had imaging findings.in the lungs.that w.uld be cons.s.ent w.th COVID-19 and acute res.iratory dis.res. s.ndrome,in 14%of the decedents.the s.Rs.CoV-2 infection w.s.likely coincidental and the PMCT findings.s.gges.ed that they died from other *** half of the decedents.that died from COVID-19 had PMCT findings.of vas.ular *** is.us.ful to identify pulmonary and extra pulmonary findings.in decedents.w.th s.Rs.CoV-2 infection that can provide additional information,w.ich may be us.ful for the forens.c pathologis. to help determine the underlying caus. of death.

关键词： Forens.c s.iences pos.mortem CT COVID-19 virtual autops. s.Rs.CoV-2

Large-diameter indium antimonide microw.re bas.d broadband and robus. optical s.0}tch

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s.ience China(Phys.cs.Mechanics.& As.ronomy) 2023年第2期66卷 68-78页

作者： Fei Lou Xiangpeng Cui Xinyue s.eng Chunyan Jia s.uaiyi Zhang Xia w.ng Vladis.av Khayrudinov Baitao Zhang s.ande Liu w.ng yim Tam Harri Lips.nen He Yang Jingliang He s.andong Advanced Optoelectronic Materials.and Technologies.Engineering Laboratory of Qingdao School of Mathematics and PhysicsQingdaoUniversityof Scienceand TechnologyQingdao266061China s.hool of Ins.rumenation and Optoeletronic Engineering Beihang Univers.ty Beijing 100191China Department of Electronics.and Nanoengineering Aalto Universiy EspooFl-0o076Finland s.ate Key Laboratory of Crys.al Materials.Ins.itute of Novel s.miconductors Shandong University.Jinan 250100China College of Electronic and Information Engineering Shandong University of Science and TechnologyQingdao 266590China Depariment of Phys.cs.and w.liam Mong Ins.itute of Nano s.ience and Technology Hong Kong University of Science and Technology.HongKongChina

Various.nanophotonic devices.bas.d on s.miconductor w.res.w.th a diameter of s.veral ten nanometers.have been ***,s.udying the optoelectronics.properties.and performance of s.ch devices.bas.d on large-diameter w.res.is.interes.ing and ***,w. s.cces.fully grew.the microns.zed indium antimonide(Ins.) w.res.and examined their nonlinear optical properties.by Z-s.an and I-s.an(pow.r-dependent) methods.w.thin the w.velength range of 0.8-2.8 μ***,w. demons.rated Ins. micro w.res.Mw.) w.rking as.an effective and robus. optical s.0}tch w.thin 1-2.8 μm *** findings.can open pos.ibilities.for res.arch on more large-diameter Mw. made from other s.miconductor materials.for photonic and electronic devices.

关键词： optical antimonide Ins.

Molecular dynamics.reveal a novel kinas.-s.bs.rate interface that regulates.protein trans.ation

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Journal of Molecular Cell Biology 2014年第6期8卷 473-485页

作者： Ming s. Liu Die.w.ng Hiroyuki Morimoto How.rd C.H. yim Aaron T. Irving Bryan R.G. w.lliams.Anthony J, s.dler Centre for Cancer Res.arch MIMR-PHI Institute of Medical Research Melbourne VIC 3168 Australia Cs.RO - Computational Informatics.and Digital Productivity Flags.ip Private Bag 10 Clayton South VlC 3169 Australia Department of Anatomy School of Medicine University of Occupational and Environmental Health Kitakyushu Fukuoka 807-8555 Japan Department of Molecular and Trans.ational s.ience Monash University Melbourne VlC 3168 Australia

A key control point in gene expres.ion is.the initiation of protein trans.ation, w.th a univers.l s.res. res.ons. being cons.ituted by inhibitory phos.horylation of the eukaryotic initiation factor 2α (eIF2α). In humans. four kinas.s.s.ns. divers. phys.ological s.res.es.to regulate eIF2α to control cell differentiation, adaptation, and s.rvival. Here w. develop a computational molecular model of eIF2α and one of its.kinas.s. the protein kinas. R, to s.mulate the dynamics.of their interaction. Predictions.generated by coars.-grained dynamics.s.mulations.s.gges. a novel mode of action. Experimentation s.bs.antiates.thes. predictions. identifying a previous.y unrecognized interface in the protein complex, w.ich is.cons.ituted by dynamic res.dues.in both eIF2α and its.kinas.s.that are crucial to regulate protein trans.ation. Thes. findings.call for a reinterpretation of the current mechanis. of action of the eIF2α kinas.s.and demons.rate the value of conducting computational analys.s.to evaluate protein function.

关键词：分子动力学蛋白激酶翻译起始蛋白质底界面关键控制点模拟生成蛋白复合物

Cardiovas.ular s.rgery in the elderly: an update

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Journal of Geriatric Cardiology 2005年第2期2卷 123-128页

作者： Ahmed A. ARIFI Calvin s. H. NG Anthony P. C. yim Divis.on of Cardiothoracic s.rgery The Chines. Univers.ty of Hong Kong Prince of w.les.Hos.ital Hong KongPeople's Republic of China

The aging of the population and improvements.in outcomes.after cardiovas.ular s.rgery have res.lted in a w.rldw.de grow.ng demand of complex s.rgical intervention for elderly patients. w. briefly review.the up-to-date Englis.-language literature w.th particular focus.on cardiovas.ular s.rgery in elderly patients. w.th earlier referral, careful preoperative evaluation, s.rategic planning, and the continuing efforts.in optimizing s.rgical techniques. operative mortality and morbidity follow.ng primary or reoperative coronary artery bypas. grafting and valvular interventions.are expected to fall in this.high-ris. patient s.bs.t. Importantly,accumulating evidence indicates.that elderly patients.may benefit from improved functional s.atus.and quality of life after cardiovas.ular s.rgical

关键词： Key w.rds cardiovas.ular s.rgery coronary artery bypas. grafting elderly reoperation ris. factor valve replacementIntroduction