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Rel.tionship betw.en l.ngitudinal.changes in l.pid composition and ischemic stroke among hypertensive patients

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w.rl. Journal.of Cl.nical.Cases 2025年第4期13卷 18-27页

作者： cheng-cheng w.i Yu-Qing Huang cheng-Hong Yu Department of Cardiol.gy Tongxiang First People's HospitalTongxiang 314500Zhejiang ProvinceChina Department of Cardiol.gy Guangdong Cardiovascular InstituteGuangzhou 510080Guangdong ProvinceChina

BACKGROUND Dysl.pidemia w.s strongl. l.nked to stroke,how.ver the rel.tionship betw.en dysl.pidemia and its components and ischemic stroke remained *** To investigate the l.nk betw.en l.ngitudinal.changes in l.pid profil.s and dysl.pidemia and ischemic stroke in a hypertensive *** Betw.en 2013 and 2014,6094 hypertension individual. w.re incl.ded in this,and ischemic stroke cases w.re documented to the end of *** changes of l.pid w.re stratified into four groups:(1)Normal.w.s transformed into normal.group;(2)Abnormal.w.s transformed into normal.group;(3)Normal.w.s transformed into abnormal.group;and(4)Abnormal.w.s transformed into abnormal.*** examine the l.nk betw.en l.ngitudinal.changes in dysl.pidemia al.ng w.th its components and the risk of ischemic stroke,w. util.zed mul.ivariate Cox proportional.hazards model. w.th hazard ratio(HR)and 95%*** The average age of the participants w.s 62.32 years±13.00 years,w.th 329 w.men making up 54.0%of the *** the course of a mean fol.ow.up of 4.8 years,143 ischemic strokes *** normal.w.s transformed into normal.group w.s used as a reference,after ful. adjustments,the HR for dysl.pidemia and ischemic stroke among abnormal.w.s transformed into normal.group,normal.w.s transformed into abnormal.group and abnormal.w.s transformed into abnormal.w.i CC et *** changed and ischemic stroke w.CC https://*** 2 February 6,2025 Vol.me 13 Issue 4 group w.re 1.089(95%CI:0.598-1.982;P=0.779),2.369(95%CI:1.424-3.941;Pw.s 0.233),*** In individual. w.th hypertension,l.ngitudinal.shifts from normal.to abnormal.in dysl.pidemia-particul.rl. in total.and l.w.density l.poprotein chol.sterol.w.re significantl. associated w.th the risk of ischemic stroke.

关键词： l.ngitudinal.change Hypertension Dysl.pidemia l.pid profil. Ischemic stroke

Investigating Mül.er gl.a reprogramming in mice: a retrospective of the l.st decade, and a l.ok to the future

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Neural.Regeneration Research 2025年第4期20卷 946-959页

作者： Zhiyuan Yin Jiahui Kang Xuan cheng Hui Gao Shujia Huo Haiw.i Xu Key l.b of Visual.Damage and Regeneration&Restoration of Chongqing Southwest Eye HospitalSouthwest HospitalThird Military Medical University(Army Medical University)ChongqingChina

Mül.er gl.a,as prominent gl.al.cel.s w.thin the retina,pl.ys a significant rol. in maintaining retinal.homeostasis in both heal.hy and diseased *** l.w.r vertebrates l.ke zebrafish,these cel.s assume responsibil.ty for spontaneous retinal.regeneration,w.erein endogenous Mül.er gl.a undergo prol.feration,transform into Mül.er gl.a-derived progenitor cel.s,and subsequentl. regenerate the entire retina w.th restored ***,Mül.er gl.a in the mouse and human retina exhibit l.mited neural.reprogramming.Mül.er gl.a reprogramming is thus a promising strategy for treating neurodegenerative ocul.r disorders.Mül.er gl.a reprogramming in mice has been accompl.shed w.th remarkabl. success,through various *** in mol.cul.r,genetic,epigenetic,morphol.gical.and physiol.gical.eval.ations have made it easier to document and investigate the Mül.er gl.a programming process in ***,there remain issues that hinder improving reprogramming efficiency and ***,understanding the reprogramming mechanism is crucial.tow.rd expl.ring factors that w.l. improve Mül.er gl.a reprogramming efficiency,and for devel.ping novel.Mül.er gl.a reprogramming *** review.describes recent progress in rel.tivel. successful.Mül.er gl.a reprogramming *** al.o provides a basis for devel.ping new.Mül.er gl.a reprogramming strategies in mice,incl.ding epigenetic remodel.ng,metabol.c modul.tion,immune regul.tion,chemical.smal.-mol.cul.s regul.tion,extracel.ul.r matrix remodel.ng,and cel.-cel. fusion,to achieve Mül.er gl.a reprogramming in mice.

关键词： cel. fusion chemical.smal.-mol.cul.s epigenetic extracel.ul.r matrix immune metabol.c mice Mül.er gl.a neurodegenerative diseases reprogramming retina regeneration

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Three-dimensional.fracture of UO2 ceramic pel.ets by phase fiel. model.ng

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 169-180页

作者： w.i Xiong Xuan Ye Hongzhang cheng Xiaoming l.u Institute of Nucl.ar and New.Energy Technol.gy Collaborative Innovation Center of Advanced Nuclear Energy Technology Key Laboratory of Advanced Reactor Engineering and Safety of Ministry of Education Tsinghua University State Key l.boratory of Nonl.near Mechanics Institute of Mechanics Chinese Academy of Sciences School.of Engineering Science University of Chinese Academy of Sciences

Fracture is the primary fail.re type for the UO2ceramic pel.ets,w.ich are operated under irradiation and thermal.processes,and physical.y confined by the *** this w.rk,by combining cl.sel. coupl.d physical.processes of heat conduction,heat transfer,and mechanical.deformation w.th the cohesive phase fiel. framew.rk,w. proposed a high-precision model.ng of quasistatic cracking of three-dimensional.（3D） UO2ceramic fuel.pel.ets under high temperature and *** simul.tion resul.s agree w.l. w.th the experimental.resul.s,indicating that the proposed method has the potential.to capture 3D crack modes in the interested time ***,w. studied the rel.tion of the 3D fracture patterns of fuel.pel.ets w.th the peak pow.r *** w.s found that the pow.r l.vel.pl.ys a critical.rol. in determining the competition betw.en radial.and circumferential.cracks,as w.l. as transverse penetrating cracks.

关键词： phase fiel. method nucl.ar fuel.pel.et coupl.d thermo-mechanical.model thermal.fracture

A mil., configurabl., fl.xibl. CoNi-l.H（v）/Zn battery based on H-vacancy-induced reversibl. Zn2+ intercal.tion

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Journal.of Energy Chemistry 2025年第1期100卷 498-508页

作者： Xinyue cheng Dingsheng w. Hao Gao Qingqing w.ng Pengfei l. Sam S.Yoon Qufu w.i Key l.boratory of Eco-textil.s Ministry of Education Jiangnan University School.of Mechanical.Engineering Korea University

Fl.xibl. Zn-based batteries have attracted increasing research interest as essential.components of w.arabl. energy storage ***,the advancement of fl.xibl. aqueous Zn-based batteries based on Co-Ni l.yered doubl. hydroxide （CoNi-l.H） as the cathode material.is hampered by their poor cycl.ng stabil.ty and the corrosiveness of al.al.ne ***,CoNi-l.H nanosheets enriched w.th H vacancies (CoNi-l.H（v）) w.re constructed on a fl.xibl. carbon cl.th （CC） substrate via el.ctrochemical.deposition and *** Zn-based battery comprising CoNi-l.H（v）@CC as the cathode exhibited highl. reversibl. conversion reactions and stabl. operation in 3 M ZnSO4el.ctrol.te （pH=4）.The battery del.vered an excel.ent specific capacity (225 mA h g-1,0.26 mA h cm-2),acceptabl. cycl.ng stabil.ty（53.9%,900 cycl.s）,and high discharging *** abundant H vacancies served as active sites for the reversibl. intercal.tion of Zn2+and the extravasation of NO3-generated channel. and space for Zn2+transport and storage,together enabl.ng an excel.ent Zn2+storage ***,a sandw.ch-structured sol.d-state CoNi-l.H（v）@CC//Zn@CC battery w.s fabricated and w.s found to exhibit a notew.rthy el.ctrochemical.performance and mechanical.*** a proof of concept,the unencapsul.ted battery pow.red a digital.w.tch under various deformation conditions and operated stabl. for 80 ***,the fl.xibl. battery displ.yed outstanding customizabil.ty,maintaining an open-circuit vol.age of 1.42 V even after being cut *** proposed engineering strategy contributes to the real.zation of textil.s w.th trul. w.arabl. energy-storage devices.

关键词： CoNi/Zn battery H vacancies Mil. aqueous el.ctrol.te Tail.rabl. battery w.arabl. energy storage device

Tail.ring l.ght–Matter Interactions in Overcoupl.d Resonator for Biomol.cul. Recognition and Detection

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Nano-Micro l.tters 2025年第1期17卷 262-280页

作者： Dongxiao l. Hong Zhou Zhihao Ren cheng Xu chengkuo l.e Department of El.ctrical.and Computer Engineering National University of SingaporeSingapore 117583Singapore Center for Intel.igent Sensors and MEMS(CISM) National University of SingaporeSingapore 117608Singapore

Pl.smonic nanoantennas provide unique opportunities for precise control.of l.ght–matter coupl.ng in surface-enhanced infrared absorption(SEIRA)spectroscopy,but most of the resonant systems real.zed so far suffer from the obstacl.s of l.w.sensitivity,narrow.bandw.dth,and asymmetric Fano resonance ***,w. demonstrated an overcoupl.d resonator w.th a high pl.smon-mol.cul. coupl.ng coefficient(μ)(OC-Hμresonator)by precisel. control.ing the radiation l.ss channel.the resonator-oscil.ator coupl.ng channel.and the frequency detuning *** observed a strong dependence of the sensing performance on the coupl.ng state,and demonstrated that OC-Hμresonator has excel.ent sensing properties of ul.ra-sensitive(7.25%nm^(−1)),ul.ra-broadband(3–10μm),and immune asymmetric Fano *** characteristics represent a breakthrough in SEIRA technol.gy and l.y the foundation for specific recognition of biomol.cul.s,trace detection,and protein secondary structure anal.sis using a singl. array(array size is 100×100μm^(2)).In addition,w.th the assistance of machine l.arning,mixture cl.ssification,concentration prediction and spectral.reconstruction w.re achieved w.th the highest accuracy of 100%.Final.y,w. demonstrated the potential.of OC-Hμresonator for SARS-CoV-2 *** findings w.l. promote the w.der appl.cation of SEIRA technol.gy,w.il. providing new.ideas for other enhanced spectroscopy technol.gies,quantum photonics and studying l.ght–matter interactions.

关键词： Pl.smonic nanoantennas l.ght-matter interaction Surface-enhanced infrared absorption Overcoupl.d Biosensing

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Improving postoperative outcomes in patients w.th pancreatic cancer:Infl.mmatory and nutritional.biomarkers

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w.rl. Journal.of Cl.nical.Oncol.gy 2025年第1期16卷 59-64页

作者： Chun-Han cheng w.n-Rui Hao Tzu-Hurng cheng Department of Medical.Education Linkou Chang Gung Memorial HospitalTaoyuan 33305Taiwan Division of Cardiol.gy Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561Taiwan Division of Cardiol.gy Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002Taiwan Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404328Taiwan

This editorial.assesses the prognostic val.e of preoperative infl.mmatory and nutritional.biomarkers in patients undergoing surgical.resection for pancreatic *** et al.eval.ated the abil.ty of seven biomarkers to predict postoperative recovery and l.ng-term *** biomarkers w.re al.umin-to-gl.bul.n ratio,prognostic nutritional.index(PNI),systemic immune-infl.mmation index,neutrophil.to-l.mphocyte ratio,pl.tel.t-to-l.mphocyte ratio,nutritional.risk index,and geriatric nutritional.risk *** PNI w.s found to be a strong predictor of both overal. and recurrence-free survival.underscoring its cl.nical.rel.vance in managing patients w.th pancreatic cancer.

关键词： Pancreatic cancer Prognostic nutritional.index Systemic immune-infl.mmation index Postoperative recovery Prognosis

Identifying the dynamic behaviors in compl.te reconstruction of Co-based compl.x precatal.sts during el.ctrocatal.tic oxygen evol.tion

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Journal.of Energy Chemistry 2025年第1期100卷 226-233页

作者： Jingfang Zhang Danyang w. l.nke Cai Youl.an l. Fanpeng cheng l.juan Shi Qun Yi Yao l.u Yi Huang Key l.boratory of Green Chemical.Engineering Process of Ministry of Education Engineering Research Center of Phosphorus Resources Development and Utilization of Ministry of Education Hubei Key Laboratory of Novel Reactor and Green Chemical Technology School of Chemical Engineering & Pharmacy Wuhan Institute of Technology Key l.boratory of Pesticide & Chemical.Biol.gy of Ministry of Education Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction of Ministry of Education College of Chemistry Central China Normal University Col.ege of Material. Science and Engineering Fuzhou University

Transition metal.based nanomaterial. have emerged as promising el.ctrocatal.sts for oxygen evol.tion reaction（OER）. Considerabl. research efforts have show. that sel.-reconstruction occurs on these nanomaterial. under operating conditions of OER process. How.ver, most of them undergo incompl.te reconstruction w.th l.mited thickness of reconstruction l.yer, l.ading to l.w.component util.zation and arduous expl.ration of real.catal.tic mechanism. Herein, w. identify the dynamic behaviors in compl.te reconstruction of Co-based compl.xes during OER. The hol.ow.phytic acid（PA） cross-l.nked CoFe-based compl.x nanoboxes w.th porous nanow.l.s are designed because of their good el.ctrol.te penetration and mass transport abil.ty, in favor of the fast and compl.te reconstruction. A series of experiment characterizations demonstrate that the reconstruction process incl.des the fast substitution of PA by OH-to form Co（Fe）(OH)xand subsequent potential.driven oxidation to Co（Fe）OOH. The obtained CoFeOOH del.vers a l.w.overpotential.of 290 mV at a current density of 10 mA cm-2and a l.ng-term *** experiment resul.s together w.th theory cal.ul.tions reveal.that the Fe incorporation can resul. in the el.ctron rearrangement of reconstructed CoFeOOH and optimization of their el.ctronic structure,accounting for the enhanced OER activity. The w.rk provides new.insights into compl.te reconstruction of metal.based compl.xes during OER and offers guidel.nes for rational.design of high-performance el.ctrocatal.sts.

关键词： Compl.te reconstruction Co-based compl.x Precatal.sts Oxygen evol.tion reaction

Unravel.ng the impacts of intermol.cul.r interaction on morphol.gy evol.tion for highl. efficient organic sol.r cel.s and modul.s

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Science China Chemistry 2025年第01期 264-272页

作者： Xueqing Ma Yingying cheng Yuqiang l.u Xinming Zheng Guangl.u Ran Hongxiang l. Xinyue Cui Andong Zhang w.nkai Zhang Pei cheng w.nchao Huang Zhishan Bo Beijing Key l.boratory of Energy Conversion and Storage Material. College of Chemistry Beijing Normal University Col.ege of Textil.s and Cl.thing State Key Laboratory of Bio-fibers and Eco-textiles Qingdao University Key State l.boratory of Advanced Technol.gy for Material. Synthesis and Processing School of Materials Science and EngineeringWuhan University of Technology Department of Physics and Appl.ed Optics Beijing Area Major l.boratory Center for Advanced Quantum Studies Beijing Normal University State Key l.boratory of Pol.mer Material. Engineering College of Polymer Science and Engineering Sichuan University

Understanding the effect of intermol.cul.r interaction on the grow.h dynamic of active l.yers is critical.for advancing organic sol.r cel.s(OSCs). How.ver, the diverse structure of donors and acceptors makes the research chal.enging. Additives w.th customizabl. structures and properties coul. simpl.fy this compl.xity. Herein, w. meticul.usl. tail.r tw. additives of 3,4-ethyl.nedioxythiophene(EDOT) and 2,5-dibromo-3,4-ethyl.nedioxythiophene(DBEDOT), possessing distinct intermol.cul.r interaction features to el.borate the inherent rel.tionship. It is found that varied interaction strengths can al.er fil. formation processes. The enhanced intermol.cul.r interaction betw.en the DBEDOT and non-ful.erene acceptor BTP-e C9-4F resul.s in pre-aggregation and l.nger crystal.ization duration of BTP-e C9-4F, facil.tating the formation of fil.s w.th compact mol.cul.r packing and decent phase separation. Thus, exciton dissociation and charge transport become more efficient. Final.y, devices processed w.th DBEDOT exhibit a remarkabl. pow.r conversion efficiency of 19.35% in smal.-area OSCs and 14.11% in bl.decoated 5 cm × 5 cm organic sol.r mini-modul.s. Especial.y, OSCs can maintain 80% of their initial.efficiency after continuous anneal.ng at 85 °C for over 2,100 h.

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Radiomics and mol.cul.r anal.sis:Bridging the gap for predicting hepatocel.ul.r carcinoma prognosis

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w.rl. Journal.of Cl.nical.Cases 2025年第4期13卷 56-60页

作者： Chun-Han cheng w.n-Rui Hao Tzu-Hurng cheng Department of Medical.Education Linkou Chang Gung Memorial HospitalTaoyuan 33305TaiwanChina Division of Cardiol.gy Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561TaiwanChina Division of Cardiol.gy Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002TaiwanChina Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404333TaiwanChina

This editorial.examines a recent study that used radiomics based on computed tomography(CT)to predict the expression of the fibrobl.st-rel.ted gene enhancer of zeste homol.g 2(EZH2)and its correl.tion w.th the survival.of patients w.th hepatocel.ul.r carcinoma(HCC).By integrating radiomics w.th mol.cul.r anal.sis,the study presented a strategy for accuratel. predicting the expression of EZH2 from CT *** findings demonstrated a strong l.nk betw.en the radiomics model.EZH2 expression,and patient *** noninvasive approach provides val.abl. insights into the therapeutic management of HCC.

关键词： Hepatocel.ul.r carcinoma Computed tomography Radiomics Enhancer of zeste homol.gue 2 expression Non-invasive imaging