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Soil Gas Radon Measurement for Identifying Active Faults in Thua Thien Hue (Vietnam)

Journal of Geoscience and Environment Protection 2020年第7期8卷 44-64页

作者： Pham Tich Xuan Nguyen anh Duong vu Van Chinh Pham Thanh Dang Nguyen Xuan Qua Nguyen Van Pho Institute of Geological Sciences Vietnam Academy of Science and Technology Hanoi Vietnam Institute of Geophysics Vietnam Academy of Science and Technology Hanoi Vietnam

The solid-state nuclear track detectors have long been applied to assess the activity of tectonic faults. We measured the Radon (Rn) concentration in soil gas on 09 profiles with a total of 245 measurement points in Thua Thien Hue area (Vietnam). Measurement results show that the Rn concentration in soil gas ranges from ~10 Bq/m3 to 144,570 Bq/m3. There is a clear difference in the Rn concentration on the granite rock of Dai Loc complex compared to the remaining rocks. The calculated background value and anomaly threshold of Rn concentration on the granite rock of Dai Loc complex and on the remaining rocks are 33,488 Bq/m3, 82,839 Bq/m3 and 5313 Bq/m3, 24,850 Bq/m3 respectively. Spatial distribution of Rn concentration in soil gas reflects the existence of faults since Rn concentration increases at the points above or near fault lines. The level of expression of fault activity is assessed by radon activity index (KRn), which is calculated by the ratio of anomaly value to background value of Rn concentration. According to KRn, in Thua Thien Hue area, only the Dakrong-Hue fault shows a strong expression of activity with high and very high KRn (the maximum KRn = 27.21). The Truong Son, Huu Trach River, Ta Trach River and Bo River fault zones do not show clear activity with low and medium KRn. There is no Rn anomaly value recorded on the Rao Trang fault, demonstrating that it is likely to be inactive at present. The study results indicate that the Rn concentration in soil gas is a strong evidence of the existence of faults or tectonic fracture zones as the Rn concentration always increases at the points above or near the fault line.

关键词： Radon Active Fault Radon Activity Index Thua Thien Hue Vietnam

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Embryonic, genetic and clinical outcomes of fresh versus vitrified oocyte: A retrospective cohort study

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Asian pacific Journal of Reproduction 2023年第6期12卷 266-272页

作者： Phuong Dao Thi Son Dang Truong Thuan Nguyen Duc anh Pham Van anh Do Tuan Van Hanh Nguyen HP Fertility-hai Phong International Hospital of Obstetrics and Pediatrics Haiphong180000Vietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoi100000Vietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoi100000Vietnam

Objective:To compare embryonic development,ploidy status and clinical outcomes between fresh and frozen-thawed ***:This retrospective cohort study evaluated 83 fertilization cycles including both fresh and frozen oocytes from 79 patients at the HP Fertility Center of hai Phong International Hospital of Obstetrics and Pediatrics in *** patient underwent several ovarian stimulation cycles to accumulate a certain number of oocytes that would be *** the last oocyte retrieval,all patient’s oocytes including both frozen and fresh would be *** outcomes included the rates of oocyte survival,cleavage embryo,blastocyst,ploidy status,pregnancy,biochemical pregnancy and clinical ***:The oocyte survival rate after thawing was 96.5%.No statistically significant difference was found when comparing fresh and frozen oocytes regarding fertilization rate(78.1%vs.75.5%,P=0.461),usable cleavage embryo rate(86.9%vs.87.2%,P=0.916)but usable blastocyst rate was found higher statistically in the frozen oocyte group(44.4%vs.54.0%,P=0.049).The percentages of euploid,aneuploid and mosaic embryos between the fresh group and the vitrified group had no significant differences(33.8%vs.31.6%,P=0.682;51.0%vs.54.2%,P=0.569;15.2%vs.12.4%,P=0.787;respectively).The rates of pregnancy,biochemical pregnancy and clinical pregnancy had no statistical difference(68.8%vs.64.8%,P=0.764;12.5%vs.3.6%,P=0.258;37.5%vs.46.4%,P=0.565).17 Mature oocytes are the minimum to have at least one euploid ***:Oocyte vitrification does not affect embryonic,genetic and clinical *** number of mature oocytes should be considered for fertilization in some cases.

关键词： Clinical outcomes Embryonic development Genetic outcomes Human oocyte Oocyte accumulation Oocyte cryopreservation Ploidy status Vitrified oocyte

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Ilizarov胫骨横向骨搬移血管再生技术对下肢慢性缺血性疾病临床疗效的初步研究

Ilizarov胫骨横向骨搬移血管再生技术对下肢慢性缺血性疾病临床疗...

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作者：武黎黄英（vu Le Hoang anh）广西医科大学

学位级别：硕士

目的：初步探讨Ilizarov胫骨横向骨搬移血管再生技术对下肢慢性缺血性疾病的临床疗效。方法：回顾分析2012年4月至2012年7月在我院住院行Ilizarov胫骨横向骨搬移血管再生技术对下肢慢性缺血性疾病的4例病人,共有5个患肢;用Fontaine分... 详细信息

目的：初步探讨Ilizarov胫骨横向骨搬移血管再生技术对下肢慢性缺血性疾病的临床疗效。方法：回顾分析2012年4月至2012年7月在我院住院行Ilizarov胫骨横向骨搬移血管再生技术对下肢慢性缺血性疾病的4例病人,共有5个患肢;用Fontaine分期法进行分期诊断治疗;其中临床诊断为“下肢血栓闭塞性脉管炎,TAO" Fontaine IV期女性1例;“下肢动脉硬化闭塞症,ASO" Fontaine IV期男性3例;其中4例病人均发生足趾缺血性坏死,渗出伴有恶嗅,溃疡、疼痛;3例病人有动脉粥样硬化,无糖尿病、高血压、肝肾功能不全;1例病人有高血压病3级级高危组、小脑梗死。术前行患肢CT扫描+血管三维重建(Computed Tomography Artery,CTA)动脉粥样硬化狭窄1个患肢、显示胭动脉闭塞2个患肢、胫前动脉栓塞1个患肢和足背动脉及足底内外侧动脉栓塞1个患肢、4例病人的股深动脉和(或)者股浅动脉通畅、远端流出道不良。术中在病人的胫骨内侧嵴上开一小块胫骨窗2x12cm,术后第3天开始以每天缓慢横向外搬移1mm的游离胫骨窗,分4次完成,20天后停止。通过刺激骨膜和胫骨骨髓再生,以及刺激新鲜微小动脉再生,并形成新生毛细血管网。新生毛细血管网与原来的毛细血管网相连通,改善患肢缺血供。结果：5个患肢中4个患肢获得满意疗效。3例病人术后随访时间3-7个月,平均4.7个月,1例失访。下肢缺血症状明显改善,溃疡创面愈合,无并发症。1例病人术后2个月仍有患肢严重血供不良,病人放弃治疗要求下肢截肢术。结论：Ilizarov骨搬移血管再生技术对下肢慢性缺血性疾病有较好的临床疗效,能促进骨膜、骨髓再生和外周新生血管网形成,改善患肢局部血供,以及促进创面愈合。本手术方法简便,易操作;创面小,术后病情改善快,有利于避免截肢,减轻患者痛苦,提高患者的生活质量;手术费药物用低;病情不易复发。

关键词： Ilizarov 骨搬移血管再生技术血栓闭塞性脉管炎动脉硬化闭塞症

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越中美三角关系研究

越中美三角关系研究

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作者：武氏兰英（vu THI LAN anh）上海外国语大学

学位级别：硕士

本文主要去研究越、中、美三国之间的互动关系。在越南与中国、美国、俄罗斯、印度、日本等重要国家的关系中,最重要的是越中关系和越美关系。作为社会主义国家,越中两国之间的关系从关系正常化以来发展较为稳定,并没有恢复像“朋友加... 详细信息

本文主要去研究越、中、美三国之间的互动关系。在越南与中国、美国、俄罗斯、印度、日本等重要国家的关系中,最重要的是越中关系和越美关系。作为社会主义国家,越中两国之间的关系从关系正常化以来发展较为稳定,并没有恢复像“朋友加兄弟”的时代。相比之下,越美关系自建立外交关系以来获得了全面而快速地发展。两国在过去的恩怨都已被看成历史的尘埃。实际上,越中美三角关系是不太对称的“三角”。因为,越南主要是地区性大国,美国是全球性大国,而中国是从地区性大国向全球性大国转换的国家。但是,如果越南与中国或美国联合起来,会对第三国产生威胁,是很大的国家安全方面的威胁。因此,在越中美三角关系中,越南扮演着很重要的作用。本文的目的是要探索在近代特别是1975年以来,越中美三国在东南亚地区的互动规律。首先本人假定越中美三国之间存在着某种规律,然后再去研究到底是不是符合这种规律。三个规律是三个变量因素。第一个规律就是“均势”,第二个规律是意识形态,意识形态之间的斗争是影响三国关系的主要因素,是重要考量;第三个规律是区域组织的因素,或者“区域一体化”。全文分成六个部分,包括导论部分及五章。本文第一章主要是研究框架通过地区均势、意识形态因素与区域一体化理论。第二章主要概述了上个世纪七十年代至九十年代初的越南、中国和美国三角关系。第三章主要是九十年代前期的越中美关系。第四章主要分析了进入新世纪越中美三角关系如何转变。最后一章是分析影响越中美三国关系的其他因素,加上越、中、美三角关系的展望。

关键词：越南、中国、美国三角关系研究

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Application of Word Embedding to Drug Repositioning

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Journal of Biomedical Science and Engineering 2016年第1期9卷 7-16页

作者： Duc Luu Ngo Naoki Yamamoto vu anh Tran Ngoc Giang Nguyen Dau Phan Favorisen Rosyking Lumbanraja Mamoru Kubo Kenji Satou Graduate School of Natural Science and Technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

As a key technology of rapid and low-cost drug development, drug repositioning is getting popular. In this study, a text mining approach to the discovery of unknown drug-disease relation was tested. Using a word embedding algorithm, senses of over 1.7 million words were well represented in sufficiently short feature vectors. Through various analysis including clustering and classification, feasibility of our approach was tested. Finally, our trained classification model achieved 87.6% accuracy in the prediction of drug-disease relation in cancer treatment and succeeded in discovering novel drug-disease relations that were actually reported in recent studies.

关键词： Distributed Representation of Word Sense Discovery of Drug-Disease Relation Word Analogy

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Predicting residue contacts for protein-protein interactions by integration of multiple information

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Journal of Biomedical Science and Engineering 2014年第1期7卷 28-37页

作者： Tu Kien T. Le Osamu Hirose vu anh Tran Thammakorn Saethang Lan anh T. Nguyen Xuan Tho Dang Duc Luu Ngo Mamoru Kubo Yoichi Yamada Kenji Satou Graduate School of Natural Science and Technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

Detailed knowledge of interfacial region between interacting proteins is not only helpful in annotating function for proteins, but also very important for structure-based drug design and disease treatment. However, this is one of the most difficult tasks and current methods are constrained by some factors. In this study, we developed a new method to predict residue-residue contacts of two interacting protein domains by integrating information about evolutionary couplings andamino acid pairwise contact potentials, as well as domain-domain interaction interfaces. The experimental results showed that our proposed method outperformed the previous method with the same datasets. Moreover, the method promises an improvement in the source of template-based protein docking.

关键词： Residue-Residue Contacts Domain-Domain Interactions Protein-Protein Interactions Domain Interfaces Residue Co-Evolution Contact Potentials

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Formulation Optimization Utilizing D-Optimal Experimental Design of Oral Capsules Containing Enteric-Coated Pellets of Lansoprazole and<i>in vivo </i>Bioequivalence

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Pharmacology & Pharmacy 2017年第5期8卷 153-171页

作者： anh Quang Luong Thang Ngoc vu Dang Hoa Nguyen Sultan M. Alshahrani John Mark Christensen Chien Ngoc Nguyen Department of Pharmacy National Institute of Burns Hanoi Vietnam Research and Training Center for Pharmacy Military Medical University Hanoi Vietnam Military Institute of Pharmaceutical Analysis and Research Hanoi Vietnam Department of Pharmaceutics Hanoi University of Pharmacy Hanoi Vietnam Department of Pharmaceutical Sciences College of Pharmacy Oregon State University Corvallis Oregon USA National Institute of Pharmaceutical Technology Hanoi University of Pharmacy Hanoi Vietnam

An optimized formulation of capsules containing Lansoprazole enteric-coated pellets using D-Optimal design with a polynomial statistical model were prepared by using Eudragit?L100 as an enteric coated polymer to provide resistance to simulated gastric acid dissolution in buffer media. D-Optimal experimental design was used to determine the optimal level for three coating layers that were applied to formulate the enteric-coated pellets including a drug loading layer, a sub-coating, and an outer enteric coating. Dissolution studies were performed on the prepared Lansoprazole capsules. Less than 5 percent of Lansoprazole was released in 60 minutes in an acidic dissolution medium (pH 1.2) and greater than 90 percent of active ingredient was released in the next 60 minutes in a buffer dissolution medium (pH 6.8). The Lansoprazole capsules were stable with no observable change in physico-chemical properties in accelerated and normal storage conditions for 6 and 18 months, respectively. The pharmacokinetic parameters Cmax, Tmax, AUC0-t, and AUC0-∞ were determined after administration of the D-Optimal design optimized capsules of LPZ to healthy beagle dogs and were statistically compared to Gastevin? capsules as a reference (KRKA, Slovenia) using the non-compartmental method with the aid of WinNonlin 5.2 software. The analysis of variance showed that the two formulations did not demonstrate bioequivalence using a 90% confidence interval range (80% - 120%) of Cmax, AUC0-t, and AUC0-∞. No significant difference in Tmax was found at the 0.95 significance level using the Wilcoxon signed-rank test. D-Optimal Experimental Design provided definitive direction for an optimal formulation of capsules containing enteric-coated pellets of lansoprazole loaded within the coating of pellets that provided similar bioequivalence to Gastevin.

关键词： Lansoprazole D-Optimal Pellets Enteric-Coating Pharmacokinetic Parameters

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越南盾汇率与股票价格联动关系研究 ——基于VN-index的实证分析

越南盾汇率与股票价格联动关系研究 —...

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作者：阮海英（Nguyen hai anh）湖北大学

学位级别：硕士

股票市场是发达经济体中的重要组成部分,市场的起伏以及潜在的风险和丰厚的利润一直是经济学者以及股票市场投资者感兴趣的话题。作为影响股票市场因素之一的汇率同样会在金融市场中起到至关重要的作用,汇率与股票价格之间存在着的联动... 详细信息

股票市场是发达经济体中的重要组成部分,市场的起伏以及潜在的风险和丰厚的利润一直是经济学者以及股票市场投资者感兴趣的话题。作为影响股票市场因素之一的汇率同样会在金融市场中起到至关重要的作用,汇率与股票价格之间存在着的联动效应是否协调,关系到整个金融市场的平稳运行,稍有不慎可能引发金融危机,影响国民经济的健康发展。国外很多学者对两者的联动关系进行了研究,但是大部分研究都针对相对发达的经济体或者国家的情况。越南的股票市场相对国外发达国家发展较晚,相关研究大部分运用传统的回归模型研究它们的联系,缺少对内生变量的相互影响的解释。在本文中,我们使用向量自回归模型（VAR）以及其他一些附加分析,如ADF单位根检验、Johansen协整检验、Granger因果分析、方差分解以探讨汇率与股价之间的关系。研究的数据是从2011年1月到2020年12月越南盾兑美元的名义汇率和VN股票指数的数据。通过理论与实证分析,本文得出以下结论:存在从越南盾兑美元汇率到VN指数的因果关系,但不存在VN指数到越南盾兑美元汇率的因果关系。这说明在汇率和股价之间只有单向传导关系。通过Johansen协整关系检验,我们发现越南盾兑美元汇率与VN指数之间没有长期的均衡关系,其原因主要是越南的股票市场规模很小,没有足够的力量影响整个经济;其次,由于历史特征,上市公司大多是国有公司,因此国有资本的占比仍然很高,在市场上买卖股票的数量还不足以影响包括汇率市场在内的整个经济。最后本文在实证分析的基础上,结合越南的实际情况分析了股票市场和外汇市场中存在的问题,并针对相关的问题提出了完善股票市场和汇率市场的建议。

关键词：越南盾汇率股票价格联动性 VN指数

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Assessing Satellite-Based Precipitation Products to Create Flood Forecasting in the Da River Basin, Vietnam

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Journal of Geoscience and Environment Protection 2019年第11期7卷 113-123页

作者： Le Viet Son Luong Ngoc Chung Bui Tuan hai Sai Hong anh Nguyen Duy Quang Division for Water Resources Planning for the North Region Institute of Water Resources Planning Hanoi Vietnam Board of directors Institute of Water Resources Planning Hanoi Vietnam Department of Agro-Environmental Sciences Graduate School of Bioresource and Bioenvironmental Sciences Kyushu University Fukuoka Japan

The Da River Basin is an international basin where available access to hydrological data is limited;it has a total basin area of 52,900 km2, about 50% of the area in which it is located, Vietnam. The Da River is the primary source of water for agriculture in 25 provinces and cities, and the primary source of drinking water for more than 30 million people in both urban and rural areas. It has huge economic and historical value. However, flood forecasting for the Da River basin has not been adequately addressed yet because of the challenge of the inconsistency, scarcity, poor spatial representation, as well as difficult access and incompleteness of the availability of ground observed rainfall data. In this research, the IFAS model has been utilized to assess the benefits of using satellite-based precipitation products to create flood forecasting for the whole research area. The results showed that the Integrated Flood Analysis System (IFAS) model was able to integrate the satellite-based precipitation products for simulating the flood event in the Da River basin. Also, the 3B42RT algorithm showed a definite improvement in reproducing the flood peak and low flow very well in the research area. These results could be used to enhance the effectiveness of flood management strategy in the basin.

关键词： IFAS Flood Flow 3B42RT and GSMaP Algorithm

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化学絮凝结合真空预压处理的渤海湾海洋疏浚泥固结特性

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大连理工大学学报 2022年第6期62卷 626-632页

作者：陈国公武亚军许嘉乐李运红王攀秦荣荣 LE Thanh hai vu Quoc vuong 上海大学土木工程系上海200444 中国冶金地质总局青岛地质勘查院山东青岛266109 越南胡志明市国立大学资源与环境研究院胡志明市740500越南越南水利大学土木工程学院河内116301越南

为了改善渤海湾海洋疏浚泥渗透性差和排水固结时间长的不足,引入化学絮凝结合真空预压的地基处理方法.首先分析了山东东营地区疏浚泥的矿物成分与物理性质,然后采用两种不同的絮凝剂进行了沉降柱试验与真空预压模型试验.结果表明:絮凝剂... 详细信息

为了改善渤海湾海洋疏浚泥渗透性差和排水固结时间长的不足,引入化学絮凝结合真空预压的地基处理方法.首先分析了山东东营地区疏浚泥的矿物成分与物理性质,然后采用两种不同的絮凝剂进行了沉降柱试验与真空预压模型试验.结果表明:絮凝剂APAM添加量越大,混液面沉降速度越快,在添加量为15%时速度最快,约5 min内沉降基本稳定;絮凝剂CaO添加量越大,混液面沉降速度越慢,当添加量越过某一值(10%)时,最终混液面基本保持不变;真空预压排水速率并非絮凝剂添加量越大越快,絮凝剂CaO添加量为0.6%时速率最快,絮凝剂APAM添加量为15%时速率最快.研究成果对于东营疏浚泥地基处理工程实践具有一定的指导意义.

关键词：渤海湾疏浚泥絮凝真空固结

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