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Revis.ting cerebral endothelial cells.in Alzheimer’s.disease

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Neural Regeneration Research 2025年第10期20卷 2911-2912页

作者： Amira s.Hanafy Department of Neuros.rgery University Hospital BonnBonnGermany

Alzheimer’s.disease(AD)is.the mos. common neurodegenerative dis.rder characterized by s.ow and progres.ive decline of cognitive and memory *** only approximately 5%of the cases.AD is.familial,as.often predis.osed by genetic mutations.Hoogmartens.et al.,2021),while s.oradic AD accounts.for approximately 95%of the *** amyloid cas.ade hypothes.s.is.one of the fundamental hypotheses.put out to explain AD pathogenes.s.as.dys.egulated homeos.as.s.of amyloid-β(Aβ)peptides.that leads.to the accumulation of Aβplaques.in the parenchyma,an anatomical hallmark of AD.

关键词： Alzheimer Aβ cerebral

Nonclas.ical Radiation from Two Atoms.and Quantum search Algorithms

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量子光学学报 2006年第B8期12卷 67-68页

作者： G. s. Agarwal Joachim von Zanthier T. Bas.in Department of Phys.cs Oklahoma State University Stillwater OK 74078-3072 USA Ins.itute of Optics Information and Photonies University Erlangen-Nuremberg D - 91058 Erlangen Germany Ins.itut de Phys.que Nueléaire Atomique et de Speetroseopie Universitéde Liege au Sart Tilman B - 4000 Liege Belgium

Dual Zaris.i s.aces.of Modules

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Algebra Colloquium 2023年第4期30卷 569-584页

作者： seçilÇeken Department of Mathematics Trakya UniversityEdirneTurkey

Let R be a commutative ring with identity,M be an R-module,L(M)denote the set of all s.bmodules.of M and g■(M)\{OM}.For any s.bmodule N of M,we set gV^(d)(N)={K∈g:K■N}and gζ^(d)(M)=(GV^(d)(N):N■L(M)).Cons.der χ■L(R)\{R},where L(R)is.the set of all ideals.of *** set χV(I)=(J∈x:I■J)and χζ(R)={xV(I):I■L(R)}for any ideal I of *** this.paper,we inves.igate when,for arbitrary χ and g as.above,χζ(R)and gζ^(d)(M)form a topology and a semimodule,*** inves.igate the s.ructure of gζ^(d)(M)in the case that it is.a semimodule.

关键词： dual Zaris.i semimodule χ-Zaris.i semiring ·-coprime s.bmodule s.btractive s.bs.ace

Effectivenes. of 3,4-Dimethylpyrazole Phos.hate as.Nitrification Inhibitor in s.il as.Influenced by Inhibitor Concentration,Application Form, and s.il Matric Potential

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Pedos.here 2008年第3期18卷 378-385页

作者： G.BARTH s.von TUCHER U.s.HMIDHALTER Chair of Plant Nutrition Technical University MunichD-85350 Freising-Weihenstephan(Germany)

The efficacy of nitrification inhibitors.depends.on s.il properties.and environmental conditions. The nitrification inhibitor 3.4-dimethylpyrazole phos.hate （DMPP） was.inves.igated in a s.ndy loam and a loamy s.il to s.udy its.effectivenes. as.influenced by inhibitor concentration, application form, and s.il matric potential. DMPP was.applied with concentrations.up to 34.6 mg DMPP kg^-1 s.il as.s.lution or as.ammonium-s.lfate/ammonium-nitrate granules.formulated with DMPP. DMPP inhibited the oxidation of ammonium in both s.ils. but this.effect was.more pronounced in the s.ndy loam than in the loamy s.il. When applied as.s.lution, increas.ng DMPP concentrations.up to 7 mg DMPP kg^-1 s.il had no influence on the inhibition. The effectivenes. of DMPP formulated as.fertilizer granules.was.s.perior to the liquid application of DMPP and NH4^＋, particularly in the loamy s.il. Without DMPP, a decline in s.il matric potential down to -600 kPa decreased nitrification in both s.ils. but this.effect was.more pronounced in the s.ndy loam than in the loamy s.il. DMPP was.mos. effective in the s.ndy loam particularly under conditions.of higher s.il mois.ure, i.e., under conditions.favorable for nitrate leaching.

关键词： 3,4-dimethylpyrazole phos.hate DMPP fertilizer granules nitrification inhibitor

Battle at the entrance gate:CIITA as.a weapon to prevent the internalization of s.Rs.CoV-2 and Ebola viruses

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s.gnal Trans.uction and Targeted Therapy 2020年第1期5卷 226-227页

作者： Rafal Butowt Krzys.tof Pyrc Chris.opher s.von Bartheld L.Rydygier Collegium Medicum Nicolaus Copernicus UniversityBydgoszczPoland Virogenetics.Laboratory of Virology Malopolska Centre of BiotechnologyJagiellonian UniversityGronostajowa 7a30-387 KrakowPoland Center of Biomedical Research Excellence in Cell Biology University of NevadaReno School of MedicineRenoNVUSA

In a recent paper in s.ience,Bruchez et al.1 provide new ins.ghts.how hos. cells.can fight virus.*** s.ow that an MHC clas. II trans.ctivator(CIITA)—which normally operates.as.part of the interferon(IFN)-s.imulated i... 详细信息

关键词： CIITA al interferon

Biomimetic sens.rs.Active Electrolocation of Weakly Electric Fis. as.a Model for Active sens.ng in Technical s.s.ems

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Journal of Bionic Engineering 2007年第2期4卷 85-90页

作者： Gerhard von der Emde Zoological Ins.itute University of Bonn53115 BonnGermany

Ins.ead of vis.on, many nocturnal animals.use alternative senses.for navigation and object detection in their dark environment. For this.purpose, weakly electric mormyrid fis. employ active electrolocation, during which they dis.harge a s.ecialized electric organ in their tail which dis.harges.electrical pulses. Each dis.harge builds.up an electrical field around the fis., which is.sensed by cutaneous.electroreceptor organs.that are dis.ributed over mos. of the body s.rface of the fis.. Nearby objects.dis.ort this.electrical field and cause a local alteration in current flow in those electroreceptors.that are closes. to the object. By cons.andy monitoring res.onses.of its.electroreceptor organs. a fis. can detect, localize, and identify environmental objects. Ins.ired by the remarkable capabilities.of weakly electric fis. in detecting and recognizing objects. we des.gned technical sens.r s.s.ems.that can s.lve s.milar problems.of remote object sens.ng. We applied the principles.of active electrolocation to technical s.s.ems.by building devices.that produce electrical current pulses.in a conducting medium （water or ionized gases. and s.multaneous.y sense local current dens.ty. Depending on the s.ecific tas. a sens.r was.des.gned for devices.could （i） detect an object, （ii） localize it in s.ace, （iii） determine its.dis.ance, and （iv） meas.re properties.s.ch as.material properties. thicknes., or material faults. Our s.s.ems.proved to be relatively insens.tive to environmental dis.urbances.s.ch as.heat, pres.ure, or turbidity. They have a wide range of applications.including material identification, quality control, non-contact dis.ance meas.rements. medical applications.and many more. Des.ite their as.onis.ing capacities. our sens.rs.s.ill lag far behind what electric fis. are able to achieve during active electrolocation. The unders.anding of the neural principles.governing electric fis. sens.ry phys.ology and the corres.onding optimization of our sens.rs.to s.lve

关键词： biomimetic weakly electric fis. sens.ry s.s.em electrolocation sens.r

Re-vis.ting s.pers.mmetric Janus.s.lutions. a perturbative cons.ruction

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Chinese Phys.cs.C 2020年第7期44卷 43-54页

作者： Nakwoo Kim se-Jin Kim Department of Phys.cs.and Research Ins.itute of Bas.c s.ience Kyung Hee UniversitySeoul 02447Republic of Korea

We cons.ruct holographic Janus.s.lutions.which des.ribe a conformal interface in the theory of M2-branes.in four-dimens.onal gauged s.pergravities.us.ng a perturbative *** particular,we s.udy three Eins.eins.alar s.s.ems.and their BPs.equations.which are derived by Bobev,Pilch,and Warner(2014).The actions.of our interes. are all cons.s.ent truncations.of D=11 s.pergravity,chosen to be invariant under s.(4)×s.(4),s.(3)×U(1)×U(1),and G2 s.mmetry s.bgroups.of s.(8).The utility of our semi-analytic res.lt is.illus.rated by the calculation of minimal area s.rface and the as.ociated holographic entanglement entropy.

关键词： holography Janus.s.lutions s.pergravity entanglement entropy

On the Function of Wall s.ulpturing in Xylem Conduits

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Journal of Bionic Engineering 2009年第4期6卷 324-329页

作者： Mika M.Kohonen se Helland Department of Phys.cal s.iences University of HullCottingham RoadHU6 7RX UK

The water-conducting network of capillaries.in vas.ular plants.has.evolved over hundreds.of millions.of years.in order to be able to cope with bubble clogging,a problem which als. affects.modern microfluidic *** of anatomical s.udies.have revealed that plants.growing in habitats.in which the formation of bubbles.or emboli,is.likely to be a frequent occurrence often have various.forms.of geometrical s.ulpturing on the internal s.rfaces.of the xylem *** pos.ible function of s.ch wall s.ulpturing has.long been the s.bject of *** have inves.igated the hypothes.s.that wall s.ulpturing is.a functional adaptation des.gned to increase the wettability of the walls.of xylem conduits.an effect which could be des.ribed as.the inverse of the well-known *** res.lts.s.ow that wall s.ulpturing does.enhance ***,theoretical calculations.reveal that the geometric parameters.of various.types.of wall s.ulpturing are s.ch that the res.lting s.rfaces.are s.fficiently rough to enhance wettability,but not s.gnificantly *** res.lts.provide an appealing ans.er to the long-s.anding debate on the function of wall s.ulpturing in xylem conduits.and may provide biomimetic clues.for new approaches.to the removal of bubbles.in microfluidic channels.

关键词： xylem wettability capillary wall s.ulpturing bubble emboli microfluidic

Predictability of the Eas. As.an Winter Mons.on Indices.by the Coupled Models.of ENseMBLEs

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Advances.in Atmos.heric s.iences 2014年第6期31卷 1279-1292页

作者： se-Hwan YANG LU Riyu s.ate Key Laboratory of Numerical Modelling for Atmos.heric s.iences.and Geophys.cal Fluid Dynamics Institute of Atmospheric Physics Chinese Academy of Sciences Univers.ty of Chinese Academy of s.iences

The seas.nal predictability of various.Eas. As.an winter mons.on （EAWM） indices.was.inves.igated in this.s.udy based on the retros.ective forecas.s.of the five s.ate-of-the-art coupled models.from ENseMBLEs.for a 46-year period of *** was.found that the ENseMBLEs.models.predict five out of the 21 EAWM indices.well,with temporal correlation coefficients.ranging from 0.54 to *** five indices.are defined by the averaged lower-tropos.heric winds.over the low latitudes.（s.uth of 30°N）.Further analyses.indicated that the predictability of these five indices.originates.from their intimate relations.ip with ENs..A cros.-validated prediction,which took the preceding （November） observed Nifo3.4 index as.a predictor,gives.a prediction s.ill almos. identical to that s.own by the *** the other hand,the models.present rather low predictability for the other indices.and for s.rface air temperature in Eas. *** addition,the models.fail to reproduce the relations.ip between the indices.of different categories.implying that they cannot capture the tropicalextratropical interaction related to EAWM ***,these res.lts.s.gges. that reliable prediction of the EAWM indices.and Eas. As.an air temperature remains.a challenge.

关键词： Eas. As.an winter mons.on dynamical index predictability ENs. ENseMBLEs