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Risk Factors for COVID-19 Related Death during the First Three Waves of the Pandemic in an Epidemic Treatment Center at Dakar, Senegal

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Advances in Infectious Diseases 2023年第2期13卷 117-131页

作者： Moustapha Diop Papa Samba Ba viviane Marie Pierre Cisse Ndèye Aissatou Lakhe Betty Fall Moustapha Lo Ndong Essomba Bruce Wembulua Fatimata Wone Becaye Fall Khardiata Diallo-Mbaye Daye Ka Louise Fortes Ousmane Faye Ndongo Dia Khalifa Ababacar Wade Abdou Rajack Ndiaye Amadou Alpha Sall Moussa Seydi Mame Thierno Dieng Epidemic Treatment Center Dakar Principal Hospital Dakar Senegal Infectious and Tropical Diseases Department FANN Teaching Hospital Dakar Senegal Psychiatry Department Dakar Principal Hospital Dakar Senegal Internal Medicine Department Deido District Hospital Douala Cameroon Dalal Jamm Hospital Dakar Senegal Federation of Laboratories Dakar Principal Hospital Dakar Senegal Pasteur Institute of Dakar Dakar Senegal Anesthesia-Resuscitation Department Dakar Principal Hospital Dakar Senegal Dakar Principal Hospital Dakar Senegal

Introduction-Objective: COVID-19 is a highly transmissible but often mild viral infection. However, some patients can present severe COVID-19 and subsequently die. The aim of the present study was to assess the risk factors for COVID-19 related death during the first three waves of the disease at the Epidemic Treatment Center (ETC) of Dakar Principal Hospital (DPH). Method: We conducted a descriptive and analytical perspective survival study from April 4, 2020 to September 25, 2021, including adult patients with COVID-19, hospitalized at the ETC of DPH. Log Rank test and multivariate Cox model were performed to identify risk factors for death. Results: We included 556 COVID-19 patients with mean age of 57 ± 17 years and a male-to-female ratio of 1.26. The number of deaths during one month of follow-up was 41, representing a cumulative risk of 7.4%. The log Rank test showed that being from the third wave (p = 0.0056), advanced age (p = 0.00098), presence of at least one comorbidity (p = 0.034), High blood pressure (p = 0.024), d-dimer level ≥ 1000 IU/L (p Conclusion: Our study showed that elderly and third-wave of COVID-19 patients were more at risk to die. Knowledge of risk factors for COVID-19 related death could improve the prognosis of these patients.

关键词： COVID-19 Waves Death Risk Factors Dakar

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A Study of Laser Effectiveness in Injured Tissues Regeneration

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Journal of Biosciences and Medicines 2021年第3期9卷 55-63页

作者： Marcus Vinicius de Mello Pinto Aline Ronis Sampaio Miriam viviane Baron Carolina Macedo Alves Moreira Carolina Gonçalves Pinheiro Michele Paula dos Santos Andres Felipe Mantilla Santamaria Cristine Brandenburg Nathália Ken Pereira Iketani Mara Alessandra Porto dos Reis Oliveira Alexandre Sancho Felice Picariello Esteban Fortuny Juliano Tibola Nilton Petrone Vilardi Junior Celulare Institute Petrópolis Rio de Janeiro Brazil School of Medicine Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Brazil Dr. Daniel Thomaz Clinic Uberlandia Minas Gerais Brazil Faculty of Medicine of ABC (FMABC) Santo André Brazil Vale do Salgado Faculty (FVS) Ceará Brazil School of Medicine Industrial University of Santander (UIS) Bucaramanga Colombia Federal University of Ceará (UFC) Fortaleza Brazil Hospital Beneficiente Portuguesa of Belém Pará Brazil Clínica Instituto de Cirurgia Plástica Vênus Barreiras Bahia Brazil Unigranrio Rio de Janeiro Brazil da Universita Federico II di Napoli Italia e Pesquisador do Internacional Research Group Rio Grande do Norte Brazil Universidad Finis Terrae Santiago Chile UDESC Florianopolis SC Brazil Fluminense Football Club Rio de Janeiro RJ Brazil

This study aimed to understand the use of low level laser in the regeneration of injured tissues. Also to design our own opinion on the subject, as chemists. Laser is nothing more than a light with very special characteristics that grant it therapeutic properties. We can observe the existence of three different types of laser, being one of them the therapeutic laser, which is used in substitution for medications or along with them. Another type of laser is the surgical one and, in addition to these, there is a diagnostic type. A great advantage is that, instead of taking the medicine, the patient’s own body can be activated by the laser to produce certain substances that can often replace the drugs. This is a literature review emphasizing the use of low level laser. Thus, the reflections from this study can contribute to the amplification of the production of knowledge that aims at the resignification of the use of laser in therapy. Greater attention was given to two types of laser radiation: He-Ne and As-Ga, both presenting a high therapeutic potential in superficial and deep injures. However, the He-Ne laser excels in superficial lesions, whereas the As-Ga laser does so in deep injures, such as articular, muscular, etc.

关键词： Laser Injury Regeneration

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Epidemiological, Clinical and Outcome Aspects of Care-Related Tetanus in Dakar, Senegal

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Advances in Infectious Diseases 2022年第2期12卷 230-240页

作者： viviane Marie Pierre Cisse Ndèye Fatou Ngom Gueye Louise Fortes Imelda Mickelina Thoo Aminata Massaly Khardiata Diallo Mbaye Daye Ka Ndèye Aissatou Lakhe Assane Diouf Ndèye Maguette Fall Daouda Thioub Aboubakry Sidikh Badiane Latyr Junior Diouf Alassane Sarr Sylvie Audrey Diop Cheikh Tidiane Ndour Masserigne Soumaré Moussa Seydi Infectious and Tropical Diseases Department Fann Teaching University Hospital Dakar Senegal Department of Community Health Alioune Diop University Bambey Senegal Department of Health Thies University Thies Senegal

Introduction: Tetanus portals of entry are numerous. Amongst these, the carerelated portals of entry are rarely reported. The aim of the study was to describe the epidemiological, clinical and outcome aspects and identify the factors associated with death from care-related tetanus. Patients and Methods: This is a retrospective study of descriptive and analytical purposes. Data were collected from the medical records of patients admitted to the Infectious and Tropical Diseases Department of the National University Hospital Center (CHNU) of Fann in Dakar for care-related tetanus during the period ranging from 1 January 2009 to 31 December 2016. Care-related tetanus was defined as any case of tetanus occurring after a surgical procedure, including circumcisions performed even outside a health facility. Results: In eight years, 50 cases of care-related tetanus were recorded. Care-related tetanus accounted for 6.7% of hospitalized tetanus cases. The mean age of patients was 21 ± 22 years, with a male predominance (sex ratio: 6.14). The procedure had been performed in most cases, either in a health facility in 22 patients (44%) or at home in 16 patients (32%), and occurred after circumcision. In 62% of cases the portal of entry was urological, followed by orthopedic surgery (14%) and visceral surgery (10%). The procedures performed were dominated by circumcision (31 cases), limb amputation (3 cases) and inguinal hernia repair (2 cases). Tetanus was immediately generalized on admission in all patients. Eighty-four percent (84%) of patients were admitted with Mollaret stage II. Cardiovascular (11 cases), infectious (10 cases) and respiratory (9 cases) complications were the most frequent. The hospital case fatality rate was 24%. Factors associated with death were female gender (p = 0.03), age between 15 - 60 years (p = 0.02), incubation time Conclusion: Care-related tetanus remains a concern in poor income countries, particularly in Senegal. The drop of these cases will req

关键词： Tetanus Care Surgery Dakar Senegal

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Cementitious Composites Containing Multifunctional Sugarcane Fibres

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Journal of Building Material Science 2019年第2期1卷 1-8页

作者： viviane VSGuilarduci Patricia Benedini Martelli Honória de Fátima Gorgulho Pablo Resende Oliveira Tulio Hallak Panzera Núcleo de Ambiente Saúde e SegurançaIF Sudeste MGSão João del-ReiBrazil Department of Natural Sciences–DCNAT Federal University of São João Del-Rei-UFSJBrazil Centre for Innovation and Technology in Composite Materials–CITeC Department of Mechanical EngineeringFederal University of São João Del-Rei-UFSJBrazil

This work investigates the reuse of natural(SCB)and minopropyltriethoxysilanemodifed(MSCB)sugarcane bagasse fbres in cementitious *** bagasse fbres are pre-used in the treatment of motor oil contaminated effluents.A full factorial design is used to identify the effects of fbre type(SCB and MSCB),fbre length(0.6 and 1.2 mm),fbre amount(1 and 2 wt%)and fbre condition(before and after oil filtration)on apparent density,water absorption,apparent porosity,ultra-pulse velocity,dynamic modulus,flexural strength and *** fibres lead to increased apparent density compared to MSCB fibre reinforced *** fibres contribute to reduce composite porosity,leading to higher mechanical *** smaller area of MSCB fibres promotes a larger amount of cementitious phase per unit volume,thus increasing the strength of the *** sugarcane fbres(1.2 mm)have a larger surface area,leading to a higher fibre concentration per unit volume,which increases water *** amount of fibre has no significant effect on mechanical and physical *** made with 2 wt%0.6 mm long MSCB fibres achieve promising results for non-structural civil engineering applications.

关键词： Sugarcane bagasse Treatment of effluents Chemical treatment Cementitious composites Mechanical properties Non-destructive test Design of experiment

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小剂量瑞芬太尼对全麻苏醒拔管期不良反应的作用

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麻醉与镇痛 2010年第6期6卷 55-59页

作者： Marie T. Aouad Achir A. Al-Alami viviane G. Nasr Fouad G. Souki Reine A. Zbeidy Sahar M. Siddik-Sayyid 韩柳(译) 李成辉(校) Department of Anesthesiology American University of Beirut Medical Center Beirut Lebanon 不详

背景瑞芬太尼可以减轻全麻苏醒期时的咳嗽、躁动和血流动力学变化等不良反应。方法在一项前瞻性、随机、双盲临床试验中，60例接受鼻部手术的成人患者采用以瑞芬太尼为基础的麻醉方案。在苏醒期，瑞芬太尼组患者将瑞芬太尼用量减至维持... 详细信息

背景瑞芬太尼可以减轻全麻苏醒期时的咳嗽、躁动和血流动力学变化等不良反应。方法在一项前瞻性、随机、双盲临床试验中，60例接受鼻部手术的成人患者采用以瑞芬太尼为基础的麻醉方案。在苏醒期，瑞芬太尼组患者将瑞芬太尼用量减至维持量的1／10，而对照组患者则停止使用。结果两组患者的苏醒时间和气管拔管时间无明显区别。与对照组相比，瑞芬太尼组在苏醒期（输注速率：0．014±0．011μg·kg·min^-1）的咳嗽发生率（40％vs80％，P=0．002）和严重程度均明显减轻，不自主运动发生率降低（3．3％vs30％，P=0．006），心率较慢。结论在苏醒期使用小剂量瑞芬太尼不会延长苏醒时间，且降低气管插管所致咳嗽的发生率和严重程度。

关键词：全麻苏醒期瑞芬太尼不良反应小剂量苏醒拔管期血流动力学变化成人患者双盲临床试验

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2020东京奥运会官方艺术海报

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中外文摘 2020年第4期 I0002-I0003页

作者： Shoko Kanazawa Dajjiro Ohara Shinro Ohtake Asao Tokolo Taku Satoh Tomoko Konoike Theseus Chan Philippe Weisbecker viviane Sassen Chris Ofili Goo Choki Par Koji Kakinuma Hirohiko Araki Tomoyuki Shinki 不详

东京奥运会组委会公布了一组艺术海报,参与创作的艺术家包括日本天才书法家金泽翔子,一线女艺术家蜷川实花,漫画家浦泽直树、荒木飞吕彦,荷兰新锐女摄影师薇薇安娜·萨森等。

关键词：东京奥运会女艺术家奥运会组委会海报女摄影师蜷川实花书法家

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Hospital Admissions and Mortality in Patients with Rheumatic Heart Disease in Brazil:An Analysis from 2008 to 2018

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Advances in Infectious Diseases（传染病进展） 2020年第4期

作者： Mariana Silva Nunes Gustavo Tedde-Filho João carlos Geber-Júnior Willian Darwin Júnior viviane Uliane Peterle Ana Paula Monteiro Gomides

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Opportunistic Infections in Late Kidney Transplantation with Death Outcome: Case Report

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Open Journal of Nephrology 2021年第2期11卷 171-182页

作者： Miriam viviane Baron Carina Marangoni Michele Paula dos Santos Célia Regina Martins Korzenieski Vitória Pereira Itaquy Tais Michele Werle Gabriela Di Lorenzo Garcia Scherer Joice Nedel Ott Marcus Vinicius de Mello Pinto Janine Koepp Carolina Gonçalves Pinheiro Nathália Ken Pereira Iketani Cristine Brandenburg Aline Ronis Sampaio Alexandre Sancho Danielle de Mello Florentino Bartira Ercília Pinheiro da Costa Postgraduate Program in Medicine and Health Sciences of the Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Brazil Coordination for the Improvement of Higher Education Personnel Brazilia Brazil School of Medicine of the Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Brazil Schoolof Health and Life Sciences of the Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Brazil CelulareInstitute Rio de Janeiro Brazil University of Santa Cruz do Sul (UNISC) Santa Cruz do Sul Brazil Postgraduate Program in Health Sciences of the Faculty of Medicine of ABC (FMABC) S&atilde o Paulo Brazil Hospital Beneficiente Portuguesa of Belém Pará Brazil Dom José Institute of Education and Culture/University of Vale do Acaraú (IDJ/UVA) Ceará Brazil Unigranrio University Rio de Janeiro Brazil Uniredentor University Rio de Janeiro Brazil

Cytomegalovirus (CMV) and Pneumocystis jirovecii fungus are the main opportunistic microorganisms that affect transplanted individuals. Immunosuppressive drugs administered to prevent organ rejection leave the immune system vulnerable to these infections. The present report is about a kidney transplanted patient using immunosuppressants who was diagnosed with cytomegalovirus and pneumocystosis requiring admission to the intensive care unit (ICU). Female patient, 57 years old, a kidney transplanted three years ago, with comorbidities, such as systemic arterial hypertension, hypertriglyceridemia and type 2 diabetes mellitus. She was admitted to the hospital in January 2020 with a history of diarrhea, cough, malaise and weight loss of seven kg in a month. She made continuous use of the immunosuppressants tacrolimus® and mycophenolate sodium (MFS). After five days of hospitalization, she was transferred to the ICU due to refractory diarrhea, worsening renal function and respiratory pattern, requiring mechanical ventilation. Chest tomography showed changes that led to the diagnostic hypothesis of CMV pneumonia or Pneumocystis jirovecii. Treatment with Ganciclovir® and Bactrim® was started. The bronchial lavage polymerase chain reaction test confirmed the infectious condition for CMV and Pneumocystis jirovecii. Despite the drug therapy instituted, there was no improvement in the infectious condition. The patient started to present a general and progressive worsening of the clinical picture with loss of renal graft function, respiratory failure, metabolic acidosis, hemodynamic instability and severe distributive shock, evolving to death. In the present report, it was observed that after late kidney transplantation the fragility of the immune system caused by the use of immunosuppressants contributed to the development of a severe infection with CMV and Pneumocystis jirovecii. Adjusting the doses of immunos

关键词： Renal Transplantation Infections Opportunistic Immunosuppressive Agent Cytomegalovirus Pneumocystis

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Toxic Cyanobacteria in Four Brazilian Water Supply Reservoirs

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Journal of Environmental Protection（环境保护） 2012年第1期

作者： viviane Piccin-Santos Maria do Carmo Bittencourt-Oliveira

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Approach to Paroxysmal Atrial Fibrillation Type Arrhythmia in a Cardiology Service:A Case Report

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Modern Research in Inflammation 2020年第2期9卷 9-17页

作者： Miriam viviane Baron Luis Manuel Ley Dominguez Carolina Paz Mohamad Isa Gabriela Di Lorenzo Garcia Scherer Michele Paula dos Santos Vitoria Pereira Itaquy Talia Guimaraes dos Santos Julia Braga da Silveira Paulo Ricardo Martins Amanda Correa dos Santos Marcus Vinicius de Mello Pinto Janine Koepp Daiana Klein Weber Carissimi Joice Nedel Ott Carolina Goncalves Pinheiro Nathalia Ken Pereira Iketani Gabriela Feltez Bartira Ercília Pinheiro da Costa Postgraduate Program in Medicine and Health Sciences of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil Improvement of Higher Education Personnel Brazil(CAPES)Distrito FederalBrazil School of Medicine of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil School of Health and Life Sciences of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil Celulare Institute PetrópolisBrazil Undergraduate Nursing Course of the University of Santa Cruz do Sul(UNISC) Santa Cruz do SulBrazil Postgraduate Program in Health Sciences of the Faculty of Medicine of ABC(FMABC) Sao PauloBrazil Undergraduate Physiotherapy Course of the Vale do Salgado Faculty(FVS) CearáBrazil Physiotherapy of the Hospital Beneficiente Portuguesa of Belém ParáBrazil Rehabilitation Sciences of the Federal University of Health Sciences of Porto Alegre Porto AlegreBrazil Postgraduate Program in Medicine and Health Sciences School of Medicine of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS)Porto AlegreBrazil

Atrial fibrillation is a cardiac arrhythmia of high prevalence in the population, especially in the elderly. Its main electrical characteristics are the interval between two successive irregular R waves, absence of P waves and presence of f waves between QRS complexes. The most common symptoms of atrial fibrillation are irregular palpitations associated with dyspnea, dizziness, feeling tired, fatigue and general malaise, but not all patients have any symptoms. The present report presents the history of an elderly patient who arrived at the hospital’s emergency department with irregular heart rhythm and palpitations. The patient’s symptoms, associated with the electrocardiogram results, indicated paroxysmal atrial fibrillation. Electrical cardioversion was performed, and after, cardiac ablation via the femoral vein at the hospital’s cardiology service. There were no complications during the procedure. As a routine imaging exam after ablation, control esophagogastroduodenoscopy was requested to verify that there was no formation of atrio-esophageal fistula developed by the invasive ablation procedure and electrocardiogram, which showed normal sinus rhythm. The patient remained in the cardiac intensive care unit for observation for 24 hours. After the electrical cardioversion and catheter ablation procedures, the patient improved his clinical picture of atrial fibrillation and was discharged after 24 hours of hospitalization. He received treatment to perform at home, to reduce acid reflux into the esophagus and to prevent thrombosis. He did not present pulmonary thromboembolism after hospital discharge. It is believed, therefore, that this form of treatment and management of paroxysmal atrial fibrillation is effective for the solution of the proposed problem and can also serve as a reference for other professionals within the cardiology service.

关键词： Atrial Fibrillation Electrical Cardioversion Catheter Ablation Hypertension Obstructive Sleep Apnea Syndrome

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