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Acute liver injury induced by weight-loss herbal supplements

World Journal of Hepatology 2010年第11期2卷 410-415页

作者： Gary C Chen vivek.s ramanathan David Law Pauline Funchain George C Chen samuel French Boris shlopov Viktor Eysselein David Chung sonya Reicher Binh V Pham Department of Gastroenterology and Pathology Harbor UCLA Medical Center

We report three cases of patients with acute liver injury induced by weight-loss herbal supplements. One patient took Hydroxycut while the other two took Herbalife supplements. Liver biopsies for all patients dem onstrated f indings consistent with drug-induced acute liver injury. To our knowledge, we are the fi rst instit ute to report acute liver injury from both of these two typ es of weight-loss herbal supplements together as a case series. The series emphasizes the importance of taking a cautious approach when consuming herbal supp lements for the purpose of weight loss.

关键词： Hydroxycut Herbalife Hepatotoxicity Herbal Weight-loss

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Multi-modality imaging review of congenital abnormalities of kidney and upper urinary tract

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World Journal of Radiology 2016年第2期8卷 132-141页

作者： subramaniyan ramanathan Devendra Kumar Maneesh Khanna Mahmoud Al Heidous Adnan sheikh vivek Virmani Yegu Palaniappan Department of Clinical Imaging Al-Wakra Hospital Hamad Medical Corporation Department of Medical Imaging the Ottawa Hospital Department of Radiology Dr.Everett Chalmers Hospital shree Meenakshi Multi specialty Hospital

Congenital abnormalities of the kidney and urinary tract(CAKUT) include a wide range of abnormalities ranging from asymptomatic ectopic kidneys to life threatening renal agenesis(bilateral). Many of them are detected in the antenatal or immediate postnatal with a significant proportion identified in the adult population with varying degree of severity. CAKUT can be classified on embryological basis in to abnormalities in the renal parenchymal development, aberrant embryonic migration and abnormalities of the collecting system. Renal parenchymal abnormalities include multi cystic dysplastic kidneys, renal hypoplasia, number(agenesis or supernumerary), shape and cystic renal diseases. Aberrant embryonic migration encompasses abnormal location and fusion anomalies. Collecting system abnormalities include duplex kidneys and Pelvi ureteric junction obstruction. Ultrasonography(Us) is typically the first imaging performed as it is easily available, noninvasive and radiation free used both antenatally and postnatally. Computed tomography(CT) and magnetic resonance imaging(MRI) are useful to confirm the ultrasound detected abnormality, detection of complex malformations, demonstration of collecting system and vascular anatomy and more importantly for early detection of complications like renal calculi, infection and malignancies. As CAKUT are one of the leading causes of end stage renal disease, it is important for the radiologists to be familiar with the varying imaging appearances of CAKUT on Us, CT and MRI, thereby helping in prompt diagnosis and optimal management.

关键词： Congenital abnormalities Kidney Urinary tract Multi cystic dysplastic Kidneys Pelvi ureteric junction obstruction Computed tomography urography Congenital abnormalities of the Kidney and urinary tract End stage renal disease Horse shoe Kidneys

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