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Reviving Fertility:phytochemicals as Natural Allies in the Fight against Non-genetic Male Infertility

Clinical Complementary Medicine and pharmacology 2024年第1期4卷 112-128页

作者： vivek p.chavda Shreya S Sonak pankti C.Balar Krupa Vyas pranali palandurkar Komal Mule Krishna patel vivek Hala Dixa A.Vaghela Devarshi Acharya Akta Vaishnav Jimil Gandhi Vasso Apostolopoulos Department of pharmaceutics and pharmaceutical Technology L M College of PharmacyAhmedabadGujarat 380008India Bharati Vidyapeeth University’s poona College of pharmacy ErandwaneKothrudPune 411038India pharmacy section L M College of PharmacyAhmedabadGujarat 380008India University Department of pharmaceutical Sciences R.T.M Nagpur 440033India Department of pharmaceutics Khyati College of PharmacyAhmedabad 380009India IICISST Sardar Patel UniversityVallabh Vidyanagar 388120India Institute for Health and Sport Immunology and Translational ResearchVictoria UniversityMelbourneVIC 3030Australia Immunology program Australian Institute for Musculoskeletal ScienceMelbourneVIC 3021Australia

Background:Male infertility poses a growing challenge to the healthcare system,with its prevalence on the *** lifestyle,food,and addictions such as smoking,alcoholism,*** the *** several approaches are being investigated to prevent and treat this condition,each therapeutic approach has its *** medications continue to play a crucial role in the healthcare *** recent years,there has been a shift towards determining the efficacy of phytochemicals(or,herbal drugs)as ***:To evaluate the effect of various herbs,plant,metabolites,or a part of plant in management of non-genetic male ***:The male infertility-associated keywords were searched in pubMed,excluding those non-English writen papers.A total of 146 pertinent and closely connected records were included for full reading and inclusion in the systemic ***:The manuscript focuses on individual herbal drug components,their active ingredients,their role in improving the condition and quality of life,and decreasing the prevalence of male ***:Herbal medicinal plants show promising outcomes to treat male *** alternatives are appealing and have regained *** future holds promise for some of these herbal treatments to advance with many showing improved outcomes in males with infertility issues.

关键词： Male infertility plant-based management phytochemical Herbal drug Traditional Chinese medicine

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Ayurvedic and Other Herbal Remedies for Dengue: An Update

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Clinical Complementary Medicine and pharmacology 2022年第3期2卷 7-27页

作者： vivek p.chavda Anup Kumar Rittwika Banerjee Nayan Das Department of pharmaceutics and pharmaceutical Technology L M College of PharmacyAhmedabad380009GujaratIndia pharmacy Section L.M.College of PharmacyAhmedabad380058GujaratIndia

Dengue fever is a flu-like ailment propagated by female mosquitos of the Aedes aegypti *** is also known as dandaka jwara in *** is most common in the world’s subtropical and tropical climate ***,severe headache,nausea,rashes,joint pain,pain behind the eyes,muscle pain,and swollen glands are all common dengue *** not handled promptly,these symptoms can lead to more severe issues such as exhaustion,blood in the vomit,continuous vomiting,bleeding gums,restlessness,severe abdominal pain,and rapid *** there is no specific medication for dengue fever,the disease is treated by eliminating and managing the ***,there are a variety of ayurvedic remedies(like Carica papaya L.,Cissampelos pareira L.,etc.)that can help to tackle the same by strengthening the immune system and controlling *** review article provides a comprehensive overview of dengue virus infections,clinical symptoms,diagnosis,mitigation,and treatments,focusing on ayurvedic and herbal remedies.

关键词： Dengue Dengue fever Ayurveda Herbal remedy Dengue Virus COVID-19

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phytochemical Loaded Nanovehicles of Biopolymer for Breast Cancer:A Systemic Review

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Clinical Complementary Medicine and pharmacology 2023年第4期3卷 60-78页

作者： vivek p.chavda Suneetha Vuppu Rajashri Bezbaruah Lakshmi Vineela Nalla Siva Nageswara Rao Gajula pankti C.Balar Toshika Mishra Nikita Sharma Sathvika Kamaraj Thushar Suresh Anand Sairam Bedanta Bhattacharjee Department of pharmaceutics and pharmaceutical Technology LM College of PharmacyAhmedabadGujarat 380009India Department of Biotechnology ScienceInnovationand Society Research lab 115Hexagon(SMV)Vellore Institute of TechnologyVelloreTamil Nadu 632014India Institute of pharmacy Assam Medical College and HospitalDibrugarhAssam 786002India Department of pharmaceutical Science Faculty of Science and EngineeringDibrugarh UniversityDibrugarhAssam 786004India Department of pharmacy Koneru Lakshmaiah Education FoundationVaddeswaramAndhra PradeshIndia Department of pharmaceutical Analysis GITAM School of PharmacyGITAM(Deemed to be University)RushikondaVisakhapatnamAndhra Pradesh 530045India pharmacy Section LM College of PharmacyAhmedabadGujarat 380009India Departemnt of pharmacology and Toxicology Girijananda Chowdhury Institute of Pharmaceutical Science-TezpurSonitpurAssam 784501India

Background:Breast cancer is one of the most common malignancies affecting women worldwide,emphasizing the need for effective therapeutic *** derived from plants have gained significant attention due to their potential anticancer ***:This review aims to comprehensively assess the existing literature on using phytochemical-loaded for-mulations as a therapeutic approach for breast *** analyzing the available evidence,we aim to determine the potential benefits and limitations of these formulations in terms of their anticancer activity,bioavailability,and ***:A systematic search of relevant databases was conducted to identify studies investigating phytochemical-loaded formulations in the context of breast cancer *** inclusion criteria encompassed clinical trials,preclinical studies,and in-vitro experiments that reported using phytochemicals in various formulations for breast cancer *** extraction was performed to ensure the reliability and validity of the included ***:The review highlights the diverse range of phytochemicals used in different formulations for breast cancer *** suggest that these formulations exhibit promising anticancer effects by targeting mul-tiple signaling pathways in breast cancer progression,including cell proliferation,apoptosis,angiogenesis,and ***,various delivery systems,such as nanoparticles,liposomes,and micelles,have enhanced phytochemicals’bioavailability and targeted ***:phytochemical-loaded formulations hold immense potential as a therapeutic approach for breast cancer *** reviewed evidence indicates their ability to inhibit tumor growth,enhance chemotherapy effectiveness,and reduce adverse ***,further research is warranted to optimize the formulation strategies,investigate the long-term safety profiles,and conduct large-scale clinical trials to establish their efficacy and applicabi

关键词： Breast cancer Cancer phytochemicals Nanocerriers Nanoparticles

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COVAX-19 ■Vaccine:Completely blocks virus transmission to non-immune individuals

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Clinical Complementary Medicine and pharmacology 2021年第1期1卷 28-31页

作者： vivek p.chavda Lalitkumar K.Vora Disha R.Vihol Department of pharmaceutics and pharmaceutical Technology L M College of PharmacyAhmedabad-380009GujaratIndia School of pharmacy Queen’s University Belfast97 Lisburn RoadBT97BLUK pharmacy Section L.M.College of PharmacyAhmedabad-380058GujaratIndia

Various vaccine platforms are geared against COVID-19 vaccine development to produce immunogens in *** design a recombinant protein-based COVID-19 vaccine,Vaxine pty Ltd used computer models of the spike protein and its human receptor,ACE2,to identify how the virus infects human *** on this,the COVAX-19 ■vaccine is *** does reduce not only COVID-19 disease but also blocks virus shedding and *** are optimistic that this vaccine candidate could be clinically available soon with sufficient vaccine efficacy with a considerable amount of reduction in vaccination-related side effects.

关键词： COVAX-19■Vaccine SARS-CoV-2 pandemic Advax^(TM) SpikoGen■etc

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