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Six-Writings multimodal processing with pictophonetic coding to enhance Chinese language models

Frontiers of Information Technology & Electronic Engineering 2024年第1期25卷 84-105页

作者： Li WEIGANG Mayara Chew MARINHO Denise Leyi LI vitor Vasconcelos DE OLIVEIRA Department of Computer Science University of BrasiliaBrasilia 70910-900Brazil Faculty of Economics AdministrationAccounting and ActuariesUniversity of Sao PauloSao Paulo 05508-010Brazil

While large language models(LLMs)have made significant strides in natural language processing(NLP),they continue to face challenges in adequately addressing the intricacies of the Chinese language in certain *** propose a framework called Six-Writings multimodal processing(SWMP)to enable direct integration of Chinese NLP(CNLP)with morphological and semantic *** first part of SWMP,known as Six-Writings pictophonetic coding(SWPC),is introduced with a suitable level of granularity for radicals and components,enabling effective representation of Chinese characters and *** conduct several experimental scenarios,including the following:(1)We establish an experimental database consisting of images and SWPC for Chinese characters,enabling dual-mode processing and matrix generation for CNLP.(2)We characterize various generative modes of Chinese words,such as thousands of Chinese idioms,used as question-and-answer(Q&A)prompt functions,facilitating analogies by *** experiments achieve 100%accuracy in answering all questions in the Chinese morphological data set(CA8-Mor-10177).(3)A fine-tuning mechanism is proposed to refine word embedding results using SWPC,resulting in an average relative error of≤25%for 39.37%of the questions in the Chinese wOrd Similarity data set(COS960).The results demonstrate that SWMP/SWPC methods effectively capture the distinctive features of Chinese and offer a promising mechanism to enhance CNLP with better efficiency.

关键词： Chinese language model Chinese natural language processing(CNLP) Generative language model Multimodal processing Six-Writings

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Seismic Risk Model for the Beijing–Tianjin–Hebei Region, China:Considering Epistemic Uncertainty from the Seismic Hazard Models

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International Journal of Disaster Risk Science 2024年第3期15卷 434-452页

作者： Jian Ma Katsuichiro Goda Kai Liu Silva vitor Anirudh Rao Ming Wang Key Laboratory of Earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake Administration Key Laboratory of Earthquake Disaster Mitigation Ministry of Emergency Management School of National Safety and Emergency Management Beijing Normal University Shenzhen Key Laboratory of Urban Disasters Digital Twin Department of Earth Sciences Western University Global Earthquake Model Foundation

This study presents a probabilistic seismic risk model for the Beijing–Tianjin–Hebei region in China. The model comprises a township-level residential building exposure model, a vulnerability model derived from the Chinese building taxonomy,and a regional probabilistic seismic hazard model. The three components are integrated by a stochastic event-based method of the OpenQuake engine to assess the regional seismic risk in terms of average annual loss and exceedance probability curve at the city, province, and regional levels. The novelty and uniqueness of this study are that a probabilistic seismic risk model for the Beijing–Tianjin–Hebei region in China is developed by considering the impact of site conditions and epistemic uncertainty from the seismic hazard model.

关键词： Beijing–Tianjin–Hebei region Epistemic uncertainty Seismic risk assessment Seismic risk model

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Preliminary Tests of a Kerma-Area Product (KAP) Meter to Be Used as a Monitor Chamber in a Conventional Diagnostic X Ray System

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Journal of Modern Physics 2015年第4期6卷 483-489页

作者： Eduardo Correa Regina Medeiros Maria da Penha Potiens vitor vivolo Nathalia Costa Camila Murata Cristina Kikuti Instituto de Pesquisas Energéticas e Nucleares (IPEN-CNEN) Universityof Sao Paulo (USP) Sao Paulo Brazil Federal University of Sao Paulo (UNIFESP) Sao Paulo Brazil

This study presents the results of the preliminary tests performed using a kerma-area product (KAP) meter in order to verify its usefulness as a monitor chamber in a clinical X ray system, which will be used in ionization chambers’ quality control program. The tests performed were repeatability, surface measurement uniformity, linearity with tube current, measurement variation changing the distance and field size, KAP chamber radiation attenuation, and energy dependence. The KAP meter has presented a good repeatability (a maximum variation of 0.4%);its surface has a homogeneous response (a maximum variation of 1.0% among the different irradiated regions);the response is linear with the tube current and the variation of the PKA along the distance is less than 3.43%. On the other hand, the results obtained for chamber attenuation and energy dependence show that some corrections must be applied when the measurements are made. The results have shown a good performance of the KAP meter, confirming that it is possible to use this instrument as a monitor chamber. However, it is important to highlight that some correction factors for energy dependence and chamber radiation attenuation must be considered.

关键词： KAP Meter Quality Control Diagnostic Radiology Monitor Chamber

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Extrahepatic cholestasis associated with paracoccidioidomycosis:Challenges in the differential diagnosis of biliopancreatic neoplasia

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2531-2540页

作者： Jose Sebastiao dos Santos vitor de Moura Arrais William Jose Rosseto Ferreira Ricardo Ribeiro Correa Filho Mariangela Ottoboni Brunaldi Rafael Kemp Ajith Kumar Sankanrakutty Jorge Elias Junior Fernando Bellissimo-Rodrigues Roberto Martinez Edson Zangiacomi Martinez Jose Celso Ardengh Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP) Departamento de Cirurgia e AnatomiaRibeirao Preto 14049-900Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de PatologiaRibeirao Preto 14048900Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Imagens MédicasHematologia e Oncologia ClínicaRibeirao Preto 14048900Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Medicina SocialRibeirao Preto 14015-010Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Clínica MédicaRibeirao Preto 14015-010Sao PauloBrazil Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Cirurgia e AnatomiaRibeirao Preto 14049-900Sao PauloBrazil and Hospital MoriahServico de Endoscopia DigestivaSao Paulo 04084-002Sao PauloBrazil

BACKGROUND Paracoccidioidomycosis(PCM)may involve the hepatic pedicle and peripan creatic lymph nodes,cause damage to the bile duct and manifest,exceptionally,in combination with extrahepatic cholestasis(EHC),making investigation and treatment *** To investigate the management of patients with visceral PCM admitted with *** All patients diagnosed with PCM treated in a public,tertiary teaching hospital between 1982 and 2020 were retrospectively *** also identified with EHC were allocated to two groups according to the treatment approach for the purpose of comparing clinical,laboratory,and imaging findings,resources used for etiological diagnosis,treatment results,and *** analyses were performed using the linear mixed-effects model(random and fixed effects),which was adjusted using the PROC MIXED procedure of the SAS®9.0 software,and Fisher’s exact *** Of 1645 patients diagnosed with PCM,40(2.4%)had *** these,20(50.0%)lived in the rural area and 29(72.5%)were men,with a mean age of 27.1 years(3-65 years).Jaundice as first symptom and weight loss of at least 10 kg were observed in 16 patients(40.0%),and a mass in the head of the pancreas was observed in 8(20.0%).The etiological diagnosis was made by tissue collection during surgery in 4 cases(10.0%)and by endoscopic methods in 3 cases(7.5%).Twenty-seven patients(67.5%)received drug treatment alone(Group 1),whereas 13(32.5%)underwent endoscopic and/or surgical procedures in combination with drug treatment(Group 2).EHC was significantly reduced in both groups(40.7% in Group 1,with a mean time of 3 months;and 38.4% in Group 2,with a mean time of 7.5 months),with no statistically significant difference between *** recurrence rates,associated mainly with treatment nonadherence,were similar in both groups:37% in Group 1 and 15.4% in Group *** mortality rate was 18.5% in Group 1 and 23% in Group 2,with survival estimates of 71.3% and 72.5%,respectively,with

关键词： Cholestasis Jaundice Obstructive Blastomycosis Paracoccidioides Diagnosis Treatment

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Endoscopic sleeve gastroplasty:a narrative review on historical evolution,physiology,outcomes,and future standpoints

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Chinese Medical Journal 2022年第7期135卷 774-778页

作者： vitor Ottoboni Brunaldi Manoel Galvao Neto Center for Digestive Endoscopy Surgery and Anatomy DepartmentRibeirão Preto Faculty of MedicineUniversity of São Paulo14015-010 Ribeirão PretoBrazil Endovitta Institute 04102-001 São PauloBrazil ABC Faculty of Medicine 09060-870 Santo AndreBrazil

Since its first description in 2013,robust evidence supporting the efficacy and safety of the endoscopic sleeve gastroplasty(ESG)has been on the rise.A large case series and meta-analysis report supported results up to 24 months,while some other studies already described 5-year *** associated with pharmacotherapy,the ESG may help one to achieve weight loss similar to that of surgical sleeve *** the results of the ongoing randomized trials on ESG are awaited,currently available data support the clinical use of the ESG,especially for patients who are refusing or unfit for bariatric surgery.

关键词： Endoscopy Bariatric Obesity Overweight Sleeve Suturing

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Oxidative stress in N88S seipinopathy:novel insights into the mechanisms of neurodegeneration and therapeutic avenues

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中国神经再生研究：英文版 2023年第8期18卷 1719-1720页

作者： Vítor Costa vitor Teixeira i3S-Instituto de Investigação e Inovação em Saúde Universidade do PortoPortoPortugal Yeast Signalling Networks IBMC-Instituto de Biologia Molecular e CelularUniversidade do PortoPortoPortugal ICBAS Instituto de Ciências Biomédicas Abel SalazarUniversidade do PortoPortoPortugal

Lipid droplets (LDs) are ubiquitous cellular orga nelles that perform functions mostly dedicated to energy homeostasis and lipid *** neutral lipid depots (triacylglycerol,sterol esters),they can be rapidly mobilized through lipase-mediated hydrolysis (lipolysis) or via lipophagy,a specific form of autophagy devoted to consumption of LDs inside the lysosome.

关键词： hydrolysis insight devoted

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Possible high COVID-19 airborne infection risk in deep and poorly ventilated 2D street canyons

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建筑模拟(英文) 2023年第9期16卷 1617-1628页

作者： vitor Lavor Omduth Coceal Sue Grimmond Jian Hang Zhiwen Luo School of the Built Environment University of ReadingReadingUK Department of Meteorology University of ReadingReadingUK School of Atmospheric Sciences Guangdong Province Key Laboratory for Climate Change and Natural Disaster StudiesSun Yat-sen UniversityGuangzhouChina Welsh School of Architecture Cardiff UniversityCardiffUK

Despite the widespread assumption that outdoor environments provide sufficient ventilation and dilution capacity to mitigate the risk of COVID-19 infection,there is little understanding of airborne infection risk in outdoor urban areas with poor *** address this gap,we propose a modified Wells-Riley model based on the purging flow rate(QPFR),by using computational fluid dynamics(CFD)*** model quantifies the outdoor risk in 2D street canyons with different approaching wind speeds,urban heating patterns and aspect ratios(building height to street width).We show that urban morphology plays a critical role in controlling airborne infectious disease transmission in outdoor environments,especially under calm winds;with deep street canyons(aspect ratio>3)having a similar infection risk as typical indoor *** ground and leeward wall heating could reduce the risk,windward heating(e.g.,windward wall~10 K warmer than the ambient air)can increase the infection risk by up to 75%.Our research highlights the importance of considering outdoor infection risk and the critical role of urban morphology in mitigating airborne infection *** identifying and addressing these risks,we can inform measures that may enhance public health and safety,particularly in densely populated urban environments.

关键词： airborne infection risk street canyon urban ventilation wall heating CFD modelling

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In Silico and in Vitro Analysis of Pyrazolone Derivatives against Zika Virus and Identification of Potential NS5 Methyltransferase Inhibitors by Molecular Docking

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Journal of Biosciences and Medicines 2024年第7期12卷 214-229页

作者： Luciene Soares Silva Tiago Soares Barbosa Maria Leonisa Sanchez-Nuñez Aldenise Mont Serrat Rosa da Silva vitor Won-Held Rabelo Leonardo dos Santos Corrêa Amorim Leonardo Alves Miceli Percilene Fazolin Vegi Alice Bernardino Helena Carla Castro Izabel Christina Nunes de Palmer Paixão Science and Biotechnology Graduate Program Department of Cellular and Molecular Biology Institute of Biology Fluminense Federal University Niteri Brazil Science and Biotechnology Graduate Program Department of Cellular and Molecular Biology Institute of Biology Fluminense Federal University Niterói Brazil Laboratory of Antibiotics Biochemistry Teaching and Molecular Modeling Institute of Biology Fluminense Federal University Niterói Brazil Laboratory of Organic Chemistry at the Institute of Chemistry Institute of Biology Fluminense Federal University Niterói Brazil

Zika virus (ZIKV), a mosquito-borne flavivirus, has been associated with benign infections for decades. However, it has become a public health concern due to its association with severe fetal and neurological complications. Although many efforts have been made to control ZIKV infection, approved vaccines or antiviral drugs are still lacking. Consequently, the development of new effective anti-ZIKV agents is urgently needed. In this context, we investigated the antiviral potential of pyrazolone derivatives against ZIKV replication using in silico and in vitro methods. The four pyrazolone derivatives evaluated (1a, 1b, 1c, and 1d) inhibited over 50% of ZIKV replication with low cytotoxicity. Among them, compound 1b exhibited the most potent activity (EC50 = 4.3 μM) and the highest selectivity (SI = 342). Mechanism of action studies indicated that these compounds act at early stages of virus replication, and compound 1b can also directly inactivate ZIKV particles. Molecular docking studies suggested that these compounds can bind to and block the activity of ZIKV NS5 methyltransferase. Finally, pharmacokinetic and toxicological predictions have reinforced the safety and drug-like profiles of these derivatives. In conclusion, the pyrazolone scaffold proved to be valuable for anti-ZIKV drug development, and the derivatives studied deserve further investigation.

关键词： Zika Pyrazolone NS5 Methyltransferase Antivirals

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The Use of Secondary Grape Biomass in Beef Cattle Nutrition on Carcass Characteristics, Quality and Shelf Life of Meat

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Food and Nutrition Sciences 2024年第6期15卷 447-469页

作者： vitor L. Molosse Guilherme L. Deolindo Rafael V. P. Lago Bruna Klein Claiton A. Zotti Marcelo Vedovato Marcylene V. da Silveira Priscila M. Copetti Maria R. C. Schetinger Juscivete F. Favero Eliana L. Fiorentin Aleksandro S. da Silva Universidade do Estado de Santa Catarina (UDESC) Chapec Brazil Department of Animal Science UDESC Chapec Brazil Department of Animal Science Universidade do Oeste de Santa Catarina Xanxere Brazil Dean Lee Research and Extension Center Louisiana State University Alexandria LA USA Department of Biochemistry Universidade Federal de Santa Maria Santa Maria Brazil Department of Medicina Veterinria UNOCHAPEC Chapec Brasil

We determined whether the inclusion of 100 g/kg dry matter of grape pomace silage (GPS) and grape pomace bran (GPB) as substitutes for other traditional fiber sources in the diet of steers (Charolais x Nellore) would improve carcass characteristics, meat quality and composition, and shelf life. Twenty-four animals (248 ± 19.32 kg of initial body weight) were fed a high concentrate diet for 121 days. Carcass characteristics were measured, and the longissimus dorsi muscle was analyzed for fatty acid (FA) profile and composition. The meat was sliced and stored in air-permeable packages for 10 days. On each sampling day (d 1, 3, 7, and 10), oxidative stability, bacterial load, lipid and protein oxidation, and staining were analyzed. The experimental diets influenced the pH of cold carcasses only. The GPS group had a higher pH than the control. The GPS and GPB groups showed improved oxidant status (i.e., lower lipid peroxidation and concentrations of reactive oxygen species were in the meat of both groups than in control). On the first day of storage, the antioxidant enzyme glutathione S-transferase activity was more significant in the meat of the GPS and GPB groups than in the control. The bacterial loads in the meat were attenuated by GPS inclusion;there were lower total coliform counts and a trend toward lower counts for enterobacteria in the control group. The diets altered the FA profile of the meat;i.e., the GPB diet allowed for a more significant amount of the n-6 omegas in the meat, while the GPS diet showed a tendency for a more significant amount of n-6 and 9 omegas. Both diets (GPS and GPB) increased the amounts of long-chain FAs. The GPS diet decreased saturated FA levels. We conclude that the dietary treatments GPS and GPB are a promising alternative to maintain meat quality standards throughout in real-world retail conditions. These treatments gave rise to an improvement in the nutritional value of the meat due to the more significant amounts of FAs that im

关键词： Animal Nutrition Antioxidant Biomass Grape Meat Quality Microbiology Residue

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A Building Classification System for Multi-hazard Risk Assessment

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International Journal of Disaster Risk Science 2022年第2期13卷 161-177页

作者： vitor Silva Svetlana Brzev Charles Scawthorn Catalina Yepes Jamal Dabbeek Helen Crowley Risk Section Global Earthquake Model27100 PaviaItaly Department of Civil Engineering University of British ColumbiaVancouverBC V6T 1Z4Canada SPA Risk LLC DenverCO 80207USA Department of Civil Engineering An-Najah National UniversityNablusState of Palestine Seismic Risk Section 27100 EucentrePaviaItaly

A uniform and comprehensive classification system, often referred to as taxonomy, is fundamental for the characterization of building portfolios for natural hazard risk assessment. A building taxonomy characterizes assets according to attributes that can influence the likelihood of damage due to the effects of natural *** the scope of the Global Earthquake Model(GEM)initiative, a building taxonomy(GEM Building Taxonomy V2.0) was developed with the goal of classifying buildings according to their seismic vulnerability. This taxonomy contained 13 building attributes, including the main material of construction, lateral load-resisting system, date of construction and number of stories. Since its release in2012, the taxonomy has been used by hundreds of experts working on exposure and risk modeling efforts. These applications allowed the identification of several limitations, which led to the improvement and expansion of this taxonomy into a new classification system compatible with multi-hazard risk assessment. This expanded taxonomy(named GED4ALL) includes more attributes and several details relevant for buildings exposed to natural hazards beyond earthquakes. GED4ALL has been applied in several international initiatives, enabling the identification of the most common building classes in the world, and facilitating compatibility between exposure models and databases of vulnerability and damage databases.

关键词： Disaster risk Exposure Multihazard Taxonomy

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