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Journal of Environmental Protection 2011年第9期2卷 1149-1161页

作者： Julie Burtt Michael Ilin Rachel Lane Patsy Thompson Marcelle Phaneuf pascale Reinhardt 不详

The radium and uranium processing industry exists in Port Hope, Ontario, since 1932. Between 1932 and 1966, most of the waste material from these industries was deposited throughout the town. During these years, waste management practices did not prevent the spread of contamination. Several environmental and health studies have been conducted to assess the potential contamination effects in the Port Hope Community over the last 70 years. The current study used a weight of evidence approach to assess the types and levels of contaminants of concern in the environment, and the potential human exposure to these contaminants. Their toxicological and radio-toxicological properties were also assessed to determine their potential health effects. The results of these assessments were further compared to findings of earlier epidemiological studies of Port Hope residents and nuclear industry workers. The conclusions of this study indicated that: 1) Levels of exposure to radioactive and non-radioactive contaminants in Port Hope are below levels known to cause adverse health effects. 2) Epidemiological studies provide no evidence of health effects as a result of past and present activities of the Port Hope nuclear industries. 3) The environmental risk assessments and the epidemiological studies are consistent and support each other. 4) Port Hope’s findings are consistent with the results of over 40 epidemiological studies conducted elsewhere on populations living around similar facilities or exposed to similar environmental contaminants.

关键词： Uranium Radiation Cancer Environment

Elderly Lung Cancer Patients and Radiochemotherapy: A Review

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Journal of Cancer Therapy 2012年第4期3卷 359-363页

作者： Francesco Fiorica Antonio Stefanelli Silvia Princivalle Giuliana pascale Francesco Cartei department of Radiation Oncology University Hospital Ferrara Ferrara Italy

More than 60% of lung cancer patients in Europe and the USA are older than 65 years at the time of diagnosis. despite this, elderly patients are generally under-represented in clinical trials. That being so, a general consensus on how to treat elderly patients is still far from being achieved. In this review, we address some of the issues and challenges surrounding the treatment of older cancer patients and radiochemotherapy. We discuss the existing evidence related to radio-chemotherapy in the elderly, focusing primarily on the lung cancer (NSCLC and SCLC) most commonly seen in older patients, and making general treatment recommendations.

关键词： Radiochemotherapy Lung Cancer Elderly Patients Geriatric Oncology Clinical Trials

A Systemic Approach to Evaluate the Flood Vulnerability for an Urban Study Case in Southern Italy

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Journal of Water Resource and Protection 2014年第4期6卷 351-362页

作者： Raffaele Albano Aurelia Sole Francesco Sdao Luciana Giosa Andrea Cantisani Stefania pascale School of Engineering University of Basilicata Potenza Italy

Currently, the urban flooding is one of the most concerning problems in hydraulic protection, both for the enormous number of people and the different elements (buildings, roads, vehicles, and so on) potentially exposed to risk, as well as the complexity of the territory at issue. At the practical level, vulnerability indicators are often predictably too narrow in their coverage of aspects of vulnerability. An important need remains to produce more conceptually informed vulnerability indicators or parameters and more satisfactory operational tools to assess weaknesses and resilience in coping with natural risks. In this paper, we present an innovative methodology that adopts a systemic approach to evaluate the vulnerability due to a flood scenario. The operative efficiency of the proposed GIS tool is validated in pilot application site, i.e. an urban area in Puglia Region, Southern Italy, on the basis of, studies surveys and damages carried out from a recent flood event occurred in the area. The model evaluates the direct structural damages and explores the potential operating conditions of the road network in case of the flood event. The resulting vulnerability assessment tool can guide evaluators towards a comprehensive understanding of strengths and fragilities of a territory and community where a flood occurs embedding and integrating as much as possible the multifaceted and articulated nature of an urban system.

关键词： Urban Flooding Vulnerability GIS Systemic Approach

Effects of Light Radiation Absoption on the Resistance of Sweet Potato Starch-Based Bioplastics

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Journal of Materials Science and Chemical Engineering 2022年第2期10卷 44-52页

作者： Aristide Herlyn Wilfrid Nakavoua Emmanuelle Surya Ouenadio pascale Ursula Nkoua-Ouassamo Vincent Verney Laboratory of Natural Substances Chemistry (IRSEN) Brazzaville Congo Laboratory for The Valorisation of Agri-Resources Ecole Normale Superieure Politechnique (ENSP) Marien Ngouabi University Brazzaville Congo UMR 6296 Team design of Polymers and Macromolecules Scientist Set Cézeaux Institute of Chemistry of Clermont-Ferrand (ICCF) Clermont-Ferrand French

The strength of starch-based bioplastics is a challenge, we tried to overcome this limitation by using electromagnetic radiation in the visible range. Synthetically obtained retrograde bioplastics were subjected to radiation from an Edison-type incandescent lamp. A cross-linked network is obtained within the bioplastic matrix considerably attenuating the usual hygroscopicity of starch and increasing the ability to resist rupture. After this positive behavior, the bioplastics were colored in order to optimize the action of light radiation. The results show a stronger and more compact bioplastic. The green-colored bioplastics show the best performance in the optimization of the resistance.

关键词： Bioplastics Starch Sweet Potato Radiation and Light Stress

Juvenile ferric iron prevents microbiota dysbiosis and colitis in adult rodents

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World Journal of Gastroenterology 2012年第21期18卷 2619-2629页

作者： Chourouk Ettreiki pascale Gadonna-Widehem Irène Mangin Mose Coёffier Carine delayre-Orthez Pauline M Anton Egeal Unit LaSalle Beauvais Polytechnic Institute60026 Beauvais France Biology Lab National Conservatory of Arts and Crafts75003 Paris France INSERM UMR 1073 School of Medicine Rouen University76183 Rouen France

AIM: To assess whether juvenile chronic ferric iron ingestion limit colitis and dysbiosis at adulthood in rats and mice. METHODS: Two sets of experiments were designed. In the first set, recently weaned mice were either orally administered ferrous (Fe2+) iron salt or ferric (Fe3+) microencapsulated iron for 6 wk. The last week of experiments trinitrobenzene sulfonic acid (TNBS) colitis was induced. In the second set, juvenile rats received the microencapsulated ferric iron for 6 wk and were also submitted to TNBS colitis during the last week of experiments. In both sets of experiments, animals were sacrificed 7 d after TNBS instillation. Severity of the inflammation was assessed by scoring macroscopic lesions and quantifying colonic myeloperoxidase (MPO) activity. Alteration of the microflora profile was estimated usingquantitative polymerase chain reaction (qPCR) by measuring the evolution of total caecal microflora, Bacteroidetes, Firmicutes and enterobacteria. RESULTS: Neither ferrous nor ferric iron daily exposures at the juvenile period result in any effect in control animals at adulthood although ferrous iron repeated administration in infancy limited weight gain. Ferrous iron was unable to limit the experimental colitis (1.71 ± 0.27 MPO U/mg proteinvs 2.47 ± 0.22 MPO U/mg protein in colitic mice). In contrast, ferric iron significantly prevented the increase of MPO activity (1.64 ± 0.14 MPO U/mg protein) in TNBS-induced colitis. Moreover, this positive effect was observed at both the doses of ferric iron used (75 and 150 mg/kg per day po - 6 wk). In the study we also compared, in both rats and mice, the consequences of chronic repeated low level exposure to ferric iron (75 mg/kg per day po - 6 wk) on TNBS-induced colitis and its related dysbiosis. We confirmed that ferric iron limited the TNBS-induced increase of MPO activity in both the rodent species. Furthermore, we assessed the ferric iron incidence on TNBS-induced intestinal microbiota dysbiosis. At firs

关键词： Chronic ferric iron supplementation Experimental colitis Microflora dysbiosis Rat Mice

移动的风景——马克·帝格朗尚和茹小凡的画作

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东方艺术 2010年第1期 66-73页

作者： pascale Le Thorel 对画空间

“在生活中会有仙人掌，我自豪地知道……”这是Jacques Dutronc一首歌曲的开头．马克·帝格朗尚的画里偶尔会有仙人掌，茹小凡则有时画的是奇特的植物，看上去似乎像仙人掌。

关键词：马克画作风景仙人掌歌曲

工业集聚、城镇化与环境污染——基于非线性门槛效应的实证研究

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科技管理研究 2017年第11期37卷 217-223页

作者：王素凤 pascale Champagne 潘和平冯南平王洪波安徽建筑大学管理学院合肥安徽230601 加拿大女王大学土木工程学院合肥工业大学管理学院合肥安徽230009

利用中国30个省级行政区2000—2014年的面板数据,运用门槛回归方法,以工业集聚为门槛变量,实证分析工业集聚及其与城镇化的耦合效应对污染排放的影响,并将样本总体划分为东部、中部、西部和东北4组检验工业集聚环境外部性的区域差异。... 详细信息

利用中国30个省级行政区2000—2014年的面板数据,运用门槛回归方法,以工业集聚为门槛变量,实证分析工业集聚及其与城镇化的耦合效应对污染排放的影响,并将样本总体划分为东部、中部、西部和东北4组检验工业集聚环境外部性的区域差异。研究结果表明:工业集聚与环境污染的关系呈倒U型特征;工业集聚通过推动经济发展减少污染物排放;工业集聚与城镇化的良性互动显著降低了环境污染水平;城镇化对工业集聚环境污染效应的门槛位置有重要影响,在四类地区中,城镇化水平较高的东部省份的门槛值明显低于其它地区。

关键词：工业集聚环境污染门槛模型城镇化区域差异

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机器人能“杀死”性别歧视吗

中国企业家 2016年第1期52卷 27-29页

作者： pascale Fung 香港科技大学

推荐引擎通过调查用户的各项特质,包括性别和种族,以此推出在它眼中最适合的广告,换取更高的点击率如果机器人可以免受我们自身偏见的影响,那么它们一定可以发挥积极的作用。随着机器人对人类情感与社会需求的理解愈发到位,人工智能科... 详细信息

推荐引擎通过调查用户的各项特质,包括性别和种族,以此推出在它眼中最适合的广告,换取更高的点击率如果机器人可以免受我们自身偏见的影响,那么它们一定可以发挥积极的作用。随着机器人对人类情感与社会需求的理解愈发到位,人工智能科技可以从多方面人手,帮助女性提升在工作领域的参与度。为什么男性和女性会在网上看到不一样的招聘广告？纵观对智能机器的颇多微词,其中一条尤为醒目,那与谷歌创建的广告定位算法所提供的招聘广告有关。根据卡内基·梅隆大学的研究显示,谷歌的高薪职位推荐存在重男轻女的现象。研究人员模拟创立了求职者的用户资料,这些用户从未有过网页浏览历史,除了性别不同外别无二致。

关键词：性别歧视机器人招聘广告智能科技社会需求人类情感广告定位重男轻女

Long term outcome and quality of life after pelvic exenteration for recurrent endometrial and cervical cancers

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Open Journal of Obstetrics and Gynecology 2013年第5期3卷 19-27页

作者： Charlotte Ngo Christelle Abboud Paul Meria Virginie Fourchotte pascale Mariani Bernard Baranger Xavier Sastre Caroline Malhaire Anne-Cécile Philippe Suzy Scholl Anne de la Rochefordière Séverine Alran departments of Surgical Oncology Institut Curie Gynaecological Cancer Study GroupInstitut CurieParisFrance Université Paris descartes Institut Curie Gynaecological Cancer Study GroupInstitut CurieParisFrance departments of Pathology Institut Curie Gynaecological Cancer Study GroupInstitut CurieParisFrance departments of Radiotherapy Institut Curie Gynaecological Cancer Study GroupInstitut CurieParisFrance departments of Medical Oncology Institut Curie Gynaecological Cancer Study GroupInstitut CurieParisFrance departments of Medical Imaging Institut Curie Gynaecological Cancer Study GroupInstitut CurieParisFrance

Introduction: Pelvic exenteration can cure recurrent gynecological malignancies. However, treatment morbidity is over 50% in radiated pelves. We evaluated the outcome, the morbidity and the quality of life after exenteration. Methods: Patients who underwent an exenteration for recurrent cervical or endometrial cancer in our institution between 1999 and 2011 were retrieved. Survival rates were calculated according to Kaplan-Meier method and compared using the logrank test. The EORTC QLQ-C30 and QLQ-CX24 questionnaires were sent to patients alive in January 2012. Results: We identified 25 patients: 17 (68%) had cervical cancer and 8 (32%) endometrial cancer. 92% of them had received radiotherapy previously. All patients had a central pelvic recurrence, within a median time of 30 months [4 - 384] from initial treatment. Early complications requiring a re-laparotomy occurred in 9 patients (36%). Late complications included 2 (8%) fistulas, 2 (8%) occlusion and 1 (4%) ureteral stenosis. Complete resection was obtained in 92% of patients. Disease Free and Overall survival rates were better in cervical rather than in endometrial cancer (median DFS in months 17 [2 - 145] vs 9.5 [3 - 21], p = 0.064, median OS in months 20 [2 - 145] vs 13 [4 - 42], p = 0.019). 69% of patients answered the quality of life questionnaires. Mean global quality of life score was 45 on a scale of 0 - 100, none of the patients had a sexual activity. Conclusions: Morbidity of exenteration remains high and quality of life is altered. Endometrial cancer is associated with a poorer prognosis. In those patients, exenteration should be put in balance with best supportive care.

关键词： Pelvic Exenteration Quality of Life Recurrent Cervical Cancer Recurrent Endometrial Cancer

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纽约Nobu餐厅

现代装饰 2017年第9期 180-181页

作者： pascale Girardin 彭佳 Rockwell Group

美国建筑与室内设计公司Rockwell Group最近与加拿大陶瓷艺术家pascale Girardin合作,完成了纽约一间新的Nobu餐厅的设计。pascale Girardin为餐厅特别打造了三件艺术装置,让餐厅更显独特。

关键词： Nobu 陶瓷艺术家美国建筑 Rockwell 室内设计蓝色光日式