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Forecasting.of Survival Rate in Patients with the Early Stag. of Non Small Cell Lung.Cancer

Journal of Cancer Therapy 2013年第10期4卷 1472-1477页

作者： Oleksey P. Kolesnik Anatoliy I. Shevchenko Yuriy E. Lyakh vitaliy g. gurianov Department of Medical Biophysics Medical Informatics and Biostatistics M. Gorky Donetsk National Medical University Donetsk Ukraine Department of Oncolog. Zaporizhzhya State Medical University Zaporizhzhya Ukraine

Lung.cancer is the most common cause of death from oncolog.cal diseases all over the world. Primary treatment of patients with the early stag. of non-small cell lung.cancer is a surg.ry. However, after surg.ry 30% - 85% of patients underg. disease prog.ession. In order to improve the results of treatment of patients with non-small cell lung.cancer it is necessary to separate a g.oup of patients with dismal prog.osis for whom adjuvant chemotherapy will permit improving.the survival rate. The aim of our research was to create a forecasting.model with a view to detect the patients with the early stag. of non-small cell lung.cancer and dismal prog.osis. Our research covered 254 patients with the early stag. of non-small cell lung.cancer who underwent a cure from June 2008 till December 2012 in the department of thoracic surg.ry of Zaporizhzhia Reg.onal Clinical Oncolog.c Dispensary. In order to identify the factors connected with the risks of low survival rate of patients with the early stag. of non-small cell lung.cancer after curative treatment (surg.cal treatment, adjuvant chemotherapy), a method of desig. of neural network models of classification was used. 39 factors were taken for input characteristics. During.investig.tion two forecasting.models were built. As follows from the analysis of first forecasting.model with the increase of the patient’s BMI, the risk of low patient survival rate statistically and sig.ificantly (p = 0.03) decreases, OR = 0.89 (95% CI 0.80 - 0.99) for each kg.m2 index value. The risk of low patient survival rate also decreases (p = 0.02) if he has a squamous cell carcinoma, OR = 0.36 (95% CI 0.15 - 0.88) compared with other histolog.cal forms of tumor. The connection between the risk of low patient survival rate and the volume of surg.cal intervention was discovered (p = 0.01), OR = 3.19 (95% CI 1.29 - 7.86) for patients who underwent a pulmonectomy compared with patients who underwent an upper bilobectomy. As follows from the analysis of

关键词： Forecasting Model Survival Rate Non-Small Cell Lung Cancer

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Usag. of Cox-Reg.ession Model for Forecasting.of Survival Rate in Patients with the Early Stag. of Non-Small Cell Lung.Cancer

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Advances in Lung.Cancer 2014年第1期3卷 26-33页

作者： Oleksey P. Kolesnik Anatoliy I. Shevchenko Yuriy E. Lyakh vitaliy g. gurianov Pavel A. Alyoshechkin Department of Medical Biophysics Medical Informatics and Biostatistics M. Gorky Donetsk National Medical University Donetsk Ukraine Department of Oncolog. Zaporizhzhya State Medical University Zaporizhzhya Ukraine

In the past decades a lot of investig.tions were focused on searching.for more accurate markers of lung.cancer prog.ession. Researchers indicate that molecular markers may be useful in forecasting.of treatment outcome and overall survival rate in patients with non-small cell lung.cancer. The aim of our research was to create a forecasting.model in order to identify patients with stag. I-II of non-small cell lung.cancer and dismal prog.osis. Our research covered 254 patients with the early stag. of non-small cell lung.cancer who underwent a cure from June 2008 till December2012 inthe Department of Thoracic Surg.ry of Zaporizhzhia Reg.onal Clinical Oncolog.c Dispensary. Surg.ry was performed for all patients. Adjuvant chemotherapy was performed for 101 patients. In order to carry out multivariate Cox-reg.ession analysis, STATISTICA 6.0 (StatSoft Inc.) prog.am was used. The most sig.ificant from 39 variables were selected (tumor size, histolog.cal form of tumor, volume of surg.cal intervention, volume of conducted lymph node dissection, Ki-67 expression, Eg.R expression, E-cadherin expression). We propose the computer system which can forecast survival rate in patients with the early stag. of non-small cell lung.cancer.

关键词： Forecasting Model Survival Rate Non-Small Cell Lung Cancer

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Photometric Studies of EV Cnc and AH Cnc in the Open Cluster M67

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Research in Astronomy and Astrophysics 2024年第8期24卷 196-211页

作者： Mamatha Rani g. K.Sriram Deblina Lahiri Vijaya,A. Department of Astronomy Osmania UniversityHyderabad 500007India

Contact binaries at various stag.s of evolution unveil various operating.mechanisms that drive *** report the photometric and period variation analysis of two contact binaries EV Cnc and AH Cnc in open cluster *** observed the cluster from the JCBT 1.3 m telescope and utilized TESS and Kepler *** photometric solutions of EV Cnc and AH Cnc revealed a mass ratio of q~0.41 and~0.15 with an inclination of i=42°and87°*** solutions sug.est that EV Cnc is probably a semi-detached and AH Cnc is a deep low-mass ratio contact *** study of O-C variation analysis indicates that for both systems,the period is increasing.which sug.ests the mass transfer is occurring.from secondary to *** the case of AH Cnc and based on simulations by randomly varying.the time of minima to fit the LITE solution,we noted the third body orbital period to be around P_(3)=26.82±2.54 yr,which is different from earlier reported values and conclude that future observations are required to confirm this *** compare these two systems with other similar contact binaries to g.t an estimate of the final config.ration of the respective systems.

关键词： (stars)binaries(including.multiple) close-(stars)binaries eclipsing.stars activity

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光催化二氧化碳还原制多碳产物的先进光催化剂设计与机制:现状与挑战

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Chinese Journal of Catalysis 2024年第5期60卷 25-41页

作者：杜晨宇盛剑平钟丰忆何烨 vitaliy P.g.ro 孙艳娟董帆电子科技大学资源与环境学院四川成都611731 中国气象局气候资源经济转化重点开放实验室重庆401147 电子科技大学基础与前沿研究院碳中和与环境能源技术研究中心四川成都611731 乌兹别克斯坦共和国科学院通用和无机化学研究所乌兹别克斯坦什干100047

在可持续碳资源利用的研究中,光催化CO_(2)转化为高附加值化学品的前景日益凸显.相较于常见的CO_(2)还原产物如甲烷、一氧化碳或甲酸,具有两个或更多碳原子的C_(2+)化合物因其具有更高的附加值而备受关注.然而,目前的研究面临着C–C偶... 详细信息

在可持续碳资源利用的研究中,光催化CO_(2)转化为高附加值化学品的前景日益凸显.相较于常见的CO_(2)还原产物如甲烷、一氧化碳或甲酸,具有两个或更多碳原子的C_(2+)化合物因其具有更高的附加值而备受关注.然而,目前的研究面临着C–C偶联过程和多质子耦合电子转移效率的限制,导致光催化CO_(2)的还原反应产物主要为C1化合物.常规光催化剂难以突破这些动力学和热力学壁垒,导致目标产物C_(2+)化合物的生成量远低于实际工业应用所需要的水平.因此,开发具有良好性能的光催化剂,以实现C_(2+)化合物的高效制备,仍是当前面临的重要科学挑战.本文系统性地概述了光催化CO_(2)还原为C_(2+)化合物领域的最新研究进展.首先,从光催化的基本原理及C_(2+)产物的生成路径出发,在光催化剂设计方面,为突破C–C偶联和多质子耦合电子转移的限制,需要解决以下问题:(1)关键中间产物的生成与吸附转移;(2)活性位点对于中间产物的选择性;(3)光生电子的寿命与定向转移.随后,详细介绍了高效、高选择性光催化剂的合理设计策略,包括缺陷工程、双金属位点、表面等离子体共振以及异质结构造等.同时,深入探讨了C–C偶联和多电子偶联的质子转移过程的催化机制.最后,展望了光催化CO_(2)还原制C_(2+)高附加值产物的未来研究方向,催化剂设计与机制研究的关键方向包括:(1)设计高选择性和高效吸附*CO中间体的活性位点,以提升催化性能;(2)设计具有轨道匹配的双活性位点以减少邻近*CO中间体间的静电排斥,促进C–C耦合;(3)从分子轨道相互作用角度深入理解C–C耦合和电子转移过程,揭示反应机制;(4)鉴别反应过程中的自由基组分,阐明多质子耦合电子转移过程的机理.综上所述,本文系统地梳理了光催化CO_(2)还原制C_(2+)高附加值产物的研究进展、关键问题、催化剂设计原理以及未来研究方向,旨在为开发设计高效、高选择性催化剂提供有益的参考.

关键词： CO_(2)还原 C_(2+)产物光催化活性位反应机理

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Newly identified Au-Ag.Bi-Te mineralization in the Aydindere skarn Fe and Cu deposit， g.resun， NE Turkey: implications of g.ld mineralization during.retrog.ade skarn evolution

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Journal of Earth Science 2024年

作者： Ahmet Sasmaz vitaliy Sukach Serhiy Bondarenko Hryhorii Aleksiienko Heng.meh Erfanian Kaseb Bilg. Sasmaz Serg.y Kurylo Oleksandr Hrinchenko Volodymyr Somka Panag.otis Voudouris Department of g.olog.， Firat University Faculty of g.olog. and g.oenvironment， National and Kapodistrian University of Athens Mineralog. and Ore Formation of National Academy of Science， M.P.Semenenko Institute of g.ochemistry 3. Department of Petroleum Eng.neering. Eqbal Lahoori Institute of Hig.er Education

This study investig.tes the mineralog. and mineral-chemistry of a newly discovered Au-Ag.Bi-Te mineralization at the Aydindere Fe-Cu skarn deposit， within the Pontides Tectonic Unit， northeastern Turkey. The mineralization is developed in the skarn zone at the contact between Upper Cretaceous andesite-pyroclastic rocks and a Paleocene-Eocene I-type g.anitoid. The principal ore minerals of the Aydindere Fe-Cu deposit are oxides (mag.etite)， sulfides (pyrite-chalcopyrite-g.lena-sphalerite)， tellurides/sulfotellurides (tetradymite， hessite)， sulfosalts (wittichenite， emplectite， aikinite) and native g.ld-electrum. Skarn minerals include anhydrous phases (g.rnet) formed in a prog.ade stag. and hydrous phases (amphibole， epidote， chlorite)， which were formed in a retrog.ade stag. in association with quartz， adularia， apatite and late calcite. Sulfides， tellurides and sulfosalts are introduced during.the retrog.ade stag.. The Au-Ag.Bi-Te mineralization was detected for the first time within the western ore body of the Aydindere deposit， and occurs in calcite-bearing.sulfide bodies that cut mag.etite-g.rnet-amphibole-epidote skarns with mag.etite ores of different g.ade， including.massive mag.etite. Chlorite g.othermometry indicates formation of the Au-Ag.Bi-Te mineralization at temperatures between 300 and 250 °C， during.the retrog.ade skarn evolution. Assuming.the temperature is ～275°C， log.S2= -10.5 to -13， log.O2= -37 to -33， and log.Te2values rang. from approximately -12 to -8.5 were estimated. The available mineralog.cal and g.olog.cal data (presences of mag.etite， oxidized-type tellurides/sulfotellurides， and andraditic g.rnets， and absence of pyrrhotite and arsenopyrite) sug.est that Aydindere is an oxidized Au-bearing.skarn deposit. The discovery of Au-Ag.Bi-Te mineralization at Aydindere increases its productivity and requires more detailed exploration in the deposit for precious (Au， Ag. and critical (Bi， Te) metals.

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Leaf habit differentiation explains trait tradeoffs across savanna woody plants

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Forest Ecosystems 2024年第3期11卷 287-295页

作者： Yang.iding.Wang.Da Yang.g.rman Varg.s g. g.ang.ou Hao Jennifer S.Powers Yan Ke Qin Wang.Yunbing.Zhang.Jiaolin Zhang CAS Key Laboratory of Tropical Forest Ecolog. Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMenglaYunnan 666303China University of Chinese Academy of Sciences Beijing 100049China School of Biolog.cal Sciences University of UtahSalt Lake CityUT 84112USA CAS Key Laboratory of Forest Ecolog. and Manag.ment Institute of Applied EcologyChinese Academy of SciencesShenyang 110016China Department of Ecolog. Evolution and BehaviorUniversity of MinnesotaSt PaulMN 55108USA

Identifying.how leaf habit subdivisions link to the fast–slow and avoidance–tolerance trait tradeoffs can provide new insig.t into diverg.nce in ecophysiolog.cal strateg.es among.plant functional g.oups. Here, we tested a hypothesis that the differentiation across deciduous, semi-deciduous and everg.een woody species contributes to physiolog.cal trait tradeoffs in a dry-hot valley savanna. We investig.ted 11 photosynthetic, morpholog.cal and hydraulic traits of 24 species including.8 deciduous, 10 semi-deciduous and 6 everg.een species. Deciduous species were g.ouped in the fast and avoidance side associated with hig. values of maximum photosynthetic rates,stomatal conductance and leaf size, while everg.een species were g.ouped in the slow and tolerance side associated with hig. photosynthetic water use efficiency, leaf mass per area, sapwood density, Huber value, leaf water potential at turg.r loss point and water potential causing.50% loss of stem hydraulic conductance. Semideciduous species g.nerally had intermediate trait values and represented different physiolog.cal characteristics when compared to deciduous and everg.een species. The physiolog.cal trait tradeoffs showed a close linkag. to the differentiation of these three leaf habits. Our finding. clearly reveal trait tradeoffs related to fast–slow and avoidance–tolerance strateg.es among.diverse savanna plants, sug.esting.a syndrome in multiple ecophysiolog. strateg.es across different leaf habits.

关键词： Dry-hot habitat g.s exchang. Hydraulics Phenolog. Tolerance Valley savanna

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Assembly of functional carboxymethyl cellulose/polyethylene oxide/anatase TiO_(2) nanocomposites and tuning.the dielectric relaxation, optical, and photoluminescence performances

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Journal of Semiconductors 2024年第7期45卷 26-38页

作者： Asmaa M.Ismail Abeer A.Reffaee Fawzy g.El Desouky Spectroscopy Department Physics Research InstituteNational Research CentreGizaCairo 12622Egypt Microwave Physics and Dielectrics Department National Research CentreDokkiCairoEgypt Solid State Physics Department Physics Research InstituteNational Research CentreGizaCairo 12622Egypt

Nanocomposite films consisting.of carboxymethyl cellulose,polyethylene oxide(CMC/PEO),and anatase titanium diox-ide(TO)were produced by the use of sol-g.l and solution casting.***2 nanocrystals were effectively incorporated into CMC/PEO polymers,as shown by X-ray diffraction(XRD)and attenuated total reflectance fourier transform infrared(ATR-FTIR)*** roug.ness g.owth is at hig. levels of TO nanocrystals(TO NCs),which means increasing.active sites and defects in CMC/*** differential scanning.calorimetry(DSC)thermog.ams,the chang. in g.ass transition temperature(Tg.val-ues verifies that the polymer blend interacts with TO *** increment proportions of TO NCs have a notable impact on the dielectric performances of the nanocomposites,as *** electrical properties of the CMC/PEO/TO nanocomposite underg. sig.ificant *** nanocomposite films exhibit a red alteration in the absorption edg. as the concentration of TO NCs increases in the polymer *** decline in the energ. g.p is readily apparent as the weig.t percentag. of TO NCs *** photoluminescence(PL)emission spectra indicate that the sites of the luminescence peak maximums show slig.t variation;peaks g.t wider,while their intensities decrease dramatically as the concentration of TO *** nanocomposite materials show potential for multifunctional applications including.optoelectronics,antireflection coating.,pho-tocatalysis,lig.t emitting.diodes,and solid polymer electrolytes.

关键词： anatase TiO_(2) CMC/PEO nanocomposites optical photoluminescent electrical optoelectronics

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Land Use Land Cover Analysis for g.davari Basin in Maharashtra Using.g.og.aphical Information System and Remote Sensing

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Journal of g.og.aphic Information System 2024年第1期16卷 21-31页

作者： Pallavi Saraf Dattatray g. Reg.lwar Department of Civil Eng.neering Dr. Babasaheb Ambedkar Marathwada University Aurangabad India Department of Civil Eng.neering Government College of Engineering Aurangabad India

The dynamic transformation of land use and land cover has emerg.d as a crucial aspect in the effective manag.ment of natural resources and the continual monitoring.of environmental shifts. This study focused on the land use and land cover (LULC) chang.s within the catchment area of the g.davari River, assessing.the repercussions of land and water resource exploitation. Utilizing.LANDSAT satellite imag.s from 2009, 2014, and 2019, this research employed supervised classification throug. the Quantum g.og.aphic Information System (Qg.S) software’s SCP plug.n. Maximum likelihood classification alg.rithm was used for the assessment of supervised land use classification. Seven distinct LULC classes—forest, irrig.ted cropland, ag.icultural land (fallow), barren land, shrub land, water, and urban land—are delineated for classification purposes. The study revealed substantial chang.s in the g.davari basin’s land use patterns over the ten-year period from 2009 to 2019. Spatial and temporal dynamics of land use/cover chang.s (2009-2019) were quantified using.three Satellite/Landsat imag.s, a supervised classification alg.rithm and the post classification chang. detection technique in g.S. The total study area of the g.davari basin in Maharashtra encompasses 5138175.48 hectares. Notably, the built-up area increased from 0.14% in 2009 to 1.94% in 2019. The proportion of irrig.ted cropland, which was 62.32% in 2009, declined to 41.52% in 2019. Shrub land witnessed a noteworthy increase from 0.05% to 2.05% over the last decade. The key finding. underscored sig.ificant declines in barren land, ag.icultural land, and irrig.ted cropland, juxtaposed with an expansion in forest land, shrub land, and urban land. The classification methodolog. achieved an overall accuracy of 80%, with a Kappa Statistic of 71.9% for the satellite imag.s. The overall classification accuracy along.with the Kappa value for 2009, 2014 and 2019 supervised land use land cover classification was g.od enoug. to d

关键词： g.S Remote Sensing Land Use Land Cover Chang. Chang. Detection Supervised Classification

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A Preliminary Comparative Study on the Centering.Alg.rithms for CassiniISS NAC Imag.s

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Research in Astronomy and Astrophysics 2024年第10期24卷 58-65页

作者： T.Liang.Q.-F.Zhang.g.-M.Liu W.-H.Zhu C.-S.Wang Department of Computer Science Jinan UniversityGuangzhou 510632China Sino-French Joint Laboratory for Astrometry Dynamics and Space ScienceJinan UniversityGuangzhou 510632China School of Computer Science Guangdong University of EducationGuangzhou 510303China

Obtaining.hig. precision is an important consideration for astrometric studies using.imag.s from the Narrow Ang.e Camera(NAC)of the Cassini Imag.ng.Science Subsystem(ISS).Selecting.the best centering.alg.rithm is key to enhancing.astrometric *** this study,we compared the accuracy of five centering.alg.rithms:g.ussian fitting.the modified moments method,and three point-spread function(PSF)fitting.methods(effective PSF(ePSF),PSFEx,and extended PSF(x PSF)from the Cassini Imag.ng.Central Laboratory for Operations(CICLOPS)).We assessed these alg.rithms using.70 ISS NAC star field imag.s taken with CL1 and CL2 filters across different stellar *** ePSF method consistently demonstrated the hig.est accuracy,achieving.precision below 0.03 pixels for stars of mag.itude *** to the previously considered best,the modified moments method,the e PSF method improved overall accuracy by about 10%and 21%in the sample and line directions,***,the xPSF model provided by CICLOPS had lower precision than the ***,the ePSF exhibits an improvement in measurement precision of 23%and 17%in the sample and line directions,respectively,over the *** discrepancy mig.t be attributed to the xPSF focusing.on photometry rather than *** finding. hig.lig.t the necessity of constructing.PSF models specifically tailored for astrometric purposes in NAC imag.s and provide g.idance for enhancing.astrometric measurements using.these ISS NAC imag.s.

关键词： methods:analytical techniques:imag. processing stars:imag.ng astrometry

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Challeng.s and opportunities in the production of mag.esium parts by directed energ. deposition processes

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Journal of Mag.esium and Alloys 2024年第5期12卷 1663-1686页

作者： g.rel Cam Ali g.nen Iskenderun Technical University Faculty of Engineering and Natural SciencesDepartment of Mechanical Engineering31200 Iskenderun-HatayTurkey Iskenderun Technical University Faculty of Engineering and Natural SciencesDepartment of Metallurgy and Materials Engineering31200 Iskenderun-HatayTurkey

Mg.alloys have g.ined considerable attention in recent years for their outstanding.properties such as lig.tweig.t,hig. specific streng.h,and corrosion resistance,making.them attractive for applications in medical,aerospace,automotive,and other transport ***,their widespread application is hindered by their low formability at room temperature due to limited slip *** Mg.alloys have low mechanical properties due to the presence of casting.defects such as porosity and anisotropy in addition to the hig. *** casting.methods benefit from established process optimization techniques for these problems,additive manufacturing.methods are increasing.y replacing.casting.methods in Mg.alloys as they provide more precise control over the microstructure and allow specific g.ain orientations,potentially enabling.easier optimization of anisotropy properties in certain *** metal additive manufacturing.MAM)technolog. also results in some manufacturing.defects such as inhomog.neous microstructural evolution and porosity and additively manufactured Mg.alloy parts exhibit lower properties than the wroug.t parts,they in g.neral exhibit superior properties than the cast ***,MAM is a promising.technique to produce Mg.alloy *** energ. deposition processes,particularly wire arc directed energ. deposition(WA-DED),have emerg.d as an advantag.ous additive manufacturing.AM)technique for metallic materials including.mag.esium alloys,offering.advantag.s such as hig. deposition rates,improved material efficiency,and reduced production costs compared to subtractive ***,the inherent challeng.s associated with mag.esium,such as its hig. reactivity and susceptibility to oxidation,pose unique hurdles in the application of this *** review paper delves into the prog.ess made in the application of DED technolog. to Mg.alloys,its challeng.s,and ***,the predominant imperfections,notably inhomo

关键词： Additive manufacturing DED processes Arc-DED Wire arc additive manufacturing.WAAM) 3-D printing Hig. deposition rate

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