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Prolonged conjunctivitis mimicking nodular episcleritis as a manifestation of granulomatosis with polyangiitis-a case report

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Annals of Eye Science 2022年第1期7卷 114-118页

作者： Hong Nien Lee visvaraja subrayan Sultanah Fatimah Specialist Hospital JohorMalaysia University Malaya Specialist Center Kuala LumpurMalaysia

Red eye is common in our daily *** ranges from non-inflammatory to inflammatory *** extended course of disease should prompt suspicion and the possibility of diagnosis revision.A prolonged conjunctivitis mimicking nodular episcleritis can be presented as a manifestation of granulomatosis with polyangiitis(GPA).A 57-year-old woman complained of eye redness and tearing for two weeks which partially resolved with *** was subsequently commenced on topical and oral non-steroidal anti-inflammatory drugs(NSAIDs)and topical ***,in the following reviews she developed cornea thinning and her systemic examination revealed an injected uvula with absence of upper respiratory tract *** was investigated for connective tissue disease and found to have raised anti-inflammatory markers and her antinuclear antibody and C-ANCA tests were *** was diagnosed with *** conditions improved followed by the commencement of topical corticosteroid with high dose of systemic corticosteroid,which followed by a tapering regime with oral *** red eye is common,it is associated with a variety of *** manifestation can be as subtle as a red *** prolonged partially treated red eye should prompt suspicion of a more sinister *** detection of other subtle systemic signs is very important.

关键词： Granulomatosis with polyangiitis(GPA) episcleritis peripheral ulcerative keratitis(PUK) C-ANCA corticosteroid case report

疑似自然消退型视网膜母细胞瘤伴牵引型视网膜脱离和晶状体脱位1例(英文)

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国际眼科杂志 2009年第3期9卷 423-424页

作者： visvaraja subrayan Nadir Ali Mohamed Ali Dinesh Kumar Patel 马来亚大学医学院眼科马来西亚吉隆坡

我们报告了1例疑似盲眼中自然消退型视网膜母细胞瘤病例。肿瘤稳定,无眼外扩散长达20a。其他症状包括:带状角膜病变,白瞳,晶状体脱位,视网膜肿块钙化和牵引型视网膜脱离。

关键词：视网膜母细胞瘤钙化牵引型视网膜脱离

玻璃体切割术联合人工晶状体巩膜固定术治疗眼外伤的疗效(英文)

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国际眼科杂志 2012年第6期12卷 1016-1018页

作者： Angela V PLoo Sujaya Singh Mohammadreza Peyman visvaraja subrayan 马来西亚大学医学中心眼科马来西亚吉隆坡坡玛拉工艺大学眼科马来西亚吉隆

目的:探讨玻璃体切割术(pars plana vitrectomy,PPV)联合人工晶状体(intraocular lens,IOL)巩膜固定术治疗眼外伤的疗效。方法:系列病例回顾性分析。将马来西亚大学医学中心接受PPV联合IOL巩膜固定术的8例连续性病例纳入研究,其中1例患... 详细信息

目的:探讨玻璃体切割术(pars plana vitrectomy,PPV)联合人工晶状体(intraocular lens,IOL)巩膜固定术治疗眼外伤的疗效。方法:系列病例回顾性分析。将马来西亚大学医学中心接受PPV联合IOL巩膜固定术的8例连续性病例纳入研究,其中1例患者双眼均受伤,共有9眼。对现阶段视力,手术技巧,并发症及术后疗效进行分析。结果:9眼中有8眼(89%)视力提高。术后主要并发症是眼压升高,无缝线破裂。结论:PPV联合IOL巩膜固定术对有眼外伤病史的患者有非常好的疗效。

关键词：眼外伤玻璃体切割术人工晶状体巩膜固定术

玻璃体内注射曲安奈德治疗继发于IRVAN的黄斑水肿(英文)

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国际眼科杂志 2010年第11期10卷 2058-2059页

作者： Terrence Kwong-Weng Soong visvaraja subrayan Choo May May 马来亚大学眼科

目的:报告玻璃体内注射曲安奈德对特发性视网膜炎、血管炎、动脉瘤及视神经视网膜炎(IRVAN)所致的黄斑水肿的治疗效果。方法:病例报告。结果:患者诊断为特发性视网膜炎、血管炎、动脉瘤及视神经视网膜炎导致的伴有视力丧失的继发性黄斑... 详细信息

目的:报告玻璃体内注射曲安奈德对特发性视网膜炎、血管炎、动脉瘤及视神经视网膜炎(IRVAN)所致的黄斑水肿的治疗效果。方法:病例报告。结果:患者诊断为特发性视网膜炎、血管炎、动脉瘤及视神经视网膜炎导致的伴有视力丧失的继发性黄斑水肿。玻璃体内注射曲安奈德后黄斑水肿减轻,视力显著改善。结论:以前的报告建议采取全视网膜光凝,玻璃体切除术及全身和眼部类固醇治疗。对于继发于IRVAN的黄斑水肿和血管炎,玻璃体内注射曲安奈德是一种安全有效的治疗方法。

关键词： IRVAN 玻璃体内注射曲安奈德光学相干断层扫描黄斑水肿

黄斑色素光学密度、中央黄斑厚度与体重指数的关系（英文）

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国际眼科杂志 2019年第5期19卷 709-713页

作者： Lee Hong Nien Fazliana Ismail Rafidah Sudarno Angela Loo Voon Pei visvaraja subrayan 马来西亚大学医疗中心眼科马来西亚吉隆坡59100 Tunku Abdul Rahman大学医学部马来西亚吉隆坡蕉赖43000

目的:评估黄斑色素光学密度(MPOD)、中央黄斑厚度与体重指数(BMI)的关系。方法:这是一项在单一机构中进行比较的横断面研究。本研究共纳入210名符合入选标准的志愿者。使用黄斑色素筛选剂II对受试者MPOD进行测量。使用SD Cirrus OCT测... 详细信息

目的:评估黄斑色素光学密度(MPOD)、中央黄斑厚度与体重指数(BMI)的关系。方法:这是一项在单一机构中进行比较的横断面研究。本研究共纳入210名符合入选标准的志愿者。使用黄斑色素筛选剂II对受试者MPOD进行测量。使用SD Cirrus OCT测量中央黄斑厚度。记录所有眼MPOD和OCT信息。使用Microsoft~?Excel,SPSS和R进行数据分析。结果:MPOD和中央黄斑厚度之间呈明显正相关(r=0.42,P<0.01)。同时,MPOD和BMI之间呈明显负相关(r=-0.23,P<0.01)。结论:研究得出,MPOD和中央黄斑厚度之间呈明显正相关。还需要进一步研究中央凹的详细结构及其与MPOD的关系。研究发现了MPOD与BMI之间呈明显正相关,且得出BMI的降低可能会增加黄斑色素的密度,这有助于预防年龄相关性黄斑变性(ARMD)。

关键词：黄斑色素光学密度体重指数中央黄斑厚度

Vogt-Koyanagi-Harada disease in a 9-year-old girl

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Journal of Coastal Life Medicine 2015年第10期 838-839页

作者： Lott Pooi Wah Syed Shoeb Ahmad Shuaibah Abdul Ghani visvaraja A/L subrayan Ophthalmology Department University of MalayaJalan University50603Kuala LumpurWilayah Persekutuan Kuala LumpurMalaysia Ophthalmology Department Karung Berkunci No.2029Jalan PenampangKota Kinabalu88560Kota KinabaluSabahMalaysia

Uveitis secondary to Vogt-Koyanagi-Harada disease is rare in *** the best of our knowledge,this patient is the first reported case of uveitis attributed to VKH in a child in Malaysia.A 9-year-old girl complained of non-resolving painful red eyes bilaterally for 3 *** segment of right eye showed mutton fat keratic precipitates,posterior synechiae and moderate anterior chamber *** segment of left eye revealed mutton fat keratic precipitates,band keratopathy on peripheral 3 and 9 o'clock of the cornea,iris bombe,iris nodule and seclusio *** examination of right eye revealed subretinal deposit at superior and inferior arcades with flat retina while left eye showed hazy *** was then noted to have poliosis and vitiligo after 1 month from initial *** cataract and widespread atrophy of the retinal pigment epithelium accounting for the loss in vision *** case report is to highlight the importance of early recognition of paediatric Vogt-Koyanagi-Harada and treating it aggressively to prevent the irreversible destructive sequalae of the disease.

关键词： Vogt-Koyanagi-Harada disease Seclusion pupillae Vitiligo Poliosis

免疫功能正常患者鼻眶部毛霉菌病的研究(英文)

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国际眼科杂志 2012年第4期12卷 609-611页

作者： Keat Ween Khaw Amir bin Samsudin Zurina ZA Mimiwati binti Zahari visvaraja subrayan 马来亚大学医学中心眼科

报告1例免疫功能正常患者鼻眶部毛霉菌病非典型病例,并对该病例进行相关文献回顾。患者,男,17岁,免疫功能正常,左眼2mo缓慢进行性疼痛肿胀。行组织活检,病理学诊断为毛霉菌病。采用综合疗法,包括筛窦及上颌窦侵入性内窥镜切除和清创、... 详细信息

报告1例免疫功能正常患者鼻眶部毛霉菌病非典型病例,并对该病例进行相关文献回顾。患者,男,17岁,免疫功能正常,左眼2mo缓慢进行性疼痛肿胀。行组织活检,病理学诊断为毛霉菌病。采用综合疗法,包括筛窦及上颌窦侵入性内窥镜切除和清创、左眼眶内容物刮除术、静脉注射两性霉素B和眶内两性霉素B冲洗,成功根除真菌感染。该病例说明,鼻眶部毛霉菌病可发生在年轻健康的个体身上。早期诊断,积极的药物和手术治疗对成功地治疗这种罕见的具有潜在致命性的疾病是至关重要的。

关键词：鼻眶部毛霉菌病免疫功能正常内容物刮除术两性霉素B

A giant traumatic iris cyst

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Journal of Coastal Life Medicine 2015年第12期 1006-1007页

作者： Lott Pooi Wah Tan Boon Hooi Leow Sue Ngein Shuaibah Abdul Ghani visvaraja A/L subrayan Ophthalmology Department University of MalayaJalan University50603Kuala LumpurWilayah PersekutuanMalaysia Ophthalmology Department Karung Berkunci No.2029Jalan PenampangKota Kinabalu88560Kota KinabaluSabahMalaysia

A 52 year-old construction worker presented with progressive painful blurring of vision in the left eye associated with redness for past 1 *** was a history of penetrating injury in the same eye 10 years ago and he underwent primary wound toilet and suturing,lens removal with intraocular lens *** lamp examination revealed a corneal scar at 9’oclock,a large transilluminant iris cyst superotemporally and adherent to corneal *** was extended from angle of the pupil and obstructing the visual *** patient underwent excision of an iris cyst through superior limbal *** was done to separate the cyst from the corneal endothelium and underlying iris *** blue ophthalmic solution was injected into the cyst to stain the cyst *** operatively 7 days,vision improved to 6/7.5 without *** was no recurrence up to 1 year *** finding revealed a benign cyst mass lined by simple cuboidal to nonkeratinized stratified squamous *** had achieved a good surgical outcome with no complication to date for our case *** advocate this modified surgical method to completely remove iris cyst.

关键词： Giant traumatic epithelial iris cyst Penetrating trauma Angle of the pupil Visual axis Viscodissection Cystectomy Trypan blue

Bee sting keratopathy with retained stinger

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Journal of Coastal Life Medicine 2016年第1期 83-84页

作者： Lott Pooi Wah Syed Shoeb Ahmad Yew Yih Voon Shuaibah Abdul Ghani visvaraja A/L subrayan Ophthalmology Department University of MalayaJalan University50603Kuala LumpurWilayah PersekutuanKuala LumpurMalaysia Ophthalmology Department Queen Elizabeth HospitalKarung Berkunci No.2029Jalan PenampangKota Kinabalu88560Kota KinabaluSabahMalaysia

This case report aims to report an uncommon case of bee sting keratopathy with retained stinger.A 55-year-old man presented with left cornea bee sting while gardening two days prior to first *** complained of severe eye pain with redness,tearing and blurring of *** examination,his right eye visual acuity was 6/6 and in left eye was hand *** was generalized conjunctival hyperemia and cornea showing significant descemet striae.A bee stinger with surrounding infiltration noted at 2 o'clock was associated with striate *** was deeply seated at the posterior third of cornea stroma near to paracentral *** was mid-dilated with absence of relative afferent pupillary *** was neither hypopyon nor *** posterior segment could not be visualized due to severe corneal ***,B-scan ultrasound was *** stinger was removed under local anaesthesia on the day of ***-operatively,patient was administered with topical moxifloxacin and topical non steroidal anti-inflammatory *** weeks later,there was resolution of cornea infiltrate with improvement of striate keratitis and his vision was improved to 1/***,cornea edema did not regress but ended up with bullous *** patient has undergone descemet-stripping automated endothelial keratoplasty and his vision was improved to 6/*** recommend early stinger removal to reduce the possible sequelae of bee sting toxicity for better visual outcome.

关键词： Striate keratitis Corneal wasp sting keratopathy Stinger Venom Bullous keratopathy