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Development of metal organic fromwork-199 immobilized zeolite foam for adsorption of common indoor VOCs

Journal of Environmental Sciences 2017年第5期29卷 321-330页

作者： vipin k.saini Joao Pires School of Environment and Natural Resources Doon UniversityDehradun 248001India Department of Chemistry and Biochemistry Faculty of SciencesUniversity of LisbonLisbon 1749-016Portugal

Reticulated foam shaped adsorbents are more efficient for the removal of volatile organic compounds（VOCs）,particularly from low VOC-concentration indoor air streams. In this study composite structure of zeolite and metal organic frameworks（MOFs）,referred as ZMF,has been fabricated by immobilization of fine MOF-199 powder on foam shaped Zeolite Socony Mobil-5（ZSM-5）Zeolitic structure,referred as ZF. The ZMF possess a uniform and well-dispersed coating of MOF-199 on the porous framework of ZF. It shows higher surface area,pore volume,and VOCs adsorption capacity,as compared to ***-fabrication changes in selective adsorption properties of ZMF were studied with three common indoor VOCs（benzene,n-hexane,and cyclohexane）,using gravimetric adsorption technique. The adsorption capacity of ZMF with different VOCs follow the order of benzene 〉 n-hexane 〉 cyclohexane. In comparison with MOF-199 and ZF,the composite structure ZMF shows improvement in selectivity for benzene from other two VOCs. Further,improvement in efficiency and stability of prepared ZMF was found to be associated with its high MOF loading capacity and unique morphological and structural properties. The developed composite structure with improved VOCs removal and recyclability could be a promising material for small to limited scale air pollution treatment units.

关键词： VOCs Adsorption Composite materials Selectivity Zeolite foam MOFs HkUST-1

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miR-153 as biomarker for cancer-functional role as tumor suppressor

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BIOCELL 2022年第1期46卷 13-26页

作者： SALONI THAkUR ADESH k.saini JOYDEEP DAS vipin saini PARIN BALHARA JAGPREET S.NANDA REENA V.saini Faculty of Applied Sciences and Biotechnology Shoolini UniversitySolan173229India Department of Biotechnology MMECMaharishi Markandeshwar(Deemed to be University)Mullana133207India Maharishi Markandeshwar University KumarhattiSolan173229India Department of Chemistry Physical SciencesMizoram UniversityAizawl796004India Department of kinesiology California State UniversitySacramentoCA 95819USA Laboratory on the Mechanism and Regulation of Protein Synthesis Eunice K.ShriverNational Institute of Child Health and Human DevelopmentNational Institutes of HealthBethesdaMD 20892USA

MicroRNA-153(miR-153),belongs toa dass of small non-coding *** is a aritical regulator of gene expression at the post-transcriptional lewel which interacts with the functional mRNA at 3UTR rgion and suppresses the expression of the *** recently,it has become apparent that dhanges in the miR-153 axpression lead to invasion,metastasis,angiogenesis and various types of tumor *** review summarizes the connection between dysrgulation of miR-153 and various typas of cancer ***-153 regulates various signaling pathways to inhibit the proliferation and induce apoptosis in the ancer cell and also show synergistic activity with anticancer *** addition to this,the oncogenic bchavior of miR-153 and their use as a potential biomarker in cancer was also reviewed.

关键词： Biomarker Cancer miR-153 Oncogenic Tumor suppressor

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Implant biomaterials: A comprehensive review

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World Journal of Clinical Cases 2015年第1期3卷 52-57页

作者： Monika saini Yashpal Singh Pooja Arora vipin Arora krati Jain Department of Oral and Maxillofacial Rehabiliatation Al Qaseem Pvt.CollegesBuraydahQassim 51431Saudi Arabia Department of Prosthodontics Subharati Dental College Meerut 250003India Department of Operative Dentistry and Endodontics Subharati Dental College Meerut 250003 India

Appropriate selection of the implant biomaterial is a key factor for long term success of implants. The biologic environment does not accept completely any material so to optimize biologic performance, implants should be selected to reduce the negative biologic response while maintaining adequate function. Every clinician should always gain a thorough knowledge about thedifferent biomaterials used for the dental implants. This article makes an effort to summarize various dental biomaterials which were used in the past and as well as the latest material used now.

关键词： Biomaterials Zirconium Surface roughness Ceramic Corrosion

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Simultaneous Determination of Verapamil Hydrochloride and Gliclazide in Synthetic Binary Mixture and Combined Tablet Preparation by Chemometric-Assisted Spectroscopy

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Journal of Analytical Sciences, Methods and Instrumentation 2012年第3期2卷 161-166页

作者： Rahul Bhaskar Radhika Bhaskar Mahendra k. Sagar vipin saini krishnamoorthy Bhat Department of Pharma Quality Assurance Manipal College of Pharmaceutical Sciences Manipal University Manipal India Department of Pharmacy Mahatma Jyoti Rao Phoole University Jaipur India

In this study, the simultaneous determination of verapamil hydrochloride and gliclazide in pharmaceuticals by chemometric approaches using UV spectrophotometry has been reported. Verapamil hydrochloride (VER) (Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl) ethyl] methylamino]propyl]-3, 4-dimethoxy-α-(1-methylethyl) hydrochloride) is an L-type calcium channel blocker of the phenylalkylamine class. It has been used in the treatment of hypertension, angina pectoris, and cardiac arrhythmia. Gliclazide (GLZ) (1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-[(4-methylphenyl) sulphonyl]urea) is an oral hypoglycaemic (anti-diabetic) drug and is classified as a second generation sulfonylurea. Spectra of VER and GLZ were recorded at several concentrations within their linear ranges between wavelengths of 200 nm to 400 nm in 0.1N HCl. Partial least squares regression (PLS) and principle components regression (PCR) were used for chemometric analysis of data and the parameters of the chemometric procedures were optimized. The recoveries were satisfactory and statistically comparable. The method was successfully applied to pharmaceutical formulation, tablet, with no interference from excipients as indicated by the recovery study results. The proposed methods are simple, rapid and can be easily used in the quality control of drugs as alternative analysis tools.

关键词： Partial Least-Squares Principle Components Regression Spectroscopy Verapamil Hydrochloride Gliclazide

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