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Barringtonia acutangula improves the biochemical parameters in diabetic rats

Chinese Journal of Natural Medicines 2014年第2期12卷 126-130页

作者： Marslin Gregory vinoth Kumar Megraj Khandelwal Revina Ann Mary V.K.Kalaichelvan V.Palanivel Department of Pharmacology Faculty of Pharmacy Annamalai University Centre for the Research and Technology of Agro-Environment and Biological Sciences (CITAB) Department of Biology University of Minho Consorzio Mario Negri Sud Department of Translational Pharmacology Department of Nursing Science A.J. College of Nursing Padmavathi College of Pharmacy and Research Institute

AIM: This study was aimed at evaluating the anti-diabetic activity of the ethanol and aqueous extracts of the leaf material of Barringtonia acutangula in a diabetic animal model. METHODS: The ethanolic and aqueous extracts(250 and 500 mg kg 1body weight) of the leaves of B. acutangula were assessed for antidiabetic activity in a streptozotocin(STZ)-induced diabetes animal model following 21 days of treatment. Glibenclamide(0.6 mg kg 1p.o.) was used as a positive control. The hematological parameters, such as blood glucose level, urea, creatinin, cholesterol, HDL-C, and LDL-C levels were examined. RESULTS: An acute toxicity study(5 000 mg kg 1, p.o.) did not produce any symptoms of toxicity. Significant reductions in blood glucose level, and serum total cholesterol and triglyceride levels were noted in animals treated with the extract. The high density lipoprotein-cholesterol(HDLC) level was found to increase as compared with the diabetic control group. CONCLUSION: These results suggest that the leaf aqueous and ethanolic extracts of B. acutangula have anti-diabetic effects. The aqueous extract of B. acutangula produced a similar effect when compared with the ethanol extract. It is proposed that consumption of B. acutangula in some form like tea may help the management of diabetes.

关键词： Barringtonia acutangula Ethanolic extract Aqueous extract Anti-diabetic activity

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Industrial Centric Node Localization and Pollution Prediction Using Hybrid Swarm Techniques

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Computer Systems Science & Engineering 2022年第8期42卷 545-560页

作者： R.Saravana Ram M.vinoth Kumar N.Krishnamoorthy A.Baseera D.Mansoor Hussain N.Susila Department of Electronics and Communication Engineering Anna UniversityUniversity College of Engineering DindigulDindigul624622India Department of Computer Science and Engineering Anna UniversityUniversity College of Engineering DindigulDindigul624622India Department of Computer Science and Engineering Kongu Engineering CollegePerundurai638060India School of Computing Science and Engineering VIT Bhopal UniversityBhopal466114India Department of Computer Science and Engineering Sri Krishna College of Engineering and TechnologyCoimbatore641008India Department of Information Technology Sri Krishna College of Engineering and TechnologyCoimbatore641008India

Major fields such as military applications,medical fields,weather forecasting,and environmental applications use wireless sensor networks for major computing *** play a vital role in emerging technologies of the 20th *** of sensors in needed locations is a very serious *** environment is home to every living being in the *** growth of industries after the industrial revolution increased pollution across the *** to recent uncontrolled growth and development,sensors to measure pollution levels across industries and surroundings are *** interesting and challenging task is choosing the place to fit the *** meta-heuristic techniques have been introduced in node *** intelligent algorithms have proven their efficiency in many studies on localization *** this article,we introduce an industrial-centric approach to solve the problem of node localization in the sensor ***,our work aims at selecting industrial areas in the sensed *** use random forest regression methodology to select the polluted ***,the elephant herding algorithm is used in sensor node *** two algorithms are combined to produce the best standard result in localizing the sensor *** check the proposed performance,experiments are conducted with data from the KDD Cup 2018,which contain the name of 35 stations with concentrations of air pollutants such as PM,SO_(2),CO,NO_(2),and O_(3).These data are normalized and tested with *** results are comparatively analyzed with other swarm intelligence algorithms such as the elephant herding algorithm,particle swarm optimization,and machine learning algorithms such as decision tree regression and multi-layer *** can indicate our proposed algorithm can suggest more meaningful locations for localizing the sensors in the *** proposed method achieves a lower root mean square value with 0.06 to 0.08 for lo

关键词： Wireless sensor networks node localization industrial-centric approach random forest regression elephant herding optimization swarm intelligence pollution

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Antimicrobial potential of Actinomycetes species isolated from marine environment

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Asian Pacific Journal of Tropical Biomedicine 2012年第6期2卷 469-473页

作者： Valli S Suvathi Sugasini S Aysha OS Nirmala P vinoth Kumar P Reena A PG and Research Department of Microbiology Mohamed Sathak College of Arts & Science

Objective:To evaluate the antimicrobial activity of Actinomycetes species isolated from marine ***:Twenty one strains of Actinomyceteswere isolated from samples of Royapuram, Muttukadu, Mahabalipuram sea shores and Adyar estuary. Preliminary screening was done using cross-streak method against two gram-positive and eight gram-negative *** most potent strains C11 and C12 were selected from which antibacterial substances were extracted. The antibacterial activities of the extracts were performed using Kirby-Bauer disc diffusion method. Molecular identification of those isolates was ***:All those twenty one isolates were active against at least one of the test organisms. Morphological characters were recorded. C11 showed activity againstStaphylococcusspecies(13.0暲0.5 mm),Vibrio harveyi(11.0暲0.2 mm),Pseudomonas species(12.0暲0.3 mm). C12 showed activity against Staphylococcus species(16.0暲0.4 mm),Bacillus subtilis(11.0暲0.2 mm),Vibrio harveyi(9.0暲0.1 mm),Pseudomonas species(10.0暲0.2 mm). 16S rRNA pattern strongly suggested that C11 and C12 strains were Streptomyces ***:The results of the present investigation reveal that the marineActinomycetesfrom coastal environment are the potent source of novel ***, characterization and study of Actinom ycetescan be useful in discovery of novel species of Actinomy cetes.

关键词： MarineActinomycetes Antimicrobial activity Streptomyces 16S rRNA Cross-streak method Antibacterial substance Kirby-Bauer disc diffusion method Molecular identification Morphological character

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Deep Fake Detection Using Computer Vision-Based Deep Neural Network with Pairwise Learning

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Intelligent Automation & Soft Computing 2023年第2期35卷 2449-2462页

作者： R.Saravana Ram M.vinoth Kumar Tareq M.Al-shami Mehedi Masud Hanan Aljuaid Mohamed Abouhawwash Department of Electronics and Communication Engineering Anna UniversityUniversity College of EngineeringDindigul624622India Department of Computer Science and Engineering Anna UniversityUniversity College of EngineeringDindigul624622India Department of Mathematics Faculty of ScienceSana’a UniversitySana’a 13509Yemen Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Computer Sciences Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman University(PNU)Riyadh11671Saudi Arabia Department of Mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational Mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA

Deep learning-based approaches are applied successfully in manyﬁelds such as deepFake identiﬁcation,big data analysis,voice recognition,and image *** is the combination of deep learning in fake creation,which states creating a fake image or video with the help of artiﬁcial intelligence for political abuse,spreading false information,and *** artiﬁcial intel-ligence technique has a wide demand,increasing the problems related to privacy,security,and *** paper has analyzed the features related to the computer vision of digital content to determine its *** method has checked the computer vision features of the image frames using the fuzzy clustering feature extraction *** the proposed deep belief network with loss handling,the manipulation of video/image is found by means of a pairwise learning *** proposed approach has improved the accuracy of the detection rate by 98%on various datasets.

关键词： Deep fake deep belief network fuzzy clustering feature extraction pairwise learning

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Enhanced Long Short Term Memory for Early Alzheimer's Disease Prediction

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Intelligent Automation & Soft Computing 2023年第2期35卷 1277-1293页

作者： M.vinoth Kumar M.Prakash M.Naresh Kumar H.Abdul Shabeer Department of Information Science and Engineering Dayananda Sagar Academy of Technology&ManagementKanakapura Main Road560082BangaloreIndia Department of Data Science and Business Systems School of Computing SRM Institute of Science and TechnologyKattankulathurChengalpattu603203TamilnaduIndia Department of ECE Vardhaman College of EngineeringHyderabad501218India IBM India Pvt Ltd. DLF IT ParkChennai600125India

The most noteworthy neurodegenerative disorder nationwide is appar-ently the Alzheimer's disease(AD)which ha no proven viable treatment till date and despite the clinical trials showing the potential of preclinical therapy,a sen-sitive method for evaluating the AD has to be developed *** to the correla-tions between ocular and brain tissue,the eye(retinal blood vessels)has been investigated for predicting the ***,en enhanced method named Enhanced Long Short Term Memory(E-LSTM)has been proposed in this work which aims atﬁnding the severity of AD from ocular ***ﬁnd the level of disease severity,the new layer named precise layer was introduced in E-LSTM which will help the doctors to provide the apt treatments for the patients *** avoid the problem of overﬁtting,a dropout has been added to *** the existing work,boundary detection of retinal layers was found to be inaccurate during the seg-mentation process of Optical Coherence Tomography(OCT)image and to over-come this issue;Particle Swarm Optimization(PSO)has been *** the best of our understanding,this is theﬁrst paper to use Particle Swarm *** compared with the existing works,the proposed work is found to be per-forming better in terms of F1 Score,Precision,Recall,training loss,and segmen-tation accuracy and it is found that the prediction accuracy was increased to 10%higher than the existing systems.

关键词： Alzheimer's disease enhanced LSTM particle swarm optimization OCT image boundary detection

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Soft Computing: Fuzzy Logic Approach in Wireless Sensors Networks

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Circuits and Systems 2016年第8期7卷 1242-1249页

作者： M. vinoth Kumar Dr. T. Lalitha Department of Computer Science and Engineering AVS Engineering College Salem India Sona College of Technology Salem India

The recent growth of communication and sensor technology results in the enlargement of a new attractive and challenging area-wireless sensor networks (WSNs). A network comprising of several minute wireless sensor nodes which are organized in a dense manner is called as a Wireless Sensor Network (WSN). Every node estimates the state of its surroundings in this network. The estimated results are then converted into the signal form in order to determine the features related to this technique after the processing of the signals. It’s high computational environment with limited and controlled broadcast range, processing, as well as limited energy. The embedded soft computing approach in wireless sensor networks is suggested. This approach means a grouping of embedded fuzzy logic and neural networks models for information processing in complex environment with unsure, rough, fuzzy measuring data. It is generalization of soft computing concept for the embedded, distributed, adaptive systems.

关键词： Embedded Fuzzy Logic Data Fusion Clusterization Aggregation Fuzzy Distributed Knowledge Base Sensor

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Superiorly based perforator plus fl ap for inguinal defects

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Plastic and Aesthetic Research 2014年第1期1卷 89-93页

作者： Pradeoth Mukundan Korambayil Prashanth Varkey Ambookan vinoth Kumar Dilliraj Department of Plastic Surgery and Burns Jubilee Institute of Surgery for HandAesthetic and MicrosurgeryJubilee Mission Medical College and Research InstituteThrissur 680005KeralaIndia

Aim:Inguinal block dissections for metastasis to inguinal lymph nodes and occasionally trauma are always associated with soft tissue loss over the groin region.A clinical study was undertaken to demonstrate the ability to utilize a superiorly-based perforatorﬂap with reliable vascularity and less donor site morbidity to cover defects in the inguinal ***:A prospective study was performed on 7 patients with inguinal soft tissue defects managed in our institution from January 2013 to September *** the study period,a“superiorly-based perforator plusﬂap”was used for soft tissue coverage over the femoral vessels in the inguinal *** oxygen therapy was administered *** postoperative period,hospital course,and follow-up after radiotherapy was documented in patients with inguinal block ***:Seven patients presented with soft tissue defects in the inguinal *** of the defects were secondary to prior surgery,and 2 were secondary to trauma.A superiorly-based perforator plusﬂap was performed in all *** defect sizes ranged from 9 cm×4 cm to 17 cm×8 ***ﬂap dimensions ranged from 12 cm×5 cm to 20 cm×10 *** secondary procedures were necessary following ***,there was no evidence of partial or totalﬂap ***ﬂap revisions were required,and no complications were experienced at either the donor or recipient site following *** were followed-up for 10-18 ***:Inguinal defects require stable soft tissue coverage to withstand radiotherapy following inguinal block dissection surgery,and are susceptible to wound *** superiorly-based perforator plusﬂap technique is simple,requires little operative time,and is a reliableﬂap for coverage of the femoral vessels and inguinal region with improved tolerance to postoperative radiotherapy.

关键词： Hyperbaric oxygen therapy inguinal lymph nodes soft tissue defect superiorly-based perforator plus flap

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Soft tissue defects of eyelid and malar region:an experience with the McGregor flap

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Plastic and Aesthetic Research 2015年第1期2卷 69-72页

作者： Pradeoth Korambayil Mukundan Prashanth Varkey Ambookan vinoth Kumar Dilliraj Jubilee Institute for Surgery of Hand Aesthetic and MicrosurgeryJubilee Mission Medical College and Research InstituteThrissur 680005KeralaIndia Department of Plastic Surgery and Burns Vijaya HospitalVadapalaniChennai 600026Tamil NaduIndia

Aim:Reconstruction of defects of the eyelids and malar region following trauma may result in considerable distortion of the adjacent tissue.A clinical study was undertaken to demonstrate the ability to utilize a modified McGregor flap for reliable soft tissue ***:Nine patients with eyelids and malar soft tissue defects were treated over a period of 12 months from July 2013 to June *** this prospective study,a McGregor flap was used for the closure of defects in 9 patients(7 men and 2 women),aged 20-36 years(mean age:27 years).Three sessions of hyperbaric oxygen therapy were administered postoperatively,and patients received subsequent ***:Six patients presented with malar and lower eyelid defects,2 patients presented with malar defects,and one patient with upper eyelid,lower eyelid and malar defects following trauma.A McGregor flap was performed in all *** preexcision defects varied in size from 3 cm×2 cm to 4 cm×3 *** secondary procedures were required in any *** were removed between 7 and 9 days *** were no cases of partial or total flap loss over the course of 10-14 months ***:The outcome following use of the McGregor flap procedure was functionally and aesthetically satisfactory in all *** McGregor flap is a useful option for the reconstruction of defects following trauma to the upper eyelid,lower eyelid,and malar regions.

关键词： Eyelid defects hyperbaric oxygen therapy malar defects McGregor flap

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Options for thumb revascularization: our experience and literature review

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Plastic and Aesthetic Research 2014年第1期1卷 37-40页

Traumatic injuries to the thumb resulting in segmental loss of a digital artery are not *** bridge the gap and repair a transacted digital artery,the superficial palmar arch or the radial digital artery of the index finger can be used to reconstruct the ulnar digital artery of thumb for *** following segmental loss resulting from a crushed ulnar digital artery of the thumb can be performed based on the superficial palmar arch or the radial digital artery of the index finger,avoiding anastomosis at two sites and hence providing better *** digital vein from the index finger can also be used to enhance the venous return of the injured ***,because of known variability in the palmar arch,intraoperative verification is needed to ensure the safe transfer of the arch or the radial digital artery of the index *** aim of this article is to discuss the possibilities for thumb revascularization,using a case report in which the injured thumb was revascularized with a superficial palmar arch.

关键词： Radial digital artery index finger superficial palmar arch thumb revascularization ulnar digital artery thumb

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Peno-scrotal soft tissue loss:a need for multidisciplinary and multimodal integration

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Plastic and Aesthetic Research 2016年第1期3卷 273-278页

作者： Pradeoth Korambayil Mukundan Prashanth Varkey Ambookan Ragu Angappan vinoth Kumar Dilliraj Department of Plastic Surgery and Burns Bahrain Defence Force Royal Medical ServicesEast Riffa 38285Bahrain

Aim:Scrotal soft tissue loss is a part of the challenging conditions for plastic *** non-availability of adequate nearby healthy soft tissue and its probability of frequent contamination by excretory substances make the issue of reconstruction *** authors present their experience with penoscrotal soft tissue loss with hyperbaric oxygen therapy as an ***:This retrospective study was undertaken in the department of plastic surgery,over a period of 2 *** patients with scrotal or penile injury and infection were enrolled in the *** of the patients ranged 20-60 *** patients had traumatic loss of scrotal skin and 4 resulted following necrotizing soft tissue *** patients underwent hyperbaric oxygen therapy before and following ***:Healing was complete in all patients with minor complications as partial skin graft loss in 2 *** patients(55.5%)had sustained the soft tissue loss due to *** cause of necrotizing fasciitis was found in 4 patients(44.4%).The mean length of hospital stay was 42.5 ***:Management of soft tissue loss of penoscrotal region requires an organized approach and the utilization of newer modalities for early recovery of these injuries is of primary *** surgeons should know the various reconstructive pathways and use of adjunct measures like hyperbaric therapy for early recovery.

关键词： Scrotal soft tissue loss necrotizing fasciitis soft tissue reconstruction hyperbaric oxygen therapy

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