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Recent advances and innovations in the design and fabrication of wearable flexible biosensors and human health monitoring systems based on conjugated polymers

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Bio-Design and Manufacturing 2024年第4期7卷 476-516页

作者： vinh van tran Viet-Duc Phung Daeho Lee Department of Mechanical Engineering Gachon UniversitySeongnam 13120Republic of Korea Institute of Fundamental and Applied Sciences Duy Tan UniversityHo Chi Minh City 700000Vietnam Faculty of Environmental and Chemical Engineering Duy Tan UniversityDa Nang 550000Vietnam

Wearable biosensors have received great interest as patient-friendly diagnostic technologies because of their high flexibility and *** growing research and utilization of novel materials in designing wearable biosensors have accelerated the development of point-of-care sensing platforms and implantable biomedical devices in human health *** numerous potential materials,conjugated polymers(CPs)are emerging as ideal choices for constructing high-performance wearable biosensors because of their outstanding conductive and mechanical ***,CPs have been extensively incorporated into various wearable biosensors to monitor a range of target ***,fabricating highly reliable CP-based wearable biosensors for practical applications remains a significant challenge,necessitating novel developmental strategies for enhancing the viability of such ***,this review aims to provide consolidated scientific evidence by summarizing and evaluating recent studies focused on designing and fabricating CP-based wearable biosensors,thereby facilitating future *** the superior properties and benefits of CPs,this review aims to clarify their potential applicability within this ***,the fundamentals and main components of CP-based wearable biosensors and their sensing mechanisms are discussed in *** recent advancements in CP nanostructures and hybridizations for improved sensing performance,along with recent innovations in next-generation wearable biosensors are *** wearable biosensors have been—and will continue to be—an ideal platform for developing effective and user-friendly diagnostic technologies for human health monitoring.

关键词： Conjugated polymers Wearable biosensors E-skin electronics Implantable biosensors Conductive polymer hydrogels

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Prediction of acute stroke progression by the National Institutes of Health Stroke Scale

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Journal of Geriatric Cardiology 2007年第4期4卷 225-228页

作者： vinh Phuong tran van Huy Department of Geriatric Cardiology Khanh Hoa HospitalVietnam

Objective To determine the occurrence of neurological changes during the first 48 hours after acute stroke as it relates to the initial stroke severity assessment. Methods The assessment with the National Institutes of Health Stroke Scale (NIHSS) was performed serially for the first 48 hours on 68 consecutive ischemic stroke patients admitted to the Department of Geriatric Cardiology at the Khanh Hoa Hospital, Nha trang, Vietnam. Incidence of stroke progression (a ≥ 3-point increase on the NIHSS) was recorded and analysis performed to determine its association with initial stroke severity and other demographic and physiological variables. Deficit resolution by 48 hours, defined as an NIHSS score of 0 or 1, measured the frequency of functional recovery predicted by the initial deficit. Results Overall progression was noted in 28% of events (19/68). Applying Bayes' solution to the observed frequency of worsening, the greatest likelihood of predicting future patient progression occurred with NIHSS score of =7 and >7. Patients with an initial NIHSS score of =7 experienced a 13% (6/47) worsening rate versus those of an initial score of >7 with a 62% (13/21) worsening rate (P7 returned to a normal examination within this period (χ2, P<0.05). Conclusions This study suggests that the early clinical course of neurological deficit after acute stroke be dependent on the initial stroke severity and that a dichotomy in early outcome exist surrounding an initial NIHSS score of 7. These findings may have significant implications for the design and patient stratification in treatment protocols with respect to primary clinical outcome.(J Geriatr Cardiol 2007;4:225-228.)

关键词： stroke prediction

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Development of a PARCS/Serpent model for neutronics analysis of the Dalat nuclear research reactor

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Nuclear Science and Techniques 2021年第2期32卷 32-44页

作者： Viet-Phu tran Kien-Cuong Nguyen Donny Hartanto Hoai-Nam tran vinh Thanh tran van-Khanh Hoang Pham Nhu Viet Ha Institute for Nuclear Science and Technology(INST) Vietnam Atomic Energy Institute(VINATOM)179 Hoang Quoc Viet str.Cau Giay DistrictHanoi 100000Vietnam Nuclear Research Institute(NRI) Vietnam Atomic Energy Institute(VINATOM)01 Nguyen Tu LucDalatLamdong 670000Vietnam Department of Mechanical and Nuclear Engineering University of SharjahPO.BOX 27272SharjahUnited Arab Emirates Institute of Fundamental and Applied Sciences Duy Tan UniversityHo Chi Minh city 700000Vietnam Faculty of Natural Science Duy Tan UniversityDanang 550000Vietnam Nuclear Safety Division Technical Support Center for Radiation and Nuclear Safety and Emergency ResponseVietnam Agency for Radiation and Nuclear Safety(VARANS)113 Tran Duy Hung str.Cau Giay DistrictHanoi 100000Vietnam

Cross-sectional homogenization for full-core calculations of small and complex reactor configurations,such as research reactors,has been recently recognized as an interesting and challenging *** paper presents the development of a PARCS/Serpent model for the neutronics analysis of a research reactor type TRIGA Mark-II loaded with Russian VVR-M2 fuel(known as the Dalat Nuclear Research Reactor or DNRR).The full-scale DNRR model and a supercell model for a shim/safety rod and its surrounding fuel bundles with the Monte Carlo code Serpent 2 were proposed to generate homogenized fewgroup cross sections for full-core diffusion calculations with *** full-scale DNRR model with Serpent 2 was also utilized as a reference to verify the PARCS/Serpent *** of the effective neutron multiplication factors,radial and axial core power distributions,and control rod worths showed a generally good agreement between PARCS and Serpent *** addition,the discrepancies between the PARCS and Serpent 2 results are also ***,the results indicate the applicability of the PARCS/Serpent model for further steady state and transient analyses of the DNRR.

关键词： PARCS Serpent 2 Group constant DNRR

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Finite element analysis of functionally graded sandwich plates with porosity via a new hyperbolic shear deformation theory

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Defence Technology（防务技术） 2022年第3期18卷 490-508页

作者： Pham van vinh Le Quang Huy Department of Solid Mechanics Le Quy Don Technical University236 Hoang Quoc VietHanoiViet Nam Institute of Techniques for Special Engineering Le Quy Don Technical University236 Hoang Quoc VietHanoiViet Nam

This study focusses on establishing the finite element model based on a new hyperbolic sheareformation theory to investigate the static bending,free vibration,and buckling of the functionally graded sandwich plates with *** novel sandwich plate consists of one homogenous ceramic core and two different functionally graded face sheets which can be widely applied in many fields of engineering and defence *** discrete governing equations of motion are carried out via Hamilton’s principle and finite element *** computation program is coded in MATLAB software and used to study the mechanical behavior of the functionally graded sandwich plate with *** present finite element algorithm can be employed to study the plates with arbitrary shape and boundary *** obtained results are compared with available results in the literature to confirm the reliability of the present ***,a comprehensive investigation of the effects of several parameters on the bending,free vibration,and buckling response of functionally graded sandwich plates is *** numerical results shows that the distribution of porosity plays significant role on the mechanical behavior of the functionally graded sandwich plates。

关键词： Functionally graded sandwich plates Porous plates Hyperbolic shear deformation theory Bending analysis Free vibration analysis Buckling analysis

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Effectiveness of bee venom acupuncture for patients suffering from periarthritis humeroscapularis

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Journal of Traditional Chinese Medicine 2023年第4期43卷 795-800页

作者： Minh Duc Nguyen Thanh van tran Quoc vinh Nguyen Cay Doan Ha Linh Vu Phuong Dang Senior Specialist Clinic National Hospital of AcupunctureHanoi 1000Vietnam Department of Senior Specialist National Hospital of Acupuncture Hanoi 1000Vietnam Department of Senior Specialist Military Institute of Traditional MedicineHanoi 1000Vietnam Department of minimally invasive spine National Hospital of AcupunctureHanoi 1000Vietnam Department of Medicine Dai Nam UniversityHanoi 1000Vietnam

OBJECTIVE:To evaluate the efficacy of bee venom acupuncture in humeroscapularis(PHS)***:One hundred and twenty patients diagnosed with PHS were assigned into four groups:BV1(0.01 mg/kg),BV2(0.005 mg/kg),BV3(0.0025 mg/kg),and control group(vitamin B1 plus novocain 3%injection)with 15 d of *** outcomes of the study including visual analogue scale(VAS)score andβ-endorphin,inflammatory cytokines including interleukin-10(IL-10),IL-1βand tumor necrosis factorα(TNF-α)and shoulder function score were assessed at baseline,after 10 and 15 d of ***:All four groups reported statistically significant improvement in VAS score,motion range,and shoulder function score(P<0.01),only the BV3 group showed significant increase of anti-inflammatory(IL-10)and decrease of pro-inflammatory(IL-1β,TNF-α)cytokines after treatment(P<0.05).The BV3 group presented a significant difference between all outcomes compared to the control and other ***:BV3 groups showed better recovery including reduced pain,improved motor function and normalized inflammatory cytokines than current therapy used in Vietnam and other groups.

关键词： periarthritis humeroscapularis bee venom acupuncture visual analogue scale range of motion articular shoulder function score inflammatory cytokines

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Fabrication and characterization of YVO_4:Eu^(3+) nanomaterials by the microwave technique

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Journal of Rare Earths 2011年第12期29卷 1137-1141页

作者： tran Thu Huong Vu Duc Tu tran Kim Anh Le Thi vinh Le Quoc Minh Institute of Materials Science Vietnamese Academy of Science and Technology University of Engineering and Technology National University Hanoi Departments of Chemistry Hanoi University of Mining and Geology

Fabrication and characterization of YVO4：Eu^3＋ nanophosphors prepared by microwave （MW） irradiation assisted soft template synthesis were reported. The effects of synthesis conditions such as different powers of MW irradiation, pH values and concentration of reac- tion materials on properties of nanophosphor were also investigated to obtain the controllable size, morphology and high luminescence efficiency. Morphology, crystalline structure, and optical properties were characterized by field emission scanning electron microscopy （FE-SEM）, X-ray diffraction （XRD） and fluorescence spectroscopy, respectively. The results showed that YVOa：Eu^3＋ nanophosphors were obtained by using diethyleneglycol （DEG） as soft template, with pH values in the range of 4 to 12, upon microwave irradiation from 300 to 900 W, at temperature of 80 ℃. The high fluorescent YVOa：Eu^3＋ nanocrystals obtained with size from 15 nm down to 8 nm are more effective to develop an ultrahigh sensitive fluorescent label for biomolecule, cell and tissue.

关键词： microwave synthesis method DEG soft template YVO4:Eu^3+ nanophosphor luminescence rare earths

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Fuzzy Feedback Control for Electro-Hydraulic Actuators

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Intelligent Automation & Soft Computing 2023年第5期36卷 2441-2456页

作者： Tan Nguyen van Huy Q.tran vinh Xuan Ha Cheolkeun Ha Phu Huynh Minh School of Engineering-Technology Thu Dau Mot UniversityThu Dau Mot City590000Vietnam Faculty of Engineering-Technology Nguyen Tat Thanh UniversityHo Chi Minh City754000Vietnam Hue Industrial College Hue City530000Vietnam Robotics and Mechatronics Lab University of UlsanUlsan City44610Korea

Electro-hydraulic actuators(EHA)have recently played a signiﬁcant role in modern industrial applications,especially in systems requiring extremely high *** can be explained by EHA’s ability to precisely control the position and force through advanced sensors and innovative control *** of the promising approaches to improve control accuracy for EHA systems is applying classical to modern control algorithms,in which the proportional–inte-gral–derivative(PID)algorithm,fuzzy logic controller,and a hybrid of these methods are popular *** this paper,we developed a novel version of the fuzzy control algorithm and linear feedback control method,namely fuzzy lin-ear feedback control,to improve the control *** achieve the highest performance,weﬁrst designed a mathematical EHA model based on the Matlab/Simulink software packages thanks to the selected parameters,which are similar to a real EHA ***,we respectively applied PID,fuzzy PID(FPID),and fuzzy linear feedback control(FLFC)before comparing them to have a full view of the outstanding advantages of the proposed *** simulation results showed that the proposed FLFC algorithm is approximately 99%and 77%super-ior in performance to the PID and feedback control algorithms,respectively.

关键词： Electro-hydraulic actuator fuzzy PID feedback control

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Vibration characteristics of sandwich plates with an auxetic honeycomb core and laminated three-phase skin layers under blast load

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Defence Technology（防务技术） 2023年第6期24卷 148-163页

作者： Quoc-Hoa Pham van Ke tran Trung Thanh tran Faculty of Engineering and Technology Nguyen Tat Thanh UniversityHo Chi Minh CityViet Nam Faculty of Mechanical Engineering Le Quy Don Technical UniversityHanoiViet Nam

In this article,vibration characteristics of sandwich plates with an auxetic honeycomb core and laminated three-phase skin layers subjected to blast load are ***-order ES-MITC3 element based on higher-order shear deformation theory(HSDT)to achieve the governing *** sandwich plates with the ultra-light feature of the auxetic honeycomb core layer(negative Poisson’s ratio)and reinforced by two laminated three-phase skin *** obtained results in our work are compared with other previously published to confirm accuracy and *** addition,the effects of parameters such as geometrical and material parameters on the vibration characteristics of sandwich plates with an auxetic honeycomb core and laminated three-phase skin layers are fully investigated.

关键词： Laminated three-phase Sandwich plate Auxetic honeycomb ES-MITC3 element High-order shear deformation theory

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Fabrication and properties of high efficiency luminescent nanorods EuPO_4·H_2O by soft template method

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Journal of Rare Earths 2011年第12期29卷 1174-1177页

作者： tran Thu Huong tran Kim Anh Le Thi vinh W.Strek Hoang Thi Khuyen Le Quoc Minh Institute of Materials Science Vietnam Academy of Science and Technology Department of Chemistry Hanoi University of Mining and Geology Institute of Low Temperature and Structure Research University of Engineering and Technology National University Hanoi

Europium orthophosphate monohydrate （EuPO4·H2O） nanorods with typical dimensions of about 10-30 nm in diameter and 300-500 nm in length were prepared by using the soft template method. The effects of using diethylene glycol （DEG） and polyethylene glycol （PEG） polymers as well as the pH values on the size, crystalline structure and morphology of EuPO4·H2O nanorods were investigated. Field emission scanning electron microscopy （FESEM） and X-ray diffraction （XRD） data of the prepared samples were elucidated. The nanorods were highly uniform and their mean length was reduced by using DEG and PEG as soft template agents. For all prepared samples, the rhabdophanetype hexagonal EuPO4·H2O was the dominated phase. The photoluminescence （PL） spectroscopy measurements of EuPO4·H2O nanorods revealed that, under UV excitation, EuPO4·H2O nanorods exhibited strong luminescence with narrow bands corresponding to the intra-4f transitions of ^5D0→^7Fj （j=1, 2, 3, 4） of Eu^3＋ ions. The peaks were found at 594 nm （^5D0→^7F1）, 619 nm （^5D0→^7F2）, 652 nm （^5D0→^7F3）, and 697 nm （^5D0→^7F4）, with the strongest emission at 594 nm.

关键词： soft template method EuPO4·H2O nanorods fluorescence rare earths

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Effectiveness on post-stroke hemiplegia in patients:electroacupuncture plus cycling vs electroacupuncture alone

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Journal of Traditional Chinese Medicine 2023年第2期43卷 352-358页

作者： Minh Duc Nguyen Thanh van tran Quoc vinh Nguyen Ninh Khac Nguyen Son Truong Vu Luu Trong Nguyen Linh Vu Phuong Dang Senior Specialist Clinic National Hospital of AcupunctureHanoi 1000Vietnam Department of Senior Specialist National Hospital of Acupuncture Hanoi 1000Vietnam Department of Senior Specialist Military Institute of Traditional MedicineHanoi 1000Vietnam Department of Training and Science National Hospital of AcupunctureHanoi 1000Vietnam Department of Senior Specialist National Hospital of AcupunctureHanoi 1000Vietnam Department of Rehabilitation 108 Military Central HospitalHanoi 1000Vietnam Department of Medicine Dai Nam UniversityHanoi 1000Vietnam

OBJECTIVE:To evaluate the effectiveness of cycling in combination with electroacupuncture in treatment of poststroke hemiplegia patients at National Hospital of Acupuncture,***:The study was designed as a single-centre,outcome-assessor-blinded parallel randomised controlled trial with 120 post-stroke hemiplegia patients randomly assigned into two groups:electroacupuncture plus cycling(CT group) and electroacupuncture(AT group).Patients were assessed before and after the treatment(using muscle grading,modified Rankin,Barthel,Orgorozo scores and electromyography).Statistical Man–Whitney U test,and Fisher’s exact tests were used to compare between CT and AT ***:The results reported statistically significant improvement in motor function in patients suffering from hemiplegia following ischemic stroke in both CT and AT *** in CT group experienced a greater improvement compared to those in AT group including better muscle contraction(increased frequency and amplitude of electromyography and increased muscle grading scale);increased recovery(Orgogozo scale),increased independency(Barthel scale) and decreased disability(Modified Rankin scale)(P < 0.01).CONCLUSIONS:Combination with cycling training significantly improves the recovery of post-stroke patients treated with electroacupuncture.

关键词： electroacupuncture cycle training post-stroke hemiplegia

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