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Effects of dietary tert-butylhydroquinone on domoic acid metabolism and transcription of detoxification-related liver genes in red sea bream Pagrus major

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Chinese Science Bulletin 2013年第16期58卷 1906-1911页

作者： HE Shan LIANG XuFang SHEN Dan ZHANG WenBing mai KangSen Key Laboratory of Freshwater Animal Breeding of Ministry of Agriculture College of Fisheries Huazhong Agricultural University Key Laboratory of Mariculture of Ministry of Education Ocean University of China

Domoic acid (DA) is a neuroexcitatory amino acid that is produced by Pseudo-nitzschia during harmful algal blooms (HAB). Accumulation of DA can be transferred through food chain and cause neuronal damage in marine animal and in human. Like other algal toxins, DA was suggested to increase the oxidative stress and increase the detoxification-related gene expression in fish. The widely used food antioxidant, tert-butylhydroquinone (tBHQ), was known to induce a wide range of antioxidative potentials such as elevation of the glutathione levels and glutathione S-transferases (GSTs), via the activation of antioxidant response elements (AREs). In this study, the influences of dietary tBHQ on domoic acid (DA) metabolism and detoxification-related gene transcription were investigated both in vivo and in vitro. Oral administration of tBHQ resulted in significant decreases of DA accumulation of liver tissues in which red sea bream were fed with a single dose of 10 mg DA and 100 mg tBHQ per kg body weight per fish. Real-time PCR further revealed that the mRNA levels of AHR/ARNT/CYP1A1/GSTA1/GSTR were up-regulated in the above liver tissues at 72 h post tBHQ treatment. In consistence, tBHQ exposure also resulted in increased mRNA transcription of GSTA1, GSTA2 and GSTR in cultured red sea bream hepatocytes. Collectively, our findings in this research suggested that the dietary intake of tBHQ accelerated DA metabolism in fish, through mechanisms involving altered transcription of detoxification- related liver genes.

关键词： mRNA转录相关基因软骨藻酸特丁基对苯二酚酸代谢真鲷解毒肝脏

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Approaching high oxygen evolution reaction performance by synergetic dual-ion leaching

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Nano Research 2024年第9期17卷 7975-7983页

作者： Hancheng Ma Yao Ding Jianqi Li Wei Peng Liqiang mai School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China

Self-reconstruction of catalysts during oxygen evolution reaction(OER)is crucial for the development of energy conversion ***,the relationship between the specific atomic structure of pre-catalysts and their electrocatalytic behavior after reconstruction via dual-ion leaching has not been extensively *** this work,we design a highly effective non-noble metal OER catalyst with heterointerface through continuous self-reconstruction of Co_(2)(OH)_(3)Cl@NiMoO_(4)as pre-catalyst by a straightforward dual-ion(***_(4)^(2-)and Cl^(-))***-situ Raman and in-situ Fourier transform infrared(FT-IR)spectroscopy have precisely identified the progressive phase transformation of the pre-catalyst during self-reconstruction,which results in a stable heterojunction of CoOOH and NiOOH(CoOOH@NiOOH).Further calculations based on density functional theory(DFT)of CoOOH@NiOOH evident that more electrons will be aggregated in the Fermi level of ***,Gibbs free energy(ΔG)for different OER steps of CoOOH@NiOOH exhibit lower energy costs of all intermediates,implying the well catalytic ***,the catalyst derived from dual-ion leaching displays outstanding OER performance,characterized by an overpotential of 275 mV at a current density of 10 mA·cm^(-2)and exceptional stability over 12 h *** work successfully paves a way of finding high-performance OER catalysts based on non-noble metal through dual-ion leaching during self-reconstruction.

关键词： dual-ion leaching oxygen evolution reaction chemical reconstruction NiMoO_(4) Co_(2)(OH)_(3)Cl

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Accelerometer error estimation and compensation for three-axis gyro-stabilized camera mount based on proportional multiple-integral observer

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Science China(Technological Sciences) 2014年第12期57卷 2387-2395页

作者： LI Shu Sheng ZHONG mai Ying ZHAO Yan School of Instrument Science & Opto-engineering Beihang University

This paper deals with the problem of accelerometer error estimation and compensation for a three-axis gyro-stabilized camera mount. In a dynamic environment, the aircraft motion acceleration affects the accelerome ：er output and causes a degradation of attitude steady accuracy. In order to improve control accuracy, this paper proposes a proportional multiple-integral observer- based control strategy to estimate and compensate the accelerometer error. The basic idea of this paper is to approximate the error property by using a q-order polynomial function and extend the error and its derivatives as augmented states. Then a proportional multiple-integral observer is developed to estimate the error, with which the relationship between the error and the imbalance torque is formulated. The estimated value is compared to an angle threshold, the result of which is used to compen- sate the accelerometer output. Through static and vehicle-mounted experiments, it is demonstrated that compared with the tra- ditional method, the proposed method can improve the attitude steady accuracy effectively.

关键词： three-axis gyro-stabilized camera mount accelerometer error estimation and compensation proportional multiple-integralobserver imbalance torque

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Chloride ion battery:A new emerged electrochemical system for next-generation energy storage

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Journal of Energy Chemistry 2024年第1期88卷 154-168,I0004页

作者： Shulin Chen Lu Wu Yu Liu Peng Zhou Qinyou An Liqiang mai State Key Laboratory of Advanced Technology for Materials Synthesis and Processing School of Materials Science and EngineeringWuhan University of TechnologyWuhan 430070HubeiChina State Key Laboratory of Refractories and Metallurgy Institute of Advanced Materials and NanotechnologyWuhan University of Science and TechnologyWuhan 430081HubeiChina

In the scope of developing new electrochemical concepts to build batteries with high energy density,chloride ion batteries(CIBs)have emerged as a candidate for the next generation of novel electrochemical energy storage technologies,which show the potential in matching or even surpassing the current lithium metal batteries in terms of energy density,dendrite-free safety,and elimination of the dependence on the strained lithium and cobalt ***,the development of CIBs is still at the initial stage with unsatisfactory performance and several challenges have hindered them from reaching *** this review,we examine the current advances of CIBs by considering the electrode material design to the electrolyte,thus outlining the new opportunities of aqueous CIBs especially combined with desalination,chloride redox battery,*** respect to the developing road of lithium ion and fluoride ion batteries,the possibility of using solid-state chloride ion conductors to replace liquid electrolytes is tentatively *** beyond,perspectives and clear suggestions are concluded by highlighting the major obstacles and by prescribing specific research topics to inspire more efforts for CIBs in large-scale energy storage applications.

关键词： Chloride ion battery Anion shuttling Conversion reaction Chloride redox

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Diagnosis,treatment protocols,and outcomes of liver transplant recipients infected with COVID-19

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World Journal of Clinical Cases 2023年第10期11卷 2140-2159页

作者： mai Hashem Mohamed El-Kassas Tropical Medicine and Gastroenterology Assiut University HospitalAssiut 71515Egypt Department of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt

Several cases of fatal pneumonia during November 2019 were linked initially to severe acute respiratory syndrome coronavirus 2,which the World Health Organization later designated as coronavirus disease 2019(COVID-19).The World Health Organization declared COVID-19 as a pandemic on March 11,*** the general population,COVID-19 severity can range from asymptomatic/mild symptoms to seriously *** mortality rate could be as high as 49%.The Centers for Disease Control and Prevention have acknowledged that people with specific underlying medical conditions,among those who need immunosuppression after solid organ transplantation(SOT),are at an increased risk of developing severe illness from *** transplantation is the second most prevalent SOT *** to their immunosuppressed state,liver transplant(LT)recipients are more susceptible to serious ***,comorbidities and prolonged immunosuppression among SOT recipients enhance the likelihood of severe *** is crucial to comprehend the clinical picture,immunosuppressive management,prognosis,and prophylaxis of COVID-19 infection because it may pose a danger to transplant *** review described the clinical and laboratory findings of COVID-19 in LT recipients and the risk factors for severe disease in this population *** the following sections,we discussed current COVID-19 therapy choices,reviewed standard practice in modifying immunosuppressant regimens,and outlined the safety and efficacy of currently licensed drugs for inpatient and outpatient ***,we explored the clinical outcomes of COVID-19 in LT recipients and mentioned the efficacy and safety of vaccination use.

关键词： COVID-19 Liver transplantation Recipient Protocols Outcomes

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The leaching of additive-derived flame retardants(FRs) from plastics in avian digestive fluids:The significant risk of highly lipophilic FRs

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Journal of Environmental Sciences 2019年第11期31卷 200-207页

作者： Huiying Guo Xiaobo Zheng Shuling Ru Xiaojun Luo Bixian mai State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Protection and Resources Utilization Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China College of Resources and Environment South China Agricultural University Guangzhou 510642 China University of the Chinese Academy of Sciences Beijing 100049 China

The exposure to plastic debris and associated pollutants for wildlife is of urgent concern,but little attention has been paid on the transfer of plastic additives from plastic debris to *** the present study,the leaching of incorporated flame retardants (FRs),including polybrominated diphenyl ethers (PBDEs),alternative brominated FRs (AFRs),and phosphate flame retardants (PFRs),from different sizes of recycled acrylonitrile-butadiene-styrene (ABS) polymer were investigated in avian digestive *** impact of co-ingested sediment on the leaching of additive-derived FRs in digestive fluids was also *** the recycled ABS,BDE 209 (715 μg/g) and 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE,1766 μg/g) had the highest concentrations among all target *** leaching proportions of FRs were higher in finer sizes of *** leaching proportions of FRs from recycled ABS increased with elevated logKow of *** the tests with coexisted ABS and sediment,hexato deca-BDEs,BTBPE,and decabromodiphenyl ethane (DBDPE) migrated from ABS to sediment,which resulted in the less bioaccessible fractions of these FRs in gut *** lipophilic chemicals tended to be adsorbed by sediment from *** results suggest the migration of additive-derived FRs from plastics to other indigestible materials in digestive *** findings in this study provide insights into the transfer of additive-derived FRs from plastics to birds,and indicate the significant contribution of FR-incorporated plastics to bioaccumulation of highly lipophilic FRs.

关键词： Recycled plastics Digestive fluids Flame retardants Leaching

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MICROCALORIMETRIC STUDIES OF SURFACE ACID/BASE PROPERTIES OF REDUCED IRON／MAGNESIUM CATALYSTS

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Chinese Journal of Catalysis 1996年第4期17卷 8-9页

作者：Ｔｕ　ＭａｉＳｈｅｎ　ＪｉａｎｙｉＣｈｅｎ　ＹｉＤｅｐａｒｔｍｅｎｔ　ｏｆ　ＣｈｅｍｉｓｔｒｙＮａｎｊｉｎｇ　Ｕｎｉｖｅｒｓｉｔｙ

ＭＩＣＲＯＣＡＬＯＲＩＭＥＴＲＩＣＳＴＵＤＩＥＳＯＦＳＵＲＦＡＣＥＡＣＩＤ／ＢＡＳＥＰＲＯＰＥＲＴＩＥＳＯＦＲＥＤＵＣＥＤＩＲＯＮ／ＭＡＧＮＥＳＩＵＭＣＡＴＡＬＹＳＴＳ＊ＴｕＭａｉ，ＳｈｅｎＪｉａｎｙｉ＊＊，Ｃｈｅｎ... 详细信息

ＭＩＣＲＯＣＡＬＯＲＩＭＥＴＲＩＣＳＴＵＤＩＥＳＯＦＳＵＲＦＡＣＥＡＣＩＤ／ＢＡＳＥＰＲＯＰＥＲＴＩＥＳＯＦＲＥＤＵＣＥＤＩＲＯＮ／ＭＡＧＮＥＳＩＵＭＣＡＴＡＬＹＳＴＳ＊ＴｕＭａｉ，ＳｈｅｎＪｉａｎｙｉ＊＊，ＣｈｅｎＹｉ（ＤｅｐａｒｔｍｅｎｔｏｆＣｈ...

关键词： SURFACE ACID

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A new insight into rapid oxidation of alloy 925 contaminated by oxide powder

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Rare Metals 2021年第7期40卷 1872-1880页

作者： He Jiang Jian-Xin Dong mai-Cang Zhang Jiang-Yang Li Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China

Rapid oxidation takes place both in the laboratory and in industrial conditions when alloy 925 is contaminated by oxide powder,and the oxidation rate is much higher than ***,the rapid oxidation behavior and mechanism of alloy 925 were investigated by a series of comparison tests at 1160℃.It is found that the oxide powder produced during the oxidation process is mainly composed of NiCr_(2)O_(4)spinel,accompanied by NiO and NiMoO_(4).The oxide powder plays a triggering role in the rapid oxidation of alloy 925,as NiO has a strong affinity with O.A composition adjustment experiment of alloy 925 shows that rapid oxidation is the synergetic effect of Mo and Cu in the *** and Cu easily combine to form low melting point *** formation and volatilization of MoO_(3)oxide can destroy the completeness of the protective oxide *** MoO_(3)flux can dissolve protective Cr_(2)O_(3)and prevent the repair of the oxide layer and also promote the formation of nonprotective and easy-spall NiCr_(2)O_(4)*** synergetic effect of Cu and Mo in accelerating oxidation should be considered in any nickel-based alloy with a high content of Cu and Mo.

关键词： Rapid oxidation Synergetic effect Nickelbased superalloy

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Comparative Study on the Leaching Dynamic Properties of Five Kinds of Microparticulate forms of Vitamin B_1

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High Technology Letters 2001年第2期7卷 1-5页

作者：吴格天 mai Kangsen Zhu Wei Aquaculture Research Laboratory College of Fisheries Ocean University of Qingdao

With an aim to reduce leaching of water soluble vitamins, the leaching properties of five kinds of microparticulate forms of vitamin B 1 are investigated by means of dynamic system. These microparticles include: alginate and alginate CMC microcapsules prepared by emulsion coacervation process (ECP), alginate and gelatin microcapsules prepared by spray drying process (SDP), and alginate microbound. The results show these five microparticulate forms of VB 1 can reduce leaching significantly compared to crystalline form VB 1, and the leaching rates at different intervals, diameters and encapsulation efficiencies ( EE ) are significantly different among all kinds of microparticles (ANOVA, P <0.05). The leaching properties of the five microparticles are in accord with Higuchi equation. Based on the regression equation, the half loss time ( T 50 ) is *** conclusion, the alginate CMC microencapsule is a potential tool to reduce leaching of water soluble vitamins.

关键词： Leaching Microencapsulation Microbound Vitamin B 1

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Conformation of an Amphiphilic Comb-like Copolymer in a Selective Solvent

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Chinese Journal of Polymer Science 2023年第9期41卷 1386-1391,I0006页

作者： Peng Hao Xing-Hong mai Qiao-Yue Chen Ming-Ming Ding Xinjiang Laboratory of Phase Transitions and Microstructures in Condensed Matter Physics College of Physical Science and TechnologyYili Normal UniversityYining835000China School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou510006China

We study the conformation of an amphiphilic comb-like copolymer in a selective solvent by using Brownian dynamics *** results demonstrate that,there is an optimal total degree of polymerization to form spherical *** when the total degree of polymerization is less than the optimal total degree of polymerization,a unimolecular spherical micelle can be formed,otherwise,the spherical micelle will be transformed into a cylindrical *** the total degree of polymerization is less than the optimal total degree of polymerization,the radius of gyration and the stretching factor meet an exponential relationship,where the power exponent decreases with the increase of the length of hydrophilic side *** fundamental principles uncovered here afford insights for the optimization of molecular design of amphiphilic comb-like copolymers in various applications.

关键词： Comb-like copolymer Conformation Selective solvent Brownian dynamics

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