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Woody plant taxonomic,functional,and phylogenetic diversity decrease along elevational gradients in Andean tropical montane forests:Environmental filtering and arrival of temperate taxa

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Plant Diversity 2024年第4期46卷 491-501页

作者： Guillermo Bañares-de-Dios Manuel J.Macía Gabriel Arellano Íñigo Granzow-de la Cerda Julia Vega-álvarez Itziar Arnelas Carlos I.Espinosa Norma Salinas Luis Cayuela departamento de Biología y Geología Física y Química InorgánicaUniversidad Rey Juan CarlosCalle Tulipán s/nMóstolesMadridES-28933Spain departamento de Biología Área de BotánicaUniversidad Autónoma de MadridCalle Darwin 2MadridES-28049Spain Centro de Investigación en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autónoma de MadridCalle Darwin 2MadridES-28049Spain Ecology and Evolutionary Biology University of MichiganAnn ArborMI 48109USA Oikobit LLC ***AlbuquerqueNM87120USA Real Jardín Botánico–CSIC Plaza Murillo 2MadridES-28014Spain departamento de Biología Animal EcologíaParasitologíaEdafología y Química AgrícolaUniversidad de SalamancaCalle Donantes de Sangre s/nSalamancaES-37007Spain departamento de Biodiversidad Ecología y EvoluciónUniversidad Complutense de MadridCalle JoséAntonio Nováis 12Ciudad UniversitariaES-28040Spain departamento de Ciencias Biológicas y Agropecuarias Universidad Técnica Particular de LojaA.P.11-01-608 LojaEcuador Sección Química Pontificia Universidad Católica del PerúA.P.Lima 32LimaPeru ECI School of Geography and EnvironmentUniversity of OxfordOX13QYOxfordshireUnited Kingdom Instituto de Investigación en Cambio Global(IICG-URJC) Universidad Rey Juan CarlosCalle Tulipán s/nMóstolesMadridES-28933Spain

Mountains are paramount for exploring biodiversity patterns due to the mosaic of topographies and climates encompassed over short *** research has traditionally focused on taxonomic diversity when investigating changes along elevational gradients,but other facets should be *** first time,we simultaneously assessed elevational trends in taxonomic,functional,and phylogenetic diversity of woody plants in Andean tropical montane forests and explored their underlying ecological and evolutionary *** investigation covered four transects(traversing ca.2200 m a.s.l.) encompassing 114 plots of 0.1 ha across a broad latitudinal range(ca.10°).Using Hill numbers to quantify abundance-based diversity among 37,869 individuals we observed a consistent decrease in taxonomic,functional,and phylogenetic diversity as elevation increased,although the decrease was less pronounced for higher Hill *** exception was a slight increase in phylogenetic diversity when dominant species were *** decrease in taxonomic and functional diversity might be attributed to an environmental filtering process towards highlands,where the increasingly harsher conditions exclude species and functional ***,the differences in steepness decrease between Hill orders suggest that rare species disproportionately contribute to functional *** phylogenetic diversity the shifting elevational trend between Hill orders indicates a greater than previously considered influence in central Andean highlands of tropical lowlands originated species with strong niche conservatism relative to distantly related temperate *** could be explained by a decreasing presence and abundance of temperate,extratropical taxa towards the central Andes relative to northern or southern Andes,where they are more prevalent.

关键词： Altitudinal gradients Andes Environmentalﬁltering Out of the Tropical Lowlands Functional rarity Tropical Niche Conservatism

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From Helicobacter pylori infection to gastric cancer:Current evidence on the immune response

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World Journal of Clinical Oncology 2022年第3期13卷 186-199页

作者： vinícius lima de Souza Gonçalves Maria Luísa Cordeiro Santos Marcel Silva Luz Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Cláudio lima Souza Márcio Vasconcelos Oliveira Fabrício Freire de Melo Universidade Estadual do Sudoeste da Bahia Campus Vitória da ConquistaVitória da Conquista 45083-900BahiaBrazil Universidade Federal da Bahia Instituto Multidisciplinar em SaúdeVitória da Conquista 45029-094BahiaBrazil

Gastric cancer(GC)is the result of a multifactorial process whose main components are infection by Helicobacter pylori(***),bacterial virulence factors,host immune response and environmental *** development of the neoplastic microenvironment also depends on genetic and epigenetic changes in oncogenes and tumor suppressor genes,which results in deregulation of cell signaling pathways and apoptosis *** review summarizes the main aspects of the pathogenesis of GC and the immune response involved in chronic inflammation generated by ***.

关键词： Gastric cancer Helicobacter pylori Chronic inflammation Host immune response

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Syndemic aspects between COVID-19 pandemic and social inequalities

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World Journal of Methodology 2022年第5期12卷 350-364页

作者： Jonathan Santos Apolonio Ronaldo Teixeira da Silva Júnior Beatriz Rocha Cuzzuol Glauber Rocha lima Araújo Hanna Santos Marques Isadora de Souza Barcelos Luana Kauany de SáSantos Luciano Hasimoto Malheiro vinícius lima de Souza Gonçalves Fabrício Freire de Melo Universidade Federal da Bahia Instituto Multidisciplinar em SaúdeVitória da Conquista 45029-094BahiaBrazil Universidade Estadual do Sudoeste da Bahia Campus Vitória da ConquistaVitória da Conquista 45083-900BahiaBrazil

Although the coronavirus disease 2019(COVID-19)pandemic has reached all over the world population,it has demonstrated a heterogeneous impact on different *** most vulnerable communities which coexist daily with the social inequalities like low access to hygiene and personal protection products,crowded residences,and higher levels of chronic diseases have a higher risk of contact and the spread of infection,beyond unfavorable clinical *** elevation of the risk of infection exposure can be related to gender due to the presence of a larger contingent of women in essential services,as well as frontline and cleaning professionals who regardless of gender have the greatest exposure to the *** exposures can contribute to the development of fear of contaminating themselves or their family members associated also with the work stress,both of which are related to the emergence of mental disturbances in these ***,conditions of unsanitary living and low socioeconomic status,populations at war,pre-existing social barriers,and ethnicity have contributed to more impact of the pandemic both in the exposure to the virus and access to health services,COVID-19 management,and management of other *** the same time,factors such as the closing of non-essential services,the loss of jobs,and the increase in household spending aggravated the social vulnerabilities and impacted the family ***,the COVID-19 pandemic contributed still more to the impact on women's health since it propitiated a favorable environment for increasing domestic violence rates,through the segregation of women from social life,and increasing the time of the victims with their aggressors.

关键词： COVID-19 Minority groups Pandemic Social inequalities Socioeconomic factors

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Free Cyclic Actions on Surfaces and the Borsuk-Ulam Theorem

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Acta Mathematica Sinica,English Series 2022年第10期38卷 1803-1822页

作者： Daciberg lima GONCalves John GUASCHI vinicius Casteluber LAASS departamento de Matematica IMEUniversidade de Sao PauloRua do Matao 1010 CEP:05508-090Sao Paulo-SPBrazil Normandie Univ. UNICAENCNRSLMNO14000 CaenFrance Universidade Federal da Bahia IMEDepartamento de MatematicaAv.Milton SantosS/N Ondina CEP:40170-110Salvador-BABrazil

Let M and N be topological spaces,let G be a group,and letτ:G×M→M be a proper free action of *** this paper,we define a Borsuk-Ulam-type property for homotopy classes of maps from M to N with respect to the pair(G,τ)that generalises the classical antipodal Borsuk-Ulam theorem of maps from the n-sphere S^(n) to R^(n).In the cases where M is a finite pathwise-connected CWcomplex,G is a finite,non-trivial Abelian group,τis a proper free cellular action,and N is either R^(2) or a compact surface without boundary different from S^(2) and RP^(2),we give an algebraic criterion involving braid groups to decide whether a free homotopy class β∈[M,N]has the Borsuk-Ulam *** an application of this criterion,we consider the case where M is a compact surface without boundary equipped with a free actionτof the finite cyclic group *** terms of the orient ability of the orbit space Mof M by the actionτ,the value of n modulo 4 and a certain algebraic condition involving the first homology group of M,we are able to determine if the single homotopy class of maps from M to R^(2) possesses the Borsuk-Ulam property with respect to(Z_(n),τ).Finally,we give some examples of surfaces on which the symmetric group acts,and for these cases,we obtain some partial results regarding the Borsuk-Ulam property for maps whose target is R^(2).

关键词： Borsuk-Ulam theorem cyclic groups braid groups surfaces

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Impacts of COVID-19 on children and adolescents:A systematic review analyzing its psychiatric effects

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World Journal of Psychiatry 2022年第11期12卷 1313-1322页

作者： Italo Wanderson de Moura Gabriel Danielly Gonçalves Sombra lima Jeully Pereira Pires Nélio Barreto Vieira Aloisio Antonio Gomes de Matos Brasil Yara Talita Gomes Pereira Erika Galvao de Oliveira HildsonLeandro de Menezes Nadia Nara Rolim lima Alberto Olavo Advíncula Reis Ruan Neto Pereira alves Uanderson Pereira da Silva Jucier Gonçalves Junior Modesto Leite Rolim-Neto School of Medicine Faculty of Medicine of Juazeiro do Norte-FMJ/IDOMEDJuazeiro do Norte 63040-360CearaBrazil School of Medicine Federal University of CaririBarbalha 63048-080CearaBrazil Mais Médicos Program Federal Government of Brazil-Ministry of HealthIguatu 63048-080CearaBrazil Julio alves de Lira Hospital and Maternity Hospital HALHMBelo Jardim 55157-290PernambucoBrazil Nursing department Doctor Leão Sampaio University Center-UNILEAOJuazeiro do Norte 63.041-140CearaBrazil Julio alves de Lira Hospital and Maternity Hospital JALHMBelo Jardim 55157-290PernambucoBrazil Graduate Program(Post-Doctoral)in Neuro-Psychiatry UFPERecife 50670-901PernambucoBrazil Postgraduate Program(Master’s and Doctorate)in Public Health University of São Paulo-USPSão Paulo 01246-904São PauloBrazil School of Education USPSão Paulo 05508-040São PauloBrazil Internal Medicine-Division of Rheumathology at Hospital das Clínicas São Paulo UniversitySão Paulo 01246-903São PauloBrazil

OBJECTIVE To summarize the most relevant data from a systematic review on the impact of COVID-19 on children and adolescents,particularly analyzing its psychiatric *** This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA)guidelines and included experimental studies(randomized-individually or pooled-and non-randomized controlled trials),observational studies with a group for internal comparison(cohort studies-prospective and retrospective-and case-control)and qualitative studies in the period from 2021 to *** The search identified 325 articles;we removed 125 *** selected 200 manuscripts,chosen by title and selected *** excluded 50 records after screening titles and abstracts,as they did not meet the inclusion *** retrieved 150 records selected for a full *** excluded 90 text articles and we selected 25 records for the(n)***:Due to the short period of data collection,from 2021 to 2022,there is a possibility of lack of relevant studies related to the mental health care of children and *** addition,there is the possibility of publication bias,such as only significant findings being *** The impact of COVID-19 on the mental health of children and adolescents is of great concern to child and youth *** such as fear,anxiety,panic,depression,sleep and appetite disorders,as well as impairment in social interactions caused by psychic stress,are punctual markers of pain and psychic suffering,which have increasing impacts on the mental health panorama of children and adolescents globally,particularly in vulnerable and socially at-risk populations.

关键词： Child psychiatry Adolescent psychiatry Mental health COVID-19 Kids Teens

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Effects of nutrients on immunomodulation in patients with severe COVID-19:Current knowledge

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World Journal of Critical Care Medicine 2022年第4期11卷 201-218页

作者： Bruna Teixeira da Costa Glauber Rocha lima Araújo Ronaldo Teixeira da Silva Júnior Luana Kauany de SáSantos vinícius lima de Souza Gonçalves Daniel Bastos alves lima Beatriz Rocha Cuzzuol Jonathan Santos Apolonio Lorena Sousa de Carvalho Hanna Santos Marques Camilo Santana Silva Isadora de Souza Barcelos Márcio Vasconcelos Oliveira Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900BahiaBrazil

Recent research has demonstrated that critically ill patients with coronavirus disease 2019(COVID-19)show significant immune system *** to that,some nutrients that influence immunomodulation have been suggested as a form of treatment against the *** review collected the information on the impact of vitamins on the prognosis of COVID-19,with the intention of facilitating treatment and prevention of the disease risk status in *** collected information was obtained using the PubMed electronic database by searching for articles that relate COVID-19 and the mechanisms/effects of the nutrients:Proteins,glucose,lipids,vitamin B12,vitamin D,calcium,iron,copper,zinc,and magnesium,including prospective,retrospective,and support *** findings reveal an optimal response related mainly to omega-3,eicosapentaenoic acid,docosahexaenoic acid,calcium,and iron that might represent benefits in the treatment of critically ill ***,nutrient supplementation should be done with caution due to the limited availability of randomized controlled studies.

关键词： COVID-19 Immunomodulation Patient care Vitamins Nutrients Micronutrients

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Treatment of patients with multiple brain metastases by isolated radiosurgery:Toxicity and survival

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World Journal of Clinical Oncology 2023年第10期14卷 400-408页

作者： Andrévinícius de Camargo Marcos Duarte de Mattos Murilo Kenji Kawasaki Danilo Nascimento Salviano Gomes Allisson Bruno Barcelos Borges vinicius de lima Vazquez Raphael L C Araujo department of Radiotherapy Barretos Cancer HospitalSão PauloBarretos 14784-400Brazil department of Radiation Therapy Hospital DF Star Rede D´OrBrasília 70390-140Brazil department of Surgery Barretos Cancer HospitalSão PauloBarretos 14784-400Brazil department of Surgery Universidade Federal de São PauloSão Paulo 04024-002Brazil IEP Barretos Cancer HospitalSão PauloBarretos 14784-400Brazil

BACKGROUND Radiosurgery for multiple brain metastases has been more reported recently without using whole-brain ***,the sparsity of the data still claims more information about toxicity and survival and their association with both dosimetric and geometric aspects of this *** To assess the toxicity and survival outcome of radiosurgery in patients with multiple(four or more lesions)brain *** In a single institution,data were collected retrospectively from patients who underwent radiosurgery to treat brain metastases from diverse primary *** with 4-21 brain metastases were treated with a single fraction with a dose of 18 Gy or 20 *** clinical variables collected were relevant to toxicity,survival,treatment response,planning,and dosimetric *** Spearman’s rank correlation coefficients,Mann-Whitney test,Kruskal-Wallis test,and Log-RESULTS From August 2017 to February 2020,55 patients were *** was the most common complaint(38.2%).The median overall survival(OS)for patients with karnofsky performance status(KPS)>70 was 8.9 mo,and this was 3.6 mo for those with KPS≤70(P=0.047).Patients with treated lesions had a median progression-free survival of 7.6 *** were no differences in OS(19.7 vs 9.5 mo)or progression-free survival(10.6 vs 6.3 mo)based on prior *** was no correlation found between reported toxicities and planning,dosimetric,and geometric variables,implying that no additional significant toxicity risks appear to be added to the treatment of multiple(four or more)*** No associations were found between the evaluated toxicities and the planning dosimetric parameters,and no differences in survival rates were detected based on previous treatment status.

关键词： Radiosurgery Brain metastases Radiotherapy Survival Toxicity Cancer

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A comprehensive review of genetic causes of obesity

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World Journal of Pediatrics 2024年第1期20卷 26-39页

作者： Marcio Jose Concepcion-Zavaleta Juan Eduardo Quiroz-Aldave Maria del Carmen Durand-Vasquez Elman Rolando Gamarra-Osorio Juan del Carmen Valencia de la Cruz Claudia Mercedes Barrueto-Callirgos Susan Luciana Puelles-Leon Elena de Jesus Alvarado-Leon Frans Leiva-Cabrera Francisca Elena Zavaleta-Gutierrez Luis Alberto Concepcion-Urteaga Jose Paz-Ibarra Universidad Cientifica del Sur Bolivar 2150 AvenuePueblo Libre15084LimaPeru Division of Medicine Hospital de Apoyo ChepénChepenPeru Division of Family Medicine Hospital de Apoyo ChepénChepenPeru Division of Endocrinology Hospital Victor Lazarte EchegarayTrujilloPeru Division of Pediatrics Hospital de Apoyo ChepenChepenPeru Division of Internal Medicine Hospital de Apoyo ChepenChepenPeru Division of Genetics Universidad Nacional de TrujilloTrujilloPeru Division of Neonatology Hospital Belen de TrujilloTrujilloPeru Division of Internal Medicine Universidad Nacional de TrujilloTrujilloPeru department of Medicine School of MedicineUniversidad Nacional Mayor de San MarcosLimaPeru

Background Obesity is a multifactorial chronic disease with a high,increasing worldwide *** causes account for 7%of the cases in children with extreme *** sources This narrative review was conducted by searching for papers published in the PubMed/MEDLINE,Embase and SciELO databases and included 161 *** search used the following search terms:"obesity","obesity and genetics","leptin","Prader-Willi syndrome",and"melanocortins".The types of studies included were systematic reviews,clinical trials,prospective cohort studies,cross-sectional and prospective studies,narrative reviews,and case *** The leptin-melanocortin pathway is primarily responsible for the regulation of appetite and body ***,several important aspects of the pathophysiology of obesity remain *** causes of obesity can be grouped into syndromic,monogenic,and polygenic causes and should be assessed in children with extreme obesity before the age of 5 years,hyperphagia,or a family history of extreme obesity.A microarray study,an analysis of the melanocortin type 4 receptor gene mutations and leptin levels should be performed for this *** are three therapeutic levels:lifestyle modifications,pharmacological treatment,and bariatric *** Genetic study technologies are in constant development;however,we are still far from having a personalized approach to genetic causes of obesity.A significant proportion of the affected individuals are associated with genetic causes;however,there are still barriers to its approach,as it continues to be underdiagnosed.

关键词： Leptin Melanocortin Obesity Prader-Willi syndrome Precision medicine

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Antioxidant,hypolipidemic and hypoglycemic effect of red wine in wistar rats fed with obesogenic diet

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Food Bioscience 2022年第3期47卷 756-764页

作者： Cornélio Mucaca José Henrique Tavares Filho Luciana lima Arruda André Martins Galvão Maria Bernadete de Sousa Maia Eryka Maria dos Santos alves Eryvelton de Souza Franco Elizabeth do Nascimento department of Nutrition Center of Health SciencesFederal University of Pernambuco (UFPE)Cidade Universitaria50670-901RecifePEBrazil Rural Technology department Federal Rural University of Pernambuco (UFRPE)AD.Manoel de Medeiros Ave.s/nDois Irmãos52171-900RecifePEBrazil department of Physiology and Pharmacology Center of Biological SciencesFederal University of Pernambuco (UFPE)Cidade Universitaria50670-901RecifePEBrazil

The health benefits resulting from the usual ingestion of red wines have been studied in humans and ***,the evaluation of benefits in antioxidant,hypoglycemic and hypolipemic activity concomitant with the use of an obesogenic diet in adult Wistar rats has been little *** present study investigated the use of red wine derived from Northeast Brazil in adult rats fed with an obesogenic diet on antioxidant activity,glucose tolerance,adipose,glycemic and lipemic *** 45-day old male Wistar rats formed two groups:standard diet and westernized *** changes in body mass and glycemic levels,the animals were subdivided into six subgroups (n = 10 per group) and received water,red wine or hydroalcoholic solution by *** data reveal that the moderate and chronic use of red wine improves the glycemic,lipid and oxidative stress profile,being favorable in preventing the risk of cardiovascular diseases in rats fed with an obesogenic diet.

关键词： Dyslipidemia Obesity Rats Westernized diet Red wine

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Epidemiology and Clinical Features of Mycobacterium avium Complex Pulmonary Disease in a Brazilian Amazon Cohort

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Advances in Microbiology 2024年第6期14卷 287-302页

作者： Jose Tadeu Colares Monteiro Adriana Rodrigues Barretto Ruan Seguin Azevedo Quaresma Bianca Miranda Gouveia Ismari Perini Furlaneto Victória Menezes da Costa Yan Corrêa Rodrigues Layana Rufino Ribeiro Ricardo J. de Paula Souza e Guimarães Alex Brito Souza Ana Roberta Fusco da Costa Karla Valéria Batista lima Joao de Barros Barreto University Hospital Federal University of Par Belm Brazil Center for Biological and Health Sciences Ph.D. Program in Parasitic Biology in the Amazon Region (PPGBPA) State University of Par (UEPA) Belm Brazil department of Medicine Centro Universitrio do Par CESUPA Belm Brazil Bacteriology and Mycology Section Evandro Chagas Institute (SABMI/IEC) Ministry of Health Ananindeua Brazil Geoprocessing Laboratory Evandro Chagas Institute/SVSA/MS Ananineua Brazil

The incidence of Mycobacterium avium complex pulmonary disease (MACPD) has been globally increasing. The present study aims to provide a comprehensive analysis of clinical characteristics and treatment response among patients in the Amazon region of Brazil and conduct a retrospective cohort study at a prominent referral hospital in the State of Par, Brazil, from 2012 to 2020. The M. avium group represented 58.9% of cases, followed by M. intracellulare (35.7%), M. colombiense (3.6%), and M. chimaera (1.8%). The majority of patients (73.2%) were female and with an average age of 63 years. Primary clinical manifestations included persistent cough and sputum production. The Charlson comorbidity index (CCI) averaged 2.47, with 36.3% of patients having a CCI score equal to higher than 3. Notably, over 70% of patients had received treatment for pulmonary tuberculosis before initiating treatment for MAC infection. The fibrocavitary radiologic form was the most prevalent (55.4%), frequently exhibiting a bilateral distribution (53.6%). Antimicrobial susceptibility revealed a significant prevalence of MAC resistance to drugs in the therapeutic regimen. despite this, most of the patients experienced clinical improvement (50%). In conclusion, this study highlights a higher prevalence of MAC infections among middle-aged women, with a history of pulmonary tuberculosis treatment and presenting the fibrocavitary radiological form was predominant.

关键词： MACDP Nontuberculous Mycobacteria Mycobacterium avium Lung Disease

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