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Zingiber officinale extends Drosophila melanogaster life span in xenobiotic-induced oxidative stress conditions

Frontiers in Biology 2018年第2期13卷 130-136页

作者： Volodymyr Padalko viktoriya.dzyuba.olena.kozlova.ha.na.sheremet olena Protsenko School of Medicine V.N. Karazin Kharkiv National University 4 Svobody Sq. Kharkiv 61022 Ukraine Department of Membrane Biophysics Research Institute of Biology V.N. Karazin Kharkiv National University 4 Svobody Sq. Kharkiv61022 Ukraine

BACKGROUND： The possibility of dietary ginger to enhance oxidative stress resistance and to extend life span was studied on Drosophila melanogaster. METHODS： Oxidative stress was induced by a reducing agent dithiothreitol. Experimental groups of male D. melanogaster were cultured on media containing： 1） no additive; 2） dithiothreitol, added into the nutritional mixture to the final concentration of 10 mM; 3） 25 mg of ginger powder g^-1 of the nutritional mixture; and 4） 10 mM ofdithiothreitol and 25 mg of ginger powder g l of the nutritional mixture. The number of alive fruit flies was inspected daily, and mean life span was determined for each experimental group. RESULTS： The addition of dithiothreitol to D. melanogaster nutritional mixture was established to result in an increase in concentration of two markers of oxidative stress conditions （thiobarbituric acid reactive substances as products of lipid peroxidation and carbonylated proteins as products of protein oxidation） in fly tissues. It was followed by significant reduction of mean life span and maximum life span of the last 10% of flies. Plant preparation, being added simultaneously with dithiothreitol, significantly diminished the negative effects of this xenobiotic. In conditions of additional stress load induced by hydrogen peroxide or high temperature, survival of insects treated with dithiothreitol on the background of ginger powder was the highest. CONCLUSIONS： Thus, the presented data give the evidence that ginger preparations can reduce oxidative stress outcomes and significantly increase the life expectancy of fruit flies in stress conditions.

关键词： ginger oxidative stress Drosophila melanogaster

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Thermal radiation and natural convection in a large-scale enclosure heated from below:Building application

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Building Simulation 2021年第3期14卷 681-691页

作者： Stepan A.Mikhailenko Igor V.Miroshnichenko Mikhail A.sheremet Laboratory on Convective Heat and Mass Transfer Tomsk State University634050 TomskRussia Regional Scientific and Educational Mathematical Centre Tomsk State University634050 TomskRussia

A computational research of radiative-convective energy transport in large-scale enclosure with a heat-generating heater under normal room conditions has been *** heater(underfloor heating system)is located at the bottom of the *** the Boussinesq assumption,the control equations have been solved contemporaneously to receive both the velocity fields and temperature *** generate the systems of linear equations using vorticity and stream function,the finite difference technique has been *** developed convective-radiative model has been validated through a comparison with several *** influence of heater size and location,internal surfaces emissivity from 0 to 1,Ostrogradsky number for a wide range from 0 to 5 on Nusselt numbers and both stream function and temperature distributions has been *** results demonstrate that the influence of the thermal radiation on total heat transfer increases with surface emissivity of walls and heater surfaces.

关键词： indoor environment natural convection thermal radiation large-scale cabinet local heater finite difference method

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Weather Induced Quasi-Periodic Motions in Estuaries and Bays:Meteoro-logical Tide

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China Ocean Engineering 2020年第3期34卷 299-313页

作者： LI Chun-yan HUANG Wei WU Ren-hao Alex sheremet College of the Coast and Environment Louisiana State UniversityBaton Rouge 70803USA Virginia Institute of Marine Science College of William and MaryGloucester Pt.23062USA School of Atmospheric Sciences Sun Yat-Sen UniversityZhuhai 519082China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China Engineering School of Sustainable Infrastructure and Environment University of FloridaGainesville FL 32611USA

Influenced by weather, the estuaries and bays often exhibit recurring oscillations in flow and water level similar to astronomical tides. The weather impact however is less regular than tides and more difficult to predict. The spectrum of weather induced motions in estuaries and bays is mostly at the low-frequency end with time scales longer than those of diurnal tides. The repeated weather impact produces meteorological tide: the recurring flood and ebb and flushing of the estuaries and bays but at lower frequencies than those of tides. The variation in weather conditions is quasi-periodic and of large scale nature(~1000-3000 km) because of the alternating low-and high-atmospheric pressure systems of extra-tropical cyclones and anti-cyclones and associated fronts. By examining 40 years of data between Jan. 1, 1977 and Dec. 31, 2016, we identified 1648 frontal events(averaging ~41.2±4.7 per year)influencing the northern Gulf of Mexico for time periods in the spring, fall and winter. The late spring and summer months(May, Jun, July, and August) were not included in the calculation because of much weaker activities involving synoptic weather systems with fronts during these months. It is found that the number of frontal events reached the maximum in Jan. and Dec. while the minimum occurred in April and Sept. It is found that there is an increasing trend of number of fronts over the 40-year period. Our data show that the low pass filtered water level,velocity, and vorticity(velocity shear) all vary in response to the weather and appear as the meteorological tide. The particle excursions of meteorological tides are much larger than those from the astronomical tides. In addition, the irregular nature of the meteorological tide makes the inward flux and outward flux asymmetric in general and thus it has a significant implication to dispersion and transport of waterborne materials. A scaling analysis shows that the meteorological tide generally reaches quasi-steady state;a

关键词： meteorological tide atmospheric fronts particle excursion quasi-steady state northern Gulf of Mexico estuarine exchange flows

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Numerical simulation of MHD natural convection flow in a wavy cavity filled by a hybrid Cu-Al2O3-water nanofluid with discrete heating

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Applied Mathematics and Mechanics(English Edition) 2020年第9期41卷 1345-1358页

作者： C.REVNIC T.GROSAN M.sheremet I.POP Faculty of Pharmacy University of Medicine and PharmacyCluj-Napoca 400012Romania Department of Mathematics Babes-Bolyai UniversityCluj-Napoca 400084Romania Department of Theoretical Mechanics Tomsk State UniversityTomsk 634050Russia

We consider the combined effect of the magnetic field and heat transfer inside a square cavity containing a hybrid nanofluid(Cu-Al2O3-water).The upper and bottom walls of the cavity have a wavy *** temperature of the vertical walls is lower,the third part in the middle of the bottom wall is kept at a constant higher temperature,and the remaining parts of the bottom wall and the upper wall are thermally *** magnetic field is applied under the angleγ,an opposite clockwise *** the numerical simulation,the finite element technique is *** ranges of the characteristics are as follows:the Rayleigh number(10^3≤Ra≤10^5),the hartmann number(0≤ha≤100),the nanoparticle hybrid concentration(ϕAl2O3,ϕCu=0,0.025,0.05),the magnetic field orientation(0≤γ≤2π),and the Prandtl number Pr,the amplitude of wavy cavity A,and the number of waviness n are fixed at Pr=7,A=0.1,and n=3,*** comparison with a reported finding in the open literature is done,and the data are observed to be in very good *** effects of the governing parameters on the energy transport and fluid flow parameters are *** results prove that the increment of the magnetic influence determines the decrease of the energy transference because the conduction motion dominates the fluid *** the Rayleigh number is raised,the Nusselt number is increased,*** moderate Rayleigh numbers,the maximum ratio of the heat transfer takes place for the hybrid nanofluid and then the Cu-nanofluid,followed by the *** nature of motion and energy transport parameters has been scrutinized.

关键词： magnetohydrodynamics natural convection hybrid nanofluid heat transfer bottom heater wavy top and bottom enclosure

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natural convective heat transfer and nanofluid flow in a cavity with top wavywall and corner heater

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Journal of Hydrodynamics 2016年第5期28卷 873-885页

作者： Mikhail A. sheremet Ioan POP hakan F. OZTOP Nidal ABU-haMDEH Department of Theoretical Mechanics Tomsk State University Tomsk Russia Department of Nuclear and Thermal Power Plants Tomsk Polytechnic University Tomsk Russia Department of Applied Mathematics BabesBolyai University Cluj-Napoca Romania Department of Mechanical Engineering Technology Faculty Flrat University Elazig Turkey Mechanical Engineering Department Faculty of Engineering King Abdulaziz University Jeddah Saudi Arabia

A numerical analysis of natural convection of nanofluid in a wavy-walled enclosure with an isothermal comer heater has been carried out. The cavity is heated from the left bottom comer and cooled from the top wavy wall while the rest walls are adiaba- tic. Mathematical model has been formulated using the single-phase nanofluid approach. Main efforts have been focused on the effects of the dimensionless time, Rayleigh number, undulation number, nanoparticle volume fraction and length of comer heaters on the fluid flow and heat transfer inside the cavity. Numerical results have been presented in the form of streamlines, isotherms, velocity and temperature profiles, local and average Nusselt numbers. It has been found that nanoparticle volume fraction essentially affects both fluid flow and heat transfer while undulation number changes significantly only the heat transfer rate.

关键词： wavy cavity natural convection nanofluid comer heater numerical results

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natural convection of an alumina-water nanofluid inside an inclined wavy-walled cavity with a non-uniform heating using Tiwari and Das' nanofluid model

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Applied Mathematics and Mechanics(English Edition) 2018年第10期39卷 1425-1436页

作者： M.A.sheremet R.TRIMBITAS T.GROSAN2 I.POP Laboratory on Convective Heat and Mass Transfer Tomsk State UniversityTomsk 634050Russia Department of Mathematics Babes-Bolyai UniversityCluj-Napoca 400084Romania

The present study is devoted to numerical analysis of natural convective heat transfer and fluid flow of alumina-water nanofluid in an inclined wavy-walled cavity under the effect of non-uniform heating. A single-phase nanofluid model with experimental correlations for the nanofluid viscosity and thermal conductivity has been included in the mathematical model. The considered governing equations formulated in dimensionless stream function, vorticity, and temperature have been solved by the finite difference method. The cavity inclination angle and irregular walls(wavy and undulation numbers)are very good control parameters for the heat transfer and fluid flow. Nowadays, optimal parameters are necessary for the heat transfer enhancement in different practical applications. The effects of the involved parameters on the streamlines and isotherms as well as on the average Nusselt number and nanofluid flow rate have been analyzed. It has been found that the heat transfer rate and fluid flow rate are non-monotonic functions of the cavity inclination angle and undulation number.

关键词： wavy cavity natural convection Al2O3-water nanofluid non-uniform heating numerical result

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A Mathematical Modeling of 3D Cubical Geometry Hypothetical Reservoir under the Effect of nanoparticles Flow Rate,Porosity,and Relative Permeability

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Computer Modeling in Engineering & Sciences 2024年第11期141卷 1193-1211页

作者： Mudasar Zafar hamzah Sakidin Abida Hussain Loshini Thiruchelvam Mikhail sheremet Iskandar Dzulkarnain Roslinda nazar Abdullah Al-Yaari Rizwan Safdar Department of Fundamental and Applied Sciences Universiti Teknologi PETRONASBandar Seri Iskandar32610Malaysia School of Mathematics Actuarial and Quantitative Studies(SOMAQS)Asia Pacific University of Technology and Innovation(APU)Kuala Lumpur57000Malaysia Center for Research in Enhanced Oil Recovery Universiti Teknologi PETRONASBandar Seri Iskandar32610Malaysia Department of Physical and Mathematical Sciences Faculty of ScienceUniversiti Tunku Abdul RahmanPerak31900Malaysia Laboratory on Convective Heat and Mass Transfer Tomsk State UniversityTomsk634050Russia Department of Mathematical Sciences Faculty of Science&TechnologyUniversiti Kebangsaan MalaysiaBangi43600Malaysia Henan Province International Collaboration Lab of Forest Resources Utilization School of ForestryHenan Agricultural UniversityZhengzhou450002China Higher Institution Centre of Excellence(HICoE) Institute of Tropical Aquaculture and Fisheries(AKUATROP)Universiti Malaysia TerengganuKuala Nerus21030Malaysia

This study aims to formulate a steady-state mathematical model for a three-dimensional permeable enclosure(cavity)to determine the oil extraction rate using three distinct nanoparticles,SiO_(2),Al_(2)O_(3),and Fe_(2)O_(3),in unconventional oil *** simulation is conducted for different parameters of volume fractions,porosities,and mass flow rates to determine the optimal oil *** impact of nanoparticles on relative permeability(kr)and water is also *** simulation process utilizes the finite volume ANSYS *** study results showed that when the mass flow rate at the inlet is low,oil recovery goes *** addition,they indicated that silicon nanoparticles are better at getting oil out of the ground(i.e.,oil reservoir)than Al_(2)O_(3)and Fe_(2)O_(3).Most oil can be extracted from SiO_(2),Al_(2)O_(3),and Fe_(2)O_(3)at a rate of 97.8%,96.5%,and 88%,respectively.

关键词： Unconventional reservoir cubical cavity oil recovery rate reservoir engineering mathematical modeling

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Numerical Simulation of Two-Phase Closed Thermosyphon

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Journal of Energy and Power Engineering 2011年第3期5卷 227-232页

作者： G.V. Kuznetsov M.A. Al-Ani M.A. sheremet Institute of Power Engineering National Research Tomsk Polytechnic University Tomsk Russia Faculty of Mechanics and Mathematics Tomsk State University Tomsk Russia

Heat transfer and hydrodynamics of two phase closed thermosyphon （TPCT） is studied using finite difference method of Stream function and vorticity. The mathematical model is formed for both vapor phase and liquid film in a non-dimensional form. The momentum and energy equations as parabolic equations have been solved by means of the locally one-dimensional scheme of A.A. Samarskii. The Poisson equation for the stream function has been approximated on the basis of the discrete scheme ＂cross＂. The obtained system of algebraic equations has been solved by the successive over relaxation method. The effect of the Rayleigh number on the velocity and temperature fields in the domain of interest and on the average Nusselt number at the solid-fluid interfaces is investigated. It was found that increase in the Rayleigh number leads to the increment of both the average Nusselt number and the stream function in the vapor zone.

关键词： Mathematical simulation two-phase thermosyphon conjugate heat transfer hydrodynamics.

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Effects of Storage Duration and Temperature of Human Plasma and Serum on Red Blood Cell Aggregation and Shape

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Open Journal of Biophysics 2013年第4期3卷 212-216页

作者： Yury A. sheremet’ev Alexandra N. Popovicheva Gregory Ya. Levin Federal State Institution Nizhny Novgorod Scientific Research Institute of Traumatology and Orthopedics Ministry of Health of Russia Nizhny Novgorod Russia

Platelet-free plasma of human blood (sodium citrate and EDTA as an anticoagulant) and serum were stored at 4°C, room temperature (25°C) and at 37°C for 24 hours. RBC aggregation decreased after incubation of plasma and serum at 37°C for 4 hours. The RBC shape was changed at the same time: discocytes transformed to echinocytes. Storage of plasma and serum at 4°C and room temperature did not lead to significant alterations of RBC aggregation. The RBC shape did not change in influence of such plasma and serum. The most considerable decrease of RBC aggregation and change of their shapes were observed in the plasma and serum incubated at 37°C for 24 hours. Dilution of incubated plasma by fresh plasma led to consistent restoration of erythrocyte shape and their aggregation.

关键词： In Vitro Time Plasma and Serum Storage Temperature RBC Aggregation Cell Shape

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The Fusability of Erythrocytes as a Method for Evaluating the Instability of Their Membranes

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Open Journal of Biophysics 2013年第3期3卷 198-200页

作者： Yury A. sheremet’ev Aleksandra N. Popovicheva Methun M. Rogozin Gregory Y. Levin Nizhny Novgorod Scientific Research Institute of Traumatology and Ortopedics Nizhny Novgorod Russia

A novel approach to the study of erythrocytes instability based on assessment fusability of their plasma membrane is presented. The fusability of erythrocytes normal blood, stored for 7 days at 4°C, and type 2 patients with diabetes were studied. Human erythrocytes were fused by incubation with La3+ at final concentrations from 50 to 200 μM. Erythrocytes aggregates were incubated at 37°C for 120 min. The fusability of erythrocytes was evaluated using a light microscope. It was shown that La3+ induced extensive fusion of erythrocytes after 7 days of blood storage and erythrocytes of patients with diabetes. Incubation of normal erythrocytes at 37°C for 120 min does not induce cell fusion.

关键词： Erythrocytes Fusability Membrane Instability La3+

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