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A System for Road Pavement Composite Material Deformation

Engineering（科研） 2012年第12期4卷 958-965页

作者： viktor pavlovich basuev Vladimir Nikolaevich Venik Yuriy Konstantinovich Rybin Alexander Karlovich Efa National Research Tomsk Polytechnic University Tomsk Russia Road Construction Company “AVTOBAN” Moscow Russia Tomsky State University of Architecture and Building Tomsk Russia

For a comprehensive experimental evaluation of the material quality, forecast of the properties and parameter change of the bituminous material was made at the time under the impact of external factors, they are subjected to the necessary tests. In the article the automated set “Tomsk-Asphalt-Test” for determining the elastic modulus of the specimens made of bituminous materials was used in road pavements, maximally close to natural conditions of operation of highways of the Siberian region inRussiaare described. The automated set contains: electromechanical, climate, electronic, PC and software subsystem. The operation principle is a short-time deformation of the asphalt specimens;measurement of physical values: the stress, strain, variation of the size line and temperature of the asphalt pavement material test specimen, converting the measured values into electrical signals, their program processing and visualization. The control of testing and viewing results of measurements is carried out in accordance with the menu software subsystem. The results of calculations: the maximum values of vertical load the difference between the maximum horizontal deformation value and the value measured last after specimen of asphalt material loading for each test cycle, the sum of the differences of the horizontal deformation values of the two sensors and modulus of elasticity.

关键词： Road Pavement Composite Asphalt Compression Specimen Deformation Displacement Modulus of Elasticity

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Tumor-Infiltrating Lymphocytes in Primary Tumor and Bone Marrow in Patients with Gastric Cancer and Overweight

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Journal of Pharmacy and Pharmacology 2019年第12期7卷 611-620页

作者： Larissa Nikitichna Bubnovskaya viktor Michailovich Mikhailenko Sergey pavlovich Merentsev Dmitriy Sergeevich Osinsky R.E.Kavetsky Institute of Experimental Pathology Oncology and RadiobiologyNational Academy of Sciences of UkraineVasilkovskaya Str.45Kiev-03022Ukraine City Clinical Oncological Center Verchovynna Str.69Kiev-03115Ukraine

Immune infiltration in human tumors is a key prognostic *** this aspect it has to be noted that the publications concerning the tumor-infiltrating lymphocytes(TILs)under overweight and obesity are limited,especially in the clinical setting in particular concerning gastric *** study has shown that density of TILs consistently associated with body mass index(BMI)and density of cancer-associated adipocytes(CAA)in tumors,decreased significantly in patients with BMI>30 having high density of *** in tumor does not affect this *** with BMI>30 having high density of CAA with slight infiltrating of TILs in tumors demonstrated better overall survival than the same patients with BMI<25 whereas the same patients with BMI<25 but with low density of CAA have shown much longer overall *** of TILs in BM was not affected by both the high density of CAA and level of hypoxia in primary tumor;moreover it has not been associated with BMI as well as patients survival *** the metabolic changes that occur in obese individuals may help to pave the way for more effective treatments for patients with gastric cancer having overweight.

关键词： CD8^+ CD45RO^+-T lymphocytes CAA bone marrow hypoxia BMI

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