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Organo-petrographic and geochemical characteristics of Gurha lignite deposits,Rajasthan,India:Insights into the palaeovegetation,palaeoenvironment and hydrocarbon source rock potential

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Geoscience Frontiers 2020年第3期11卷 965-988页

作者： Runcie Paul Mathews Bhagwan Dsingh vikram partap singh Alpana singh Hukam singh Mahesh Shivanna Suryendu Dutta Vinod A.Mendhe Rimpy Chetia DST-Birbal Sahni Institute of Palaeosciences Lucknow226007India Department of Earth Sciences Indian Institute of Technology BombayMumbai400076India CSIR-Central Institute of Mining and Fuel Research Dhanbad826015India

The sedimentary sequence containing lignite deposits in Gurha quarry of the Bikaner-Nagaur Basin(Rajasthan)has been *** samples from lignite and allied shale horizons were evaluated for petrographical,palynological,palynofacies and organic geochemical inferences,to depict the source flora and to reconstruct the palaeodepositional conditions prevailed during the *** assessment for the hydrocarbon generation potential of these deposits has also been *** results revealed the dominance of huminite macerals and phytoclasts organic matter(OM) indicating the existence of forested vegetation in the vicinity of the depositional site.A relatively high terrigenous/aquatic ratio(TAR) and the carbon preference index(CPI) are also suggesting the contribution of higher plants in the peat ***,the n-alkane distributions,maximizing at n-C17 and n-C29,showed inputs from the algal communities along with the higher plant derived organic *** palynomorphs of the families Onagraceae,Meliaceae,Arecaceae,Rhizophoraceae,Rubiaceae,Ctenolophonaceae, *** with oleanene and ursane types of triterpenoids suggest the contribution from angiosperms source ***,the presence of Araucareaceae and Podocarpaceae pollen grains shows the existence of gymnosperms ***,the presence of tetracyclic diterpanes;demethylated entbeyerane,sandaracopimarane,pimarane,and Kaurane type of compounds confirms the contribution of *** variation in the values of the coefficient of non-equality(H:0.68%-7.56%),the standard deviation(8:0.04%-0.16%) and the coefficient of variability(V:16.10%-46.47%),also shows the heterogeneity in the source organic *** various petrographical indices,palynological entities,and geochemical parameters indicate that the peatforming vegetation was accumulated under a mixed environment and fluctuating hydrological *** interpretation of palynofacies data on APP(Amorphous organ

关键词： Palynofacies Biomarkers Rock-Eval Palaeocene deposits Bikaner-Nagaur Basin

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Effect of using borax decahydrate as nanoparticles additive in blends of spirulina biodiesel/diesel on combustion characteristics and knock intensity

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Clean Energy 2024年第3期8卷 62-78页

作者： Ajay partap singh Puneet singh Gautam Mechanical Engineering Department IIMT University Meerut250001 Uttar PradeshIndia

In this extensive investigation,the impact of borax decahydrate as a fuel additive in a diesel single-cylinder engine was rigorously *** decahydrate was introduced at concentrations of 5,15,25 and 35 g in 500 ml of biodiesel,forming five unique fuel mixtures with conventional diesel:90%diesel+10%spirulina biodiesel(SB10),SB10+1 g borax decahydrate(SB10B1),SB10+3 g borax decahydrate(SB10B3),SB10+5 g borax decahydrate(SB10B5)and SB10+7 g borax decahydrate(SB10B7).The investigation encompassed four diverse loading conditions and yielded insightful ***,at full load,SB10B3 exhibited a higher cylinder peak pressure than diesel,reaching 69.25 *** release rate profiles demonstrated superior efficiency for SB10 at 50%load,with a cumulative heat release rate of 950 J/°CA,which is lower than the 1050 J/°CA of *** intensity(KI)evaluations revealed that,although SB10 and SB10B1 exhibited higher KI than diesel at full load due to elevated peak pressure,SB10B7 showed no knocking across all loads,indicative of reduced in-cylinder *** meticulous numerical analysis emphasizes the potential of borax decahydrate as a catalyst and enhancer,providing valuable insights into the combustion dynamics of these alternative fuel blends and their viability for sustainable and efficient engine *** summary,out of all the blends,SB10B3 could be a potential diesel fuel replacement fuel for compression-ignition engines.

关键词： spirulina biodiesel borax decahydrate diesel engine combustion knock intensity HRR in-cylinder pressure

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CuO–TiO_(2) based self-powered broad band photodetector

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Nano Materials Science 2024年第3期6卷 345-354页

作者： Chiranjib Ghosh Arka Dey Iman Biswas Rajeev Kumar Gupta vikram singh Yadav Ashish Yadav Neha Yadav Hongyu Zheng Mohamed Henini Aniruddha Mondal Department of Physics National Institute of Technology DurgapurWest BengalIndia Department of Physics University of Petroleum&Energy Studies DehradunUttarakhandIndia Babasaheb Bhimrao Ambedkar University Lucknow226031India Center for Advanced Laser Manufacturing(CALM) Shandong University of TechnologyZibo255000PR China School of Physics and Astronomy University of NottinghamNottinghamNG72RDUnited Kingdom

An efficient room-temperature self-powered,broadband(300 nm–1100 nm)photodetector based on a CuO–TiO_(2)/TiO_(2)/p-Si(100)heterostructure is *** CuO–TiO_(2)nanocomposites were grown in a two-zone horizontal tube furnace on a 40 nm TiO_(2)thin film deposited on a p-type Si(100)*** CuO–TiO_(2)/TiO_(2)/p-Si(100)devices exhibited excellent rectification characteristics under dark and individual photoillumination *** devices showed remarkable photo-response under broadband(300–1100 nm)light illumination at zero bias voltage,indicating the achievement of highly sensitive self-powered photodetectors at visible and near-infrared light *** maximum response of the devices is observed at 300 nm for an illumination power of 10 *** response and recovery times were calculated as 86 ms and 78 ms,***,under a small bias,the devices showed a prompt binary response by altering the current from positive to negative under illumination *** main reason behind this binary response is the low turn-on voltage and photovoltaic characteristics of the *** illumination conditions,the generation of photocurrent is due to the separation of photogenerated electron-hole pairs within the built-in electric field at the CuO–TiO_(2)/TiO_(2)*** characteristics make the CuO–TiO_(2)/TiO_(2)broadband photodetectors suitable for applications that require high response speeds and self-sufficient functionality.

关键词： Self-powered CuO–TiO_(2) nanocomposite Broadband photodetector Two-zone horizontal tube furnace Responsivity

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STOCHASTIC SYNCHRONIZATION OF CIRCADIAN RHYTHMS

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Journal of Systems Science & Complexity 2010年第5期23卷 978-988页

作者： RajKumar Brojen singh vikram singh Ram RAMASWAMY Centre for Interdisciplinary Research in Basic Sciences Jamia Milia Islamia New Delhi 110025 India Center for Computational Biology and Bioinformatics School of Information Technology Jawaharlal Nehru University New Delhi 110067 India Center for Computational Biology and Bioinformatics School of Information Technology and School of Physical Sciences Jawaharlal Nehru University New Delhi 110067 India

Models of circadian genetic oscillators involving interlinked feedback processes in molecular level genetic networks in Drosophila melanogaster and Neurospora crassa are studied, and mechanisms whereby synchronization can arise in an assembly of cells are examined. The individual subcellular circadian oscillatory processes are stochastic in nature due to the small numbers of molecules that are involved, and are subject to large fluctuations. The authors investigate and present the simulations of the stochastic dynamics of ensembles of clock-regulating proteins in different nuclei that communicate via ancillary small molecules, environmental parameters, additive cellular noise, or through diffusive processes. The results show that the emergence of collective oscillations is a macroscopic observable which has its origins in the microscopic coupling between distinct cellular oscillators.

关键词： Coupling stochastic dynamics synchrony.

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Cervical cancer:a tale from HPV infection to PARP inhibitors

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Genes & Diseases 2023年第4期10卷 1445-1456页

作者： Minakshi Mann vikram Pratap singh Lalit Kumar Department of Medical Oncology Dr.B.R.A.Institute Rotary Cancer HospitalAll India Institute of Medical SciencesNew Delhi 110029India Department of Oncoanaesthesia and Palliative Medicine Dr.B.R.A.Institute Rotary Cancer HospitalAll India Institute of Medical SciencesNew Delhi 110029India Epigenetics Section Mouse Cancer Genetics ProgramCenter for Cancer ResearchNational Cancer InstituteFrederickMD 21702USA

Globally,cervical cancer(CxCa)ranks 4th common cancer among females and led to 569,847 incidences and 311,365 deaths in 2018.80%of CxCa cases occur due to persistent infection with a high-risk subtype of human papillomavirus(HPV-16 and 18).Smoking,high par-ity,and co-infection with type 2 herpes simplex or HIV are other known risk factors for *** histological subtypes are squamous(70%)and adenocarcinoma(25%).Presently,concur-rent radiation plus cisplatin(CDDP)-based chemotherapy is the standard treatment for CxCa ***,CDDP resistance and toxic side effects limit its efficacy,leading to a poorer response rate and an expected overall survival ranging from 10 to 17.5 *** drug uptake,increased DNA damage repair,increased CDDP inactivation,and overexpressed Bcl-2 or caspase inhibition,are primarily accountable mechanisms for CDDP resistance and improving CDDP’s efficacy remains the major ***(ADP-ribosyl)polymerase-1,an effective mediator of nucleotide excision repair pathway,is involved in DNA repair as well as maintaining genomic stability and is significantly expressed in malignant lymphomas,hepa-tocellular-,cervical-and colorectal carcinoma,which has been approved effective in mainte-nance therapy and may serve as an effective target to enhance CDDP sensitivity in ***,we summarize the etiology and epidemiology of and treatment for CxCa,the mechanism responsible for chemotherapy resistance,PARP inhibitor as a possible therapy for CxCa,and other possible chemotherapeutic options for CxCa treatment.

关键词： Cervical cancer Chemotherapy Cisplatin Disease etiology and histology PARP inhibitors Resistance

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An overview of β-carotene production:Current status and future prospects

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Food Bioscience 2022年第3期47卷 111-120页

作者： Rahul vikram singh Krishika Sambyal Academy of Scientific and Innovative Research (AcSIR) Ghaziabad201002India University Institute of Biotechnology Chandigarh UniversityGharuanPunjabIndia

β-carotene is being used in the food industry as an orange-red pigment for making various food products due to its valuable physical and biological *** use of naturally produced β-carotene has many health benefits rather than the majorly used synthetic production ***,the use of microbial production for β-carotene synthesis can be a promising future for the industries due to its low production cost,use of less manpower,high product yield and eco-friendly production *** present review provides an overview of various β-carotene production methods and their future scope using green industrial production.

关键词： β-Carotene Microbial production Pigment Metabolic engineering Vitamin A

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Controllability of multi-term time-fractional differential systems

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Journal of Control and Decision 2020年第2期7卷 109-125页

作者： vikram singh Dwijendra N.Pandey Department of Mathematics Indian Institute of Technology RoorkeeRoorkee 247667India

In this paper,an abstract multi-term time-fractional differential system is considered and the exact controllability results are *** this theory,we tend to implement the basic tools of fractional calculus and measure of noncompactness to come up with a new set of sufficient conditions for the exact controllability by utilisation of Mönch fixed point ***,an application is given to illustrate the obtained results.

关键词： Fractional calculus exact controllability multi-term time-fractional delay differential system measure of noncompactness

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Aqueous organic redox flow batteries

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Nano Research 2019年第9期12卷 1988-2001页

作者： vikram singh Soeun Kim Jungtaek Kang Hye Ryung Byon Department of Chemistry Korea Advanced Institute of Science and Technology (KAIST)291 Daehak-roYuseong-guDaejeon 34141Republic of Korea Advanced Battery Center KAIST Institute for NanoCentury291 Daehak-roYuseong-guDaejeon 34141Republic of Korea

Redox flow batteries(RFBs)are promising candidates to establish a grid-scale energy storage system for intermittent energy *** the current technology of vanadium RFBs has been widely exploited across the world,the rise in the price of vanadium and its limited volumetric energy density have necessitated the development of new kinds of redox active *** molecules can be used as new and economical redox couples in RFBs to address these *** addition,the redox organic species also provide ample advantages to increase the voltage and solubility,provide multiple numbers of electron transfer,and ensure electrochemical/chemical stability by molecular engineering through simple synthetic *** review focuses on the recent developments in aqueous organic RFBs,including the molecular design and the corresponding cycling performance as these organic redox molecules are employed as either the negolyte or *** strategies for tuning the electrochemical/chemical characteristics of organic molecules have improved their solubility,redox potential cycling stability,and crossover issue across a separating *** also put forward new strategies using nanotechnology and our perspective for the future development of this rapidly growing field.

关键词： redox flow battery redox molecules quinone 2,2,6,6-tetramethylpiperidin-1-yl)oxyl(TEMPO) viologen solubility crossover

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A study of flow interference and heat transfer between two-cylinders at different orientations

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Journal of Ocean Engineering and Science 2021年第3期6卷 248-256页

作者： Shardul vikram singh Praneeti Mitra Pankaj Kumar Department of Mechanical Engineering College of Engineering&TechnologySRM Institute of Science and TechnologyKattankulathur 603203India

A numerical investigation is carried out for the different orientations of a circular cylinder where the upstream cylinder moves with varying anglesα=0˚,30˚,45˚,60˚,90˚with respect to the downstream cylinder in a fixed position at a gap ratio(L/D)of 3 where L is the distance from centre to centre between cylinders and D is the diameter of the *** number(Re),is based on cylinder diameter,is kept constant at 200 for all the cases with air as the working *** vortex shedding formation is analysed when the vortices from the upwind cylinder interact with the downwind cylinder and give impressive flow *** is observed that the drag and lift coefficients increase for both the cylinders with change in angular *** number is calculated with the help of Fast Fourier transformation(FFT)of vorticity magnitude and evaluated for each *** is observed that the effect of upwind cylinder on downwind cylinder is significant forα=30˚,45˚,60˚orientation cases and vortex shedding frequency increases for these ***,the investigation is extending on the laminar forced convection heat transfer performance and variation of Nusselt number for the *** heat transfer is observed for the downwind cylinder atα=45˚.In contrast,the local Nusselt number does not vary much for the cylinders except for the downwind cylinder atα=0˚.

关键词： Tandem cylinder Vortex shedding Nusselt number Strouhal number

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Bacopa monnieri extracts prevent hydrogen peroxide- induced oxidative damage in a cellular model of neuroblastoma IMR32 cells

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Chinese Journal of Natural Medicines 2017年第11期15卷 834-846页

作者： Gaurav Bhatia vikram Dhuna Kshitija Dhuna Manpreet Kaur Jatinder singh Department of Molecular Biology and Biochemistry Guru Nanak Dev University Amritsar-143005 Punjab India Department of Biotechnology DAV College Amritsar-143006 Punjab India Department of Human Genetics Guru Nanak Dev University Amritsar-143005 Punjab India

Neurodegenerative diseases are the consequences of imbalance between the production of oxidative stress and its nullification by cellular defense mechanisms. Hydrogen peroxide(H_2O_2), a precursor of deleterious reactive oxygen species, elicits oxidative stress, resulting in severe brain injuries. Bacopa monnieri is well known for its nerve relaxing and memory enhancing properties. The present study was designed to evaluate the protective effects of extracts from Bacopa monnieri against H_2O_2 induced oxidative stress using a cellular model, neuroblastoma IMR32 cell line. The protective potential of methanolic, ethanolic, and water extracts of B. monnieri(BM-MEx, BM-EEx, and BM-WEx) was evaluated using MTT assay. Although, all the B. monnieri extracts were found to protect cells against H_2O_2-mediated stress but BM-MEx showed significantly greater protection. UPLC analysis of BM-MEx revealed various polyphenols, including quercetin, catechin, umbelliferone, and caffeic acid predominance. Further, BM-MEx was found to possess considerable greater neuroprotective potential in comparison to the standard polyphenols such as quercetin, catechin, umbelliferone, and caffeic acid. The levels of antioxidant enzymes were significantly elevated after the pretreatment of BM-MEx and quercetin. The expression levels of oxidative stress markers, such as NF200, HSP70, and mortalin, were significantly alleviated after the pretreatment of BM-MEx as shown by immunofluorescence and RT-PCR. In conclusion, the present study demonstrated the protective effects of BM-MEx, suggesting that it could be a candidate for the development of neuropathological therapeutics.

关键词： Antioxidant enzymes Bacopa monnieri H2O2 IMR32 neuroblastoma NF200 HSP70 Mortalin

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