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Biorenewable materials for water remediation: The central role of cellulose in achieving sustainability

Journal of Bioresources and Bioproducts 2024年第3期9卷 253-282页

作者： Kirti Mishra Samarjeet singh Siwal Thandiwe Sithole Nirankar singh Phil Hart vijay Kumar Thakur Department of Chemistry M.M.Engineering CollegeMaharishi Markandeshwar(Deemed to be University)Haryana 133207India Department of Chemical Engineering University of JohannesburgDoornfontein 2088South Africa Biorefining and Advanced Materials Research Center Scotland’s Rural CollegeEdinburgh EH93JGUnited Kingdom Renewable and Sustainable Energy Research Centre Technology Innovation InstituteAbu Dhabi 9639United Arab Emirates School of Engineering University of Petroleum&Energy StudiesDehradun 248007India

As the population increases and manufacturing grows,greenhouse gas and other harmful emissions *** with chemicals such as dyes,pesticides,pharmaceuticals,oil,heavy metals or radionuclides,wastewater purification has become an urgent *** technologies exist that can remove these contaminants from wastewater sources,but they often demand high energy and/or high cost,and in some cases produce contaminant laden sludge that requires safe *** need for methods which are less capital intensive,less operationally costly and more environmentally friendly is ***-based materials have emerged as promising candidates for wastewater treatment due to their renewability,low cost,biodegradability,hydrophilicity,and antimicrobial *** this review article,we focussed on developing sustainable and biodegradable cellulose-based materials for wastewater *** article deals with cellulose-based materials’scope and their conversion into valuable products like hydrogel,aerogel,cellulose composites,and *** cellulose-based materials have no harmful environmental impact and are *** modified cellulose-based materials applying as membrane,adsorbent,sorbent,and beads to purify the wastewater were ***,the challenges and future prospects of cellulose-based materials for wastewater treatment were considered,emphasizing their potential to be sustainable and eco-friendly alternatives to traditional materials used in wastewater treatment.

关键词： Cellulose Wastewater treatment Hydrogel Nanocrystal Cellulose membrane

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Cardioprotective activity of alcoholic extract of Tinospora cordifolia (Willd.) Miers in calcium chloride-induced cardiac arrhythmia in rats

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The Journal of Biomedical Research 2011年第4期25卷 280-286页

作者： Ashish Kumar Sharma Kunal Kishore Divya Sharma B.P Srinivasan Shyam Sunder Agarwal Ashok Sharma Santosh Kumar singh Samir Gaur vijay singh jatav Department of Pharmacology Gyan Vihar School of PharmacySuresh Gyan Vihar UniversityJagatpuraJaipur (Rajasthan)302025India Delhi Institute of Pharmaceutical Sciences & Research Department of PharmacologyPushpviharSector Ⅲ.New Delhi 110017India

The present study investigated the antiarrhythmic activity of alcoholic extract of Tinospora cordifolia （T. cordifolia） in CaCl2 induced arrhythmia. CaCl2 （25 mg/kg） was administered by intravenous infusion （iv） to produce arrhythmia in rats. The animals were then treated with T. cordifolia extract （150, 250, and 450 mg/kg） and verapamil （5 mg/kg,iv）. Lead II electrocardiogram was monitored. Plasma calcium, sodium and potassium levels were measured. In CaCl2 induced arrhythmia, heart rate was decreased by 41.10%, T. cordifolia at 150, 300, and 450 mg/kg decreased the heart rate by 26.30%, 29.16%, and 38.29%, respectively, and verapamil reduced the heart rate by 9.70% compared to the normal group. The PQRST waves were normalized and atrial and ventricular fibrillation was controlled in rats treated with verapamil and T. cordifolia. CaCl2 increased calcium and sodium levels and decreased potassium levels in blood. T. cordifolia dose-dependently decreased calcium and sodium levels and increased potassium levels. Hence, T. cordifolia can be used in antiarrhythmic clinical settings and beneficial in atrial and ventricular fibrillation and flutter and may be indicated in ventricular tachyarrhythmia.

关键词： Tinospora cordifolia arrhythmia cardioprotection.

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Random Amplification Polymorphic DNA and Agro-Morphological Traits-Based Fingerprinting for Detection of Genetic Divergence in Indian Black Rice

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Rice science 2024年第4期31卷 366-370,I0004-I0014页

作者： Manisha SHARMA Dhananjay RATURI vijay Rani RAJPAL Manju CHAUDHARY Soom Nath RAINA Apekshita singh Amity Institute of Biotechnology Amity University Uttar PradeshSector-125UP 201313India Department of Botany Hansraj CollegeUniversity of DelhiDelhi 110007India

In this study, 32 black rice genotypes spanning diverse geographies in India were evaluated at both phenotypic and DNA sequence levels to gain insights into their genetic makeup. Significant variations were observed f... 详细信息

关键词： Indian Morphological Traits

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Methyl-salicylate:A surveillance system fortriggering immunity in neighboring plants

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Journal of Integrative Plant Biology 2024年第2期66卷 163-165页

作者： Saumya Jaiswal Durgesh Kumar Tripathi Ravi Gupta JingHe Zhong-Hua Chen vijay Pratap singh Plant Physiology Laboratory Department of Botany C.M.P.Degree CollegeA Constituent Post Graduate College ofUniversity of AllahabadPrayagraj 211002India Crop Nanobiology and Molecular Stress Physiology LabAmity Institute of Organic Agriculture Amity University UttarPradeshNoida 201313India College of General Education Kookmin UniversitySeoul 02707South Korea School of Science Western Sydney UniversitySydney 2751New South WalesAustralia Hawkesbury Institute for the Environment Western SydneyUniversitySydney 2751New South WalesAustralia

Plant behavioral actions have been one of the major topicsof research in plant biology and *** actionsfrom plants are determined by their instant structural andphysical reactions to the circumstances(Bouwmeester et al.,2019).Upon sensing abiotic factors such as salinity,flooding,high temperature,drought,plants make suitable changes intheir physiology and behavior to survive such harsh conditions.

关键词： immunity neighboring salinity

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Involvement of adenosine and standardization of aqueous extract of garlic(Allium sativum Linn.)on cardioprotective and cardiodepressant properties in ischemic preconditioning and myocardial ischemia-reperfusion induced cardiac injury

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The Journal of Biomedical Research 2012年第1期26卷 24-36页

作者： Ashish Kumar Sharma Arshee Munajjam Bhawna Vaishnav Richa Sharma Ashok Sharma Kunal Kishore Akash Sharma Divya Sharma Rita Kumari Ashish Tiwari Santosh Kumar singh Samir Gaur vijay singh jatav Barthu Parthi Srinivasan Shyam Sunder Agarwal Department of Pharmacology Gyan Vihar School of PharmacySuresh Gyan Vihar University Department of Pharmacology Delhi Institute of Pharmaceutical Sciences & Research

The present study investigated the effect of garlic （Allium sativum Linn.） aqueous extracts on ischemic pre- conditioning and ischemia-reperfusion induced cardiac injury, as well as adenosine involvement in ischemic pre- conditioning and garlic extract induced cardioprotection. A model of ischemia-reperfusion injury was established using Langendorff apparatus. Aqueous extract of garlic dose was standardized （0.5%, 0.4%, 0.3%, 0.2%, 0.1%, 0.07%, 0.05%, 0.03%, 0,01%）, and the 0.05% dose was found to be the most effective. Higher doses （more than 0.05%） were highly toxic, causing arrhythmia and cardiodepression, whereas the lower doses were ineffective. Garlic exaggerated the cardioprotective effect of ischemic preconditioning. The cardioprotective effect of ischemic preconditioning and garlic cardioprotection was significantly attenuated by theophylline （1,000 ~tmol/L） and 8-SPT （10 mg/kg, i.p.） and expressed by increased myocardial infarct size, increased LDH level, and reduced nitrite and adenosine levels. These findings suggest that adenosine is involved in the pharmacological and molecular mechanism of garlic induced cardioprotection and mediated by the modulation of nitric oxide.

关键词： Allium sativum Linn. ischemic preconditioning cardioprotection adenosine nitrite

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高速火焰喷涂VC-CuNiCr涂层的耐腐蚀性能

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Journal of Central South University 2024年第5期31卷 1385-1397页

作者： singh Vikrant BANSAL Anuj SINGLA Anil Kumar KUMAR vijay Sant Longowal Institute of Engineering and Technology Longowal Sangrur 148106India Industrial and Production Engineering Department Dr B R Ambedkar National Institute of TechnologyJalandhar 144011India

本研究采用高速火焰喷涂(HVOF)沉积技术,将碳化钒(VC)和铜镍铬(CuNiCr)复合涂层应用于SS316不锈钢上,以解决不锈钢在海洋环境中的腐蚀问题。在室温环境下,在3.5%氯化钠溶液中进行电化学腐蚀,通过扫描电子显微镜(SEM)和能量色散光谱(EDS... 详细信息

本研究采用高速火焰喷涂(HVOF)沉积技术,将碳化钒(VC)和铜镍铬(CuNiCr)复合涂层应用于SS316不锈钢上,以解决不锈钢在海洋环境中的腐蚀问题。在室温环境下,在3.5%氯化钠溶液中进行电化学腐蚀,通过扫描电子显微镜(SEM)和能量色散光谱(EDS)对有涂层和未覆涂层样品的表面形貌进行检测。结果表明,涂层内由铜(Cu)、镍(Ni)和铬(Cr)组成的金属间黏合剂在氯化钠介质的影响下发生变质,从而导致出现衬底间的局部点蚀现象。有趣的是,在涂层配方中加入碳化钒(VC)显著地增强了表面的耐腐蚀性能,从而阻止了密闭腐蚀凹坑的出现。在不同类的涂层中,加入VC的效果最好,最小的腐蚀速率为72.38×10^(-3)mm/a,相比之下,SS316基底的腐蚀速率最快。

关键词：高速火焰喷涂碳化钒铜镍铬电化学腐蚀氯化钠溶液

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Sitagliptin,sitagliptin and metformin,or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats

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The Journal of Biomedical Research 2012年第3期26卷 200-210页

作者： Ashish Kumar Sharma Akash Sharma Rita Kumari Kunal Kishore Divya Sharma Bharthu Parthsarthi Srinivasan Ashok Sharma Santosh Kumar singh Samir Gaur vijay singh jatav Prashant Sharma Varnika Srivastava Sneha Joshi Megha Joshi Prashant Kumar Dhakad Davender singh Kanawat Akanksha Mishra Anil Sharma Dharmendra singh Ravinder Pal singh Himmat singh Chawda Rambir singh Sachin Kumar Raikwar Muneem Kumar Kurmi Pankaj Khatri Ashutosh Agarwal Arshee Munajjam Department of Pharmacology Gyan Vihar School of PharmacySuresh Gyan Vihar UniversityJagatpuraJaipur(Rajasthan)302025India Department of Pharmacology Delhi Institute of Pharmaceutical Sciences&ResearchPushpviharNew Delhi 110017India Department of Pharmacology Kota Collage of PharmacyRIICO Industrial AreaRanpurKota(Rajasthan)Pincode 302025India

Diabetic neuropathies are a family of nerve disorders caused by diabetes. Symptoms of the disease include nerve palsy, mononeuropathy, mononeuropathy multiplex, diabetic amyotrophy, painful polyneuropathy, autonomic neu- ropathy, and thoracoabdominal neuropathy. In this study, type 2 diabetes in rats was induced with nicotinamide- streptozotocin. Drug treatment was initiated on the d 15, with the combination regimen of metformin, pioglitazone and glimipiride or metformin and sitagliptin or sitagliptin, amitriptyline and sitagliptin and led to significantly im- proved glycemic control, increased grip strength and paw jumping response on d 21, 28 and 35 （P 〈 0.001）. Signif- icant increases in blood protein levels and decreases in urinary protein levels were observed in the animals treated with the different regimens on d 21, 28 and 35 （P 〈 0.001）. Combined treatment of streptozotocin and nicotinamide caused marked degeneration of nerve cells, while administration of metformin and sitagliptin showed tissue regen- eration and no body weight gain. In conclusion, treatment with sitagliptin and sitagliptin combined with metformin or amitriptyline results in no body weight gain, but causes an increase in grip strength and pain sensitivity, exhibits neural protection, and reverses the alteration of biochemical parameters in rats with streptozotocin-nicotinamide induced type 2 diabetes.

关键词： diabetic neuropathy nicotinamide-streptozotocin metformin pioglitazone glimipiride sitagliptin amitriptyline

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Cellulose-based smart materials:Novel synthesis techniques,properties,and applications in energy storage and conversion devices

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Electron 2024年第2期2卷 159-195页

作者： Pariksha Bishnoi Samarjeet singh Siwal vijay Kumar Thakur Department of Chemistry M.M.Engineering CollegeMaharishi Markandeshwar(Deemed to be University)Mullana-AmbalaHaryanaIndia Biorefining and Advanced Materials Research Center Scotland's Rural College(SRUC)EdinburghUK 3School of WaterEnergy and EnvironmentCranfield UniversityCranfieldUK

There has been a significant scope toward the cutting-edge in-vestigations in hierarchical carbon nanostructured electrodes originating from cellulosic materials,such as cellulose nanofibers,available from natural cellulose and bacterial *** of energy storage systems(ESSs)are typically established upon inorganic/metal mixtures,carbonaceous implications,and petroleum-derived hydrocarbon ***,these conventional substances may need help fulfilling the ever-increasing needs of *** has grown significantly as an impressive 1D element due to its natural availability,eco-friend-liness,recyclability,structural identity,simple transformation,and dimensional ***,in this review article,we have discussed the role and overview of cellulose-based hydrogels in ***,the extraction sources and solvents used for dissolution have been dis-cussed in ***,the properties(such as self-healing,trans-parency,strength and swelling behavior),and applications(such as flexible batteries,fuel cells,solar cells,flexible supercapacitors and carbon-based derived from cellulose)in energy storage devices and conclusion with existing challenges have been updated with recent findings.

关键词： batteries cellulose-based materials energy storage devices fuel cells hydrogels supercapacitors

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Whispered Tuning: Data Privacy Preservation in Fine-Tuning LLMs through Differential Privacy

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Journal of Software Engineering and Applications 2024年第1期17卷 1-22页

作者： Tanmay singh Harshvardhan Aditya vijay K. Madisetti Arshdeep Bahga School of Computer Science Engineering & Technology Bennett University Greater Noida India School of Cybersecurity and Privacy Georgia Institute of Technology Atlanta USA Cloudemy Technology Labs Chandigarh India

The proliferation of Large Language Models (LLMs) across various sectors underscored the urgency of addressing potential privacy breaches. Vulnerabilities, such as prompt injection attacks and other adversarial tactics, could make these models inadvertently disclose their training data. Such disclosures could compromise personal identifiable information, posing significant privacy risks. In this paper, we proposed a novel multi-faceted approach called Whispered Tuning to address privacy leaks in large language models (LLMs). We integrated a PII redaction model, differential privacy techniques, and an output filter into the LLM fine-tuning process to enhance confidentiality. Additionally, we introduced novel ideas like the Epsilon Dial for adjustable privacy budgeting for differentiated Training Phases per data handler role. Through empirical validation, including attacks on non-private models, we demonstrated the robustness of our proposed solution SecureNLP in safeguarding privacy without compromising utility. This pioneering methodology significantly fortified LLMs against privacy infringements, enabling responsible adoption across sectors.

关键词： NLP Differential Privacy Adversarial Attacks Informed Decisions

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Barriers in early detection of colorectal cancer and exploring potential solutions

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World Journal of Clinical Oncology 2024年第7期15卷 811-817页

作者： Maryam Aleissa Ernesto Raul Drelichman vijay K Mittal Jasneet singh Bhullar Department of Surgery Ascension Providence HospitalMichigan State University College of Human MedicineSouthfieldMI 48075United States College of Medicine Princess Norah University HospitalRiyadh 11564Saudi Arabia

This editorial discusses the literature review article by Tonini and Zanni,the paper was published in January 2024,and the authors provided very interesting conclusions regarding existing barriers to the early diagnosis of colon *** cancers do not have identifiable precursors,or there are currently no screening tests to find ***,these cancers do not have preventive screening *** detection is crucial for reducing mortality rates by identifying cancer at an earlier stage through screening,as opposed to no *** cancer develops from precancerous lesions,which can be detected early and potentially prevented and *** detection leads to improved survival rates,decreased complications,and reduced healthcare *** editorial provides a brief description of the biology of colon cancer,emphasizing the contrast in outcomes between early detection and late *** also describe screening programs around the globe and examine the barriers in each ***,we explore potential future solutions to enhance inclusion in screening programs and improve patient compliance.

关键词： Colon cancer Rectal cancer Early detection

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