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Annular Gas Distributor for a Swirling Fluidized Bed

材料科学与工程（中英文版） 2011年第4期5卷 431-438页

作者： Mohd Faizal Mohideen Suzairin Md Seri vijay R. Raghavan Faculty of Mechanical ＆ Manufacturing Engineering Univ. Tun Hussein Onn Malaysia Batu Pahat 86400 Johor Malaysia Department of Mechanical Engineering Universiti Teknologi PETRONAS Tronoh 31750 Perak Malaysia

Fluidized bed technology serves many purposes in industry which involves interaction between solid particles with gases and liquids. The most vital component in a fluidized bed system is the distributor which governs the rate of solid-fluid contact as well as the fluidization quality. One of the relatively new types of distributor is the annular distributor. The aim of the present work is to evaluate experimentally the performance of several configurations of the annular distributor by considering the pressure drop, ?p, as the performance criterion. The distributor has been studied by varying the number of blades (60 blades and 30 blades), varying the centre bodies in the bed (cone and cylinder) and by using different over-lapping blade lengths (O/L) while increasing the fluidizing gas velocity. The main findings show that the annular distributor exhibits similar characteristics as multi-orifice distributor as reported by Geldart and Baeyens. The distributor pressure drop increased exponentially with superficial air velocity, with little influence from the type of centre body used. On the other hand, the number of blades affects the distributor pressure drop significantly. The most desirable feature in fluidized beds - having low distributor pressure drop yet having good fluidization quality has been successfully achieved. The distributor to bed pressure drop ranging from 0.2 to 0.5 has been obtained in the current work, which is particularly low and ideal to reduce total energy consumption of the system. In conclusion, the annular distributor is found to be ideal for batch processing, particularly with low bed heights.

关键词：环形分配器气体分布流化床旋流床层压降性能标准经销商技术服务

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艾滋病合并马尔尼菲篮状菌病抗逆转录病毒治疗启动时机的多中心前瞻性随机对照研究

艾滋病合并马尔尼菲篮状菌病抗逆转录病毒治疗启动时机的多中心前...

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中华中医药学会防治艾滋病分会2021年学术年会

作者：秦圆圆周怡宏鲁雁秋刘敏袁婧聂静敏秦英梅蒋忠胜周国强田群蓝珂周泱杨欣平何凯茵刘俊 vijay Harypursat 陈耀凯重庆市公共卫生医疗救治中心南宁市第四人民医院柳州市人民医院长沙市第一医院桂林市第三人民医院广西壮族自治区龙潭医院深圳市第三人民医院云南省传染病医院广州市第八人民医院昆明市第三人民医院

目的比较艾滋病合并马尔尼菲篮状菌病患者早启动抗逆转录病毒治疗或晚启动抗病毒治疗的安全性与预后。方法筛选14家临床中心2019年1月至2020年12月艾滋病合并马尔尼菲篮状菌病患者共206例,随机分为早启动抗逆转录病毒治疗组(2周内启动... 详细信息

目的比较艾滋病合并马尔尼菲篮状菌病患者早启动抗逆转录病毒治疗或晚启动抗病毒治疗的安全性与预后。方法筛选14家临床中心2019年1月至2020年12月艾滋病合并马尔尼菲篮状菌病患者共206例,随机分为早启动抗逆转录病毒治疗组(2周内启动抗逆转录病毒治疗)及晚启动抗逆转录病毒治疗组(2周后启动抗逆转录病毒治疗)。采用卡方检验、logistic多因素回归及Cox多因素回归对两组间结局进行比较。结果共181名符合条件患者纳入分析,其中早启动组80例,晚启动组101例。晚启动组较早启动组之间48周内全因死亡率与艾滋病定义性事件发生率均无统计学差异(2.5%vs.8.9%,aHR=2.605,95%CI:0.301-22.538;1.3%vs. 3.0%, aHR=4.437, 95%CI:0.470-41.870)。且在CD4+计数<50细胞/mm3的患者中死亡率与艾滋病定义性事件发生率亦未见显著差异(2.7%vs.8.5,aHR=2.928, 95%CI:0.345-24.867;1.4%vs. 5.3%, aHR=4.217, 95%CI:0.425-41.880)。试验期间仅有1例患者(早启动组)发生免疫重建炎症综合征。共22名患者发生3-4级不良事件,两组患者3-4级不良事件发生率未见显著统计学差异(10.0%vs.13.9,aOR=1.18895%CI:0.394-3.586)。结论在48周的观察期内,2周内或2周后启动抗逆转录病毒治疗的艾滋病合并马尔尼菲篮状菌病患者预后相当,且严重不良事件发生率相似。早启动抗逆转录病毒治疗对艾滋病合并马尔尼菲篮状菌病患者的预后或不良事件的发生无负面影响。

关键词：艾滋病马尔尼菲篮状菌病抗逆转录病毒治疗

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Sitagliptin,sitagliptin and metformin,or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats

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The Journal of Biomedical Research 2012年第3期26卷 200-210页

作者： Ashish Kumar Sharma Akash Sharma Rita Kumari Kunal Kishore Divya Sharma Bharthu Parthsarthi Srinivasan Ashok Sharma Santosh Kumar Singh Samir Gaur vijay Singh Jatav Prashant Sharma Varnika Srivastava Sneha Joshi Megha Joshi Prashant Kumar Dhakad Davender Singh Kanawat Akanksha Mishra Anil Sharma Dharmendra Singh Ravinder Pal Singh Himmat Singh Chawda Rambir Singh Sachin Kumar Raikwar Muneem Kumar Kurmi Pankaj Khatri Ashutosh Agarwal Arshee Munajjam Department of Pharmacology Gyan Vihar School of PharmacySuresh Gyan Vihar UniversityJagatpuraJaipur(Rajasthan)302025India Department of Pharmacology Delhi Institute of Pharmaceutical Sciences&ResearchPushpviharNew Delhi 110017India Department of Pharmacology Kota Collage of PharmacyRIICO Industrial AreaRanpurKota(Rajasthan)Pincode 302025India

Diabetic neuropathies are a family of nerve disorders caused by diabetes. Symptoms of the disease include nerve palsy, mononeuropathy, mononeuropathy multiplex, diabetic amyotrophy, painful polyneuropathy, autonomic neu- ropathy, and thoracoabdominal neuropathy. In this study, type 2 diabetes in rats was induced with nicotinamide- streptozotocin. Drug treatment was initiated on the d 15, with the combination regimen of metformin, pioglitazone and glimipiride or metformin and sitagliptin or sitagliptin, amitriptyline and sitagliptin and led to significantly im- proved glycemic control, increased grip strength and paw jumping response on d 21, 28 and 35 （P 〈 0.001）. Signif- icant increases in blood protein levels and decreases in urinary protein levels were observed in the animals treated with the different regimens on d 21, 28 and 35 （P 〈 0.001）. Combined treatment of streptozotocin and nicotinamide caused marked degeneration of nerve cells, while administration of metformin and sitagliptin showed tissue regen- eration and no body weight gain. In conclusion, treatment with sitagliptin and sitagliptin combined with metformin or amitriptyline results in no body weight gain, but causes an increase in grip strength and pain sensitivity, exhibits neural protection, and reverses the alteration of biochemical parameters in rats with streptozotocin-nicotinamide induced type 2 diabetes.

关键词： diabetic neuropathy nicotinamide-streptozotocin metformin pioglitazone glimipiride sitagliptin amitriptyline

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瑞芬太尼能够取代氧化亚氮用于地氟烷和芬太尼麻醉的门诊骨科手术吗？

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麻醉与镇痛 2009年第1期5卷 55-62页

作者： Donald M. Mathews vijay Gaba Bledi Zaku George G. Neuman 刘宽智(译) 刘克玄(校) 陈秉学(校) Department of Anesthesiology St. Vincent Catholic Medical Centers St. Vincent's Manhattan and New York Medical College Valhalla New York 不详

背景手术中使用氧化亚氮（N2O）可能导致多种不良反应和毒性反应。瑞芬太尼与氧化亚氮有相似的特性，包括：降低挥发性麻醉药的MAC、镇痛以及停用后药效快速消失。我们比较了在门诊骨科手术采用地氟烷和芬太尼麻醉的患者中，添加临床等... 详细信息

背景手术中使用氧化亚氮（N2O）可能导致多种不良反应和毒性反应。瑞芬太尼与氧化亚氮有相似的特性，包括：降低挥发性麻醉药的MAC、镇痛以及停用后药效快速消失。我们比较了在门诊骨科手术采用地氟烷和芬太尼麻醉的患者中，添加临床等效剂量的氧化亚氮或瑞芬太尼对手术后转归的影响。方法70例行门诊骨科手术的患者入选。其中35例吸入66％的N2O，其余35例接受静脉注射0．085ug·kg^-1·min^-1的瑞芬太尼。所有患者均复合使用地氟烷并逐步增加剂量至脑电双频指数（BIS）为50，同时静脉注射芬太尼。测定的主要转归指标为患者在语言刺激下苏醒的时间，次要转归指标包括：神经心理测验、定向力恢复时间、血流动力学指标、疼痛和恶心的视觉模拟评分、出院时间以及满意度评分。此外还观察地氟烷的呼气末平均浓度和芬太尼效应室浓度。结果语言唤醒时间的中位数（四分位距）：瑞芬太尼组为3．0分钟（3．0—5．0分钟），N2O组的为4．6分钟（3．0～8．1分钟），两组间差异无统计学意义。瑞芬太尼组的定向力恢复时间为6．0分钟（5．0—8．5分钟）明显短于N2O组8．0分钟（5．0～12．8分钟）。两组患者地氟烷和芬太尼的使用剂量、神经心理测试以及其他测定的转归指标均无显著差异。结论本研究表明在地氟烷和芬太尼麻醉期间，0．085ug·kg^-1·min^-1的瑞芬太尼能够代替66％N2O，并且不改变患者的临床转归。

关键词：挥发性麻醉药瑞芬太尼氧化亚氮骨科手术地氟烷门诊手术后转归视觉模拟评分

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Kali Linux高级渗透测试

Kali Linux高级渗透测试

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作者： (印)维杰·库马尔·维卢(vijay Kumar Velu)，(加)罗伯特·贝格斯(Robert Beggs)

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致辞

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中国对外贸易 2017年第8期 17-17页

作者： vijay Gokhale

在金砖国家领导人第九次峰会举办前夕，中国国际贸易促进委员会的《中国对外贸易》杂志特别制作专刊。对此，我表示非常赞赏。我们支持中国作为本届金砖国家峰会轮值主席国，并期待在共同努力下，此次峰会富有成效并取得圆满成功。我相... 详细信息

在金砖国家领导人第九次峰会举办前夕，中国国际贸易促进委员会的《中国对外贸易》杂志特别制作专刊。对此，我表示非常赞赏。我们支持中国作为本届金砖国家峰会轮值主席国，并期待在共同努力下，此次峰会富有成效并取得圆满成功。我相信，在2016年印度果阿召开的金砖国家领导人第八次会晤成果的基础上，在今年轮值主席国中国的推动下金砖合作将继续深化。

关键词：《中国对外贸易》中国国际贸易促进委员会国家领导人致辞峰会

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Next-generation sequencing in clinical virology: Discovery of new viruses

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World Journal of Virology 2015年第3期4卷 265-276页

作者： Sibnarayan Datta Raghvendra Budhauliya Bidisha Das Soumya Chatterjee Vanlalhmuaka vijay Veer Molecular Virology Laboratory Defence Research Laboratory (DRDO)

Viruses are a cause of significant health problem world-wide, especially in the developing nations. Due to different anthropological activities, human populations are exposed to different viral pathogens, many of which emerge as outbreaks. In such situations, discovery of novel viruses is utmost important for deciding prevention and treatment strategies. Since last century, a number of different virus discovery methods, based on cell culture inoculation, sequence-independent PCR have been used for identification of a variety of viruses. However, the recent emergence and commercial availability of nextgeneration sequencers(NGS) has entirely changed the field of virus discovery. These massively parallel sequencing platforms can sequence a mixture of genetic materials from a very heterogeneous mix, with high sensitivity. Moreover, these platforms work in a sequenceindependent manner, making them ideal tools for virus discovery. However, for their application in clinics, sample preparation or enrichment is necessary to detect low abundance virus populations. A number of techniques have also been developed for enrichment or viral nucleic acids. In this manuscript, we review the evolution of sequencing; NGS technologies available today as well as widely used virus enrichment technologies. We also discuss the challenges associated with their applications in the clinical virus discovery.

关键词： PCR Next-generation sequencers Virus discovery Sequence-independent single-primer amplification Virus discovery based on cDNA-AFLP Rolling circle amplification Metagenomics

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单组分化学浆液对浆纱性能的影响

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国际纺织导报 2022年第7期50卷 4-5页

作者： S.Sarwale V.S.Shivankar A.Karande A.M.Daberao 王燕斌(译) 孟粉叶(校) 希尔普尔SVKM NMIMS大学、工程与技术管理学院纺织功能中心印度不详

该研究旨在了解单组分化学浆液对上浆参数及其性能的影响。比较了原纱、传统浆纱和该研究浆纱的性能,并进行了各种测试,如断裂强度和伸长率、耐磨性、纱线摩擦性能、条干均匀度和纱线毛羽等的测试。结果表明,与原纱和传统浆纱相比,经单... 详细信息

该研究旨在了解单组分化学浆液对上浆参数及其性能的影响。比较了原纱、传统浆纱和该研究浆纱的性能,并进行了各种测试,如断裂强度和伸长率、耐磨性、纱线摩擦性能、条干均匀度和纱线毛羽等的测试。结果表明,与原纱和传统浆纱相比,经单组分化学浆上浆所得的纱线强度高、伸长率低。同时还发现,经该文浆料上浆所得纱线具有较好的耐磨性。研究该项目的主要目的是提高纱线的织造能力,减少毛羽,提高纱线的强度。

关键词：单组分化学浆液纱线性能上浆参数

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Management of enterocutaneous fistulae:A 10 years experience

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World Journal of Gastrointestinal Surgery 2010年第7期2卷 242-246页

作者： Deepa Taggarshe Daniel Bakston Michael Jacobs Alasdair McKendrick vijay K Mittal Department of Surgery Providence Hospital and Medical Centers16001 West Nine Mile RoadSouthf ieldMI 48075United States

AIM:To compare the outcomes of conservative vs surgical treatment of enterocutaneous fistulae(ECF) in a community teaching hospital over a ***:All cases of ECF between 1997 and 2007 were reviewed for management ***:Of the 83 patients with ECF,60(72%) were ***-six patients(79.5%) were treated initially with conservative *** patients failed to respond to conservative treatment and required later(secondary) exploration;this group consisted of an equal number of low vs high output ***(20.5%) patients underwent initial(primary) def initivesurgery secondary to anastomotic leak and *** procedures included resection of ECF with anastomosis(24),exclusion(6) and direct-drainage(4).No signif icant difference was seen in the recurrence rate for conservative(10%) vs operative-treatment(20%).role as an initial management in both low and high output *** selective cases only,early primary exploration is recommended.

关键词： Low-output High-output Enterocutaneous fistulae

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<i>Helicobacter</i>infection decreases basal colon inflammation, but increases disease activity in experimental IBD

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Open Journal of Gastroenterology 2013年第3期3卷 177-189页

作者： Christopher P. Monceaux Traci L. Testerman Moheb Boktor Paul Jordan Patrick Adegboyega David J. McGee Merilyn H. Jennings Courtney P. Parker Shelly Gupta Ping Yi vijay C. Ganta Haidy Galous Kenneth Manas J. Steven Alexander Department of Gastroenterology and Hepatology LSU Health Shreveport Shreveport USA Department of Microbiology and Immunology LSU Health Shreveport Shreveport USA Department of Molecular and Cellular Physiology LSU Health Shreveport Shreveport USA Department of Pathology LSU Health Shreveport Shreveport USA

Background: Helicobacter species are best known for their roles in the pathology of gastritis;however, several Helicobacter species also colonize the intestine, and less is known about effects of Helicobacter on the development of intestinal inflammation. To evaluate contributions of Helicobacter in inflammatory bowel disease, we investigated whether and how pre-existing intestinal colonization would affect disease severity and biomarkers of inflammation in experimental IBD. Materials and Methods: Mice were infected with H. muridarum 2 weeks prior to induction of colitis mediated by 3% dextran sulfate (DSS). Disease activity index, stool blood and consistency, colon length, myeloperoxidase, histopathology, blood and lymphatic vessels, and numbers of dilated mucosal crypts were measured in control, DSS-only, H. muridarum-infected, and H. muridarum-infected + DSS mice. Results: Prior to DSS challenge, H. muridarum-infected mice showed little distal gut injury by several indices of colon inflammation with decreased blood vessel density in the submucosa, and lower lymphatic density in the mucosa and submucosa. However, after DSS colitis, H. muridarum-infected mice exhibited significantly greater disease. Weight change, stool bleeding, diarrhea, and angiogenesis were all increased in H. muridarum-infected mice in DSS colitis compared to DSS controls. Conclusions: Our data show that Helicobacter colonization of the intestine, unlike that of the stomach, lowers basal gut inflammatory scores, but increases disease activity and inflammation in an acute colitis model. Intestinal Helicobacter infection may therefore represent a significant sub-clinical factor which predisposes the gut to inflammatory injury.

关键词： Helicobacter Colon Lymphatics Crohn’s Disease Ulcerative Colitis

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