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Choosing ankle tourniquets in foot and ankle surgery: Beyond postoperative pain considerations

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World Journal of Orthopedics 2024年第9期15卷 828-830页

作者： Samir Ghandour vijay kumar Jain Ashim Gupta The Faculty of Medicine and Biomedical Sciences The University of BalamandBeirut 1100Lebanon Department of Orthopaedics Atal Bihari Vajpayee Institute of Medical SciencesDr Ram Manohar Lohia HospitalNew DelhiDelhi 110001India Department of Orthopaedics and Regenerative Medicine Future BiologicsLawrencevilleGA 30043United States

This editorial critically explores the use of ankle vs thigh tourniquets in foot and ankle surgery based on a recent study that found no significant difference in postoperative pain between the two placement *** these findings,we argue for the preferential use of ankle tourniquets,highlighting their potential benefits in reducing venous blood stasis and minimizing soft tissue *** approach underscores the importance of considering long-term patient outcomes and vascular health beyond immediate postoperative *** integrating study findings with broader clinical considerations,we hereby advocate for a nuanced approach to tourniquet use that prioritizes patient safety and long-term recovery in conjunction with immediate postoperative pain.

关键词： Lower extremity Deep venous thrombosis Recovery Postoperative outco-mes Intraoperative decision-making

Mycogenic Silver Nanoparticles From Endophytic Trichoderma atroviride with Antimicrobial Activity

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Journal of Renewable Materials 2020年第2期8卷 171-185页

作者： Ahmed Abdel-Azeem Amr A.Nada Anthonia O’Donovan vijay kumar Thakur Amr Elkelish Microbiology Section Department of BotanyFaculty of ScienceUniversity of Suez CanalIsmailia41522Egypt Department of Analysis and Evaluation Egyptian Petroleum Research InstituteNasr CityCairoP.B.11727Egypt Institut Européen des Membranes IEMUMR-5635Univ MontpellierENSCMCNRSMontpellierFrance School of Science and Computing Galway-Mayo Institute of TechnologyGalwayIreland Enhanced Composites and Structures Center School of AerospaceTransport and ManufacturingCranfield UniversityBedfordshireUK Botany Section Department of BotanyFaculty of ScienceUniversity of Suez CanalIsmailia41522Egypt

There is an increasing interest in developing nanoparticles with diverse biologic *** this end,we prepared 10 to 15 nm silver nanoparticles(AgNP)from native isolates of Trichoderma *** this study,endophytic fungi hosted four medicinal plants in Saint Katherine Protectorate,South Sinai,Egypt have been isolated by surface sterilization technique on four isolation *** species,based on their frequency of occurrence,out of twenty recovered taxa were tested for their capability to synthesize extracellular *** atroviride hosted Chiliadenus montanus was found to be the best candidate for the production of mycogenic AgNPs among all examined *** mycosynthesized AgNPs were compared with chemically synthesized and characterized using Ultraviolet-visible(UV-vis)spectroscopy,Raman spectroscopy,X-ray diffraction(XRD)and high-resolution transmission electron microscopy(HRTEM)*** HRTEM result showed the distribution of spherical AgNPs ranging from 10 to 15 *** atroviride isolate was subjected to sequencing for confirmation of phenotypic *** internal transcribed spacer(ITS)1-5.8 s-ITS2 rDNA sequences obtained were compared with those deposited in the GenBank Database and registered with accession number MH283876 in the NCBI ***,anticandidal and antifungal effects of chemically and mycosynthesized AgNPs were examined at various concentrations in vitro against six pathogenic bacteria and 4 pathogenic fungi by agar well diffusion *** antibiotics;Gentamicin,Amoxicillin,Clotrimazole,and Nystatin at 5μg/disk were taken as positive controls,while 5%DMSO was used as the negative *** data revealed that the application of mycogenic AgNPs at a concentration of 100 ppm resulted in maximum inhibition of pathogenic bacteria and *** data suggest that AgNPs from native isolates of Trichoderma atroviride(MH283876)offer a source of rapid synthesis of eco-friendly,e

关键词： Antimicrobial endobionts mycogenic AgNPS Saint Katherine Protectorate

Canada’s role in strengthening global health security during the COVID-19 pandemic

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Global Health Research and Policy 2020年第1期5卷 290-292页

作者： vijay kumar Chattu Anil Adisesh Sanni Yaya Division of Occupational Medicine Department of MedicineUniversity of TorontoTorontoONCanada Occupational Medicine Clinic St.Michael’s HospitalUnity Health TorontoTorontoONCanada Institute of International Relations The University of the West IndiesSt.AugustineTrinidad and Tobago School of International Development and Global Studies Faculty of Social SciencesUniversity of OttawaOttawaONCanada The George Institute for Global Health University of OxfordOxfordUK

The world is confronted by the current pandemic of Corona Virus Disease(COVID-19),which is a wake-up call for all nations irrespective of their development status or geographical *** the start of the century we have seen five big infectious outbreaks which proved that epidemics are no more regarded as historic and geographically confined *** Canadian government underlined that these infectious disease outbreaks are threats to global health security and disrupt societal wellbeing and *** this context,the Public Health Agency of Canada is proactive and has shown its preparedness for outbreaks of emerging and epidemic-prone diseases,and in dealing with these *** before the declaration of pandemic,Canada has proved its global health leadership by ensuring collective action and multisectoral coordination which still remains a serious challenge especially for low and middle-income countries with existing poor health *** this article we discuss how Canada is addressing the global challenges posed by the COVID-19 pandemic through its leadership and practice of global health diplomacy.

关键词： Coronavirus outbreak COVID-19 Pandemic Epidemic Global health security Canada Public health Epidemic curve Public health emergency of international concern

Antimalarial drug artesunate affords protection against carrageenan induced acute inflammation in rat

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BIOCELL 2014年第1期38卷 1-5页

作者： vijay L.kumar B.GURUPRASAD Priyanka CHAUDHARY Department of Pharmacology All India Institute of Medical SciencesAnsari NagarNew Delhi-110029India Department of Plant Molecular Biology Delhi University South CampusBenito Juarez RoadDhaula KuanNew Delhi-110021India.

Artesunate, an antimalarial drug, has been shown to inhibit the release of inflammatory mediators in various disease conditions. The present study was carried out to evaluate the anti-edematogenic effect of arte- sunate in the rat paw edema model. Inflammation was induced in the hind paw of rat by sub-plantar injection of 0.1 mL of 0.5% carrageenan and the paw volume was measured up to a fixed mark just before the injection and then after 3 h. The difference in two volumes gave a measure of edema formation. At 3h the level of TNF-α, PGE_(2) and myeloperoxidase were estimated in the inflamed paw tissue. Treatment of rats with single dose of artesunate at 50 and 150 mg/kg produced a dose-dependent inhibition in paw inflammation where a significant reduction in edema volume and mediator release was observed. Our study shows that by inhibiting the release of inflam- matory mediators artesunate affords protection against acute inflammation induced in the rat paw and suggests that it has a potential to be used in the treatment of inflammatory disease conditions.

关键词： Artesunate edema myeloperoxidase TNF-α PGE_(2)

Synthesis, Characterization and Remedial Action of Biogenic Silver Nanoparticles and Chitosan-Silver Nanoparticles against Bacterial Pathogens

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Journal of Renewable Materials 2022年第12期10卷 3093-3105页

作者： Piyush kumar Gupta D.Karthik kumar M.Thaveena Soumya Pandit Somya Sinha R.Ranjithkumar Walaa F.Alsanie vijay kumar Thakur Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater Noida201310Uttar PradeshIndia Viyen Biotech LLP CoimbatoreTamil Nadu641031India Department of Biotechnology Kongunadu Arts and Science CollegeCoimbatoreTamil Nadu641029India Department of Biotechnology Graphic Era Deemed to be UniversityDehradunUttarakhand248002India Department of Clinical Laboratories Sciences The Faculty of Applied Medical SciencesTaif UniversityTaif21944Saudi Arabia Biorefining and Advanced Materials Research Center SRUCEdinburghEH93JGUK Department of Mechanical Engineering School of EngineeringShiv Nadar UniversityNoidaGreater Noida201314India School of Engineering University of Petroleum&Energy Studies(UPES)DehradunUttarakhand248007India

Custard apple is a dry land *** leaves exhibit different pharmacological *** the present study,both silver(Ag)nanoparticles and chitosan-coated Ag(Chi-Ag)nanoparticles were fabricated using the aqueous leaf extract of the custard apple *** preliminary phytochemical analysis,various types of phytocompounds were found in the aqueous leaf extract of the same ***,both nanoparticles were physiochemically *** analysis exhibited the fingerprint vibrational peaks of active bioactive compounds in plant extract,Ag nanoparticles,and Chi-Ag ***/Visible spectral analysis revealed the highest absorbance peak at 419 nm,indicating the presence of Ag *** analysis presented the face-centered cubic(FCC)structure of both prepared ***,the average crystalline size of both Ag nanoparticles and Chi-Ag nanoparticles was calculated to be 23 and 74 nm,*** analysis showed the spherical and cubical shapes of Ag nanoparticles and Chi-Ag nanoparticles,*** analysis indicated a peak around 3.29 keV,conforming to the binding energies of Ag *** biogenic nanomaterial also showed strong antibacterial activity against all tested bacterial pathogens.

关键词： Custard apple chitosan Ag nanoparticles Chi-Ag nanoparticles antibacterial

高速火焰喷涂VC-CuNiCr涂层的耐腐蚀性能

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Journal of Central South University 2024年第5期31卷 1385-1397页

作者： SINGH Vikrant BANSAL Anuj SINGLA Anil kumar kumar vijay Sant Longowal Institute of Engineering and Technology Longowal Sangrur 148106India Industrial and Production Engineering Department Dr B R Ambedkar National Institute of TechnologyJalandhar 144011India

本研究采用高速火焰喷涂(HVOF)沉积技术,将碳化钒(VC)和铜镍铬(CuNiCr)复合涂层应用于SS316不锈钢上,以解决不锈钢在海洋环境中的腐蚀问题。在室温环境下,在3.5%氯化钠溶液中进行电化学腐蚀,通过扫描电子显微镜(SEM)和能量色散光谱(EDS... 详细信息

本研究采用高速火焰喷涂(HVOF)沉积技术,将碳化钒(VC)和铜镍铬(CuNiCr)复合涂层应用于SS316不锈钢上,以解决不锈钢在海洋环境中的腐蚀问题。在室温环境下,在3.5%氯化钠溶液中进行电化学腐蚀,通过扫描电子显微镜(SEM)和能量色散光谱(EDS)对有涂层和未覆涂层样品的表面形貌进行检测。结果表明,涂层内由铜(Cu)、镍(Ni)和铬(Cr)组成的金属间黏合剂在氯化钠介质的影响下发生变质,从而导致出现衬底间的局部点蚀现象。有趣的是,在涂层配方中加入碳化钒(VC)显著地增强了表面的耐腐蚀性能,从而阻止了密闭腐蚀凹坑的出现。在不同类的涂层中,加入VC的效果最好,最小的腐蚀速率为72.38×10^(-3)mm/a,相比之下,SS316基底的腐蚀速率最快。

关键词：高速火焰喷涂碳化钒铜镍铬电化学腐蚀氯化钠溶液

Eat more natural dietary fiber and whole grains to minimize liver disease risk

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 601-604页

作者： Rachel M.Golonka Beng San Yeoh Matam vijay-kumar Department of Physiology and Pharmacology University of Toledo College of Medicine and Life SciencesToledoOHUSA

Nutritional habits in the United States have dramatically changed since the Industrial Revolution in the 18th ***,not every‘advancement’from then to now has improved human dietary habits and *** is evident from the rising epidemic of nutritional insufficiencies associated with the increasing prevalence of age-related diseases(1).Work from Dennis Burkett in the late 1960s was one of the first to hypothesize that refinement of grains and removal of dietary fiber could explain the regional dichotomy in disease incidence(2).

关键词： fiber refinement grains

A review on pharmacological and analytical aspects of diosgenin:a concise report

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Natural Products and Bioprospecting 2012年第2期2卷 46-52页

作者： Kanika PATEL Manoj GADEWAR vijay TAHILYANI Dinesh kumar PATEL G.L.A Institute of Pharmaceutical Research MathuraIndia S.K.I.P.S.Warangal A.P.India Sonekar College of Pharmacy KoradiNagpurIndia Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasi 221005India

Diosgenin is a steroidal sapogenin found in plants such as Dioscorea nipponoca,Solanum incanum,Solanum xanthocarpum and Trigonella foenum ***,biologically active phytochemicals have been used for the treatment of various types of disorder such as leukemia,inflammation,hypercholesterolemia and *** is also able to prevent bone loss to the same extent as that of *** is a typical initial intermediate for synthesis of steroidal compounds,oral contraceptives and sex ***,Costus and Trigonella are mainly used for the production of *** the basis of literature survey it divulges that diosgenin has very impressive pharmacological profile and could be used as a medicine for the treatment of different types of disorders in the ***,the present work aims to provide collective information in concern with its pharmacological activity and phytoanalytical *** review will be beneficial to researches for the development of an alternative method for the treatment of innumerable diseases from diosgenin.

关键词： analytical techniques cancer diosgenin pharmacological activity plant source seperation techniques

Erasure coding for distributed storage: an overview

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Science China(Information Sciences) 2018年第10期61卷 7-51页

作者： S.B.BALAJI M.Nikhil KRISHNAN Myna VAJHA Vinayak RAMkumar Birenjith SASIDHARAN P.vijay kumar Department of Electrical Communication Engineering Indian Institute of Science Ming Hsieh Department of Electrical Engineering University of Southern California

In a distributed storage system, code symbols are dispersed across space in nodes or storage units as opposed to time. In settings such as that of a large data center, an important consideration is the efficient repair of a failed node. Efficient repair calls for erasure codes that in the face of node failure,are efficient in terms of minimizing the amount of repair data transferred over the network, the amount of data accessed at a helper node as well as the number of helper nodes contacted. Coding theory has evolved to handle these challenges by introducing two new classes of erasure codes, namely regenerating codes and locally recoverable codes as well as by coming up with novel ways to repair the ubiquitous Reed-Solomon code. This survey provides an overview of the efforts in this direction that have taken place over the past decade.

关键词： distributed storage regenerating codes locally recoverable codes codes with locality erasure codes node repair