检索结果-南通市图书馆

The emerging ro.e o. mesenchymal stem cell-derived extracellular vesicles to.amelio.ate hippo.ampal NLRP3 inflammatio. induced by binge-like ethano. treatment in ado.escence

引用

Neural Regeneratio. Research 2025年第4期20卷 1153-1163页

作者： Susana Mellado.María Jo.éMo.illo.Bargues Carla Perpiñá-Clérigues Francisco.García-García victoria Mo.eno.Manzano.Co.suelo.Guerri María Pascual Department o. Physio.o.y School of Medicine and DentistryUniversity of ValenciaValenciaSpain Bio.nfo.matics and Bio.tatistics Unit Príncipe Felipe Research CenterValenciaSpain Neuro.al and Tissue Regeneratio. Labo.ato.y Príncipe Felipe Research CenterValenciaSpain

o.r previo.s studies have repo.ted that activatio. o. the NLRP3(No.-,LRR-and pyrin do.ain-co.taining pro.ein 3)-inflammaso.e co.plex in ethano.-treated astro.ytes and chro.ic alco.o.-fed mice co.ld be asso.iated with neuro.nflammatio. and brain *** stem cell-derived extracellular vesicles(MSC-EVs)have been sho.n to.resto.e the neuro.nflammato.y respo.se,alo.g with myelin and synaptic structural alteratio.s in the prefro.tal co.tex,and alleviate co.nitive and memo.y dysfunctio.s induced by binge-like ethano. treatment in ado.escent *** the therapeutic ro.e o. the mo.ecules co.tained in mesenchymal stem cell-derived extracellular vesicles,the present study analyzed whether the administratio. o. mesenchymal stem cell-derived extracellular vesicles iso.ated fro. adipo.e tissue,which inhibited the activatio. o. the NLRP3 inflammaso.e,was capable o. reducing hippo.ampal neuro.nflammatio. in ado.escent mice treated with binge *** demo.strated that the administratio. o. mesenchymal stem cell-derived extracellular vesicles amelio.ated the activatio. o. the hippo.ampal NLRP3 inflammaso.e co.plex and o.her NLRs inflammaso.es(e.g.,pyrin do.ain-co.taining 1,caspase recruitment do.ain-co.taining 4,and absent in melano.a 2,as well as the alteratio.s in inflammato.y genes(interleukin-1β,interleukin-18,inducible nitric o.ide synthase,nuclear facto.-kappa B,mo.o.yte chemo.ttractant pro.ein-1,and C–X3–C mo.if chemo.ine ligand 1)and miRNAs(miR-21a-5p,miR-146a-5p,and miR-141-5p)induced by binge-like ethano. treatment in ado.escent *** analysis further revealed the invo.vement o. miR-21a-5p and miR-146a-5p with inflammato.y target genes and No.-like recepto. signaling *** to.ether,these findings pro.ide no.el evidence o. the therapeutic po.ential o. MSC-derived EVs to.amelio.ate the hippo.ampal neuro.nflammato.y respo.se asso.iated with NLRP3 inflammaso.e activatio. induced by binge drinking in ado.escence.

关键词： ado.escence binge-like ethano. treatment extracellular vesicles hippo.ampus mesenchymal stem cells neuro.nflammatio. No.-,LRR-and pyrin do.ain-co.taining pro.ein 3(NLRP3)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Targeting harmful effects o. no.-excitato.y amino.acids as an alternative therapeutic strategy to.reduce ischemic damage

引用

Neural Regeneratio. Research 2025年第9期20卷 2454-2463页

作者： victoria Jiménez Carretero.IrisÁlvarez-Merz Jo.ge Hernández-Campano.Sergei A.Kiro. Jesús M.Hernández-Guijo Department o. Pharmaco.o.y and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón y Cajal Institute fo. Health Research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute o. Neuro.io.o.y Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Department o. Neuro.cience and Regenerative Medicine&Department o. Neuro.urgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The invo.vement o. the excitato.y amino.acids glutamate and aspartate in ce rebral ischemia and excito.o.icity is ***,the ro.e o. no.-excitato.y amino.acids in brain damage fo.lo.ing a stro.e o. brain trauma remains largely *** release o. amino.acids by necro.ic cells in the ischemic co.e may co.tribute to.the expansio. o. the *** findings indicated that the reversible lo.s o. field excitato.ry po.tsynaptic po.entials caused by transient hypo.ia became irreversible when expo.ed to.a mixture o. just fo.r no.-excitato.y amino.acids(L-alanine,glycine,L-glutamine,and L-serine)at their plasma *** amino.acids induce swelling in the so.as o. neuro.s and astro.ytes during hypo.ia,alo.g with permanent dendritic damage mediated by N-methyl-D-aspartate *** N-methyl-D-aspartate recepto.s prevented neuro.al damage in the presence o. these amino.acids during *** is likely that astro.lial swelling caused by the accumulatio. o. these amino.acids via the alanine-serine-cysteine transpo.ter 2 exchanger and system N transpo.ters activates vo.ume-regulated anio. channels,leading to.the release o. excito.o.ins and subsequent neuro.al damage thro.gh N-methyl-D-aspartate recepto. ***,previo.sly unreco.nized mechanisms invo.ving no.-excitato.y amino.acids may co.tribute to.the pro.ressio. and expansio. o. brain injury in neuro.o.ical emergencies such as stro.e and traumatic brain *** these pathways co.uld highlight new therapeutic targets to.mitigate brain injury.

关键词： cell swelling N-methyl-D-aspartate recepto. no.-excitato.y amino.acids stro.e synaptic transmissio.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pro.o. pump inhibito.s and all-cause mo.tality risk amo.g cancer patients

引用

Wo.ld Jo.rnal o. Clinical o.co.o.y 2025年第1期16卷 34-42页

作者： Arunkumar Krishnan Caro.in victoria Schneider Declan Walsh Department o. Suppo.tive o.co.o.y Atrium Health Levine CancerCharlotteNC 28204United States Department o. Medicine Section of Hematology and OncologyWake Forest University School of MedicineWinston-SalemNC 27101United States Department o. Medicine Ⅲ GastroenterologyMetabolic Diseasesand Intensive CareUniversity Hospital RWTH AachenAachen 52074Germany

BACKGRo.ND Pro.o. pump inhibito.s(PPIs)are widely used,including amo.g cancer patients,to.manage gastro.so.hageal reflux and o.her gastric acid-related *** evidence suggests asso.iatio.s between lo.g-term PPI use and higher risks fo. vario.s adverse health o.tco.es,including greater *** To.investigate the asso.iatio. between PPI use and all-cause mo.tality amo.g cancer patients by a co.prehensive analysis after adjustment fo. vario.s co.fo.nders and a ro.ust metho.o.o.ical appro.ch to.minimize *** This retro.pective co.o.t study used data fro. the TriNetX research netwo.k,with electro.ic health reco.ds fro. multiple healthcare *** study emplo.ed a new-user,active co.parato. design,which co.pared newly treated PPI users with no.-users and newly treated histamine2 recepto. antago.ists(H2RA)users amo.g adult cancer *** prescribed PPIs(eso.eprazo.e,lanso.razo.e,o.eprazo.e,panto.razo.e,o. rabeprazo.e)users were co.pared to.no.-users o. newly prescribed H2RAs(cimetidine,famo.idine,nizatidine,o. ranitidine)*** primary o.tco.e was all-cause *** patient in the main gro.p was matched to.a patient in the co.tro. gro.p using 1:1 pro.ensity sco.e matching to.reduce co.fo.nding *** Co. regressio. mo.els were used to.estimate hazard ratio.(HRs)and 95% co.fidence interval(CI).RESULTS During the fo.lo.-up perio.(median 5.4±1.8 years fo. PPI users and 6.5±1.0 years fo. no.-users),PPI users demo.strated a higher all-cause mo.tality rate than no.-users after 1 year,2 years,and at the end o. fo.lo. up(HRs:2.34-2.72).Co.pared with H2RA users,PPI users demo.strated a higher rate o. all-cause mo.tality HR:1.51(95%CI:1.41-1.69).Similar results were o.served acro.s sensitivity analyses by excluding deaths fro. the first 9 mo.ths and 1-year po.t-expo.ure,co.firming the ro.ustness o. these *** a sensitivity analysis,we analyzed all-cause mo.tality o.tco.es between fo.mer PPI users and individual

关键词： All-cause mo.tality Cancer Histamine-2 recepto. antago.ists Mo.tality Malignancy Pro.o. pump inhibito.s Carcino.a o.tco.e

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Facilities and Misco.ceptio.s Co.cerning Menstrual Health and Menstrual Hygiene Management amo.g Yo.ng Peo.le in Jo., Plateau State, Nigeria

引用

o.en Jo.rnal o. o.stetrics and Gyneco.o.y 2023年第5期13卷 918-933页

作者： Lucy o. Ido.o.Kingsley C. o.afo. ayegb. o. victoria Department o. Co.munity Medicine & PHC Bingham University Karu Nasarawa State Nigeria

Backgro.nd: Glo.ally, wo.en co.stitute 49.6% o. the wo.ld po.ulatio. and at least 500 millio. wo.en and girls lack adequate facilities fo. menstrual hygiene management. In Nigeria, a quarter o. wo.en lack adequate privacy fo. defecatio. and menstrual hygiene management. Absence o. facilities needed fo. menstrual hygiene can po.e as o.stacle to.wo.en and girls practicing menstrual hygiene effectively. This study aims to.identify the facilities and misco.ceptio.s co.cerning menstrual health and menstrual hygiene management. Metho.s: This was a descriptive cro.s-sectio.al study amo.g 169 yo.ng males and females o. Evangelical Church Winning All (ECWA) Theo.o.ical Seminary, Jo. No.th, Plateau State. This study so.ght to.identify the facilities and misco.ceptio.s co.cerning menstrual health and menstrual hygiene management amo.g yo.ng peo.le in Jo., Plateau State. Nigeria. Simple rando. sampling technique was used in this study and data was co.lected using interviewer-administered structured questio.naire to.measure availability o. facilities/pro.rams fo. menstrual hygiene management and misco.ceptio.s abo.t menstruatio.. Data analysis was do.e using the Statistical Package fo. the So.ial Science (SPSS) versio. 20.0 with descriptive statistics, pro.o.tio.s, tables and diagrams used to.illustrate findings fro. the data co.lected. Results: Majo.ity 139 (82.2%) o. the female respo.dents had access to.adequate water supply, while 30 (17.8%) did no. have access to.the adequate water supply. Abo.t half, 53.8% had bathro.ms with do.rs and safe lo.ks, 19.5% had a scho.l clinic where menstrual abso.bents can be go.ten, 10 (5.9%) had Girl’s Club/Peer Educatio. teams, 24 (14.2%) had guidance and co.nselling classes. Pro.rammes available to.female respo.dents fo. menstrual health and hygiene management were girls club and guidance and co.nselling sessio.s. Majo.ity 94 (97.9) o. females have access to.so.e fo.m o. menstrual adso.bent material, and 50 (52.1%) had no.access to.Sanitary

关键词： Menstrual Hygiene Menstrual Health Misco.ceptio.s Myths

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Immuno.nfo.matics assisted design o. a multi-epito.e kit fo. detecting Cro.o.acter sakazakii in po.dered infant fo.mula

引用

Fo.D QUALITY AND SAFETY 2024年第8期8卷 322-333页

作者： o.adipo. Elijah K. o.isanya, o.ukayo.e, I o.o.ye, victoria o. Shittu, o.inlo.a G. Adamito.de, Mautin G. Ikwuka, Emmanuel C. o.ewale, So.o.o. o. Tijani, Adewale J. Adedo.un, Feranmi A. Adedo.un, Amudatu A. o.edepo. Temito.e A. o.yeaka, Helen Adeleke Univ Dept Microbiol Lab Mol Biol Immunol & Bioinformat Ede Osun State Nigeria Helix Bio.en Inst Genom Unit Ogbomosho Oyo State Nigeria Lado.e Akinto.a Univ Techno. Dept Microbiol Ogbomosho Oyo State Nigeria Univ Lago. Coll Med Dept Med Lab Sci Lagos Nigeria o.afemi Awo.o.o.Univ Dept Microbiol Ife Osun State Nigeria Lado.e Akinto.a Univ Techno. Dept Physiol Ogbomosho Oyo State Nigeria Lado.e Akinto.a Univ Techno. Dept Human Anat Ogbomosho Oyo State Nigeria Fed Univ Techno. Akure Dept Biotechnol Akure Ondo State Nigeria Lado.e Akinto.a Univ Techno. Dept Biochem Ogbomosho Oyo State Nigeria Fo.ntain Univ Med Lab Sci Dept Osogbo Osun State Nigeria Adeleke Univ Dept Biochem Ede Osun State Nigeria Univ Birmingham Sch Chem Engn Birmingham England Univ Birmingham Sch Chem Engn Birmingham B12 2TT England

o.jectives Cro.o.acter sakazakii, fo.merly Entero.acter sakazakii, is an emerging ubiquito.s and o.po.tunistic fo.dbo.ne patho.en with a high mo.tality rate. It has been implicated in cases o. meningitis, septicaemia, and necro.izing entero.o.itis amo.g infants wo.ldwide in asso.iatio. with po.dered infant fo.mula (PIF). This study was an insilico.designed peptide base kit framewo.k, using immuno.nfo.matic techniques fo. quick detectio. o. C. sakazakii in *** and Metho.s In the present study, a peptide-based kit was designed with a bio.nfo.matic technique to.rapidly identify C. sakazakii in PIF using flhE, secY, and bcsC, which are genes respo.sible fo. its bio.ilm fo.matio., as target genes. The antigenicity, membrane to.o.o.y, and the presence o. signal peptides o. the target genes were analysed using VaxiJen, DeepTMHMM, and SignalP servers. To.pro.ide stability and flexibility to.the multiple-epito.e co.struct, the linear B cells and helper T cells (IL-4 (interleukin 4) and IL-10 (interleukin 10) inducing epito.es) were linked with a GSGSG linker fo.lo.ed by the additio. o. pro.ein disulphide bo.ds. To.ascertain specificity, the multi-epito.e co.struct was mo.ecularly do.ked against genes fro. so.rces o.her than PIF, like alfalfa, and the enviro.ment, with PIF being the highest: -328.48. Finally, the co.o.s were mo.ified using the pET28a(+) vecto., and the resultant multi-epito.e co.struct was successfully clo.ed in *** The final co.struct had a length o. 486 bp, an instability index o. 23.26, a theo.etical pI o. 9.34, a mo.ecular weight o. 16.5 kDa, and a Z-sco.e o. -*** The multi-epito.e peptide co.struct co.ld be a co.ceptual framewo.k fo. creating a C. sakazakii peptide-based detectio. kit, which has the po.ential to.pro.ide fast and efficient detectio.. Ho.ever, there is a need fo. additio.al validatio. thro.gh the in vitro.and in vivo.techniques.

关键词： Po.dered infant fo.mula Cro.o.acter sakazakii bio.nfo.matics immuno.nfo.matics detectio. kit peptide-based epito.es analytical kits reco.binant fusio. pro.ein peptides

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

C-glyco.yl flavo.o.d o.ientin alleviates learning and memo.y impairment by radio.requency electro.agnetic radiatio. in mice via impro.ing antio.idant defence mechanism

引用

Asian Pacific Jo.rnal o. Tro.ical Bio.edicine 2019年第12期9卷 518-523页

作者： Isaac o.Akefe Ibrahim L.Yusuf victoria A.Adego.e Department o. Physio.o.y Biochemistry and PharmacologyFaculty of Veterinary MedicineUniversity of JosNigeria Department o. Veterinary Pharmaco.o.y and To.ico.o.y University of MaiduguriNigeria Department o. Science and Labo.ato.y Techno.o.y Ekiti State UniversityNigeria

o.jective: To.investigate the antio.idant efficacy o. o.al o.ientin o. 900 MHz radio.requencyelectro.agnetic radiatio.-induced o.idative stress in ***: The mice were rando.ly allo.ted into.5 gro.ps co.sisting o. 7 mice each. The deio.ised water and radio.requency electro.agnetic radiatio.s(RF-EMR) gro.ps were administered with deio.ised water while o.ientin was administered to.the RF-EMR + lo. do.e o. o.ientin gro.p(10 mg/kg), RF-EMR + high do.e o. o.ientin gro.p(20 mg/kg) and high do.e o. o.ientin gro.p(20 mg/kg). All the gro.ps except deio.ised water and high do.e gro.ps were expo.ed to.900 MHz radio.requency-electro.agnetic radiatio. fo. 28 co.secutive days(1 h/day). Learning and memo.y was assessed via the step-do.n inhibito.y avo.dance task. Activities o. lipid prexidatio. and antio.idant enzymes were measured using ***: Radio.requency electro.agnetic radiatio. caused impairment in learning and memo.y and reduced activities o. brain antio.idant enzymes, increased lipo.ero.idatio. and co.tico.tero.e co.centratio. as well as histo.atho.o.ical aberratio.s in the hippo.ampal tissues. Co.versely, o.ientin alleviated learning and memo.y deficit, impro.ed the activities o. endo.eno.s antio.idant enzymes and mitigated brain lipo.ero.idatio. and neuro.al degeneratio. in mice expo.ed to.radio.requency electro.agnetic radiatio.. Co.clusio.s: o.ientin alleviates learning and memo.y impairment due to.radio.requency electro.agnetic radiatio. in mice by impro.ing antio.idant defence mechanism and may be co.sidered as a pro.ising therapeutic agent fo. impro.ing the antio.idant system o. peo.le living in radio.requency electro.agnetic radiatio.-pro.e enviro.ment.

关键词： o.ientin Antio.idants Radio.requency electro.agnetic radiatio. Mice o.idative stress

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Mo.elling the nesting-habitat o. threatened vulture species in the caucasus:An eco.ystem appro.ch to.fo.malising enviro.mental facto.s in species distributio. mo.els

引用

Avian Research 2023年第4期14卷 572-585页

作者： Rustam Psheguso. victoria Chadaeva Tembo.o. Institute o. Eco.o.y o. Mo.ntain Territo.ies o. Russian Academy o. Science I.Armand Str.37а360051NalchikRussia

Abio.ic facto.s play an impo.tant ro.e in species lo.alisatio.,but bio.ic and anthro.o.enic predicto.s must also.be co.sidered in distributio. mo.elling fo. mo.els to.be bio.o.ically *** this study,we fo.malised the bio.ic predicto.s o. nesting sites fo. fo.r threatened Caucasian vultures by including species distributio. mo.els(wild ungulates,nesting tree species)as bio.ic layers in the vulture Maxent *** was applied in the R dismo.package and the best set o. the mo.el parameters were defined in the R ENMeval *** metrics were co.tinuo.s Bo.ce index,Akaike's info.matio. criterio.,the area under receiver o.erating curve and true skill *** also.calculated and evaluated the null *** density estimatio. metho. was applied to.assess the o.erlap o. vulture eco.o.ical niches in the enviro.mental *** accessibility o. anthro.o.enic fo.d reso.rces was estimated using the Path Distance measure that co.siders elevatio. *** availability o. pine fo.ests(Sco.s Pine)and wild ungulates(Alpine Chamo.s and Caucasian Go.t)co.tributed the mo.t(29.6%and 34.3%)to.Cinereo.s Vulture(Aegypius mo.achus)nesting site *** ungulate distributio. also.co.tributed significantly(abo.t 46%)to.the Bearded Vulture(Gypaetus barbatus)*** scavenger nests in the highlands o. the Caucasus at a minimum distance o. 5–10 km fro. anthro.o.enic *** co.trast,livesto.k as a fo.d so.rce was mo.t impo.tant in co.o.y distributio. o. Griffo. Vulture(Gyps fulvus).The co.tributio. o. distances to.settlements and agricultural facilities to.the mo.el was 45%.The o.timal distance fro. Egyptian Vulture(Neo.hro. percno.terus)nesting sites to.settlements was o.ly 3–10 km,to.livesto.k facilities no.mo.e than 15 km with the facto. co.tributio. o. abo.t 57%.Excluding the wild ungulate availability,the eco.o.ical niches o. studied vultures o.erlapped *** similar fo.aging and nesting requirements,Caucasian vultures are no

关键词： Caucasian vultures Eco.o.ical niche differentiatio. Maxent Nesting sites Species distributio. mo.els

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sho.&Go.TSP heuristics fo. an o.timal sho.ping with smartpho.es

引用

Science China(Info.matio. Sciences) 2013年第11期56卷 45-56页

作者： Inmaculada PARDINES victoria Lo.EZ Department o. Co.puter Architecture Faculty of Computer Science Universidad ComplutenseMadrid 28040 Spain

Mo.ile techno.o.y has been under co.stant gro.th in last *** emergence o. smartpho.es has enco.raged the develo.ment o. a wide variety o. mo.ile *** o. them are related to.daily *** this regard,we pro.o.e the Sho.&Go.mo.ile applicatio. which allo.s a supermarket custo.er to.do.the sho.ping co.ering the sho.test distance1).An analysis o. the ro.ting pro.lem applied to.an efcient way o. do.ng the sho.ping is made.A map with items distributio. and distances between pro.ucts is pro.ided by the *** o. these info.matio. two.heuristics have been pro.o.ed to.do.the sho.ping fo.lo.ing the o.timum *** heuristics have been co.pared,pro.ing that neither o. them can be defned as the best o.e in all *** pro.ucts in the sho.ping list determine which is the best so.utio. fo. each ***,bo.h algo.ithms have been included in o.r applicatio.,letting the user decide which ro.te he/she wants to.***&Go.has also.o.her functio.alities which are extensively described in the *** o.er an HTC Desire mo.ile are sho.n to.demo.strate the pro.er to.l ***,a study o. co.sumer acceptance has been made to.kno. its po.sibilities o. success in the mo.ile techno.o.y market.

关键词： mo.ile applicatio.s ro.ting pro.lems Andro.d o.erating system sho.ping list o.timum path

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Fruit Fly as a Mo.el o.ganism fo. Blo.d-Brain Barrier Penetratio. and Infectio.s Disease in the Nano.edical Niche

引用

Jo.rnal o. Bio.ic Engineering 2020年第3期17卷 553-569页

作者： victoria Meng-Ting Wu Vuk Usko.o.ic MP Bio.edicals 9 GoddardIrvineCA 92618USA Department o. Mechanical and Aero.pace Engineering University of CaliforniaEngineering Gateway 4200Irviney CA 92697USA

Dro.o.hila melano.aster,*** co.mo. fhiit fly,is a simple o.ganism that may give a rapid,high-thro.ghput respo.se in regard to.the therapeutic efficacy o. nano.articles and drugs,while circumventing the high enviro.mental and mo.etary co.t o. to.ay's typical in vivo.assays invo.ving mo.e co.plex animals,alo.g with the immeasurable suffering impo.ed o.to.*** we give the pro.ress repo.t o. o.r effo.t to.turn *** into.a mo.el o.ganism fo. the in vivo.testing o. Blo.d-Brain Barrier(BBB)penetratio. o. nano.particles and the treatment o. infectio.s *** sho. that o.ally ingested superparamagnetic nano.articles successfully cro.s the BBB in *** and lo.alize to.the o.tic lo.es o. the third instar larval brain,while causing no.adverse effects to.the invertebrate *** also.sho. that bo.h o.ally ingested calcium pho.phate nano.articles and bio.ilm-fo.ming *** lo.alize to.the Dro.o.hila cro.,the fo.d sto.age o.gan o. the fly,which shrinks in respo.se to.*** mo.el do.s no. induce mo.tality co.sequential to.infectio. and the effects o. the internalizatio. and pro.iferatio. o. the micro.es are evaluable by measuring the cro. parameters,including fluo.escence intensity and *** develo.ment o. these two.mo.els co.ld simplify the preclinical testing o. medical treatments and o. pharmaceutical agents fo. neuro.o.ical and infectio.s disease,while ensuring ro.ust and reliable levels o. statistical significance at lo. co.t.

关键词： animal mo.el calcium pho.phate in vivo iro. o.ide nano.article

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Kno.ledge and Practice o. Menstrual Health and Hygiene amo.g Yo.ng Peo.le in Jo., Plateau State, Nigeria

引用

o.en Jo.rnal o. o.stetrics and Gyneco.o.y 2022年第4期12卷 292-308页

作者： Lucy o. Ido.o.Kingsley C. o.afo. victoria o. ayegb. Sarah Bala Victo. B. Evuka Department o. Co.munity Medicine & PHC Bingham University Karu Nasarawa State Nigeria

Backgro.nd: The perio.ic shedding o. the lining o. a wo.an’s uterus is referred to.as Menstruatio., o. a menstrual perio.. o.er a perio. o. three to.five days, the uterine lining breaks do.n into.a blo.dy substance. It then passes do.n thro.gh the cervix and exits thro.gh the vagina. Menstrual health kno.ledge is regarded as having kno.ledge o. what menstruatio. is and the need fo. effective management o. health during menstruatio. and pro.er menstrual hygiene management. This study seeks to.assess the kno.ledge and practice o. menstrual health and hygiene and availability o. reso.rces fo. effective menstrual hygiene management amo.g yo.ng peo.le in Jo., Plateau State, Nigeria. Metho.o.o.y: This was a descriptive cro.s-sectio.al study carried o.t amo.g 169 yo.ng males and females o. Evangelical Church Winning All (ECWA) Theo.o.ical Seminary, Jo., No.th, Plateau State, Nigeria. Simple rando. sampling technique was used in this study and data was co.lected using an interviewer-administered structured questio.naire. Data analysis was do.e using the Statistical Package fo. the So.ial Science (SPSS) versio. 20.0. Findings: Majo.ity o. 70 (41.4%) respo.dents fall within the age range o. 20 - 24 years o.d, 64 (37.9%) were within 25 - 29 years. There were mo.e females (96, 56.8%) than males (73, 43.2%). Twenty (11.8%) were married, 149 (88.2%) were single. Mo.e than three quarters (78.1%) had go.d kno.ledge o. Menstrual Hygiene. o. this, 64.4% are males and 88.5% are females. 18.3% o. respo.dents had fair kno.ledge. o. this, 30.1% are males and 9 (9.4%) are females. 6 (3.6%) o. respo.dent’s had po.r kno.ledge o. menstrual hygiene (4 (5.5%) o. males and 2 (92.1%)) o. females). Two.thirds o. the female respo.dents had go.d practice o. menstrual hygiene, while a third o. the respo.dents had the po.r practice o. menstrual hygiene. Co.clusio.: There was go.d kno.ledge and practice o. menstruatio. and menstrual hygiene amo.g yo.ng peo.le. Kno.ledge influences practice and the per

关键词： Menstrual Health Menstrual Hygiene Kno.ledge Practice

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：