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Updating the distribution of Nothofagus alessandrii: Impact of deforestation, fragmentation and connectivity

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FOREST ECOSYSTEMS 2025年第01期12卷 136-145页

作者： Cabrera-Ariza, Antonio M. Rivas, Carlos A. Aguilera-Peralta, Miguel navarro-Cerrillo, Rafael M. Santelices-Moya, Romulo Univ Catolica Maule Ctr Invest Estudios Avanzados Maule Ave San Miguel 3605 Talca 3460000 Chile Univ Catol Maule Fac Ciencias Agr & Forestales Ctr Desarrollo Secano Interior Talca 3460000 Chile Univ Cordoba Lab Dendrochronol Silviculture & Global Change DendrodatLab ERSAF Dept Forest Engn Cordoba Spain

Nothofagus alessandrii forests in the Mediterranean region of Chile face significant threats from deforestation, fragmentation, wildfires, and climate change. This study investigated the temporal and spatial dynamics of N. alessandrii populations and their implications for habitat fragmentation and connectivity. Using remote sensing data and geographic information system analysis, we assessed deforestation patterns, fragmentation metrics, and connectivity indices for different scenarios between 2009 and 2022. A reduction in the N. alessandrii forest area, extensive fragmentation, and decreased connectivity were observed over time, with wildfires exacerbating these trends. Reforestation simulations showed the potential of targeted restoration efforts to improve connectivity, especially when focusing on proximate patches. However, careful consideration of seed dispersal distances and wildfire risk is essential for effective reforestation planning. Overall, our findings underscore the urgent need for conservation interventions to preserve N. alessandrii forests and their biodiversity in Chile's coastal mountain ecosystems. A proactive and collaborative approach is essential to ensure the survival of these forests for future generations.

关键词： Ruil Endangered species Red list IUCN Conservation biology

Controversies around the treatment of peritoneal metastases of colorectal cancer

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World journal of Gastrointestinal Oncology 2025年第1期17卷 260-264页

作者： Francisco j Morera-Ocon Clara navarro-Campoy Ticiano Guastella Francisco Landete-Molina Department of General Surgery Hospital General de RequenaRequena 46340Spain Department of Gynecology and Obstetrics Hospital 9 OctubreValencia 46015Spain Department of Pathology Hospital General de RequenaRequena 46340Spain

In this editorial we examine the article by Wu et al published in the World journal of Gastrointestinal *** resection for peritoneal metastases from colorectal cancer(CRC)has been gradually accepted in the medical oncology community.A randomized trial(PRODIGE 7)on cytoreductive surgery(CRS)with hyperthermic intraperitoneal chemotherapy(HIPEC)failed to prove any benefit of oxaliplatin in the overall survival of patients with peritoneal metastases from colorectal ***,isolated systemic chemotherapy for CRC stage IV has demonstrated a reduced response in peritoneal metastases than that obtained in other metastatic sites such as the *** tool is required in those patients to achieve more local control of the *** groups in peritoneal surgery continue to use HIPEC in their procedures,using other agents than oxaliplatin for peritoneal cavity infusion,such as mitomycin *** patients present with complex surgical issues to manage,and consequently a large burden of complications has to be ***,identifying patients who will benefit from CRS with or without HIPEC would be of great interest.

关键词： Colorectal cancer Peritoneal metastasis Hyperthermic intraoperative chemotherapy Treatment strategies Peritoneal Surface Oncology GroupInternational

Simultaneous pars plana vitrectomy,panretinal photocoagulation,cryotherapy,and Ahmed valve implantation for neovascular glaucoma

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International journal of Ophthalmology(English edition) 2021年第9期14卷 1396-1401页

作者： Carolina Bernal-Morales Marina Dotti-Boada Alvaro Olate-Perez Manuel j.navarro-Angulo Laura Pelegrín Marc Figueras-Roca Institut Clínic d’Oftalmologia(ICOF) Hospital ClínicBarcelona 08028Spain August Pi i Sunyer Biomedical Research Institute(IDIBAPS) Barcelona 08028Spain

AIM:To describe and evaluate the efficacy of Ahmed glaucoma valve implantation(AGV)combined with pars plana vitrectomy(PPV)in a single surgical act for the treatment of advanced neovascular glaucoma(NVG).METHODS:Retrospective observational case series included 51 eyes from 50 patients with severe NVG treated with PPV,AGV,and panretinal photocoagulation and/or cryotherapy in a single surgical act during a 13-year period(2005-2018).Preoperative,intraoperative and postoperative data at day 1 and months 1,3,6,21,and 24 were systematically *** of surgical success was stablished at IOP between 6 and 21 mm Hg with or without topical ***:Main indications for surgery were NVG secondary to proliferative diabetic retinopathy(39.2%)and central retinal vein occlusion(37.3%).Mean(±SD)preoperative IOP was 42.0±11.2 mm Hg decreasing to 15.5±7.1 mm Hg at 12 mo and 15.8±9.1 mm Hg at 24 mo of follow *** incidence of success of IOP control was 76.0%at first postoperative month,reaching 88.3%at 6 *** of successful IOP control at long term was 74.4%at 12 mo and 71.4%at 24 *** evisceration for unsuccessful NVG management was required in 1 case(2.0%).CONCLUSION:Combination of AGV implantation and PPV in a single act may be a suitable option for severe forms of NVG in a case-by-case basis for effective IOP control and a complete panretinal photocoagulation.

关键词： neovascular glaucoma Ahmed valve pars plana vitrectomy panretinal photocoagulation cryotherapy

Climate Change and Congenital Heart Disease:A Narrative Review

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Congenital Heart Disease 2024年第6期19卷 627-634页

作者： Ethan Katznelson Matthew j.navarro Su Yuan Dhurv S.Kazi Harsimran S.Singh Weill Cornell Medicine Greenberg Division of CardiologyNew York Presbyterian Hospital-Weill Cornell MedicineNew York10065USA Department of Medicine New York Presbyterian Hospital-Weill Cornell MedicineNew York10065USA Richard A.and Susan F.Smith Center for Outcomes Research in Cardiology Beth Israel Deaconess Medical CenterBoston02215USA

Congenital Heart Disease(CHD)is the most common birth defect and a leading cause of infant morbidity and mortality *** genetic factors play a significant role in its development,up to 30%of CHD is associated with modifiable risk factors and external maternal *** change,driven by increased atmospheric pollutants fromfossil fuel combustion,leads to rising global temperatures andworsening air quality,which pose emerging threats to maternal and fetal *** review explores the mechanisms by which environmental factors associated with climate change,specifically extreme heat and air pollution,may influence CHD *** exposure to extreme heat during the first trimester is linked to an increased risk of atrial and ventricular septal defects in offspring,with risk correlating to the intensity and duration of heat *** pollution—particularly fine particulate matter and gases like ozone,nitrogen dioxide,and sulfur dioxide—is associated with a broader spectrum of CHD,including tetralogy of Fallot,pulmonary stenosis,and coarctation of the *** effects are present even when the exposure occurred prior to *** effects between air pollution and other exposures,such as tobacco use,may further amplify CHD *** should be aware of the potential risks associated with environmental exposures and counsel prospective mothers accordingly to mitigate CHD risk in their offspring.

关键词： Climate change congenital heart disease extreme heat air pollution

Reconstruction of pile-up events using a one-dimensional convolutional autoencoder for the NEDA detector array

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Nuclear Science and Techniques 2025年第2期36卷 62-70页

作者： j.M.Deltoro G.jaworski A.Goasduff V.González A.Gadea M.Palacz j.j.Valiente-Dobón j.Nyberg S.Casans A.E.navarro-Antón E.Sanchis G.de Angelis A.Boujrad S.Coudert T.Dupasquier S.Ertürk O.Stezowski R.Wadsworth Department of Electronic Engineering University of ValenciaBurjassotValenciaSpain Heavy Ion Laboratory University of Warsaw02-093 WarsawPoland Istituto Nazionale di Fisica Nucleare Laboratori Nazionali di LegnaroLegnaroItaly Instituto de Física Corpuscular CSIC-Universidad de Valencia46980 PaternaValenciaSpain Department of Physics and Astronomy Uppsala UniversityUppsalaSweden GANIL CEA/DRF-CNRS/IN2P3Bvd.Henri Becquerel14076 CaenFrance CNRS IN2P3IPN LyonUniversitéLyon 169622 VilleurbanneFrance Department of Physics Nigde Omer Halisdemir University51240 NigdeTurkey Department of Physics University of YorkHeslingtonYork YO105DDUK

Pulse pile-up is a problem in nuclear spectroscopy and nuclear reaction studies that occurs when two pulses overlap and distort each other,degrading the quality of energy and timing *** methods have been used for pile-up rejection,both digital and analogue,but some pile-up events may contain pulses of interest and need to be *** paper proposes a new method for reconstructing pile-up events acquired with a neutron detector array(NEDA)using an one-dimensional convolutional autoencoder(1D-CAE).The datasets for training and testing the 1D-CAE are created from data acquired from the *** new pile-up signal reconstruction method is evaluated from the point of view of how similar the reconstructed signals are to the original ***,it is analysed considering the result of the neutron-gamma discrimination based on charge comparison,comparing the result obtained from original and reconstructed signals.

关键词： 1D-CAE Autoencoder CAE Convolutional neural network(CNN) Neutron detector Neutron-gamma discrimination(NGD) Machine learning Pulse shape discrimination Pile-up pulse

Implementation of a double trigger condition system based on charge comparison and TOF measurement for the NEDA detector array

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Nuclear Science and Techniques 2025年第2期36卷 40-48页

作者： j.M.Deltoro A.Goasduff F.j.Egea V.González A.Gadea R.M.Pérez-Vidal I.Lazarus M.Kogimtzis L.McNicholl M.Palacz G.jaworski j.j.Valiente-Dobón j.Nyberg S.Casans A.E.navarro-Antón E.Sanchis A.Boujrad E.Clément T.Hüyük R.Illicachi O.Stezowski V.Modamio Department of Electronic Engineering University of ValenciaBurjassotValenciaSpain Istituto Nazionale di Fisica Nucleare Laboratori Nazionali di LegnaroLaboratori Nazionali di LegnaroLegnaroPadovaItaly Instituto de Física Corpuscular CSIC-Universidad de ValenciaCSIC-Universidad de Valencia46980 PaternaValenciaSpain Science and Technology Facilities Council DaresburyUK Heavy Ion Laboratory University of Warsaw02-093 WarsawPoland Department of Physics and Astronomy Uppsala UniversityUppsalaSweden Grand Accélérateur National d’Ions Lourds(GANIL) CEA/DRF-CNRS/IN2P3CEA/DRF-CNRS/IN2P3CaenFrance Universitéde Lyon UniversitéLyon-1CNRS/IN2P3UMR5822IP2IIP2I4 Rue Enrico Fermi69622 Villeurbanne CedexFrance Department of Physics University of Oslo0316 OsloNorway

The NEutron Detector Array(NEDA)is designed to be coupled to gamma-ray spectrometers to enhance the sensitivity of the setup by enabling reaction channel selection through counting of the evaporated *** article presents the implementation of a double trigger condition system for NEDA,which improves the acquisition of neutrons and reduces the number of gamma rays *** independent triggers are generated in the double trigger condition system:one based on charge comparison(CC)and the other on time-of-flight(TOF).These triggers can be combined using OR and AND logic,offering four distinct trigger *** developed firmware is added to the previous one in the Virtex 6 field programmable gate array(FPGA)present in the system,which also includes signal processing,baseline correction,and various trigger logic *** performance of the trigger system is evaluated using data from the E703 experiment performed at *** four trigger modes are applied to the same data,and a subsequent offline analysis is *** is shown that most of the detected neutrons are preserved with the AND mode,and the total number of gamma rays is significantly *** with the CC trigger mode,the OR trigger mode allows increasing the selection of *** addition,it is demonstrated that if the OR mode is selected,the online CC trigger threshold can be raised without losing neutrons.

关键词： Neutron detector Neutron-gamma discrimination Pulse shape analysis Time-of-flight Charge comparison

Elenoside increases intestinal motility

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World journal of Gastroenterology 2006年第44期12卷 7143-7148页

作者： E navarro Sj Alonso R navarro j Trujillo E jorge Department of Pharmacology Faculty of Medicine University of La Laguna 38071 La Laguna Apdo. 55 Tenerife Canary Islands Spain Department of Medical and Chirurgical Sciences University of Las Palmas Gran Canaria Canary Islands Spain Centro de Productos Naturales y Agrobiologia CSIC Tenerife Canary Islands Spain

AIM： TO study the effects of elenoside, an arylnaphthalene lignan from justicia hyssopifolia, on gastrointestinal motility in vivo and in vitro in rats. METHODS： Routine in vivo experimental assessments were catharsis index, water percentage of boluses, intestinal transit, and codeine antagonism. The groups included were vehicle control （propylene glycol-ethanolplant oil-tween 80）, elenoside （i.p. 25 and 50 mg/kg）, cisapride （i.p. 10 mg/kg）, and codeine phosphate （intragastric route, 50 mg/kg）. In v/tro approaches used isolated rat intestinal tissues （duodenum, jejunum, and ileum）. The effects of elenoside at concentrations of 3.2 ×10^4, 6.4 ×10^4 and 1.2 ×10^3 mol/L, and cisapride at 10^6 mol/L were investigated. RESULTS： Elenoside in vivo produced an increase in the catharsis index and water percentage of boluses and in the percentage of distance traveled by a suspension of activated charcoal. Codeine phosphate antagonized the effect of 25 mg/kg of elenoside. In vitro, elenoside in duodenum, jejunum and ileum produced an initial decrease in the contraction force followed by an increase. Elenoslde resulted in decreased intestinal frequency in duodenum, jejunum, and ileum. The in vitro and in vivo effects of elenoside were similar to those produced by cisapride. CONCLUSION： Elenoside is a lignan with an action similar to that of purgative and prokinetics drugs. Elenoside, could be an alternative to cisapride in treatment of gastrointestinal diseases as well as a preventive therapy for the undesirable gastrointestinal effects produced by opioids used for mild to moderate pain.

关键词： Elenoside Gastrointestinal motility, Smail intestine preparation

Coffee Leaf Rust(Hemileia vastatrix)Disease in Coffee Plants and Perspectives by the Disease Control

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Phyton-International journal of Experimental Botany 2024年第5期93卷 923-949页

作者： Alexis Salazar-navarro victor Ruiz-Valdiviezo jose joya-Dávila Daniel Gonzalez-Mendoza Instituto de Ciencias Agrícolas de la Universidad Autónoma de Baja California(ICA-UABC) Nuevo LeónBaja California21705México Laboratorio de Biología Molecular del Instituto Tecnológico Nacional de Tuxtla Gutierrez(TecNM) Tuxtla GutierrezChiapas29050México Facultad de Ciencias Agronómicas Campus V.Universidad Autónoma de Chiapas(UNACH) VillafloresChiapas30470México

Coffee Leaf Rust(CLR)is caused by Hemileia vastatrix in Coffea *** is one of the most dangerous phytopathogens for coffee plantations in terms of coffee productivity and coffee cup *** this review,we resume the problem of CLR in Mexico and the pathogenesis of *** review abord plant-pathogen interactions which lead a compatible or incompatible interactions and result in CLR disease or resistance,*** review abord Coffea *** response pathways involved in *** ***,current measures to control *** proliferation and germination were aborded focused on phytosanitary actions,and biological and chemical ***,new trendlines to reduce the impact of CLR as nanoparticles and nanotechnology were analyzed.

关键词： Coffee leaf rust Coffea arabica pathogenesis nanoparticles biological control

History of pseudomyxoma peritonei from its origin to the first decades of the twenty-first century

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World journal of Gastrointestinal Surgery 2019年第9期11卷 358-364页

作者： Francisco j Morera-Ocon Clara navarro-Campoy Department of General Surgery Hospital General de RequenaValencia 46340Spain Department of Gynecology and Obstetrics Hospital 9 OctubreValencia 46340Spain

Pseudomyxoma peritonei(PMP)is a disease surrounded by misunderstanding and *** about the etymology of pseudomyxoma is useful to remove the ambiguity around that *** word pseudomyxoma derives from pseudomucin,a type of *** was first described in a case of a woman alleged to have a ruptured pseudomucinous cystadenoma of the ovary,a term that has disappeared from today’s classifications of cystic ovarian *** is known today that in the majority of cases,the origin for PMP is an appendiceal neoplasm,often of low histological ***,ovarian tumors are wrongly being considered a significant recognized etiology of *** classification continues to be under discussion,and experts’panels strive for *** is also under discussion,and it is shown in this review that there is a long-standing historical reason for *** is the main tool in the treatment armamentarium for PMP,and the only therapy with potential curative option.

关键词： Pseudomyxoma peritonei Pseudomucin Appendiceal neoplasm Hyperthermic intraperitoneal chemotherapy