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Functional Roux-en-Y Gastric Bypass (F-RYGB), with Preservation of Duodenal Access: Report of Two Revisional Cases of Sleeve Gastrectomy

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Surgical Science 2024年第3期15卷 135-158页

作者： victor Ramos Mussa Dib Carlos Augusto Scussel Madalosso Paulo Reis Esselin de Melo Rui Ribeiro Paula Volpe Carlos Eduardo Domene victor Dib Institute Manaus Brazil Gastrobese Clinic Passo Fundo Brazil Paulo Reis Institute of Bariatric Surgery Goi&#226nia Brazil Alfredo Nasser University Center (UNIFAN) Goi&#226nia Brazil Lusíadas Amadora Hospital Lisboa Portugal Integrated Center for Advanced Medicine (CIMAMED) S&#227o Paulo Brazil

Objective: This case report aimed to demonstrate a possible neuromuscular effect of Latarjet nerves transection or truncal vagotomy, in association with sleeve gastrectomy plus antrojejunostomy, in order to reproduce a Roux-en-Y gastric bypass (RYGB) mechanistic principles, in patients with previous Sleeve Gastrectomy (SG) who had had weight regain, with or without concomitant gastroesophageal reflux disease (GERD). Background: Sleeve gastrectomy (SG) is one of the most frequently performed bariatric operations worldwide. Nevertheless, weight regain and gastroesophageal reflux disease (GERD) have been consistently demonstrated, in association with this technique, which may require a revisional procedure. RYGB is an option in such a situation but, implies in gastrointestinal exclusions, which represents a shortcoming of this revision. Surpassing this inconvenient would be of great value for the patients. Methods: We describe herein two cases of SG revision for weight regain and GERD, with a follow-up of one year. Gastroesophageal reflux disease was evaluated by validated questionnaire, upper endoscopy, seriography, high resolution manometry (HRM) and impedance pHmetry (I-pHmetry), in the pre and postoperative periods. A re-Sleeve Gastrectomy with antrojejunal anastomosis was done in both cases, after informed consents. The Latarjet nerves were transected in one case, due to a bleeding in the left gastric vessels and a truncal vagotomy was required in the other, to appropriately treat an associated hiatal hernia. Results: In the postoperative evaluation it was observed a pyloric spasm in both cases, during seriography and endoscopy, kept until the one-year follow-up. There was unidirectional contrast flow to the gastrointestinal anastomosis, filling the jejunal limb, in radiologic contrast study. No contrast passed through the pylorus. Nonetheless, the duodenum was kept endoscopically accessible. In the one-year evaluation, weight loss was adequate and GERD resolution

关键词： Roux-en-Y Gastric Bypass Sleeve Gastrectomy Jejuno Gastric Bypass Vagus Nerve Vagotomy Bariatric Surgery

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Transplacental transmission of dengue infection

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World Journal of Virology 2024年第3期13卷 1-6页

作者： Leonel Eslatkin Aguilar Zambrano victor Manuel Vasquez Zevallos Gita Vita Soraya Lola Ayu Istifiani Syafrizal Aji Pamungkas Zulvikar Syambani Ulhaq Department of Medicine Technical University of ManabiManabi 130101Ecuador Department of Pediatrics Verdi Cevallos Balda HospitalPortoviejo 130105Ecuador Department of Biochemistry Hasanuddin UniversityMakassar 90245Indonesia Department of Nutrition Faculty of Health SciencesBrawijaya UniversityMalang 65100Indonesia Clinic of Yayasan Dana Sosial Al Falah Malang 65100Indonesia Research Center for Preclinical and Clinical Medicine National Research and Innovation Agency Republic of IndonesiaCibinong 16911Indonesia

We specifically addressed the persistent challenge of dengue in endemic regions,highlighting the potential seriousness of dengue infection through vertical *** dengue transmission has been well documented,particularly in hyper-endemic regions,including ***,we present a neonate diagno-sed with congenital dengue and review similar cases from previously published *** congenital dengue is commonly infected with severe serotypes of DENV(DENV-1 and DENV-2)infections,favorable outcomes are generally observed.

关键词： Vertical transmission Transplacental Congenital dengue Infectious disease DENV

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Quantitative Assessment of Liver Fibrosis by Elastography in Patients with Chronic Liver Disease: A Cross-Sectional Study in Lomé (Togo)

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Open Journal of Radiology 2024年第2期14卷 42-54页

作者： Massaga Dagbe Bidamin N’timon Sonia Ekembe Rafiou El-Hadji Yakoubou Pihou Gbande Lantam Sonhaye Lama Kegdigoma Agoda-Koussema Komlanvi victor Adjenou Department of Radiology and Medical Imaging Kara University Hospital Kara Kara Togo Department of Radiology and Medical Imaging Lom University Hospital Lome Togo Department of Hpato-gastroenterology Kara University Hospital Kara Togo Department of Radiology and Medical Imaging Sokod Regional Hospital Sokode Togo Department of Internal Medicine Kara University Hospital Kara Togo

Aim: To describe the two-dimensional elastographic profile according to the Shearwave (2D-SWE) technique in patients with chronic liver disease in Lom. Materials and method: Cross-sectional, descriptive study conducted over seven month at the Autel dElie Clinic in Lom, from January to August 2022, on adult patients with chronic liver disease who underwent abdominal ultrasound coupled with two-dimensional elastography. Results: The sample size was 54 patients. The mean age of the patients was 33 12 years, with extremes of 18 and 66 years. Patients aged 30 years or less accounted for 48.1% (n = 26). All patients (n = 54) had at least one transaminase assay with a mean of 69.3 78.3 IU/l (AST) and 59.3 82.8 IU/l (ALT). There was no statistically significant association between the biological parameters and the presence of fibrosis. Viral liver disease was the main cause, accounting for 81.5% (n = 44) of cases, with no significant association with the degree of fibrosis. Ultrasound revealed a dysmorphic liver (57.4%;n = 31) and portal hypertension (18.5%, n = 10). Fibrosis stages F1, F2 and F4 accounted for (48.1%, n = 26), (24.1%, n = 13) and (13%, n = 7) of cases respectively. Liver dysmorphia was significantly associated with the presence of fibrosis (p = 0.012) and portal hypertension was significantly associated with the degree of fibrosis (p = 0.0063). Conclusion: Assessment of liver fibrosis in patients with chronic liver disease using 2D-SWE elastography is essential for patient follow-up.

关键词： Hepatic Fibrosis 2D-SWE Elastography Chronic Liver Disease Lomé

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Study of boundary layer characteristics during the landfalling of a Nisarga cyclone

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Tropical Cyclone Research and Review 2024年第2期13卷 55-71页

作者： Rani P.Pawar Prajna Priyadarshini T.Dharmaraj Dada P.Nade Mahendra N.Patil Omkar M.Patil N.Jeni victor Sambhaji M.Pawar D.G.Kanase Sunil D.Pawar Indian Institute of Tropical Meteorology Ministry of Earth SciencesPuneIndia Department of Physics Bharati Vidyapeeth’s Dr.Patangrao Kadam Mahavidyalaya(Shivaji University Kolhapur)SangliIndia KSK Geomagnetic Research Laboratory IIGPrayagrajAllahabadIndia Department of Physics Sanjay Ghodawat University KolhapurIndia

One of the most important parameters in meteorology is the mean wind proﬁle in the tropical cyclone boundary *** vertical proﬁle of wind speed and wind direction were measured during the period of the Nisarga cyclone from May 31st,2020,to June 5th,2020,using the newly installed Phased Array Doppler Sodar system at the Center for Space and Atmospheric Science(CSAS),Sanjay Ghodawat University,Kolhapur(16.74◦N,74.37◦E;near India's western coast).Our analysis revealed that the maximum mean wind speed was 17 m/s on June 3,2020,at 10:00 *** also shows the change in wind direction from southwest to southeast on June 2 and 3,*** high-resolution reanalysis data in the domain,0–25◦N,65–110◦E,during the period from May 31st to June 5th,2020,revealed the variation of the atmospheric pressure of the Nisarga cyclone from 1000 to 1008 hPa,sea surface temperature(SST)between 30◦C and 31◦C,outgoing longwave radiation(OLR)between 100 and 240 Wm-2,wind speed between 3 and 15 m/s,and low values of vertical wind shear(VWS)were observed to the north of Nisarga *** observations may provide more insights for the study of boundary layer turbulence during cyclonic activities.

关键词： Doppler Sodar Tropical cyclone Atmospheric boundary layer Vertical turbulence intensity

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Soil Physico-Chemical Properties and Different Altitudes Affect Arbuscular Mycorrhizal Fungi Abundance and Colonization in Cacao Plantations of Cameroon

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American Journal of Plant Sciences 2024年第2期15卷 57-82页

作者： Franklin Tounkam Ketchiemo Beaulys Fotso Astride Stéphanie Mouafi Djabou victor Jos Eyamo Evina Japhet Youri Essambita Franck Maxime Ewane Tang Nicolas Niemenak Laboratory of Plant Physiology and Biochemistry Department of Biological Sciences Higher Teacher Training College University of Yaounde I Yaounde Cameroon Department of Plant Biology Faculty of Sciences University of Yaounde I Yaounde Cameroon Faculty of Agronomy and Agricultural Sciences Bafia Annex University of Dschang Dschang Cameroon Applied Biotechnology Engineering Laboratory Department of Agriculture and Agropastoral Higher Teacher Training College University of Ebolowa Ebolowa Cameroon Plant Physiology Improvement Unit Laboratory of Biotechnology and Environment Department of Plant Biology Faculty of Sciences University of Yaounde I Yaounde Cameroon

This study aims to investigate the abundance of AMF according to soil properties and altitudes in different cacao plantations of Cameroon. Physico-chemical analyses were made on soil samples collected from three agro-ecological zones. Soil samples were also used to evaluate directly the AMF abundance following the various altitudes and after trapping by sorghum plant. The results showed that soil properties, AMF spore abundances and colonization fluctuated significantly at different altitudes. The most represented texture was sandy loam. The bimodal zone presented a homogeneous texture (sandy loam) in all its localities. Cacao soil chemical characteristics showed that, the highest nitrogen rate (0.47%;p 0.05, Scott-Knott test) was recorded at Melong in a monomodal zone while Tonga in the Western highlands displayed the lowest rate (0.13%). Soil P concentration was significantly high in monomodal zones (Mbanga and Melong). Soil pH level indicated that the soil from Tonga in the Western highlands was neutral (pH = 6.67), and soils of other localities under study were acidic with the lowest (4.75) pH level recorded at Melong in a monomodal zone. In soil samples, the highest spore density (1.03 spores/g soil) was observed at Ntui in Bimodal zone, while the lowest spore density (0.26 spores/g soil) was observed at Bafang in the Western highlands. Root colonization showed that the sample from Bokito in a bimodal zone displayed the best frequency of mycorrhization (86.11%) while the sample from Bafang in the Western highlands recorded the lowest (27.11%). The PCA analysis highlighted that available phosphorus, pH and altitude all strongly correlated with AMF root colonization ability and can be used as a predictor of AMF colonization ability in cacao rhizosphere.

关键词： Agroecological Zone Altitude Variations Arbuscular Mycorrhizal Fungi Soil Properties Theobroma cacao

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Cystic Degeneration of Uterine Myoma Simulating Ovarian Cancer in Postpartum: A Case Report at the Teaching Hospital of Angre

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Open Journal of Obstetrics and Gynecology 2024年第9期14卷 1522-1528页

作者： Roland Adjoby Ndrin Denis Effoh Soh victor Koffi Okoin Paul José Loba Ngolo Alassane Soro Yapo Privat Akobé Ramata Kouakou-Kouraogo Michelle Gadji Obstetric Gynecology Department of Angres Teaching Hospital Abidjan Cte dIvoire

The transformation of uterine fibroids is common in relation to their development. Giant forms of cystic degeneration are rare. They raise diagnostic difficulties with other pelvic tumors, such as ovarian tumors and leiomyosarcomas. Magnetic resonance imaging specifies the original organ, the volume and the main relationships of fibromyoma with adjacent structures. The diagnosis of certainty is based on laparotomy coupled with histology. The authors illustrate these difficulties by observing a giant cystic degenerative fibroma in a 26-year-old G1P1 woman in the postpartum period.

关键词： Fibromyoma Uterine Neoplasia Pelvic Tumor MRI

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Proximate analyses,in vitro antioxidant activity and GC-MS analyses of fermented Pentaclethra macrophylla seeds

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Life Research 2024年第3期7卷 2-8页

作者： Ikechukwu Okoro Parker Joshua Innocent Okagu Christian Amah Nnamani Ikenna Nene Chiaka-Onyemeze Emeka Anaduaka David Obasi Prince Okoroh Daniel Orieke victor Ogugua Department of Medical Biochemistry College of Health SciencesDavid Umahi Federal University of Health SciencesUburuNigeria Department of Biochemistry University of NigeriaNsukkaNigeria Department of Biochemistry State University of Medical and Applied SciencesIgbo-EnoNigeria Department of Medical Laboratory Sciences State University of Medical and Applied SciencesIgbo-EnoNigeria

The present study assessed the proximate composition,in vitro antioxidant activity and GC-MS analyses of fermented Pentaclethra macrophylla seeds extract(FPMSE).The in vitro antioxidant activity was assessed using 2,2-diphenyl-1-picrylhydrazl(DPPH)while Gas Chromatography-Mass Spectrophotometry(GC-MS)technique was used to identify the volatile compounds in *** revealed a dose dependent percentage inhibition of the extract on DPPH *** composition of FPMSE constitutes respectively;ash(0.33±0.12%),protein(2.19±0.08%),fats and oil(80.60±0.00%),carbohydrate(16.88±0.00%)while moisture and fibre were not ***,the pulverised sample constitute respectively;ash(1.27±0.58%),protein(10.51±0.60%),moisture(8.27±0.12%),fats and oil(32.33±0.12%),fibre(7.27±0.12%)and carbohydrate(40.35±0.00%).GC-MS analyses revealed fourteen(14)fatty acids including Octadecanoic acid(1.95%),Benzyloxymethylimine(43.89%),2-Allylpent-4-enoic acid benzyl ester(26.25%),Hexadecanoic acid,methyl ester(1.09%),Oleic Acid(0.25%),9,12-Octadecadienoic acid,methyl ester(Omega-6-fatty acid)(1.52%).The bioactive compounds identified in FPMSE could contribute to the pharmacological properties of *** seeds and hence,could be of considerable interest for the development of new drugs.

关键词： Pentaclethra macrophylla in vitro antioxidant GC-MS fatty acids

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Congenital Bilateral Proximal Radio-Ulnar Synostosis in a Nigerian Child

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Open Journal of Pediatrics 2024年第1期14卷 101-107页

作者： Alabi Ayobami Oyetunji Joel-Medewase victor Idowu Olalere Ayankemi Adenike Joel Iretiayo Titilolu Sayomi Bukola Adetutu Oladibu Olanike Taiye Adetoye Mayowa Mary Ashaolu Oluwakayode Joseph Department of Paediatrics and Child Health Ladoke Akintola University of Technology Ogbomoso Nigeria Department of Radiology Ladoke Akintola University of Technology Ogbomoso Nigeria Department of Radiology University College Hospital Ibadan Nigeria Department of Paediatrics and Child Health LAUTECH Teaching Hospital Ogbomoso Nigeria

Congenital radio-ulnar synostosis (CRUS) is a rare skeletal malformation of the upper limb and the most common congenital functional disorder of the elbow joint, causing limitation in forearm rotational movements, which may lead to difficulties with some activities of daily living. We reported a 4-year-old girl with congenital bilateral proximal radio-ulnar synostosis who presented with functional discomfort due to limitation of the prono-supination movements of the forearms and abnormal gestures when handling objects. She has clinical and radiological features of congenital radio-ulnar synostosis (CRUS). However, the parents declined corrective surgery because of wrong perception of the condition to be normal. This case highlighted the poor health seeking behavior and wrong illness perception prevalent in the developing countries.

关键词： Congenital Radio-Ulnar Synostosis Upper Limb Congenital Anomalies Pro-no-Supination

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L-Arginine Supplementation Mitigates Dichlorvos-Induced Haematocardiotoxicity, and Oxidative Stress in Male Wistar Rats

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Open Journal of Applied Sciences 2024年第7期14卷 1886-1903页

作者： Waidi Adeoye Saka Yusuff Dimeji Igbayilola Jabba Hamidu Lawan Taoheed Kolawole Muftaudeen Ridwanullahi Adejumo Tolulope Deborah Alu Mary Ikuomola Joshua Tinuade Ojelere victor Odufa Adegoke Department of Physiology College of Health Sciences Ladoke Akintola University of Technology Ogbomoso Oyo State Nigeria Department of Human Physiology College of Medicine and Health Sciences Baze University Abuja Nigeria Department of Biological Sciences Faculty of Computing and Applied Sciences Baze University Abuja Nigeria

Due to its toxicity, dichlorvos—a common organophosphate pesticide—poses significant risks to human health. This study utilized male Wistar rats to explore the potential protective effects of L-arginine supplementation against dichlorvos-induced toxicity, focusing on cardiotoxicity, haematotoxicity and oxidative stress. The rats were divided into four groups: Control, L-arginine (L), Dichlorvos (D), and L-arginine + Dichlorvos (L + D). Dichlorvos was administered to the D group, L-arginine (100 mg/kg) to the L group, and both L-arginine and dichlorvos to the L + D group. The study evaluated various parameters, including cardiovascular, oxidative stress markers, and haematological indices. Significant changes in haematological parameters such as haemoglobin (Hb), haematocrit (HCT), and red blood cell count (RBC) indicated haematotoxicity after dichlorvos administration. Additionally, elevated cardiac markers, including lactate dehydrogenase (LDH) and creatine kinase-MB (CK-MB), suggested cardiotoxic effects. Exposure to dichlorvos also resulted in decreased antioxidant enzyme levels and increased oxidative stress indicators like malondialdehyde (MDA). Remarkably, L-arginine supplementation mitigated the damage caused by dichlorvos. It normalized the altered haematological parameters, demonstrating its protective effect against haematotoxicity. The rise in cardiac markers was reduced with L-arginine supplementation, indicating protection against cardiotoxicity. Moreover, L-arginine significantly decreased oxidative stress, as evidenced by lower MDA levels and restored antioxidant enzyme activity. In conclusion, L-arginine supplementation in male Wistar rats showed promising protective effects against dichlorvos-induced cardiotoxicity, haematotoxicity and oxidative stress. This suggests that L-arginine may offer a beneficial intervention to mitigate the adverse effects of dichlorvos on blood and heart health, paving the way for potential treatments for pesticide poison

关键词： Dichlorvos L-Arginine Cardiovascular Function Haematological Parameters Oxidative Stress

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Sleeve Gastrectomy with Duodenal Transit Bipartition (S-DTB): Preliminary Results and Technical Aspects of Its Metabolic Structure

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Surgical Science 2024年第4期15卷 244-264页

作者： Paulo Reis Esselin de Melo Ricardo Zorron victor Ramos Mussa Dib Carlos Augusto Scussel Madalosso Rui Ribeiro Thonya Cruz Braga Paula Volpe Carlos Eduardo Domene Paulo Reis Institute Goiania GO Brazil Alfredo Nasser University Center (UNIFAN) Goiania GO Brazil Department of Bariatric and Metabolic Surgery CUF Descobertas Hospital Lisbon Portugal victor Dib Institute Manaus AM Brazil Gastrobese Clinic Passo Fundo RS Brazil Lusiadas Amadora Hospital Lisbon Portugal Clianest Group Renaissance Hospital Goiania GO Brazil Integrated Center for Advanced Medicine (CIMAMED) Sao Paulo Brazil

Obesity is a significant and escalating health issue both in Brazil and globally, with over 650 million overweight adults worldwide. The treatment of obesity can be performed clinically, endoscopically or surgically;surgical treatment proves to be safe and more effective in terms of weight loss and long-term maintenance. Objective: This study aimed to monitor the progress of weight loss and comorbidity control in patients undergoing sleeve gastrectomy with duodenal bipartition. Methods: This pilot project involved 8 patients divided into 2 arms. In the first arm, patients underwent sleeve gastrectomy with Roux-en-Y duodenoileal transit bipartition (S-RYDITB), while in the second arm, patients underwent sleeve gastrectomy with Roux-en-Y duodenojejunal transit bipartition (S-RYDJTB). Both procedures involved Roux-en-Y reconstruction without duodenal exclusion. In S-RYDITB, the duodenal-ileal anastomosis was performed 300 cm from the ileocecal valve (ICV), creating a 250 cm common channel and a 50 cm alimentary channel. In S-RYDJTB, a biliopancreatic loop was created 200 cm from the angle of Treitz, with a 1 m alimentary channel. Results: Five patients underwent the procedures, with one undergoing S-RYDITB and four undergoing S-RYDJTB. No adverse events such as hospitalizations, readmissions, reoperations, fistulas, bleeding, pulmonary embolism, diarrhea, dumping syndrome, or hypoglycemia occurred during the study period. The mean length of hospital stay was 2 days. The average BMI decreased from 37.27 kg/m2 preoperatively to 29.48 kg/m2 after 6 months. The significant percentage of weight loss was 21.22%, with excess weight loss of 63.6%. Ninety-five percent remission of comorbidities, including hypercholesterolemia, hypertriglyceridemia, diabetes, hypertension, steatosis, and pre-diabetes. Two patients underwent sleeve gastrectomy with duodenal bipartition using a single anastomosis. Conclusion: Duodenal switch surgery has gained worldwide recog

关键词： Obesity Bariatric Surgery Metabolic Surgery Duodenal Switch

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