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Spouses of patients with diabetes mellitus type 2 at increased risk of high blood glucose levels

Open Journal of Preventive Medicine 2013年第1期3卷 58-63页

作者： Ganiyu Lanre Yahaya Alero Ann Roberts victor akpan inem Department of Community Health & Primary Care College of Medicine University of Lagos Lagos Nigeria Department of Family Medicine Lagos State University Teaching Hospital Lagos Nigeria

Introduction: Diabetes mellitus type 2 is a growing threat in developing countries already burdened with high levels of infectious disease. Screening the general population has debatable advantages. This study aims to determine whether spouses of patients with diabetes mellitus have higher random blood glucose (RBG) levels as well as the benefit of RBG testing as a targetted screening tool. Methodology: The survey employed a cross-sectional comparative study of spouses’ of diabetics and non-diabetics attending the general out-patient department of the LagosStateUniversityTeaching Hospital (LASUTH), Ikeja. A modified WHO STEPS Surveillance Instrument and a one-touch Glucometer were used to collect data. Blood pressures and BMI were measured and correlated to blood glucose levels. Results: Prevalence of high RBG was found to be 7% among spouses of diabetics and 3.3% among spouses of non-diabetic patients. Mean RBG was 5.57 mmol/L and 7.7 mmol/L within the age group 40 - 49 years and 50 - 59 years respectively among spouses of diabetic patients compared to 5.4 mmol/L and 5.5 mmol/L within the same age group among the spouses non-diabetics. Spouses of patients with diabetes mellitus had higher systolic and diastolic blood pressures and BMI compared to spouses of non-diabetics. Conclusion: Being male, married to a diabetic patient, lower educational levels and higher body mass index are significantly associated with higher random blood glucose in the spouses of diabetic patients. Random blood glucose measurements are an effective screening tool and spouses of diabetic patients can benefit from targeted screening in controlled clinical settings.

关键词： Diabetes Mellitus Type 2 Non-Communicable Disease Random Blood Glucose Levels Glucose Intolerance Body Mass Index Blood Pressure

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Some aspects of the biology of the female blue crab Callinectes amnicola(De Rocheburne)from the Cross River estuary,Nigeria

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Journal of Coastal Life Medicine 2015年第4期 259-264页

作者： Eyo victor Oscar akpan Michael Mfon Udoh Ifiok Solomon Fisheries and Aquaculture Unit Institute of OceanographyUniversity of CalabarP.M.B.1115CalabarCross River StateNigeria Fisheries Department Ministry of Agriculture and Natural ResourcesP.M.B.1113UyoAkwa Ibom StateNigeria Zoology and Environmental Biology Programme University of CalabarP.M.B.1115CalabarCross River StateNigeria

Objective:To investigate some important aspects of the biology of Callinectes amnicola(***)such as fecundity,carapace length-weight relationship,condition factor and carapace length frequency distribution from the Cross River estuary,***:A total of one hundred and twenty ovigerous females of ***,freshly caught with basket traps,lift net trap,and gill net were collected from the catches of the artisanal fisheries in the study area between June 2012 and May ***,carapace length-weight relationship,condition factor and carapace length frequency distribution were determined and analyzed following standard ***:Fecundity(F)ranged between 73090 eggs for crab of carapace length 8.1 cm and total weight 34 g and 809450 eggs for crab of carapace length 16.1 cm and total weight 395 g with a mean of 311808.93±17693.94 *** was a positive significant relationship between fecundity and carapace length,total weight and condition factor as follows:F=6839.7CL^(1.4403)(r^(2)=0.2145,P<0.05),F=15302TW^(0.5798)(r^(2)=0.4079,P<0.05),F=147255K^(0.2788)(r=0.2717,r^(2)=0.0738,P<0.05).A significant linear relationship between carapace length and weight of *** is given by the equation:Log W=2.0447LogL–0.1389(r^(2)=0.3357,P<0.05).The crab exhibited a negative allometric growth pattern(b=2.0447).Condition factor ranged between 21.48 to 104.95 with a mean value of 47.21±*** carapace length frequency distribution showed a unimodal class size ***:Findings of this study is crucial in assessing the population dynamics and development of management strategies of the the Blue crab,*** from the estuary such as mesh size regulation,fishing season and fishing ground regulation in the Cross River ***,findings of this study will be useful in evaluation of the aquaculture potential of the Blue crab ***,which is a valuable shell fish for the inhabitants estuary.

关键词： Callinectes amnicola Cross River estuary Fecundity Carapace length-weight parameters Condition factor Carapace length-frequency distribution

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香烟主流烟雾多环芳烃检测及其在职业医学中的应用研究

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中国职业医学 2007年第4期34卷 320-322页

作者：黄曙海 akpan victor LODOVICI Maura DOLARA Piero 广西壮族自治区疾病预防控制中心广西南宁530021 意大利佛罗伦萨大学

目的建立检测香烟主流烟雾多环芳烃(PAH)测定方法,评价吸烟对PAH作业工人职业危害。方法采用标准化吸烟机工作程序收集主流烟雾中的颗粒物,经二甲基甲酰胺溶液、异辛烷分步提取,硅胶柱净化,然后用高效液相色谱技术分离检测主流烟雾中PAH... 详细信息

目的建立检测香烟主流烟雾多环芳烃(PAH)测定方法,评价吸烟对PAH作业工人职业危害。方法采用标准化吸烟机工作程序收集主流烟雾中的颗粒物,经二甲基甲酰胺溶液、异辛烷分步提取,硅胶柱净化,然后用高效液相色谱技术分离检测主流烟雾中PAH9个组分。结果在选定条件下,该方法具有良好的线性、精密度和准确度。应用于实际样品检测,20个品牌国产香烟主流烟雾中总PAH平均含量为714.8ng/支。结论本方法适合于检测香烟主流烟雾中PAH含量;建立了将香烟主流烟雾PAH含量换算为8h平均吸入浓度从而评价吸烟对PAH作业工人职业危害的影响。

关键词：香烟主流烟雾 PAH 高效液相色谱

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Anal Cancer in a HIV Sero-Positive Bisexual Bachelor—A Case Report and Literature Review

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Case Reports in Clinical Medicine 2018年第12期7卷 601-607页

作者： victor Nwagbara M. E. Asuquo J. A. Ashindoitiang S. O. akpan Department of Surgery University of Calabar Calabar Nigeria

Anal cancer, especially squamous cell carcinoma (SCC) variety, is evolving with rising incidence globally. This is due to the increasing adoption of risky life styles and social habits even in populations with rare occurrences previously. This case report aims to expose risk factors exhibited by a patient recently managed for anal cancer in our facility before his demise. Early exposure to bisexual orientation, receptive anal intercourse and multiple sexual partners, are notable high risk factors for the development of anal SCC. The permissive role of smoking, illicit drug and alcohol use enhances the disease occurrence. Acquisition of human immune-deficiency virus (HIV) sero-positive status further reduces the body’s immune competence and enhances early age of onset as well as accelerates development of anal SCC. Proper history exploring the risk factors, physical/anorectal examination and histological analysis, are vital for proper diagnosis and staging which guides appropriate treatment with chemo-radiation as mainstay.

关键词： Anal Cancer Bisexual Human Immune-Deficiency Virus Sero-Positive Status Squamous Cell Carcinoma

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Blood Pressure Control among Adult African Chronic Kidney (CKD) Patients—How Close Are We to Target?

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Open Journal of Nephrology 2020年第1期10卷 50-59页

作者： Effiong Ekong akpan Udeme Ekpenyong Ekrikpo Aniema Isaac-Assam Udo Aniedi victor Umoh Idongesit Odudu Umoh Department of Internal Medicine University of Uyo Uyo Nigeria

Background: Chronic kidney disease (CKD) is usually progressive, often resulting in end-stage renal disease (ESRD). The two most common causes of renal disease, hypertension and diabetes mellitus contribute greatly to the mobility and mortality associated with CKD. It has been found that lowering BP is effective in reducing cardiovascular events in patient with a moderate reduction in GFR and in those with ESRD on dialysis. The aim of this study was to assess blood pressure control among adult African CKD patients. Method: The case notes of chronic kidney patients who assess care in the renal unit of our Teaching Hospital were retrieved for the study after obtaining informed consent from the ethical unit of the hospital. To be eligible for the study, the patient, must have been attending the renal clinic and on anti-hypertensives for a minimum period of 6 months. Results: Eighty-seven CKD patients (46 males and 41 females) with a mean age of 50.9 ± 13.3 years. The proportion of patients who achieved blood pressure control was 13.79% (95% CI 7.34% - 22.85%). Among the pre-dialysis patients, BP control was achieved in 13.64% compared to 14.29% among the patients on dialysis. Nineteen (21.84%) of the patients were on one blood pressure lowering agent;26 (29.89%) on two;33 (37.93%) on three;7 (8.05%) on four and 2 (2.30%) on five. Conclusion: Blood pressure control among African adult CKD patients is difficult with many of them requiring more than two antihypertensive drugs.

关键词： Blood Pressure Control. CKD Africa

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国产香烟主流烟雾中多环芳烃的含量

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环境与健康杂志 2006年第1期23卷 46-48页

作者：黄曙海葛宪民汤俊豪 akpan victor LODOVICI Maura DOLARA Piero 广西疾病预防控制中心广西南宁530021 广西职业病防治研究所广西南宁530021 意大利佛罗伦萨大学药理系意大利佛罗伦萨50139

目的检测20种主要国产品牌香烟主流烟雾中多环芳烃与焦油含量,并分析其是否有相关关系。方法按ISO国际标准吸取香烟主流烟雾中颗粒物,提取颗粒物中的多环芳烃,高效液相法测定荧蒽(FLUO),芘(pyrene熏PY),苯并(g熏h熏j)(BGP),苯并(a)蒽眼B... 详细信息

目的检测20种主要国产品牌香烟主流烟雾中多环芳烃与焦油含量,并分析其是否有相关关系。方法按ISO国际标准吸取香烟主流烟雾中颗粒物,提取颗粒物中的多环芳烃,高效液相法测定荧蒽(FLUO),芘(pyrene熏PY),苯并(g熏h熏j)(BGP),苯并(a)蒽眼B穴a雪A演,(CRY)熏苯并(a)芘眼B穴a雪P演,苯并(b)荧蒽眼B(b)F演,苯并(k)荧蒽眼B(k)F演,二苯并(a熏h)蒽(DBA)9种多环芳烃含量,并检测烟雾中焦油、尼古丁含量。结果20种主要品牌香烟主流烟雾中多环芳烃主要成分含量均值从高到低依次为芘,荧蒽,CRY,苯并(a)蒽,二苯并(a熏h)蒽,苯并(a)芘,苯并(g熏h熏j),苯并(b)荧蒽熏苯并(k)荧蒽。总PAHs平均含量为714.8ng/支,其中芘、荧蒽等非致癌性组分占总PAHs的93%;致癌性多环芳烃平均含量为89.4ng/支,以苯并(a)芘和二苯并(a熏h)蒽为主要成分。总PAHs、致癌性PAHs含量与焦油含量的相关系数和P值分别为0.647,0.002,0.554,0.011。结论国产香烟主流烟雾中均可检出9种多环芳烃,总PAHs、致癌性PAHs含量与焦油含量呈正相关,提示焦油可作为估计烟雾中致癌多环芳烃含量、评价健康危害的指标。

关键词：焦油多环芳烃香烟色谱法,高压液相

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