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Small intestinal bacterial overgrowth in inactive Crohn's disease:Influence of thiopurine and biological treatment

World Journal of Gastroenterology 2014年第38期20卷 13999-14003页

作者： Cristina Sánchez-Montes vicente ortiz Guillermo Bastida Ester Rodríguez María Yago Belén Beltrán Mariam Aguas Marisa Iborra vicente Garrigues Julio Ponce Pilar Nos Gastroenterology Unit Hospital Universitari i Politécnic La Fe

AIM: To investigate the influence of thiopurines and biological drugs on the presence of small intestinal bacterial overgrowth (SIBO) in patients with inactive Crohn’s disease (CD).

关键词： Crohn’ s disease Bacterial overgrowth Thiopurines Biologics Inflammatory bowel disease

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Discovery of gargantulides B and C,new 52-membered macrolactones from Amycolatopsis *** absolute stereochemistry of the gargantulide family

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Organic Chemistry Frontiers 2022年第2期9卷 462-470页

作者： Daniel Carretero-Molina Francisco Javier ortiz-López Tetiana Gren Daniel Oves-Costales Jesús Martín Fernando Román-Hurtado Tue Sparholt Jorgensen Mercedes de la Cruz Caridad Díaz Francisca vicente Kai Blin Fernando Reyes Tilmann Weber Olga Genilloud Fundación MEDINA Centro de Excelencia en Investigación de Medicamentos Innovadores en AndalucíaAvda.del Conocimiento 3418016 ArmillaGranadaSpain The Novo Nordisk Foundation Center for Biosustainability Technical University of DenmarkKemitorvetbuilding 2202800 Kgs.LyngbyDenmark

Gargantulides B and C,two new and highly complex 52-membered glycosylated macrolactones,were isolated from Amycolatopsis *** CA-230715 during an antibacterial screening *** structures of these giant macrolides were elucidated by 2D NMR spectroscopy and shown to be related to gargantulide A,although containing additional β-glucopyranose and/orα-arabinofuranose monosaccharides separately attached to their *** sequencing allowed the identification of a strikingly large 216 kbp biosynthetic gene cluster,among the largest type Ⅰ PKS clusters described so far,and the proposal of a previously unreported biosynthetic pathway for gargantulides *** absolute configurations of gargantulides B and C were assigned based on a combination of NMR and bioinformatics analysis of ketoreductase and enoylreductase domains within the multimodular type Ⅰ *** addition,the absolute stereochemistry of gargantulide A has now been revised and *** B and C display potent antibacterial activity against a set of drug-resistant Gram-positive bacteria and moderate activity against the clinically relevant Gram-negative pathogen Acinetobacter baumannii.

关键词： absolute membered backbone

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Microstructural Characterization of Large Area C<sub>60</sub>Films Obtained by Conventional Microwave Oven Irradiation

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World Journal of Nano Science and Engineering 2012年第4期2卷 213-218页

作者： Jacobo Martínez-Reyes Lucia Graciela Díaz Barriga-Arceo Luis Rendón-Vazquez Reynaldo Martínez-Guerrero Néstor Romero-Partida Eduardo Palacios-González vicente Garibay-Febles Jaime ortiz-López IMP-Molecular Engineering Program México City México National Polytechnic Institute (IPN) ESFM UPALM México City México National Polytechnic Institute (IPN) ESIQIE UPALM México City México ROMFER S.A. de C.V. México City México UNAM-FCiencias México City México

In the present work the synthesis of C60 produced in a conventional microwave oven from the decomposition of camphor resin is reported. The polycrystalline structure of the sample was determined by X-Ray Diffraction (XRD), the sample showed several phases, the main phase corresponds to fullerene C60 ordered in a Face-Centered Cubic structure (FCC), with two more structures: one orthorhombic system and the other the monoclinic system coexisting also with graphite 2H phase. It was observed in a Scanning Electron Microscopy (SEM), that the sample formed thin films of stacked carbon. Whereas in a High Resolution Transmission Electron Microscopy (HRTEM), measurements in Bright Field mode revealed that the main phase of the material is C60 ordered in FCC structure and the elemental composition and atomic bonding state can be determined by analyzing the energy with the electron microscope by Elesctron Energy- Loss Spectroscopy (EELS), technique allowed confirm all the phase C60 established with XRD observations.

关键词： Microwave-Assisted Synthesis Carbon Film Fullerene

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Comparison of Interpolation Methods for the Study of Forest Variables Using a Geographic Information System

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Journal of Agricultural Science and Technology(B) 2011年第3期1卷 428-436页

作者： I. Romero-Toro-Gascuena S. Sastre-Merino J. vicente-Guillen E. Ayuga-Tellez M. J. Garcia-Garcia C.Gonzalez-Garcia M. A. Grande-ortiz Technical University of Madrid Madrid 28040 Spain

Interpolation methods in ArcGIS_ESRI Geostatistical Analyst tool allow obtaining unknown values at unsampled points from observed data and generating continuous surfaces. In this paper, forest data variables as tree height and diameter measured in two plots in Central Mountains in Spain. These data were georeferenced to obtain maps that can visualize the spatial variability of these forest variables. In order to evaluate the best interpolation method that could adequately explain the spatial variability of those variables, two interpolation methods were studied： inverse results was made by means of statistical methods to analyze distance weighted （IDW） and Ordinary Kriging （OK）. A comparison of residuals. Results with the kriging method were slightly better.

关键词： GIS tools interpolation methods spatial data models geostatistical techniques.

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