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Postglacial incision-infill cycles at the Borisoglebsk Upland: Correlations between interfluve headwaters and fluvial network

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international Soil and Water Conservation Research 2019年第2期7卷 184-195页

作者： Yuliya V.Shishkina Ekaterina V.Garankina Vladimir R.Belyaev ilya G.Shorkunov Pavel V.Andreev Aleksey i.Bondar vi.tori. i.potapova Tatiana A.Verlova Faculty of Geography Department of Geomorphology and Palaeogeography and Laboratory for Soil Erosion and Fluvial ProcessesLomonosov Moscow State UniversityLeninskie Gory1Moscow 119991Russia institute of Geography Department of Soil Geography and EvolutionRussian Academy of SciencesStaromonetnyj Lane29Moscow 119017Russia institute of Earth Sciences of Saint-Petersburg State University St.PetersburgUniversitetskaya nab.7-9 199034Russia

The article discusses postglacial landscape transformation in the Northern Hemisphere Middle Pleistocene glaciation area located in the center of the Russian *** attempted to verify the regional paleogeographic model by reconstructing the Late Pleistocene incision-infill cycles at the Eastern Borisoglebsk Upland based on a comparison of inactive interfluves headwaters and actual fluvial network *** study was also aimed to determine the past extent of fluvial *** research of the actual and buried topography,Ethology and pedogenic properties of surface deposits was carrid out with remote sensing data interpretation,DGPS survey,and detailed description of geological cores *** study was followed by analysis of grain size,chemical and organic contents,microstructure,and numerical *** the available results,we propose a scenario of the fluvial network transformation at the Eastem Borisoglebsk Upland over the last 150 *** least four fluvial incision stages were determined while network extent has significantly changed through the Late *** can be generally associated with the regional base level decrease-Late Moscow,Late Valdai and Late Holocene and accompanying isolation of the Nero Lake terraces of 130 m,100-105 m and 95-98 *** stages were separated by landscape stability or aggradation periods those were asynchronous at the middle and upper parts of the fluvial *** main agent of initial valley infill appears to be local lacustrine sedimentation altered by alluvial and colluvial deposition towards the second half of *** landscape conditions variability emphasize the importance of comprehensive local correlations for regional retrospective models.

关键词： interfluve headwaters Fluvial incision-infill Cycle Pleistocene

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Anatomical and electrophysiological plasticity of locomotor networks following spinal transection in the salamander

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Neuroscience Bulletin 2013年第4期29卷 467-476页

作者： Jean-Marie Cabelguen Stéphanie Chevallier ianina Amontieva-potapova Céline Philippe Neurocentre Magendie INSERM U 862 - Bordeaux University

Recovery of locomotor behavior following spinal cord injury can occur spontaneously in some vertebrates, such as fish, urodele amphibians, and certain reptiles. This review provides an overview of the current status of our knowledge on the anatomical and electrophysiological changes occurring within the spinal cord that lead to, or are associated with the [e-expression of locomotion in spinally-transected salamanders. A better understanding of these processes will help to devise strategies for restoring locomotor function in mammals, including humans.

关键词： salamander spinal cord locomotor recovery regeneration

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Preliminary analyses of the frozen mummies of mammoth(Mammuthus primigenius),bison(Bison priscus)and horse(Equus sp.)from the Yana-indigirka Lowland,Yakutia,Russia

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integrative Zoology 2014年第4期9卷 471-480页

作者： Gennady G.BOESKOROV Olga R.potapova Eugeny N.MASHCHENKO Albert V.PROTOPOPOV Tatyana V.KUZNETSOVA Larry AGENBROAD Alexey N.TiKHONOV Diamond and Precious Metal Geology institute Siberian Branch of Russian Academy of SciencesYakutskRussia The Mammoth Site of Hot Springs Museum Hot SpringsSouth DakotaUSA Paleontological institute Russian Academy of SciencesMoscowRussia Department of the Mammoth Fauna Studies Academy of Sciences of the Sakha(Yakutia)Republic YakutskRussia M.V.Lomonosov Moscow State University MoscowRussia Zoological institute Russian Academy of SciencesSt.PetersburgRussia

The frozen bodies of a young woolly mammoth(Mammuthus primigenius),a wild horse(Equus sp.)and a steppe bison(Bison priscus)were recently found in the northern Yakutia(northeastern Siberia).All specimens have preserved bones,skin and soft *** the woolly mammoth and the Pleistocene horse were represented by partial frozen bodies,the steppe bison body was recovered in an absolutely complete *** specimens were found frozen in the permafrost,with some of the tissues *** wild horse and steppe bison are of Holocene age,and the mammoth is of Late Pleistocene age.

关键词： bison horse mammoth mummy Siberia

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Tools for Protein Structure Prediction at the *** Web Portal

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Journal of Life Sciences 2012年第10期6卷 1174-1179页

作者： Sergey Feranchuk Ulyana potapova Vladimir Potapov Dmitry Mukha Vladimir Nikolaev Sergei Belikov Met. Ltd. Minsk Kiseliova 20 Belarus Limnological instiute SB RAS Irkutsk 664033 Russia institute of Bioorganic Chemistry NAS Belarus Minsk 220141 Belarus Belozersky institute of Physico-Chemical Biology Moscow 119992 Russia

lntemet services on bioinformatics still remain a popular tool for the researchers. Here the authors present a recently developed web-site http：//*** where several tools and pipelines for protein structure prediction are implemented. The prediction of a structure for a particular protein often requires a sensitive and iterative approach, and the web-site provides an environment for this kind of work. Software that is used in the services includes both free programs available in the internet and newly developed algorithms. The service on homology screening in PDB for a structure template is implemented using an approach that is alternative to well-known BLAST algorithm and it has some advantages over BLAST. The service on homology modeling uses well-known Nest program. The service on protein energy estimate allows selecting a best template in the set of homologs and adds a functionality of fold recognition to the environment. The design of the site simplifies several of the most useful bioinformatics routines, thus making them available to a large community of researchers. Services are provided free of charge without registration, and the user＇s privacy is taken care of.

关键词： Web-service SOAP homology modeling homology screening protein folding.

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总体艺术作为设计思维

总体艺术作为设计思维

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作者：安娜（potapova Anna）中国美术学院

学位级别：硕士

本文将对艺术和设计之间的复杂关系进行深入讨论。在现代社会学和哲学理论的框架下,作者以总艺术论和设计思想为例分析艺术和设计实践的主要原则,以及这两种理论对现代社会的发展可能造成的影响。通过对总体艺术和设计思维的历史和理论... 详细信息

本文将对艺术和设计之间的复杂关系进行深入讨论。在现代社会学和哲学理论的框架下,作者以总艺术论和设计思想为例分析艺术和设计实践的主要原则,以及这两种理论对现代社会的发展可能造成的影响。通过对总体艺术和设计思维的历史和理论背景的分析,作者将进一步澄清这两个概念以及描述它们的主要创作方法。总体艺术的概念是在2000年初由邱志杰引用论述的,它指的是以社会调查为基础的艺术实践。总体艺术将克服技术和审美、艺术和生活、艺术家和观众、理论与实践之间的分裂。设计思路是设计理论不断发展的结果,它让沃尔特·格罗佩斯提出的设计重要原则起死回生,并恢复了设计师的“对世界的总体性看法”。设计思维重新思考人们的对他们所存在的物质世界的要求以及满足这些要求的创作方式。它把新科技的成果融入自己的工作,并把重点从厂家转移到了到用户。设计思维和总体艺术把文化生产看作能够改善客观现实和人们知觉的工具。两种理论追求自己的作品在一定的文化背景下的有效性,力求使人们产生一定的经验。两者的相似性植根于它们的社会背景,它们的发展和广泛推广得益于“创意阶层”的崛起和其新的修辞。我们以新修辞学的视角观察总体艺术与设计思维的时候,会发现跨学科沟通的可能性,使其相互改善、相互丰富。这两种理论不但指导我们怎么成为业内专家,更关键的是,它们都有助于我们成为幸福的工作者。

关键词：设计思路总体艺术社会调查创意阶层新修辞学

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Morphofunctional status and the role of mononuclear phagocyte system lung compartment in the pathogenesis of influenza A (H5N1) in mammals

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Advances in Bioscience and Biotechnology 2013年第11期4卷 979-985页

作者： Anna V. Kovner Oxana V. potapova Vyacheslav A. Shkurupy Alexander M. Shestopalov FSBi Research Center of Clinical and Experimental Medicine Siberian Branch of the Russian Academy of Medical Sciences No- vosibirsk Russia

influenza and other respiratory viral infections account for 80%-90% of infectious pathologies. influenza A (H5N1) virus has an apparent pneumotropism, and therefore the lung compartment of mononuclear phagocyte system plays an important role in antiviral immunity. Lung macrophages are active phagocytes expressing variety of antiviral factors. The investigation of morphofunctional status of lung macrophages and evaluation of their role in mammal antiviral response in a mouse model were performed within the study. Methods: Light microscopy using standard hematoxylin-eosin, and Van-Gizon’s picrofuchsin staining. immunohistochemistry using influenza A antigen marker specific primary antibodies, myeloperoxidase, cathepsin D, lysozyme, NO synthase, pro-inflammatory cytokines, cells of CD68 macrophage lineage, PCNA proliferative activity. Morphometric and statistical analysis. Results: influenza A virus antigen was detected in lung macrophages starting from day 1 to day 14 of infection which corresponds with the beginning of convalescence and may be suggestive of prolonged persistence of virus. On the one hand, the cytopathic effects of the virus lead to lung macrophages death mainly via apoptosis through activation of caspase cascade, including caspase-3 and caspase-9. On the other hand, the observed activation of PCNA proliferation marker, perhaps, allows to support the pool of lung macrophages not only by their recruitment from bone marrow but also by their proliferation in situ. The increase of mononuclear phagocyte system cells expressing antiviral factors depended on the stage of infection. in the early stage, there was an increase of number of cells expressing lysozyme, myeloperoxidase, cathepsin D, endothelial NO synthase (eNOS) followed by the increase of number of macrophages expressing inducible NO synthase (iNOS), pro-inflammatory cytokines and interleukins.

关键词： The influenza A (H5N1) virus Macrophages of Lungs Cathepsin D Myeloperoxidase Lysozyme iNOS eNOS TNF-α iL-6 PCNA Cell Death

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Morphofunctional Characteristics of Pulmonary Surfactant System and its Effect on immune Cells in influenza A (H1N1) Pathogenesis

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Open Journal of Pathology 2016年第1期6卷 1-7页

作者： A. V. Kovner O. V. potapova V. A. Shkurupy A. M. Shestopalov Federal State Budgetary Scientific institution Research institute of Experimental and Clinical Medicine Novosibirsk Russia

There is an annual increase of influenza-related SARi cases in winter months. Despite the high relevance of this problem, influenza pathogenesis and the role of surfactant system and its SP-A (surfactant protein A) enzyme in antiviral defense remain poorly understood. SP-A activates macrophage M1 polarization and triggers an antiviral response due to the activation of T-cells and dendritic cells. Therefore, surfactant system is an important element of infection protection and a promising therapeutic target.

关键词： influenza A (H1N1) virus Pulmonary Surfactant system SP-A M1/M2 Macrophages Antiviral Defense

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Remote-Field Manifestations of Mental Activity of the Human Brain

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World Journal of Neuroscience 2015年第2期5卷 108-114页

作者： Evgeny A. Yumatov Elena V. Bykova Olga V. potapova Aligeydar A. Ragimov Emil L. Salimov i. M. Sechenov First Moscow State Medical University Moscow Russia

The aim of the present study is to investigate mental activity of the brain. The article deals with external remote-field manifestation of the subjective state of a person. There are statistically significant results obtained which demonstrate contactless remote influence of the subjective state of a person on erythrocyte sedimentation rate in different blood groups, Rh-positive and Rh-negative blood, and under different conditions of exposure. The authors set up a hypothesis of the existence of molecular structures in the blood, which can provide a remote response to expressed subjective state of a person.

关键词： Psyche Mentality Consciousness Brain Blood Erythrocyte Sedimentation Rate (ESR)

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世界各国农业就业转型的时空分析

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河北农业大学学报(社会科学版) 2024年第5期26卷 109-121页

作者： А.А.波塔波娃 А.С.纳乌莫夫苏宁赵万鑫俄罗斯联邦总统直属国民经济与国家行政学院农粮食品政策研究中心莫斯科国立大学地理系吉林大学东北亚学院吉林大学东北亚研究中心

农业就业转型是指随着经济的发展，农业在国民经济和就业结构中的比重逐渐下降，就业人数减少，劳动力从农业部门转移到非农业部门的过程。由于各国地理环境的差异，这一进程在不同时间并不均衡，进度各异。对世界范围内的农业就业转型... 详细信息

农业就业转型是指随着经济的发展，农业在国民经济和就业结构中的比重逐渐下降，就业人数减少，劳动力从农业部门转移到非农业部门的过程。由于各国地理环境的差异，这一进程在不同时间并不均衡，进度各异。对世界范围内的农业就业转型进行系统研究具有重要意义。发达国家在19世纪中叶至20世纪上半叶已基本完成转型，拉丁美洲和北非的发展中国家在20世纪下半叶也步入转型期，而许多亚洲国家目前正在经历这一过程。由于技术进步和全球分工的深化，农业就业转型步伐不断加快。基于162个国家的统计数据，分析农业在经济和就业中的地位，考察1991年至2019年整体经济结构变化背景下的农业就业转型。研究发现，农业就业转型的时空进程可以划分为5个阶段，各国实现转型的路径各异。

关键词：农业就业就业转型变化趋势劳动生产率世界各地

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