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Effect of special types of bread with select herbal components on postprandial glucose levels in diabetic patients

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World Journal of Diabetes 2024年第4期15卷 664-674页

作者： Drasko m Gostiljac Srdjan S Popovic vesna Dimitrijevic-Sreckovic Sasa m Ilic Jelena A Jevtovic Dragan m Nikolic Ivan A Soldatovic Clinic for Endocrinology Diabetes and Metabolic DiseasesUniversity Clinical Centre of SerbiaBelgrade 11000Serbia Faculty of medicine University of BelgradeBelgrade 11000Serbia Clinic for Gastroenterology and Hepatology University Clinical Centre of SerbiaBelgrade 11000Serbia Clinic for Endocrinology Diabetes and Metabolic Diseases-Laboratory for Human Pancreatic Islets CultureUniversity Clinical Centre of SerbiaBelgrade 11000Serbia

BACKGROUND Nutrition recommendations in patients with type 2 diabetes mellitus(T2Dm)are to consume rye or integral bread instead of white bread.A positive effect on glucoregulation has been achieved by enriching food with various biologically active substances of herbal origin,so we formulated an herbal mixture that can be used as a supplement for a special type of bread(STB)to achieve better effects on postprandial glucose and insulin levels in patients with *** To compare organoleptic characteristics and effects of two types of bread on postprandial glucose and insulin levels in T2Dm *** This trial included 97 patients with T2Dm.A parallel group of 16 healthy subjects was also *** participants were given 50 g of rye bread and the same amount of a STB with an herbal mixture on 2 consecutive *** blood glucose and insulin levels were compared at the 30^(th),60^(th),90^(th) and 120th min.A questionnaire was used for subjective estimation of the organoleptic and satiety features of the two types of *** Compared to patients who consumed rye bread,significantly lower postprandial blood glucose and insulin concentrations were found in T2Dm patients who consumed *** relevant differences were found among the healthy *** estimated organoleptic and satiety characteristics are better for STB than for rye *** STB have better effects than rye bread on postprandial glucoregulation in T2Dm *** estimated organoleptic and satiety characteristics are better for STB than for rye ***,STB can be recommended for nutrition in T2Dm patients.

关键词： Special types of bread Postprandial glucoregulation Insulin Nutrition Type 2 diabetes mellitus

Impact of microstructural and Surface modifications on the Ti-45Nb Alloy’s Response to Bio-Environment

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Acta metallurgica Sinica(English Letters) 2024年第7期37卷 1215-1230页

作者： Ivana Cvijović-Alagić Slađana Laketić milošmomčilović Jovan Ciganović Jelena Bajat vesna Kojić Vinča Institute of Nuclear Sciences-National Institute of the Republic of Serbia University of BelgradeMike Petrovića Alasa 12-1411000BelgradeSerbia Faculty of Technology and metallurgy University of BelgradeKarnegijeva 411000BelgradeSerbia Oncology Institute of Vojvodina Faculty of MedicineUniversity of Novi SadPut Doktora Goldmana 4Sremska Kamenica21204Sremska KamenicaSerbia

The Ti-45Nb (mass%) alloy’s corrosive and biocompatible response in simulated physiological conditions was investigated before and after its additional high-pressure torsion (HPT) and laser irradiation processing. The grain size reduction from 2.76 µm to ~ 200 nm and the appearance of laser-induced morphologically altered and highly oxidized surface led to the significant improvement of alloy corrosion resistance and cell–implant interaction. moreover, an additional increase of the laser pulse energy from 5 to 15 mJ during the alloy irradiation in the air led to an increase in the surface oxygen content from 13.64 to 23.89% accompanied by an increase of excellent cell viability from 127.18 to 134.42%. As a result of the controlled alloy microstructural and surface modifications, the formation of protective bi-modal mixed Ti- and Nb-oxide external scale was enabled. The presence of this surface oxide scale enhanced the alloy’s resistance to corrosion deterioration and simultaneously boosted cell viability and proliferation.

关键词： Ti-45Nb alloy High-pressure torsion Laser surface scanning Corrosion resistance Biocompatible properties

不同电解条件下制备铜粉的形貌及结晶学比较分析（英文）

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Transactions of Nonferrous metals Society of China 2019年第6期29卷 1275-1284页

作者： Nebojsa D. NIKOLIC Ljiljana AVRAmOVIC Evica R. IVANOVIC vesna m. maksimoviC Zvezdana BASCAREVIC Nenad IGNJATOVIC ICTm-Department of Electrochemistry University of Belgrade Njego.eva 12 Belgrade Serbia mining and metallurgy Institute Zeleni Bulevar 35 Bor Serbia Faculty of Agriculture University of Belgrade Nemanjina 6 Belgrade-Zemun Serbia Vinca Institute of Nuclear Sciences University of Belgrade Belgrade Serbia Institute for multidisciplinary Research University of Belgrade Kneza Viseslava 1a Belgrade Serbia Institute of Technical Sciences of the Serbian Academy of Science and Arts Knez Mihailova 35/IV Belgrade Serbia

研究不同析氢条件下恒电位电解法制备铜粉的过程。采用扫描电镜(SEm)、X射线衍射(XRD)、粒度分布(PSD)和比表面积测定(SSA)对铜粉进行表征。根据电解过程析氢量的大小,形成树枝状和菜花状两种类型的颗粒。当析氢量大到足以对近电极层中... 详细信息

研究不同析氢条件下恒电位电解法制备铜粉的过程。采用扫描电镜(SEm)、X射线衍射(XRD)、粒度分布(PSD)和比表面积测定(SSA)对铜粉进行表征。根据电解过程析氢量的大小,形成树枝状和菜花状两种类型的颗粒。当析氢量大到足以对近电极层中的流体动力学条件产生强烈影响时,形成菜花状颗粒,否则形成树枝状颗粒。虽然颗粒的宏观结构差异很大,但他们的微观结构却相似,也就是说,这两种颗粒在微观层面上都是由近似球形的Cu颗粒小团聚体组成;球状形貌的存在是造成两种颗粒中Cu晶粒随机取向的原因。菜花样颗粒的比表面积是树枝状颗粒的3倍以上,其粒径则比树枝状颗粒的小很多。由此可见,强析氢条件对于铜粉制备是有益的。

关键词：电解铜颗粒比表面积粒度分布

电解液中Ni^(2+)/Co^(2+)比对电解Ni-Co合金粉末形貌、结构和磁学性能的影响

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Transactions of Nonferrous metals Society of China 2020年第4期30卷 1046-1057页

作者： vesna m.maksimoviC Vladan B.KUSIGERSKI milovan m.STOILJKOVIC Jelena R.mALETASKIC NebojSa D.NIKOLIC Institute of Nuclear Sciences “Vinca”University of BelgradeP.O.Box 522Belgrade 11001Serbia Laboratory for Advanced Nuclear Energy Institute of Innovative ResearchTokyo Institute of Technology2-12-1 OokayamaMeguro-kuTokyo 152-8550Japan ICTm-Department of Electrochemistry University of BelgradeNjegoseva 12P.O.Box 473Belgrade 11001Serbia

采用恒电流法在具有不同Ni^2+/Co^2+比(摩尔比)的硫酸盐电解液中制备镍钴(Ni-Co)合金粉末。利用扫描电镜(SEm)、X射线衍射仪(XRD)、原子发射光谱仪(AES)和基于SQUID的磁力仪检测粉末的形态、相结构、化学成分和磁学性能。当Ni^2+/Co^2+... 详细信息

采用恒电流法在具有不同Ni^2+/Co^2+比(摩尔比)的硫酸盐电解液中制备镍钴(Ni-Co)合金粉末。利用扫描电镜(SEm)、X射线衍射仪(XRD)、原子发射光谱仪(AES)和基于SQUID的磁力仪检测粉末的形态、相结构、化学成分和磁学性能。当Ni^2+/Co^2+比从0.25增加到4.0时,颗粒形貌从菜花状和树枝状转变为珊瑚状和海绵状。Ni-Co粉末的XRD分析表明,Ni/Co比降低(Co含量增加)导致结构变化:Ni^2+/Co^2+比为4.0、1.5和0.67时,粉末为面心立方(FCC)结构;Ni/Co比为0.25时,粉末为面心立方(FCC)和六方密堆(HCP)相的混合物。增加电解液中Ni含量导致电解机理发生变化:当电解液中Ni含量低于40%(质量分数)时为不规则共沉积;Ni含量为40%~60%(质量分数)时接近平衡共沉积,Ni含量高于60%(质量分数)时则为异常共沉积。所有获得的Ni-Co合金样品均为软磁材料,其磁性参数显示出直接的成分依赖性,因为矫顽力和饱和磁化强度几乎都随Co含量线性增大。

关键词： Ni-Co合金粉末电解氢形貌磁学性能

Survival trends of patients with non-metastatic gastric adenocarcinoma in the US and European countries:the impact of decreasing resection rates

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Cancer Communications 2022年第7期42卷 648-662页

作者： Lei Huang Lina Jansen Rob H.A.Verhoeven Jelle P.Ruurda Liesbet Van Eycken Harlinde De Schutter Jan Johansson mats Lindblad Tom B.Johannesen vesna Zadnik Tina Zagar Sjoerd m.Lagarde Cornelis J.Hvan de Velde Petra Schrotz-King Hermann Brenner Division of Clinical Epidemiology and Aging Research German Cancer Research Center(DKFZ)Heidelberg 69120Germany medical Faculty Heidelberg of Heidelberg University Heidelberg 69120Germany German Cancer Consortium German Cancer Research CenterHeidelberg 69120Germany Department of Research&Development Netherlands Comprehensive Cancer OrganizationUtrecht 3501 DBThe Netherlands Department of medical Oncology Amsterdam University Medical CentersAmsterdam 1105 AZThe Netherlands Department of Surgery University Medical Center UtrechtUtrecht 3508 GAThe Netherlands Belgian Cancer Registry Brussels B-1210Belgium Department of Esophageal and Gastric Surgery Lund University HospitalLund 22185Sweden Department of Clinical Science Interventionand TechnologyDivision of SurgeryKarolinska University HospitalStockholm 17176Sweden Registry Department The Cancer Registry of NorwayOslo 0379Norway Epidemiology and Cancer Registry Institute of Oncology LjubljanaLjubljana 1000Slovenia Department of Surgery Erasmus Medical Centre-University Medical Centre RotterdamRotterdam 3015 CEThe Netherlands Department of Surgical Oncology Leiden University Medical CenterLeiden 2300 RCThe Netherlands Division of Preventive Oncology German Cancer Research Center and National Center for Tumor DiseasesHeidelberg 69120Germany

Background:We previously observed decreasing resection rates of nonmetastatic gastric adenocarcinoma(GaC)in the US and some European *** and to what extent these trends affect the trends in overall survival(OS)of patients with non-metastatic GaC at the population level remain *** large international population-based cohort study aimed to assess the impact of the previously observed decreasing resection rates on multivariable-adjusted trends in the long-term OS of patients with non-metastatic ***:Individual-level data of patients with non-metastatic GaC were obtained from the national cancer registries of the Netherlands,Belgium,Sweden,Norway,and Slovenia,and the US Surveillance,Epidemiology,and End Results *** analyzed data for each country *** between year of diagnosis and OS were assessed using Cox proportional hazards regression model with adjustment for multiple prognostic variables,with and without including resection and chemotherapy as potential explanatory ***:A total of 66,398 non-metastatic GaC patients diagnosed in 2003-2016 were analyzed,with an accumulated follow-up of 172,357 *** adjustment for resection,OS was improved only slightly in the US[hazard ratio(HR)_(per year)=0.99;HR_(≥vs.mprovement was observed in the investigated European countries,with OS even worsening in Sweden(HR_(per year)=1.03;HR_(≥vs.me stronger in the US(HR_(per year)=0.98;HR_(≥vs.mporal trend became insignificant in *** Slovenia(HR_(per year)=0.99;HR_(≥vs.mproved OS over time emerged after resection *** OS in patients undergoing resection was observed in the US,the Netherlands,and *** for chemotherapy did not alter the observed *** analyses by tumor location showedm

关键词： gastric adenocarcinoma resection rate adjusted overall survival temporal trend prognostic factors international population-based cohort study

Effi ciency of phosphorus accumulation by plankton,periphyton developed on submerged artifi cial substrata and metaphyton:in-situ observation in two shallow ponds

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Journal of Oceanology and Limnology 2021年第3期39卷 928-945页

作者： marija PEĆIĆ Slađana POPOVIĆ vesna mILUTINOVIĆ Gordana SUBAKOV SImIĆ Ivana TRBOJEVIĆ Dragana PREDOJEVIĆ Institute of Botany and Botanical Garden‘Jevremovac’ Faculty of BiologyUniversity of BelgradeBelgrade 11000Serbia Institute of Chemistry Technology and MetallurgyScientific InstitutionNational InstituteCenter for Ecology and TechnoeconomicsUniversity of BelgradeBelgrade 11000Serbia Institute of Public Health of Belgrade Belgrade 11000Serbia

Phosphorus overenrichment of shallow ponds prevailing in wetlands leads to their eutrophication causing the collapse of those vulnerable *** potential of phosphorus accumulation by periphyton developed on artificial substrata has been investigated in two shallow ponds(Bara?ka and?iroki Rit)in northwest Serbia and compared to the same ability of plankton and *** periphyton substrate carrier has been submerged from may to *** continuously(CS)and monthly developed(mS)periphyton were *** component of all investigated communities has been qualitatively *** accumulation of only 14.7 mg TP/m^(2) was recorded in three-month exposed periphyton *** exposed from July to August reached maximal 12.7 mg TP/m^(2).Plankton community that was characterized by more diverse and abundantly developed algal component was more effective in phosphorus accumulation(0.7 mg/g dry weight)in comparison with dominantly inorganic and diatom-dominated periphyton in Bara?*** conditions caused by recent revitalization(dredging organic matter and mud from pond basin—redigging)as well as rapid desiccation of?iroki Rit disabled making an unambiguous conclusion about the efficiency of phosphorus accumulation among different communities,but suggested slight potential of phosphorus harvesting by metaphyton in this *** to the shorter exposure time that brings the reduced risk of unpredictable changes in the ecosystem,as well as the considerable amount of accumulated phosphorus,large-scale application of one-month exposed periphyton developed on artificial substrates would be more advisable for phosphorus harvesting in nutrient affected shallow ponds.

关键词： periphyton phosphorus accumulation shallow ponds (phyto)plankton metaphyton eutrophication

A deep convolutional neural network for real-time full profile analysis of big powder diffraction data

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npj Computational materials 2021年第1期7卷 671-679页

作者： Hongyang Dong Keith T.Butler Dorota matras Stephen W.T.Price Yaroslav Odarchenko Rahul Khatry Andrew Thompson vesna middelkoop Simon D.m.Jacques Andrew m.Beale Antonis Vamvakeros Department of Chemistry University College London20 Gordon StreetLondon WC1H 0AJUnited Kingdom ScimL Scientific Computer DivisionSTFCRutherford Appleton LaboratoryHarwell OX110QXUnited Kingdom Finden Limited Merchant House5 East St Helens StreetAbingdon OX145EGUnited Kingdom National Physical Laboratory Hampton RoadTeddington TW110LWUnited Kingdom Flemish Institute for Technological Research VITO NVBoeretang 200Mol 2400Belgium Research Complex at Harwell Rutherford Appleton LaboratoryHarwell Science and Innovation CampusDidcotOX110FA OxfordshireUnited Kingdom Present address:Diamond Light Source Harwell Science and Innovation CampusDidcotOxfordshire OX110DEUnited Kingdom Present address:The Faraday Institution Quad OneHarwell Science and Innovation CampusOX110RA OxfordshireUnited Kingdom

We present Parameter Quantification Network(PQ-Net),a regression deep convolutional neural network providing quantitative analysis of powder X-ray diffraction patterns from multi-phase *** network is tested against simulated and experimental datasets of increasing complexity with the last one being an X-ray diffraction computed tomography dataset of a multi-phase Ni-Pd/CeO_(2)-ZrO_(2)/Al_(2)O_(3) catalytic material system consisting of ca.20,000 diffraction *** is shown that the network predicts accurate scale factor,lattice parameter and crystallite size maps for all phases,which are comparable to those obtained through full profile analysis using the Rietveld method,also providing a reliable uncertainty measure on the *** main advantage of PQNet is its ability to yield these results orders of magnitude faster showing its potential as a tool for real-time diffraction data analysis during in situ/operando experiments.

关键词： network powder analysis

Dynamic control of high-voltage actuator arrays by light-pattern projection on photoconductive switches

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微系统与纳米工程(英文) 2023年第3期9卷 387-396页

作者： vesna Bacheva Amir Firouzeh Edouard Leroy Aiste Balciunaite Diana Davila Israel Gabay Federico Paratore moran Bercovici Herbert Shea Govind Kaigala Faculty of mechanical Engineering Technion-Israel Institute of Technology3200003 HaifaIsrael IBm Research Europe-Zurich Säumerstrasse 48803 RüschlikonSwitzerland Soft Transducers Laboratory(LmTS) Ecole Polytechnique Fédérale de Lausanne(EPFL)2000 NeuchâtelSwitzerland Present address:Laboratory of Soft materials and Interfaces ETH Zürich8093 ZürichSwitzerland Present address:School of Biomedical Engineering Vancouver Prostate CentreLife Sciences InstituteUniversity of British ColumbiaVancouverCanada

The ability to control high-voltage actuator arrays relies, to date, on expensive microelectronic processes or on individual wiring of each actuator to a single off-chip high-voltage switch. Here we present an alternative approach that uses on-chip photoconductive switches together with a light projection system to individually address high-voltage actuators. Each actuator is connected to one or more switches that are nominally OFF unless turned ON using direct light illumination. We selected hydrogenated amorphous silicon (a-Si:H) as our photoconductive material, and we provide a complete characterization of its light to dark conductance, breakdown field, and spectral response. The resulting switches are very robust, and we provide full details of their fabrication processes. We demonstrate that the switches can be integrated into different architectures to support both AC and DC-driven actuators and provide engineering guidelines for their functional design. To demonstrate the versatility of our approach, we demonstrate the use of the photoconductive switches in two distinctly different applications—control of µm-sized gate electrodes for patterning flow fields in a microfluidic chamber and control of cm-sized electrostatic actuators for creating mechanical deformations for haptic displays.

关键词： projection light sized

Preparatory training attenuates drastic response of the insulin-like growth factor binding protein 1 at the point of maximal oxygen consumption in handball players

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Journal of Sport and Health Science 2017年第3期6卷 372-377页

作者： Olgica Nedic milos Sunderic Goran miljus Zoran Valdevit Vladimir Jakovljevic marija Glibetic vesna Vucic Institute for the Application of Nuclear Energy University of BelgradeBelgrade 11080Serbia Faculty of Sport and Physical Education University of BelgradeBelgrade 11000Serbia Department of Physiology Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Centre of Research Excellence in Nutrition and metabolism Institute for Medical ResearchUniversity of BelgradeBelgrade 11000Serbia

Background:Intensive exercise changes physiological need for glucose and several biochemical pathways responsible for its metabolism *** them are those which involve insulin,insulin-like growth factor(IGF-1),and IGF-binding proteins(IGFBPs).Different types and degrees of exercise,as well as an athlete's fitness,may induce a range of responses regarding concentrations and time needed for the *** idea of the work was to find out whether and how insulin/IGF axis responds to additional physical activity in the already trained subjects and if so,is the adaptation potentially beneficial from the aspect of metabolic ***:The effect of 4-week intensive training on campus(preparatory training) on the levels of insulin,IGF-1,and IGFBPs during maximal progressive exercise test(mPET) on a treadmill was compared to the results obtained during mPET conducted after a regular training season of a female elite handball team(n = 17,age:17 ± 1 years,height:171 ± 8 cm,weight:65 ± 8 kg,body mass index:22 ± 1 kg/m^2 at the beginning of the study;there were no significant changes at the end).Serum samples were obtained from players immediately before the test(basal),at the end of the test after reaching the point of maximal oxygen consumption(VO_(2max)),and after ***:The concentration of insulin decreased at VO_(2max),but remained higher in players after preparatory training(12.2 ± 2.5 m U/L vs.8.9 ± 4.4 m U/L,p = 0.049).The level of IGFBP-1 decreased in players at VO_(2max) in either case of training,but it remained much higher in tests performed after the preparatory regime than before(p = 0.029).Concentrations of IGF-1,IGFBP-2,-3,and-4 did not change ***:The inverse relation between insulin and IGFBP-1 was lost during mPET,as these 2 molecules changed in the same *** results obtained suggest less severe stress-induced depression of insulin and IGFBP-1 after preparatory *** another metabolic mechanism

关键词：女性 IGF 有约束力的蛋白质(IGFBP ) 胰岛素像胰岛素的生长因素我(IGF-1 ) 进步锻练测试 VO 2max