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Agreement of angle closure assessments between gonioscopy, anterior segment optical coherence tomography and spectral domain optical coherence tomography

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International Journal of Ophthalmology(English edition) 2015年第2期8卷 342-346页

作者： Elton Lik Tong Tay vernon khet yau yong Boon Ang Lim Stelson Sia Elizabeth Poh Ying Wong Leonard Wei Leon Yip Department of Ophthalmology Tan Tock Seng Hospital Republic of Singapore Air Force Aeromedical Centre Cardinal Santos Medical Center

AIM: To determine angle closure agreements between gonioscopy and anterior segment optical coherence tomography(AS-OCT), as well as gonioscopy and spectral domain OCT(SD-OCT). A secondary objective was to quantify inter-observer agreements of AS-OCT and SD-OCT ***: Seventeen consecutive subjects(33 eyes)were recruited from the study hospital’s Glaucoma *** was performed by a glaucomatologist masked to OCT results. OCT images were read independently by 2 other glaucomatologists masked to gonioscopy findings as well as each other’s analyses of OCT ***: Totally 84.8% and 45.5% of scleral spurs were visualized in AS-OCT and SD-OCT images respectively(P <0.01). The agreement for angle closure between AS-OCT and gonioscopy was fair at k =0.31(95% confidence interval, CI: 0.03-0.59) and k =0.35(95%CI: 0.07-0.63) for reader 1 and 2 respectively. The agreement for angle closure between SD-OCT and gonioscopy was fair at k =0.21(95% CI: 0.07-0.49) and slight at k =0.17(95% CI: 0.08-0.42) for reader 1 and 2 respectively. The inter-reader agreement for angle closure in AS-OCT images was moderate at 0.51(95% CI: 0.13-0.88). The inter-reader agreement for angle closure in SD-OCT images was slight at 0.18(95% CI: 0.08-0.45).CONCLUSION: Significant proportion of scleral spurs were not visualised with SD-OCT imaging resulting in weaker inter-reader agreements. Identifying other angle landmarks in SD-OCT images will allow more consistent angle closure assessments. Gonioscopy and OCT imaging do not always agree in angle closure assessments but have their own advantages, and should be used together and not exclusively.

关键词： anterior segment imaging spectral domain imaging angle closure assessment

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Prospective 12‑month outcomes of combined iStent inject implantation and phacoemulsification in Asian eyes with normal tension glaucoma

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Eye and Vision 2024年第6期10卷 1-11页

作者： Bryan Chin Hou Ang Wenqi Chiew Vivien Cherng Hui Yip Chun Hau Chua Wei Shan Han Ivan O’Neill CTecson Jeanne Joyce Ogle Boon Ang Lim Owen Kim Hee Elton Lik yong Tay vernon khet yau yong Hon Tym Wong Leonard Wei Leon Yip National Healthcare Group Eye Institute Tan Tock Seng HospitalSingaporeSingapore National Healthcare Group Eye Institute Woodlands Health CampusSingaporeSingapore yong Loo Lin School of Medicine National University of SingaporeSingaporeSingapore Cardinal Santos Medical Centre ManilaPhilippines Hesed Eye Specialists SingaporeSingapore

Background:Glaucoma is the leading cause of irreversible *** tension glaucoma(NTG)is a subset of open-angle glaucoma,demonstrating glaucomatous optic nerve damage in the absence of raised intraocular pressure(IOP).NTG is more prevalent in Asian *** generally slow-progressing,NTG may be associated with significant central visual field *** recent years,minimally invasive glaucoma surgery has been added to the armamentarium of glaucoma *** prospective study aims to evaluate 12-month surgical outcomes of combined iStent inject(Glaukos Corporation,Laguna Hills,CA)implantation and phacoemulsification in Asian eyes with ***:This is a prospective,single-centre case series of 30 eyes followed up until 12 months after *** measures included IOP,number of glaucoma medications,best-corrected visual acuity(BCVA)and intra and postoperative ***:Mean age of subjects was 73.1±6.3 *** were ethnic Chinese(n=27,90%).Baseline medicated mean IOP was 13.8±2.4 mmHg and mean number of glaucoma medications was 1.3±*** Humphrey visual field mean deviation was−13.7±*** mean IOP reduction at all timepoints from postoperative month(POM)3 onwards was statistically significant(all P<0.05),with mean reduction of 1.2 mmHg(95%CI:0.1–2.2,P=0.037)by *** was statistically significant reduction in mean number of medications from postoperative day(POD)1 onwards(all P<0.05),with mean decrease of 1.0 medication(95%CI:0.9–1.1,P<0.001)by *** POM12,25(83.3%)eyes were ***(10%)eyes had stent occlusion by iris requiring laser *** eye had gross hyphema which resolved on conservative management before *** BCVA improved from the baseline 0.3±0.3 logMAR to 0.1±0.1 logMAR postoperatively(P<0.001).There were no major adverse or sight-threatening *** eyes required further glaucoma surgery during the 12-month follow-up ***:Asian eyes with NTG which underwent

关键词： iStent inject Normal tension glaucoma Minimally invasive glaucoma surgery Asian

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